{"id":5225,"date":"2020-12-14T06:11:46","date_gmt":"2020-12-14T06:11:46","guid":{"rendered":"https:\/\/zeepedia.com\/?p=5225"},"modified":"2021-08-02T07:05:04","modified_gmt":"2021-08-02T07:05:04","slug":"allopurinol-accord","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/allopurinol-accord\/","title":{"rendered":"Allopurinol Accord &#8211; Allopurinol uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n100 mg and 300 mg&nbsp;tablets&nbsp;<br>allopurinol<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Allopurinol Accord is and what it is used for<\/h2>\n\n\n\n<p>Allopurinol Accord contains the active substance allopurinol.&nbsp;This medicine belongs to a group of medicines called enzyme inhibitors.&nbsp;They work by regulating the speed of certain chemical processes in the body.<br><\/p>\n\n\n\n<p>Allopurinol Accord is used to treat conditions associated with an excess of&nbsp;uric acid&nbsp;in the body, including&nbsp;gout, certain types of kidney disease and&nbsp;kidney stones, cancer, and certain enzyme disorders that lead to the accumulation of too much&nbsp;uric acid.<\/p>\n\n\n\n<p>Allopurinol contained in the Allopurinol Accord may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Allopurinol Accord<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Allopurinol Accord<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to allopurinol or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Allopurinol Accord<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have or have had liver or kidney disease<\/li><li>if you are taking medicines for heart disease or high&nbsp;blood pressure&nbsp;(&nbsp;diuretics and\/or medicines called&nbsp;ACE inhibitors&nbsp;)<\/li><li>if you have an ongoing gout attack<\/li><li>if you are of Han Chinese, Thai or Korean descent<\/li><li>if you have thyroid problems.<\/li><\/ul>\n\n\n\n<p>Take special care with Allopurinol Accord:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have&nbsp;kidney stones.&nbsp;The kidney stones&nbsp;can become smaller and can risk entering and blocking the urinary tract, which can cause problems.<\/li><li>Severe skin rash (hypersensitivity&nbsp;syndrome&nbsp;and&nbsp;Stevens-Johnson syndrome, also known as&nbsp;toxic epidermal necrolysis&nbsp;) have been reported with the use of allopurinol.&nbsp;The rash can often include sores in the mouth, throat, nose, and genitals as well as conjunctivitis (red and swollen eyes).&nbsp;Before these severe skin rashes, you often get&nbsp;flu-like symptoms such&nbsp;as fever, headache, and body aches.&nbsp;The rash can develop into widespread blistering and scaly skin.&nbsp;If you get a rash or these skin symptoms, stop taking allopurinol, and contact a doctor immediately.<\/li><li>if you have cancer or Lesch-Nyhan syndrome, the amount of&nbsp;uric acid&nbsp;in your urine may increase.&nbsp;To avoid this, it is therefore important to drink enough so that the urine is diluted.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Use in children is rarely justified, except in certain types of cancer (especially&nbsp;leukemia&nbsp;) and certain enzyme diseases such as Lesch-Nyhan syndrome.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Allopurinol Accord<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>drugs used to&nbsp;inhibit the&nbsp;immune system (immunosuppressive agents), e.g.&nbsp;6 \u2011 mercaptopurine, azathioprine, and cyclosporine<\/li><li>adenine arabinoside (vidarabine), which is used to treat&nbsp;herpes&nbsp;or chickenpox<\/li><li>other drugs to treat&nbsp;gout, such as probenecid<\/li><li>acetylsalicylic acid&nbsp;(or related medicines called salicylates)<\/li><li>chloropropamide, for the treatment of&nbsp;diabetes<\/li><li>blood-thinning drugs (&nbsp;anticoagulants&nbsp;), e.g.&nbsp;warfarin<\/li><li>drugs for the treatment of&nbsp;epilepsy, e.g.&nbsp;phenytoin<\/li><li>theophylline, which is used for breathing problems<\/li><li>antibiotics&nbsp;(ampicillin or amoxicillin)<\/li><li>drugs used to treat cancer<\/li><li>didanosine used to treat&nbsp;HIV&nbsp;&#8211;&nbsp;infection<\/li><li>medicines for heart problems or high&nbsp;blood pressure, such as&nbsp;ACE inhibitors&nbsp;or&nbsp;diuretics&nbsp;(&nbsp;diuretics&nbsp;)<\/li><li>aluminum hydroxide, as it may reduce the effect of allopurinol.&nbsp;There should be an interval of at least 3 hours between taking these two drugs.<\/li><li>cytotoxic drugs (eg cyclophosphamide, doxorubicin, bleomycin, procarbazine, and alkyl halides), as&nbsp;blood dyscrasias&nbsp;(imbalance in blood composition), are more common when these drugs are taken at the same time as allopurinol.&nbsp;Blood cell counts should therefore be performed at regular intervals.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Allopurinol is excreted in human milk.