{"id":4954,"date":"2020-12-04T09:40:25","date_gmt":"2020-12-04T09:40:25","guid":{"rendered":"https:\/\/zeepedia.com\/?p=4954"},"modified":"2023-02-14T05:25:35","modified_gmt":"2023-02-14T05:25:35","slug":"aethoxysklerol","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/aethoxysklerol\/","title":{"rendered":"Aethoxysklerol &#8211; Lauromacrogol 400 Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p><strong>Aethoxysklerol Solution for injection 5 mg\/ml&nbsp;(colorless, clear)<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Is Aethoxysclerol, And What Aethoxysklerol Is Used For<\/h2>\n\n\n\n<p>Aethoxysclerol contains the active substance Lauromacrogol 400, which causes controlled\u00a0inflammation\u00a0and is used for therapeutic purposes.\u00a0Aethoxysclerol is injected into the blood vessel to be treated and affects the inside so that after\u00a0inflammation, it\u00a0heals and blood no longer flows through the\u00a0vessel.\u00a0The whole process takes about four weeks.\u00a0Aethoxysclerol also has a local anesthetic effect.<\/p>\n\n\n\n<p>Aethoxysclerol is used to treat:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Varicose veins (telangiectasia)<\/li><li>Varicose veins (varices)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/hemorrhoids\/\">Hemorrhoids<\/a><\/li><li>Bleeding from the stomach \/ small intestine or esophageal hernia<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before You Are Given Aethoxysclerol:<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Aethoxycyclerol Should Not Be Given To You:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to Aethoxysklerol 400 injection  or any other ingredients of Aethoxysklerol (listed in section 6).<\/li><\/ul>\n\n\n\n<p><strong>Varicose veins \/ Varicose veins<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you suffer from brittle skin (skin\u00a0atrophy\u00a0)<\/li><li>Infectious skin diseases or skin diseases with a risk of blood poisoning<\/li><li>If you have\u00a0edema\u00a0(swelling) due to\u00a0decreased blood flow in veins (blood vessels that carry blood to the heart)<\/li><li>If you have\u00a0diabetes,\u00a0impaired blood flow in the small\u00a0arteries\u00a0are (blood vessels that carry blood from the heart)<\/li><li>State with reduced blood flow in the\u00a0artery\u00a0was<\/li><li>If you are bedridden<\/li><li>If you have a blood clot (\u00a0thrombosis\u00a0) or an increased risk of getting blood clots<\/li><li>If you have had superficial blood clots then a month of symptom relief must pass before new treatment for varicose veins can be given<\/li><li>If you have a right-left\u00a0shunt\u00a0(heart malformation where oxygen-poor blood is sent out into the body) that causes symptoms and needs to be treated with foamed Aethoxysclerol (foam sclerotherapy)<\/li><\/ul>\n\n\n\n<p><strong>Hemorrhoids<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have an\u00a0acute\u00a0inflammation\u00a0of the rectum<\/li><\/ul>\n\n\n\n<p><strong>Bleeding from the stomach \/ small intestine or esophageal hernia<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have impaired pumping capacity from the heart (\u00a0heart failure\u00a0)<\/li><li>If\u00a0ECG\u00a0(\u00a0electrocardiogram\u00a0) indicates that you affect your heart rate (\u00a0AV block\u00a0)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor\/nurse before giving Aethoxysclerol if you have or have had any of the following:<\/p>\n\n\n\n<p><strong>Varicose veins \/ Varicose veins<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Heart failure<\/li><li>Atherosclerosis with high\u00a0blood pressure<\/li><li>Asthma<\/li><li>Liver or kidney disease<\/li><li>Right-left\u00a0shunt\u00a0(heart malformation where oxygen-poor blood is sent out into the body) without symptoms and should undergo treatment with foamed Aethoxysclerol (foam sclerotherapy)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/visual-impairment\/\">Visual impairment<\/a>, mental symptoms, or disorders of the nervous system after previous treatment with foamed Aethoxysclerol (foam sclerotherapy)<\/li><\/ul>\n\n\n\n<p><strong>Hemorrhoids<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">Fever<\/a><\/li><\/ul>\n\n\n\n<p><strong>Bleeding from the stomach \/ small intestine or esophageal hernia<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Heart failure<\/li><li>Kidney disease<\/li><li>Asthma<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Aethoxysclerol<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Aethoxysclerol has a weak blood-thinning effect and may therefore be unsuitable for you if you are being treated with blood thinners.