{"id":5060,"date":"2020-12-08T11:44:17","date_gmt":"2020-12-08T11:44:17","guid":{"rendered":"https:\/\/zeepedia.com\/?p=5060"},"modified":"2021-08-10T07:39:24","modified_gmt":"2021-08-10T07:39:24","slug":"akineton","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/akineton\/","title":{"rendered":"Akineton &#8211; Biperidenlaktat uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n5 mg \/ ml&nbsp;injection&nbsp;solution&nbsp;<br>biperidenlaktat<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Akineton is and what it is used for<\/h2>\n\n\n\n<p>Akineton is a so-called anticholinergic drug used to&nbsp;treat Parkinson&#8217;s disease.&nbsp;The drug can also be used for so-called extrapyramidal symptoms that have arisen due to other drug use.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using Akineton<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Akineton<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to biperiden lactate or any of the other ingredients of this medicine (listed in section 6).<\/li><li>If you have stone formation (&nbsp;stenosis&nbsp;) of the gastrointestinal tract, the risk of&nbsp;acute&nbsp;glaucoma&nbsp;(&nbsp;glaucoma&nbsp;) or if you suffer from&nbsp;tardive dyskinesia&nbsp;(a delayed movement disorder).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Akineton.<br><\/p>\n\n\n\n<p>Take special care with Akineton if you have an enlarged&nbsp;prostate, an increased risk of cramps and palpitations.<\/p>\n\n\n\n<p>Elderly people may be more sensitive to this type of medicine and the&nbsp;dose&nbsp;may need to be adjusted by a doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Akineton<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Concomitant use of Akineton and other anticholinergic drugs such as&nbsp;neuroleptics(medicines for nervous system diseases),&nbsp;antihistamines&nbsp;(medicines for&nbsp;allergies&nbsp;), antiparkinsonian medicines,&nbsp;antispasmodics&nbsp;(antispasmodics),&nbsp;quinidine&nbsp;(heart medicine), and&nbsp;levodopa&nbsp;(medicines for&nbsp;Parkinson&#8217;s disease&nbsp;) may strengthen&nbsp;side effects&nbsp;of the drugs.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Akineton with alcohol<\/h2>\n\n\n\n<p>You should avoid drinking alcohol during treatment with Akineton.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>Limited experience of use during pregnancy.<br><\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Biperiden passes into breast milk and may affect the breast-feeding baby.&nbsp;Breast-feeding is not recommended when using Akineton.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Akineton may reduce the reactivity of some patients and may therefore affect your ability to drive or use tools or machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Akinetone contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per&nbsp;ampoule, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Akineton<\/h2>\n\n\n\n<p>This medicine is given to you by a doctor or other healthcare professional.<\/p>\n\n\n\n<p>Dose&nbsp;one is determined by the doctor, who adjusts it individually for you.<\/p>\n\n\n\n<p>Older people may need a lower&nbsp;dose.<br><\/p>\n\n\n\n<p>Akinetone 5 mg\/ml&nbsp;solution for injection&nbsp;is injected into a muscle or given slowly&nbsp;intravenously.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Side effects&nbsp;can occur especially at the beginning of treatment and if the&nbsp;dose is increased too quickly.<br><\/p>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dry mouth, nausea, stomach upset<\/li><li>Memory disorders, fatigue, dizziness<\/li><li>Drowsiness<\/li><li>Temporarily reduced&nbsp;REM sleep&nbsp;(&nbsp;sleep&nbsp;phase with rapid eye movements)<\/li><li>High heart rate (&nbsp;tachycardia&nbsp;)<\/li><li>Muscle twitching.<\/li><\/ul>\n\n\n\n<p>In higher&nbsp;doses, the following&nbsp;side effects&nbsp;may occur upset mood, anxiety, fear, confusion, hallucinations, and insomnia.&nbsp;Central stimulant effects are common in patients with symptoms of mental retardation and may require a&nbsp;dose&nbsp;reduction.