1 mg \/ ml injection solution
Adrenaline<\/p>\n\n\n\n
Adrenaline belongs to a group of drugs called sympathomimetics. Adrenaline is used as a treatment in acute cases of severe allergic reactions.<\/p>\n\n\n\n
Adrenaline contained in Adrenaline Ethypharm may also be approved for the treatment of other conditions not mentioned in this product information. Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n
Talk to your doctor, pharmacist, or nurse before receiving Adrenaline Ethypharm if:<\/p>\n\n\n\n
Talk to your doctor before receiving this medicine if any of these apply to you.<\/p>\n\n\n\n
Tell your doctor or nurse if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n
A large number of drugs can affect the effect of Adrenaline Ethypharm. These medicines include:<\/p>\n\n\n\n
If you are already taking any of these medicines, talk to your doctor before taking Adrenaline Ethypharm.<\/p>\n\n\n\n
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n
Adrenaline should only be used during pregnancy and breastfeeding when doctors consider it absolutely necessary.<\/p>\n\n\n\n
You should not drive or use machines if you are affected by the administration of Adrenaline Ethypharm.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
This medicine contains sodium metabisulphite which may cause allergic reactions<\/p>\n\n\n\n
( hypersensitivity reactions ) which may lead to difficulty breathing or collapse in some individuals. Individuals who have previously had asthma or allergies are more likely to experience these problems.
<\/p>\n\n\n\n
This medicine contains less than 1 mmol sodium (23 mg) per ml, ie essentially ‘sodium-free’.<\/p>\n\n\n\n
You will receive Adrenaline Ethypharm injected into a muscle ( intramuscularly – im) but may also in some cases be injected diluted into a vein ( intravenous -iv).
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Adrenaline should NOT be injected in areas such as fingers, toes, ears, nose, genitals, or tail as blood flow in these areas may become insufficient. If repeated injections required, your doctor will change the injection site. Adrenaline will be given by trained healthcare professionals. The doctor decides what dose and in what way the medicine should be given depending on what is most appropriate in your particular case based on your age and your general condition.<\/p>\n\n\n\n
Adults<\/strong><\/p>\n\n\n\n The most common dose is 0.5 ml. If necessary, this dose can be repeated several times at 5-minute intervals<\/p>\n\n\n\n Older<\/strong><\/p>\n\n\n\n No specific dosing information available for injection of adrenaline in the elderly. However, adrenaline should be used with great caution in these patients.<\/p>\n\n\n\n The following dosage of Adrenaline Ethypharm is recommended:<\/p>\n\n\n\n If necessary, these doses can be repeated several times at 5-15 minute intervals, depending on blood pressure, heart rate, and respiratory function.<\/p>\n\n\n\n A small volume of the syringe should be used.<\/p>\n\n\n\n As an injection is given when you are in hospital, it is unlikely that you have received too little or too much medicine, contact a doctor or nurse if you feel worried.<\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them.<\/p>\n\n\n\n If you get any of the following side effects, stop taking this medicine and contact your doctor immediately:<\/strong><\/p>\n\n\n\n The following side effects have also been reported (affects an unknown number of users):<\/strong><\/p>\n\n\n\n Adrenaline may increase stiffness and tremor ( tremor ) in patients with Parkinson’s syndrome.<\/p>\n\n\n\n Reporting of side effects ar<\/strong><\/p>\n\n\n\n If you get any side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this information. You can also report side effects directly (see details below). By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n The Medical Products Agency<\/p>\n\n\n\n Box 26<\/p>\n\n\n\n 751 03 Uppsala<\/p>\n\n\n\n www.lakemedelsverket.se<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children. Your doctor or nurse will check that the expiry date stated on the label has not expired before you receive Adrenaline Ethypharm. The expiration date is the last day of the specified month. Keep the vial are in the outer carton. Sensitive to light. Do not store above 25 \u00b0 C and do not freeze. You should not receive Adrenaline Ethypharm if you notice that it has already been used or if it appears to have been damaged. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Hydrochloric acid or sodium hydroxide may be added to adjust the acid content ( pH).<\/p>\n\n\n\n Adrenaline Ehtypharm is a clear, colorless solution, whose packs of 10 glass ampoules contain 0.5, 1, 2, 5, or 10 ml each.<\/p>\n\n\n\n Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n Ethypharm<\/p>\n\n\n\n 194 Bureaux de la Colline<\/p>\n\n\n\n Saint- Cloud CEDEX<\/p>\n\n\n\n France Manufacturer<\/strong><\/p>\n\n\n\n Macarthys Laboratories Limited,<\/p>\n\n\n\n Bampton Road,<\/p>\n\n\n\n Harold Hill,<\/p>\n\n\n\n Romford,<\/p>\n\n\n\n Essex, RM38UG<\/p>\n\n\n\n UK This leaflet was last modified on 5 April 2019<\/p>\n\n\n\n For any information about this medicine, please contact the local representative of the Marketing Authorization Holder:<\/strong><\/p>\n\n\n\n Unimedic Pharma AB<\/p>\n\n\n\n medinfo@unimedicpharma.se<\/p>\n\n\n\n + 46 (0) 10-130 99 50<\/p>\n\n\n\n Preparation and handling<\/em><\/p>\n\n\n\n Do not use Adrenaline Ethypharm 1 mg\/ml solution for injection if you notice that it is discolored.