<\/p>\n\n\n\n<p>Aethoxysclerol also has a local anesthetic effect.\u00a0When combined with anesthetics, there is therefore a risk of an increased effect on the cardiovascular system.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding, And Fertility<\/h2>\n\n\n\n<p>Tell your doctor if you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby before taking Aethoxysklerol. Experience from the treatment of pregnant women is lacking. There is no information on whether Aethoxysclerol passes into breast milk.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>Aethoxysclerol has no known effect on the ability to drive or use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Aethoxysclerol Contains Excipients<\/h2>\n\n\n\n<p>Aethoxycyclerol contains 5% (v \/ v)&nbsp;ethanol&nbsp;(alcohol), i.e.&nbsp;42 mg per ml, equivalent to 1 ml strong beer or 0.42 ml wine.&nbsp;Harmful to those suffering from alcoholism.&nbsp;Should be considered in the treatment of pregnant or lactating women, children, and high-risk patients such as patients with liver disease or&nbsp;epilepsy.<\/p>\n\n\n\n<p>Aethoxysclerol contains\u00a0potassium\u00a0, but less than 0.5 mmol (19.5 mg) per\u00a0ampoule\u00a0, ie\u00a0is next to &#8220;potassium free&#8221;. Aethoxysclerol contains\u00a0sodium\u00a0, but less than 0.5 mmol (11.5 mg) per\u00a0ampoule\u00a0, ie\u00a0is next to &#8220;sodium free&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How Aethoxysclerol Is Given:<\/h2>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Aethoxysklerol uses:<\/span><\/strong><\/p>\n\n\n\n<p>Aethoxysclerol is given to you as an\u00a0injection\u00a0in solution or foamed with air.\u00a0aethoxysklerol injection is\u00a0placed adjacent to the blood vessel to be treated.\u00a0One or more\u00a0injections\u00a0are given at the same time.\u00a0For each disease condition to be treated, a special Aethoxysklerol injection technique and subsequent treatment are used.<\/p>\n\n\n\n<p>If you have any further questions about the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Aethoxysklerol Side Effects<\/h2>\n\n\n\n<p>Like all medicines, Aethoxysklerol can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Serious&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>If you think you have a serious side effect, contact your doctor immediately.\u00a0Symptoms of these\u00a0side effects\u00a0are described below:<\/p>\n\n\n\n<p><strong>Varicose veins.&nbsp;Varicose veins.<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swelling of the face, tongue, or throat, difficulty swallowing,\u00a0hives,\u00a0and difficulty breathing.\u00a0These symptoms may be signs of\u00a0an anaphylactic reaction, shock, or angioedema, which have been reported as rare\u00a0side effects\u00a0(may affect up to 1 in 10,000 people).<\/li><li>Severe and sudden bone swelling.\u00a0This may be a sign of a blood clot in a deep vein, which has been reported as a rare side effect (may affect up to 1 in 1,000 people).<\/li><li>Chest <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a> and difficulty breathing.\u00a0This may be a sign of a blood clot in the lung, which has been reported as a rare side effect (may affect up to 1 in 10,000 people).\u00a0Chest pain may also be a sign of pre-myocardial infarction, which has been reported (occurring in an unknown number of users).<\/li><li>A sudden impact on consciousness, speech, or balance.\u00a0This can be a sign of a stroke, which has been reported as a rare side effect (may affect up to 1 in 10,000 people).<\/li><\/ul>\n\n\n\n<p><strong>Bleeding from the stomach \/ small intestine.<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pain from the abdomen.\u00a0This may be a sign of tissue death, as reported (it occurs in an unknown number of users).