\n\n5 mg, 10 mg film-coated tablets
ambrisentan<\/p>\n\n\n\n
Ambrisentan Accord contains the active substance ambrisentan. It belongs to a group of medicines called other antihypertensive drugs (used to treat high blood pressure ).<\/p>\n\n\n\n
It is used to treat pulmonary arterial hypertension (PAH) in adults. PAH is high blood pressure in the blood vessels (pulmonary arteries) that transport blood from the heart to the lungs. In people with PAH, these arteries become narrower so that the heart has to work harder to pump blood through them. This makes you feel tired, dizzy, and out of breath.<\/p>\n\n\n\n
Ambrisentan Accord dilates the pulmonary arteries and makes it easier for the heart to pump blood through them. This lowers blood pressure and relieves symptoms.<\/p>\n\n\n\n
Ambrisentan Accord can also be used in combination with other medicines used to treat PAH.<\/p>\n\n\n\n
Ambrisentan contained in Ambrisentan Accord may also be approved for the treatment of other diseases not mentioned in this product information. Ask your doctor, pharmacist, or other healthcare professional if you have any further questions and always follow their instructions.
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Do not take Ambrisentan Accord:<\/p>\n\n\n\n
Talk to your doctor before taking this medicine if you have any<\/p>\n\n\n\n
\u2192 <\/strong>Your doctor will decide<\/strong> if Ambrisentan Accord is suitable for you. You need to take blood samples regularly<\/em><\/p>\n\n\n\n Before you start taking Ambrisentan Accord and regularly while you are taking it, your doctor will take a blood test to check:<\/p>\n\n\n\n \u2192<\/strong> It is important that you leave these regular blood tests as long as you take the Ambrisentan Accord. Signs that your liver may not be working properly are for example:<\/p>\n\n\n\n If you notice any of these signs: \u2192 Tell your doctor immediately.<\/strong><\/p>\n\n\n\n Ambrisentan Accord is not recommended for children and adolescents under 18 years of age as safety and efficacy are not known for this age group.<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n Your doctor may need to adjust your dose of Ambrisentan Accord if you start taking ciclosporin A (a medicine used after transplantation or to treat psoriasis ). If you are taking rifampicin (an antibiotic used to treat serious infections ), your doctor will monitor you more closely when you start taking Ambrisentan Accord.<\/p>\n\n\n\n If you are taking other medicines used to treat PAHs (eg iloprost, epoprostenol, sildenafil) your doctor may need to check you more closely. \u2192 <\/strong>Tell your doctor or pharmacist<\/strong> if you are taking any of these medicines.<\/p>\n\n\n\n Pregnancy<\/strong><\/em><\/p>\n\n\n\n Ambrisentan Accord can harm the unborn baby if you become pregnant before, during, or shortly after treatment. \u2192 If it is possible that you may become pregnant, use a reliable contraceptive wh<\/strong>ile you are taking Ambrisentan Accord. Discuss this with your doctor. \u2192 Do not take Ambrisentan Accord if you are pregnant or planning to become pregnant.<\/strong> \u2192 If you become pregnant or suspect that you may be pregnant while taking Ambrisentan Accord, contact a doctor immediately.<\/strong> If you are a woman and could become pregnant, your doctor will ask you to do a pregnancy test<\/strong> before you start taking Ambrisentan Accord and regularly while you are taking this medicine. Breast-feeding<\/em><\/strong><\/p>\n\n\n\n It is not known if Ambrisentan Accord passes into breast milk. \u2192 <\/strong>Do not breast-feed while taking Ambrisentan Accord. <\/strong>Discuss this with your doctor. Fertility<\/strong><\/em><\/p>\n\n\n\n If you are a man taking Ambrisentan Accord, there may be a risk that Ambrisentan Accord will reduce the number of sperm. Talk to your doctor if you have any questions about this.<\/p>\n\n\n\n Ambrisentan Accord can cause side effects, such as low blood pressure, dizziness, fatigue (see section 4) which may affect your ability to drive or use machines. The symptoms of your illness may also make you less fit to drive or use machines. \u2192 Do not drive or use machines unless you are feeling well.