<br><\/p>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hypersensitivity<\/li><li>Allergic skin rash, reduced sweating<\/li><li>Headache, difficulty controlling movements (&nbsp;dyskinesia&nbsp;), difficulty coordinating movements (&nbsp;ataxia&nbsp;), speech difficulties, increased tendency to seizures<\/li><li>Nervousness,&nbsp;euphoria<\/li><li>Difficulty urinating (especially in patients with an enlarged&nbsp;prostate, dose reduction is recommended), inability to empty the bladder,<\/li><li>Constipation<\/li><li>Slow heart rate (&nbsp;bradycardia&nbsp;), decrease in blood pressure (after&nbsp;intravenous administration)<\/li><li>Inability to adjust the eye to different distances (ackommodationsbesv\u00e4r), enlarged&nbsp;pupils, photophobia,&nbsp;glaucoma&nbsp;(&nbsp;glaucoma&nbsp;).<\/li><\/ul>\n\n\n\n<p><em>No known frequency (cannot be calculated from the available data):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inflammation&nbsp;of the parotid gland (parotitis).<\/li><\/ul>\n\n\n\n<p><em>Reporting of&nbsp;side effects&nbsp;ar<\/em><\/p>\n\n\n\n<p>If you get&nbsp;any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any&nbsp;side effects&nbsp;not mentioned in this information.&nbsp;You can also report&nbsp;side effects directly (see details below).&nbsp;By reporting&nbsp;side effects, you can help increase drug safety information.<br><\/p>\n\n\n\n<p>The Medical Products Agency<\/p>\n\n\n\n<p>Box 26<\/p>\n\n\n\n<p>751 03 Uppsala<\/p>\n\n\n\n<p><br><\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Akineton<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is biperiden lactate.<\/li><li>The other ingredients are sodium lactate (see section 2, \u201cAkinetone contains sodium\u201d) and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Pack sizes: 5&#215;1 ml,&nbsp;glass ampoule<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Laboratorio Farmaceutico SIT, Srl<\/p>\n\n\n\n<p>Via Cavour, 70<\/p>\n\n\n\n<p>27035 Co (PV)<\/p>\n\n\n\n<p>Italy<br><\/p>\n\n\n\n<p><strong><em>Information provided by:<\/em><\/strong><\/p>\n\n\n\n<p>POA Pharma Scandinavia AB<\/p>\n\n\n\n<p>Box 24026<\/p>\n\n\n\n<p>400 22 Gothenburg<br><\/p>\n\n\n\n<p>Tel.&nbsp;031-788 05 99<\/p>\n\n\n\n<p>info@poaab.com<br><\/p>\n\n\n\n<p>This leaflet was last amended on 2018-08-24<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The following information is intended for healthcare professionals only:<\/h2>\n\n\n\n<p><strong><em>Dosage&nbsp;and&nbsp;route of&nbsp;administration<\/em><\/strong><br><\/p>\n\n\n\n<p><em>Parkinsonism:<\/em>&nbsp;In severe cases, 2 (\u20134)&nbsp;ampoules&nbsp;[10 (\u201320) mg]&nbsp;intramuscularly&nbsp;or slowly&nbsp;intravenously, distributed throughout the day.<\/p>\n\n\n\n<p><em>Drug-induced extrapyramidal symptoms<\/em>&nbsp;(&nbsp;acute dystonia&nbsp;and&nbsp;initial&nbsp;dyskinesia&nbsp;):<\/p>\n\n\n\n<p>In&nbsp;acute dystonia, \u00bd \u2013 1&nbsp;ampoule&nbsp;(2.5\u20135 mg) is&nbsp;given intramuscularly&nbsp;or slowly&nbsp;intravenously.&nbsp;The extrapyramidal symptoms may disappear already during&nbsp;injection one.&nbsp;In these cases, the&nbsp;injection&nbsp;should be&nbsp;stopped.&nbsp;If necessary, the prescribed&nbsp;dose can&nbsp;be given again after 30 minutes.<\/p>\n\n\n\n<p><strong><em>Incompatibilities<\/em><\/strong><\/p>\n\n\n\n<p>The solution for injection should not be mixed with other medicines, as miscibility studies are not available<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Akineton is a so-called anticholinergic drug used to treat Parkinson&#8217;s disease. The drug can also be used for so-called extrapyramidal symptoms that have arisen due to other drug use.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[11292,11295,11287,11290,11296,11291,11294,11289,11293,11288],"class_list":["post-5060","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-akineton","tag-akineton-injection","tag-biperidenlaktat","tag-biperidenlaktat-injection","tag-side-effects-of-akineton","tag-side-effects-of-biperidenlaktat","tag-what-akineton-is-used-for","tag-what-biperidenlaktat-is-used-for","tag-what-is-akineton","tag-what-is-biperidenlaktat"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5060","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=5060"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5060\/revisions"}],"predecessor-version":[{"id":13006,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/5060\/revisions\/13006"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=5060"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=5060"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=5060"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}