&nbsp;Allopurinol is not recommended during breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Allopurinol Accord can make you drowsy and affect coordination.&nbsp;Do not drive or use any tools or machines until you know how the medicine affects you.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Allopurinol Accord contains lactose<\/h2>\n\n\n\n<p>This medicine contains&nbsp;lactose&nbsp;(a type of sugar).&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Allopurinol Accord<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Consult a doctor if you are unsure.<br><\/p>\n\n\n\n<p>The appropriate amount of Allopurinol Accord can vary greatly from individual to individual.&nbsp;Your doctor will decide which&nbsp;dose&nbsp;of Allopurinol Accord is best for you.<br><\/p>\n\n\n\n<p>The usual starting dose is 100-300 mg daily, which can be taken as a single dose.&nbsp;Dose&nbsp;one can be increased to 900 mg daily, depending on the severity of your condition.<br><\/p>\n\n\n\n<p>If the daily&nbsp;dose&nbsp;is higher than 300 mg, your doctor may&nbsp;prescribe the&nbsp;medicine in evenly divided&nbsp;doses&nbsp;during the day to avoid any&nbsp;side effects&nbsp;from the stomach and intestines.<br><\/p>\n\n\n\n<p>If you are older or if you have impaired liver or kidney function, your doctor may prescribe a lower&nbsp;dose&nbsp;or decide that there should be a long time between&nbsp;doses.&nbsp;If you receive&nbsp;dialysis&nbsp;two or three times a week, your doctor may prescribe a&nbsp;dose&nbsp;of 300 mg or 400 mg to be taken immediately after&nbsp;dialysis.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Children and adolescents under 15 years of age: 10 to 20 mg\/kg body weight\/day up to a maximum of 400 mg daily, divided into three&nbsp;doses.&nbsp;Use in children is rarely justified, except in malignant conditions (especially&nbsp;leukemia&nbsp;) and certain enzyme diseases, e.g.&nbsp;Lesch-Nyhan syndrome.<\/p>\n\n\n\n<p>Method of administration<\/p>\n\n\n\n<p>Allopurinol Accord should be taken by mouth.<\/p>\n\n\n\n<p>The tablets should be taken together with a glass of water to make them easier to swallow.<\/p>\n\n\n\n<p>You should take the tablets after a meal to reduce the risk of&nbsp;side effects&nbsp;such as nausea and vomiting.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Allopurinol Accord<\/h2>\n\n\n\n<p>If you forget to take a&nbsp;dose, take it as soon as you remember.&nbsp;However, skip the missed&nbsp;dose&nbsp;one if it is soon time to take the next&nbsp;dose.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Allopurinol Accord<\/h2>\n\n\n\n<p>Do not stop taking Allopurinol Accord unless your doctor tells you to.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Hypersensitivity<\/strong><br><\/p>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people)<\/p>\n\n\n\n<p>Tell&nbsp;your doctor&nbsp;<strong>immediately<\/strong>&nbsp;if you get any of the following symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a reaction with e.g.&nbsp;scaly skin, boils or sores on the lips and mouth<\/li><li>or very rare symptoms such as sudden wheezing, heart palpitations, or pressure over the chest and collapse.<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fever and chills, headache, muscle aches (&nbsp;flu-like symptoms&nbsp;), and general malaise<\/li><li>severe&nbsp;hypersensitivity reactions&nbsp;with fever, rash, joint pain, abnormal blood values \u200b\u200b, and liver function values \u200b\u200b(these may be signs of intolerance involving several organs)<\/li><li>bleeding on the lips, eyes, mouth, nose, or genitals<\/li><li>skin changes, e.g.&nbsp;sores on the mouth, throat, nose, and genitals as well as conjunctivitis (red and swollen eyes), scattered blisters, or scaling.<\/li><\/ul>\n\n\n\n<p><strong>Very rare<\/strong>&nbsp;&nbsp;(may affect up to 1 in 10,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe&nbsp;allergic reaction&nbsp;with swelling of the face or throat<\/li><li>Severe, possibly life-threatening&nbsp;allergic reaction.<\/li><\/ul>\n\n\n\n<p>These symptoms may mean that you are allergic to Allopurinol Accord.&nbsp;Do not take more tablets unless your doctor tells you to.<br><\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><br><\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rash<\/li><li>elevated levels of thyroid-stimulating hormone&nbsp;in the blood.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>nausea or vomiting<\/li><li>abnormal liver function values.<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>liver problems, such as&nbsp;hepatitis.<\/li><\/ul>\n\n\n\n<p><strong>Very rare<\/strong>&nbsp;(may affect up to 1 in 10,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>high body temperature<\/li><li>blood in the urine (&nbsp;hematuria&nbsp;)<\/li><li>high blood cholesterol levels (&nbsp;hyperlipidemia&nbsp;)<\/li><li>a general feeling of illness or weakness.