<\/li><\/ul>\n\n\n\n<p><strong>Matstrups\u00e5derbr\u00e5ck.<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pain from the neck down to the abdomen.\u00a0This may be a sign of tissue death\u00a0and perforation\u00a0of the esophageal wall, which has been reported as a less common side effect (may affect up to 1 in 100 people).<\/li><\/ul>\n\n\n\n<p><strong>Other\u00a0side effects\u00a0<\/strong>Aethoxysklerol side effects are:<\/p>\n\n\n\n<p><strong>Varicose veins.&nbsp;Varicose veins.<\/strong><\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people)<\/em>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hemorrhage<\/li><li>Vascular regeneration<\/li><li>Pigmentation\u00a0of the skin adjacent to the treated blood vessel<\/li><\/ul>\n\n\n\n<p>Aethoxysklerol injection site pain (short-term), blood clot at the injection site.<\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people)<\/em>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inflammation\u00a0of blood vessels near the treated\u00a0vessel<\/li><li>Simultaneously with\u00a0inflammation, blood clots can also occur<\/li><li>Skin reactions include:<ul><li>Hives\u00a0or blisters<\/li><li>Allergic\u00a0inflammation<\/li><li>Redness<\/li><li>Itching<\/li><li>Eczema<\/li><li>Swelling<\/li><li>Damaged skin (tissue death)<\/li><li>Skin hardening or decreased sensation in the skin (nerve damage) at the Aethoxysklerol injection site.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people)<\/em>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pain in the legs<\/li><\/ul>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 people)<\/em>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Asthma<\/li><li>Hives\u00a0(all over the body)<\/li><li>Headache<\/li><li>Migraine<\/li><li>Confusion<\/li><li>Loss of consciousness<\/li><li>Dizziness<\/li><li>Palpitations<\/li><li>Fainting<\/li><li>Shortness of breath<\/li><li>Chest discomfort<\/li><li>Visual disturbances (short-term)<\/li><li>Taste disturbances<\/li><li>Nausea<\/li><li>Fever<\/li><li>Flushing<\/li><li>Weakness<\/li><li>Malaise<\/li><li>Abnormal\u00a0blood pressure<\/li><li>Sensory disturbances<\/li><li>Increased hair growth in the area being treated<\/li><\/ul>\n\n\n\n<p><strong>Hemorrhoids.<\/strong><\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people)<\/em>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pressure\/pain from the injection site.<\/li><\/ul>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people)<\/em>: <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>In association with treated hemorrhoids:<ul><li>Minor bleeding<\/li><li>Minor tissue death<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>Bleeding from the stomach \/ small intestine.<\/strong><\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people)<\/em>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Increase in size of existing\u00a0stomach ulcer.<\/li><\/ul>\n\n\n\n<p><strong>Matstrups\u00e5derbr\u00e5ck.<\/strong><\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10<\/em>\u00a0people\u00a0<em>)<\/em>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pulmonary embolism<\/li><li>Ulceration<\/li><li>Esophageal stricture<\/li><li>Fever<\/li><\/ul>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people)<\/em>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Bleeding after sclerosis<\/li><li>Varicose veins<\/li><\/ul>\n\n\n\n<p><em>Has been reported (occurs in an unknown number of users)<\/em>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cases of\u00a0heart failure after overdose<\/li><li>Pneumonia\u00a0after inhalation of foreign matter<\/li><\/ul>\n\n\n\n<p><strong>Reporting of\u00a0side effects\u00a0are<\/strong><\/p>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse if you get any side effects.\u00a0This also applies to\u00a0side effects\u00a0that are not mentioned in this information.\u00a0You can also report\u00a0side effects\u00a0directly (see details below).\u00a0By reporting\u00a0side effects, you can help increase the safety of medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Aethoxysclerol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep Aethoxysklerol out of sight and reach of children.