<\/strong> You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n Ambrisentan Accord tablets contain small amounts of a sugar called lactose. If you have been told by your doctor that you have an intolerance to some sugars: \u2192 <\/strong>Contact your doctor<\/strong> before taking Ambrisentan Accord. Ambrisentan Accord tablets contain lecithin derived from soy. If you are allergic to soy, do not take this medicine (see section 2 \u201cDo not take Ambrisentan Accord\u201d). Ambrisentan Accord tablets contain a dye called Allura red AC aluminum lacquer (E129) which may cause allergic reactions (see section 4). This medicine contains less than 1 mmol (23 mg) sodium per tablet, ie it is essentially ‘sodium-free’.<\/p>\n\n\n\n Always use this medicine exactly as your doctor or pharmacist has told you. <\/strong>Ask your doctor or pharmacist if you are unsure. How much Ambrisentan Accord to take<\/strong> The usual dose of Ambrisentan Accord is one 5 mg tablet once a day. Your doctor may decide to increase the dose one to 10 mg once a day. If you are taking ciclosporin A, do not take more than one 5 mg Ambrisentan Accord tablet once a day. How to take Ambrisentan Accord<\/strong> It is best to take the tablet at the same time each day. Swallow the tablet whole with a glass of water. The tablet should not be split, crushed, or chewed. You can take Ambrisentan Accord with or without food. Taking out a tablet<\/strong> The tablets are supplied in special packages to prevent children from taking them out. If you take too many tablets, there is a greater risk of side effects such as headaches, hot flashes, dizziness, nausea, or low blood pressure, which may cause dizziness.<\/p>\n\n\n\n \u2192 <\/strong>Ask your doctor or pharmacist for advice<\/strong> if you are taking more tablets than prescribed. <\/p>\n\n\n\n If you forget to take a dose of Ambrisentan Accord, take it as soon as possible. Then continue to take the medicine as prescribed. \u2192 Do not take a double dose to make up for a forgotten dose.<\/strong><\/p>\n\n\n\n Do not stop taking Ambrisentan Accord without consulting your doctor.<\/strong> Ambrisentan Accord is a treatment that you must continue to take to control your PAH. \u2192 Do not stop taking Ambrisentan Accord without your doctor’s agreement.<\/strong> If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them. Conditions that you and your doctor must be aware of:<\/strong> Allergic reactions<\/strong><\/p>\n\n\n\n This is a common side effect that may affect up to 1 in 10<\/strong> people. You may get a rash or itching and swelling (usually on the face, lips, tongue, or throat), which may cause difficulty breathing or swallowing. Swelling ( edema ), especially of the ankles and feet<\/strong><\/p>\n\n\n\n This is a very common side effect that may affect more than 1 in 10<\/strong> people. Heart failure<\/strong><\/p>\n\n\n\n This is because the heart does not pump out enough blood which leads to shortness of breath, extreme fatigue, and swollen ankles and legs. It is a common side effect that may affect up to 1 in 10<\/strong> people. Anemia (decreased number of red blood cells )<\/strong><\/p>\n\n\n\n This is a blood disease that can lead to fatigue, weakness, shortness of breath, and general malaise. Sometimes this requires a blood transfusion. It is a very common side effect that may affect more than 1 in 10<\/strong> people. Hypotension (low blood pressure )<\/strong><\/p>\n\n\n\n This can cause dizziness. It is a common side effect that may affect up to 1 in 10<\/strong>people. \u2192 Tell<\/strong> your doctor immediately if<\/strong> you get these side effects or if they occur suddenly after using Ambrisentan Accord. It is important that you take regular blood tests,<\/strong> to check if you have anemia and that your liver is functioning properly. Make sure you have also read the information in section 2<\/strong> under “You need to have blood tests regularly” and “Signs that your liver may not be working properly”. Other side effects include<\/strong> Very common side effects:<\/strong><\/p>\n\n\n\n In combination with tadalafil (another medicine used to treat PAH)<\/strong><\/p>\n\n\n\n In addition to the above:<\/p>\n\n\n\n Common side effects:<\/strong><\/p>\n\n\n\n In combination with tadalafil (another medicine used to treat PAH)<\/strong><\/p>\n\n\n\n In addition to the above, with the exception of abnormal liver function values:<\/p>\n\n\n\n Uncommon side effects:<\/strong><\/p>\n\n\n\n In combination with tadalafil<\/strong><\/p>\n\n\n\n Reporting of side effects<\/em><\/p>\n\n\n\n If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly to the producing company. By reporting side effects, you can help increase drug safety information. <\/p>\n\n\n\n Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. The expiration date is the last day of the specified month. No special storage instructions. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Ambrisentan Accord 5 mg film-coated tablets<\/em><\/p>\n\n\n\n Ambrisentan Accord 10 mg film-coated tablets<\/em><\/p>\n\n\n\n Ambrisentan Accord 5 mg film-coated tablet<\/em><\/p>\n\n\n\n Ambrisentan Accord 5 mg film-coated tablet is a light pink, round, biconvex tablet debossed with \u201c5\u201d on one side and approximately 7.0 mm in size. Ambrisentan Accord 10 mg film-coated tablet<\/em><\/p>\n\n\n\n Ambrisentan Accord 10 mg film-coated tablet is a dark pink, oval, biconvex tablet debossed with \u201c10\u201d on one side and approximately 9.9 mm x 5.0 mm in size. Ambrisentan Accord is available as 5 mg and 10 mg film-coated tablets in single-dose blister packs (blisters of aluminum\/aluminum foil or blisters of PVC \/ PVCD \/ aluminum foil) of 10 x 1 or 30 x 1 tablet. Not all pack sizes may be marketed.<\/p>\n\n\n\n Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n Accord Healthcare BV<\/p>\n\n\n\n Winthontlaan 200<\/p>\n\n\n\n 3526 VK Utrecht<\/p>\n\n\n\n Netherlands Manufacturer<\/strong><\/p>\n\n\n\n Delorbis Pharmaceuticals Limited<\/p>\n\n\n\n 17 Athinon Street, Ergates Industrial Area<\/p>\n\n\n\n 2643 Ergates Nicosia,<\/p>\n\n\n\n Cyprus Accord Healthcare Limited<\/p>\n\n\n\n Sage House, 319 Pinner Road<\/p>\n\n\n\n North Harrow, Middlesex HA1 4HF,<\/p>\n\n\n\n UK Laboratori Fundaci\u00f3 Dau 08040 Barcelona, Wessling Hungary,<\/p>\n\n\n\n Anonymous u. 6., Budapest, 1045,<\/p>\n\n\n\n Hungary<\/p>\n","protected":false},"excerpt":{"rendered":" Ambrisentan Accord contains the active substance ambrisentan. It belongs to a group of medicines called other antihypertensive drugs (used to treat high blood pressure ).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,2201],"tags":[10680,10695,10698,10683,10684,10699,10697,10682,10681,10696],"class_list":["post-5311","post","type-post","status-publish","format-standard","hentry","category-medicines","category-a","tag-ambrisentan","tag-ambrisentan-accord","tag-ambrisentan-accord-tablet","tag-ambrisentan-tablet","tag-side-effects-of-ambrisentan","tag-side-effects-of-ambrisentan-accord","tag-what-ambrisentan-accord-is-used-for","tag-what-ambrisentan-is-used-for","tag-what-is-ambrisentan","tag-what-is-ambrisentan-accord"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5311","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5311"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5311\/revisions"}],"predecessor-version":[{"id":12760,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5311\/revisions\/12760"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5311"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5311"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5311"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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Other medicines and Ambrisentan Accord<\/h2>\n\n\n\n
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<\/p>\n\n\n\nAmbrisentan Accord contains excipients<\/h2>\n\n\n\n
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<\/p>\n\n\n\nHow to use Ambrisentan Accord<\/h2>\n\n\n\n
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<\/p>\n\n\n\nIf you use more Ambrisentan Accord than you should <\/h2>\n\n\n\n
<\/p>\n\n\n\nIf you forget to use Ambrisentan Accord<\/h2>\n\n\n\n
<\/p>\n\n\n\nIf you stop using Ambrisentan Accord<\/h2>\n\n\n\n
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<\/p>\n\n\n\n4. Possible side effects<\/h2>\n\n\n\n
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<\/p>\n\n\n\n5. How to store Ambrisentan Accord<\/h2>\n\n\n\n
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<\/p>\n\n\n\n6. Contents of the packaging and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
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<\/p>\n\n\n\nMarketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
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C \/ C, 12-14 Pol. Ind. Zona Franca,<\/p>\n\n\n\n
Spain
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