<\/li><li>weakness, numbness, unstable legs, feeling unable to move the muscles (paralysis), or loss of consciousness<\/li><li>headache, dizziness, drowsiness, or blurred vision<\/li><li>chest pain (angina), high&nbsp;blood pressure,&nbsp;or slow&nbsp;heart rate<\/li><li>accumulation of fluid leading to swelling (&nbsp;edema&nbsp;), especially of the ankles<\/li><li>abnormal glucose metabolism (&nbsp;diabetes&nbsp;).&nbsp;Your doctor may want to measure your blood sugar to see if this happens.<\/li><li>Allopurinol Accord can sometimes affect the blood.&nbsp;Contact your doctor as soon as possible if you notice that you get bruises more easily than usual or if you get a sore throat or other signs of&nbsp;infection.&nbsp;These effects usually occur in people with liver or kidney problems.<\/li><li>Allopurinol Accord may affect the lymph nodes<\/li><li>infertility&nbsp;in men,&nbsp;impotence<\/li><li>breast augmentation, in both men and women<\/li><li>altered bowel movements\/bowel habits<\/li><li>taste changes<\/li><li>cataract<\/li><li>hair loss or discoloration of the hair<\/li><li>Depression<\/li><li>disorders of muscle coordination (&nbsp;ataxia&nbsp;)<\/li><li>creeping, tickling, stinging, burning sensation in the skin (&nbsp;paresthesia&nbsp;).<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Allopurinol Accord<\/h2>\n\n\n\n<p>Keep this medicine out of sight&nbsp;<strong>&#8211;<\/strong>&nbsp;and the sight of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the blister and the carton.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Do not store above 30 \u00b0 C.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is allopurinol.<\/p>\n\n\n\n<p>Allopurinol Accord 100 mg: Each tablet contains 100 mg of allopurinol.<\/p>\n\n\n\n<p>Allopurinol Accord 300 mg: Each tablet contains 300 mg of allopurinol.<br><\/p>\n\n\n\n<p>Other ingredients are:<br><\/p>\n\n\n\n<p>lactose monohydrate;&nbsp;crospovidone, type B;&nbsp;corn starch;&nbsp;povidone K30 and magnesium stearate.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Allopurinol Accord 100 mg are white to off-white, round, biconvex, uncoated tablets, labeled \u201cAW\u201d on one side and no label on the other.&nbsp;Diameter: about 8 mm.<br><\/p>\n\n\n\n<p>Allopurinol Accord 300 mg are white to off-white, round, biconvex, uncoated tablets with a beveled edge, marked with \u201cAX\u201d on one side and no marking on the other side.&nbsp;Diameter: about 11.2 mm.<br><\/p>\n\n\n\n<p>PVC \/ aluminum blisters containing 25, 28, 30, 50, 60, 90 and 100 tablets.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Accord Healthcare BV<\/p>\n\n\n\n<p>Winthontlaan 200<\/p>\n\n\n\n<p>3526 VK Utrecht<\/p>\n\n\n\n<p>Netherlands<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Accord Healthcare Limited<\/p>\n\n\n\n<p>Sage House, 319 Pinner Road<\/p>\n\n\n\n<p>North Harrow, Middlesex, HA1 4HF<\/p>\n\n\n\n<p>UK<br><\/p>\n\n\n\n<p>LABORATORI FUNDACI\u00d3 DAU<\/p>\n\n\n\n<p>C \/ C, 12-14 Pol.&nbsp;Ind.&nbsp;Zona Franca<\/p>\n\n\n\n<p>Barcelona, \u200b\u200b08040&nbsp;<br>Spain<br><\/p>\n\n\n\n<p>Accord Healthcare Polska Sp.&nbsp;z oo<\/p>\n\n\n\n<p>ul.&nbsp;Ta\u015bmowa 7&nbsp;<br>Warszawa 02-677<\/p>\n\n\n\n<p>Poland<br><\/p>\n\n\n\n<p>Accord Healthcare Polska Sp.&nbsp;z oo<\/p>\n\n\n\n<p>ul.&nbsp;Lutomierska 50&nbsp;<br>Pabianice 95-200&nbsp;<br>Poland<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Allopurinol Accord contains the active substance allopurinol. This medicine belongs to a group of medicines called enzyme inhibitors. They work by regulating the speed of certain chemical processes in the body.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[10882,10916,10919,10885,10893,10886,10920,10918,10884,10883,10917],"class_list":["post-5225","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-allopurinol","tag-allopurinol-accord","tag-allopurinol-accord-tablet","tag-allopurinol-tablet","tag-benefit-of-allopurinol","tag-side-effects-of-allopurinol","tag-side-effects-of-allopurinol-accord","tag-what-allopurinol-accord-is-used-for","tag-what-allopurinol-is-used-for","tag-what-is-allopurinol","tag-what-is-allopurinol-accord"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5225","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5225"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5225\/revisions"}],"predecessor-version":[{"id":12846,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5225\/revisions\/12846"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5225"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5225"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5225"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}