<\/li><li>No special storage instructions.<\/li><li>Do not use Aethoxysklerol\u00a0after the expiry date, which is stated on the\u00a0ampoule\u00a0and the outer carton.\u00a0The expiration date is the last day of the specified month.<\/li><li>Thiaethoxysklerol is for single use only.\u00a0The remaining solution should be discarded.<\/li><li>Medicines should not be disposed of via wastewater.\u00a0Ask your pharmacist how to dispose of medicines that are no longer required.\u00a0These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other information oF Aethoxysklerol Injection<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is aethoxysklerol 400 injection.<\/li><li>One ml Aethoxysclerol 5 mg \/ ml contains 5 mg lauromacrogol 400<\/li><li>One ml Aethoxysclerol 10 mg \/ ml contains 10 mg lauromacrogol 400<\/li><li>One ml of Aethoxysclerol 30 mg\/ml contains 30 mg of lauromacrogol 400<\/li><li>The other ingredients are\u00a096%\u00a0ethanol, potassium dihydrogen phosphate, disodium phosphate dihydrate, and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><em>5 mg\/ml\u00a0solution for injection<\/em><\/li><li>Ampoule\u00a0(glass): 5 \u00d7 2 ml.<\/li><li><em>10 mg\/ml<\/em>\u00a0solution for injection<\/li><li>Ampoule\u00a0(glass): 5 \u00d7 2 ml<\/li><li>30 mg\/ml\u00a0solution for injection<\/li><li>Ampoule\u00a0(glass): 5 \u00d7 2 ml.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>Chemische Fabrik Kreussler &amp; Co GmbH<\/p>\n\n\n\n<p>PO Box 120454<\/p>\n\n\n\n<p>D-65203 Wiesbaden, Germany<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about Aethoxysklerol:<\/p>\n\n\n\n<p>Inverdia AB<\/p>\n\n\n\n<p>Ekbacksv.&nbsp;20<\/p>\n\n\n\n<p>S-16869 Bromma<\/p>\n\n\n\n<p>Tel: +4686275044<\/p>\n\n\n\n<p>info@inverdia.com<\/p>\n\n\n\n<p>This leaflet was last modified on 2 February 2019<\/p>\n\n\n\n<p>The Medical Products Agency<\/p>\n\n\n\n<p>Box 26,<\/p>\n\n\n\n<p>751 03 Uppsala;<\/p>\n\n\n\n<p>website: www.lakemedelsverket.se<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The Following Information Is Intended For Healthcare Professionals Only:<\/h2>\n\n\n\n<p><strong>Dosage&nbsp;and&nbsp;route of&nbsp;administration<\/strong><\/p>\n\n\n\n<p>Teleangiectasias and varices.<\/p>\n\n\n\n<p><strong>Aethoxysklerol Dosage:<\/strong><\/p>\n\n\n\n<p>The daily dose of Aethoxysklerol should not exceed 2 mg\/kg body weight.\u00a0When using a foamed solution, it is recommended not to exceed 10 ml of\u00a0foam\u00a0per treatment session and day, regardless of the strength of Aethoxysclerol and the patient&#8217;s weight.<\/p>\n\n\n\n<p><strong>Aethoxysklerol injection techniques:<\/strong><\/p>\n\n\n\n<p>Below is a brief description of the Aethoxysklerol injection technique for the various sub-indications.\u00a0However, it is recommended that practical knowledge be gained about the various injection techniques before starting patient treatment.<\/p>\n\n\n\n<p><strong>Telangiectasia (Aethoxysclerol 5 mg\/ml):<\/strong><\/p>\n\n\n\n<p>Intravascularly injected for vascular whitening, usually &lt;0.5 ml;\u00a0a total of 2-4 ml at a time.\u00a0Perivasally, 0.05-0.1 ml is injected into the\u00a0dermis\u00a0at 1 cm intervals;\u00a03-4\u00a0injections\u00a0of 0.05 ml at the first opportunity, then about 10\u00a0injections\u00a0of 0.05-0.1 ml at normal tolerance.<\/p>\n\n\n\n<p>Local compression of treated\u00a0vessels is\u00a0recommended to facilitate healing.\u00a0After the treatment, the\u00a0vessel\u00a0turns\u00a0red, sometimes blue, to slowly disappear for about 3 weeks.<\/p>\n\n\n\n<p><strong>Reticular varices (Aethoxysclerol 10 mg\/ml).<\/strong><\/p>\n\n\n\n<p><strong>Solution:<\/strong><\/p>\n\n\n\n<p>Intravascularly injected 0.1-0.5 ml per puncture.\u00a0Adequate\u00a0interaction\u00a0with the\u00a0endothelium of the\u00a0venous segment\u00a0in the puncture area is sought.<\/p>\n\n\n\n<p><strong>Small varices (Aethoxysclerol 10 mg\/ml):<\/strong><\/p>\n\n\n\n<p><strong>Solution:<\/strong><\/p>\n\n\n\n<p>Intravasally, 0.1-1.0 ml is injected per puncture.\u00a0Adequate\u00a0interaction\u00a0with the\u00a0endothelium of the\u00a0venous segment\u00a0in the puncture area is sought.<\/p>\n\n\n\n<p><strong>Foam preparation:<\/strong><\/p>\n\n\n\n<p>Foam preparation of Aethoxysclerol 10 mg\/ml is suitable for treating e.g.\u00a0branches to v. safena Magna.\u00a0For the production of foam, preparation sees under Medium and large varices. As a rule, the venous segment is punctured distally, and the injection volume is determined by the amount necessary for\u00a0adequate\u00a0interaction with the\u00a0endothelium.\u00a0The total volume per\u00a0injection\u00a0should not exceed 6 ml.<\/p>\n\n\n\n<p>Medium and large varices (Aethoxysclerol 30 mg\/ml).<\/p>\n\n\n\n<p><strong>Solution:<\/strong><\/p>\n\n\n\n<p>Each\u00a0varix is\u00a0injected with 0.2-2 ml.\u00a0Several varices are often treated at the same time.\u00a0To assess individual response, only two varices should be injected for the first time, with a maximum of 1 ml per\u00a0varix.<\/p>\n\n\n\n<p><strong>Foam preparation:<\/strong><\/p>\n\n\n\n<p>The foam preparation is suitable for treating large varicose veins, e.g.\u00a0varices on v. safena Magna, v. safena Parva, and large branches to these.<\/p>\n\n\n\n<p>EasyFoam Kit should be used to produce a standardized, homogeneous, fine-bubble, and viscous microfoam (see below).\u00a0With the EasyFoam Kit, the ratio of sclerosant to air is 1+ 4.6 (1.6 ml Aethoxysclerol is mixed with 7.4 ml air).<\/p>\n\n\n\n<p>The recommended volume of foam preparation per treatment session is 2-8 ml;\u00a0the maximum volume &#8211; regardless of the patient&#8217;s weight &#8211; per treatment session (for one or more\u00a0injections\u00a0) is 10 ml.\u00a0One foam can be administered via injection cannula at one or more sites or via a\u00a0catheter.<\/p>\n\n\n\n<p>Puncture is usually made distal to the varicose veins segment but not closer to the entrance of the femoral vein in the femoral vein than 8-10 cm.\u00a0Recommended volumes per puncture are up to 6 ml\u00a0foam\u00a0for v.<\/p>\n\n\n\n<p>Safena Magna and up to 4 ml\u00a0foam\u00a0for v. Safena Parva;\u00a0the total volume injected is determined by the amount necessary to\u00a0adequately\u00a0fill the treated vein segment, determined by ultrasound.\u00a0However, the maximum daily dose (2 mg\/kg body weight) of Aethoxysklerol 30 mg\/ml must not be exceeded.\u00a0Foam sclerotherapy of invisible veins should be performed under ultrasound guidance (preferably of the duplex type).<\/p>\n\n\n\n<p>Short, visible segments of varicose veins can be injected without ultrasound;\u00a0the injection volume is determined by the amount required for adequate\u00a0interaction with\u00a0endothelium,\u00a0et.\u00a0Upon\u00a0foam injection, the cannula should not be less than 25 G. Regardless of venipuncture, and the\u00a0injection\u00a0s performed only on one leg in horizontal or pupil guest mode.<\/p>\n\n\n\n<p>After\u00a0administration\u00a0one, to support a slow flow of\u00a0foam\u00a0from the treated bone, it is recommended that the bone be kept elevated for 5 minutes and that the patient be completely still;\u00a0Waltz maneuvering or other muscular activity should also be avoided.<\/p>\n\n\n\n<p>If immediately after the treatment, during an ultrasound check, a foam accumulation is found in the deep vein system, muscle activation, e.g.\u00a0dorsiflexion with the ankle, is performed by the patient.<\/p>\n\n\n\n<p><strong>General in\u00a0sclerotherapy\u00a0of telangiectasia \/ varices:<\/strong><\/p>\n\n\n\n<p>In the presence of several areas with telangiectasias or varices, it is advantageous that the treatment is performed on several occasions to get good control of the treatment effect, which gives the best medical and aesthetic results.<\/p>\n\n\n\n<p>Compression of treated areas results in better healing of\u00a0vessels\u00a0and a lesser degree of unwanted\u00a0phlebitis\u00a0and hemosiderin storage in the skin in connection with treated\u00a0vessels.\u00a0Repeated treatment may be necessary on return visits, and any\u00a0clots, which sometimes form, can be removed if necessary, e.g.\u00a0by incision and then expression.\u00a0These measures reduce pain and skin pigmentation.<\/p>\n\n\n\n<p><strong>Hemorrhoids\u00a0(Aethoxysclerol 30 mg\/ml):<\/strong><\/p>\n\n\n\n<p>Monotherapy:\u00a0Initially\u00a00.5 ml per grade I and II hemorrhoids.\u00a0At subsequent treatment, 0.5-1 ml per grade I <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/hemorrhoids\/\">hemorrhoid<\/a> and 0.5-1.5 ml per grade II hemorrhoid are given.\u00a0The maximum total dose per treatment session is 2.5 ml.\u00a0The Aethoxysklerol injection\u00a0is placed submucosal immediately above the origin of hemorrhoid.\u00a0Within a week, symptoms of\u00a0hemorrhoids subside\u00a0(bleeding, prolapse) and proctoscopy should then show regenerated\u00a0hemorrhoids.<\/p>\n\n\n\n<p>Combination therapy\u00a0with ligation: Per ligated hemorrhoid 0.3 ml.\u00a0Maximum total dose as above.\u00a0After ligation,\u00a0injection is\u00a0placed\u00a0proximal to the ligature and submucosal in the base of the hemorrhoid.\u00a0Treatment control is with ligation only.<\/p>\n\n\n\n<p><strong>Gastroduodenal\u00a0lesion\u00a0(Aethoxysclerol 10 mg \/ ml):<\/strong><\/p>\n\n\n\n<p>Inject\u00a00.5-2 ml into each quadrant around bleeding\u00a0vessels, non-bleeding\u00a0vessels, leaking bleeding sources, or coagulums.\u00a0The injection\u00a0should be placed near the source of bleeding and cause swelling of the mucous membrane that compresses the source of bleeding.\u00a0Intravascular\u00a0injections\u00a0should not be performed due to the risk of necrosis.<\/p>\n\n\n\n<p>The local maximum\u00a0dose\u00a0per treatment and 24 hours are 15 ml.\u00a0The maximum daily dose is 4 mg\/kg body weight.<\/p>\n\n\n\n<p><strong>Esophageal\u00a0varices (Aethoxysclerol 10 mg\/ml):<\/strong><\/p>\n\n\n\n<p>Two or more\u00a0injections\u00a0of 0.5-1 ml paravaricost, followed by 3-5 ml intravaricost per\u00a0varix\u00a0or\u00a0only 3-5 ml intravaricost per\u00a0varix\u00a0using, for example, the so-called outer tube.\u00a0The maximum daily dose is 4 mg\/kg body weight.\u00a0At least 6 days should pass between repeated treatments.\u00a0A series of treatments should continue until the varicose veins are covered with\u00a0fibrotic\u00a0tissue\u00a0or obliterated;\u00a0usually, at least 3 treatments.<\/p>\n\n\n\n<p><strong>Preparation of Aethoxycyclerol in foam preparation<\/strong>:<\/p>\n\n\n\n<p>EasyFoam Kit should be used to produce a standardized, homogeneous, fine-bubble, and viscous microfoam.\u00a0The EasyFoam Kit contains two syringes, a smaller one in which 1.6 ml of Aethoxysclerol is drawn up and a larger one pre-filled with 7.4 ml of\u00a0sterile\u00a0air.\u00a0The entire contents of the EasyFoam Kit are pumped from one\u00a0syringe\u00a0to the other 20 times without interruption and within about 10 seconds.\u00a0The microfoam is of the desired quality if there are no visible bubbles and no unmixed solution or air.<\/p>\n\n\n\n<p><strong>Warnings<\/strong>:<\/p>\n\n\n\n<p>If Aethoxysclerol is accidentally splashed in the eyes, wash your eyes with water.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Aethoxysklerol is recommended for the sclerotherapy of varicose veins in the lower limbs. The kind and size of the varicose veins that must treat dictate the Aethoxysklerol concentration needed.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[11442,11445,11446,11440,11436,11439,11447,11441,11444,11443,11437,11438],"class_list":["post-4954","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-aethoxysklerol","tag-aethoxysklerol-injection","tag-benefits-of-aethoxysklerol","tag-benefits-of-lauromacrogol-400","tag-lauromacrogol-400","tag-lauromacrogol-400-injection","tag-side-effects-of-aethoxysklerol","tag-side-effects-of-lauromacrogol-400","tag-what-aethoxysklerol-is-used-for","tag-what-is-aethoxysklerol","tag-what-is-lauromacrogol-400","tag-what-lauromacrogol-400-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4954","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=4954"}],"version-history":[{"count":64,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4954\/revisions"}],"predecessor-version":[{"id":48597,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4954\/revisions\/48597"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=4954"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=4954"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=4954"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}