<\/p>\n\n\n\n Repeated topical administration may cause necrosis at the injection site. The best site for intramuscular injection is anterolateral in the middle third of the thigh. The needle used for injection must be long enough to ensure that the adrenaline reaches the muscle.<\/p>\n\n\n\n Intramuscular injection in fingers, toes, ears, nose, genitals, or tail should be avoided due to the risk of tissue necrosis.<\/p>\n\n\n\n Prolonged administration may cause metabolic acidosis, renal necrosis, or tachyphylaxis.<\/p>\n\n\n\n The use of adrenaline should be avoided or avoided with extreme caution in patients under anesthesia with halothane or other halogenated anesthetics, due to the risk of causing ventricular fibrillation.<\/p>\n\n\n\n Do not mix with other drugs unless compatibility has been confirmed. Adrenaline should not be used during the expulsion phase of labor. Accidental intravascular injection may result in cerebral hemorrhage due to the sudden rise in blood pressure.<\/p>\n\n\n\n Start monitoring the patient as soon as possible (heart rate, blood pressure, ECG, pulse oximetry) to assess the response to adrenaline.<\/p>\n\n\n\n Incompatibilities<\/em><\/p>\n\n\n\n Adrenaline is rapidly denatured by oxidizing agents and alkalis including sodium bicarbonate, halogens, nitrates, nitrites, and salts of iron, copper, and zinc.<\/p>\n\n\n\n Dosage and route of administration<\/em><\/p>\n\n\n\n Adrenaline Ethypharm 1 mg\/ml solution for injection is intended for intramuscular administration.<\/p>\n\n\n\n Administering not adrenaline Ethypharm 1 mg\/ml injection solution intravenously.<\/strong><\/p>\n\n\n\n Intravenous administration of adrenaline for the treatment of anaphylaxis requires an adrenaline solution of 0.1 mg\/ml.<\/strong><\/p>\n\n\n\n Intramuscular administration is generally preferred in the initial treatment of anaphylaxis and intravenous administration is generally more appropriate in intensive care units or emergency rooms. Adrenaline Ethypharm 1 mg\/ml solution for injection is not suitable for intravenous administration. If Adrenaline 0.1 mg \/ ml is not available, Adrenaline Ethypharm 1 mg \/ ml solution for injection should be diluted to 0.1 mg \/ ml solution (ie a 1:10 dilution) before administration . Intravenous administration of adrenaline should be done with great caution and by specialists with experience of intravenous use of adrenaline. Acute anaphylaxis<\/em><\/p>\n\n\n\n The intramuscular route of administration is preferred for most individuals requiring treatment with adrenaline for acute anaphylaxis. The most common dose for adults is 0.5 mg (0.5 ml adrenaline 1 mg \/ ml). If necessary, this dose can be repeated several times at 5-minute intervals, depending on blood pressure, heart rate, and respiratory function. Older:<\/p>\n\n\n\n No specific dosing information available for injection of adrenaline in the elderly. However, adrenaline should be used with great caution in these patients, as they may be more susceptible to cardiovascular side effects from adrenaline.<\/p>\n\n\n\n Pediatric population<\/strong><\/p>\n\n\n\n The following dosage of Adrenaline Ethypharm is recommended:<\/p>\n\n\n\n If necessary, these doses can be repeated several times at 5-15 minute intervals, depending on blood pressure, heart rate, and respiratory function.<\/p>\n\n\n\n A small volume of the syringe should be used.<\/p>\n\n\n\n Disposal<\/em><\/p>\n\n\n\n Any unused product or waste material should be disposed of in accordance with local requirements. Overdose<\/em><\/p>\n\n\n\n Sign<\/p>\n\n\n\n Overdose of Adrenaline Ethypharm may cause severe hypertension. It can result in cerebral, cardiovascular, or vascular effects, which can be fatal (cerebral hemorrhage, dysrhythmias such as transient bradycardia followed by tachycardia which may lead to arrhythmia, myocardial necrosis, acute pulmonary edema, renal failure ). Treatment<\/em><\/p>\n\n\n\n The effects of adrenaline can be counteracted, depending on the patient’s condition, by administering fast-acting vasodilators, fast-acting alpha-receptor blockers (eg phentolamine), or beta-blockers, e.g. propranolol. Due to the short half-life of adrenaline, treatment with these drugs may not be necessary. If prolonged hypotension occurs, administration of an additional vasodilator such as norepinephrine may be required.<\/p>\n","protected":false},"excerpt":{"rendered":" Adrenaline belongs to a group of drugs called sympathomimetics. Adrenaline is used as a treatment in acute cases of severe allergic reactions.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[4044,11545,11548,11549,4471,4046,11525,11550,11547,11524,4045,11546],"class_list":["post-4844","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-adrenaline","tag-adrenaline-ethypharm","tag-adrenaline-ethypharm-injection","tag-adrenaline-ethypharm-side-effects","tag-adrenaline-injection","tag-adrenaline-side-effects","tag-benefits-of-adrenaline","tag-benefits-of-adrenaline-ethypharm","tag-what-adrenaline-ethypharm-is-used-for","tag-what-adrenaline-is-used-for","tag-what-is-adrenaline","tag-what-is-adrenaline-ethypharm"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4844","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=4844"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4844\/revisions"}],"predecessor-version":[{"id":13087,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4844\/revisions\/13087"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=4844"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=4844"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=4844"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Use for children and adolescents<\/h2>\n\n\n\n
Age<\/strong><\/td> Dose<\/strong><\/td><\/tr> Over 12 years<\/td> 0.5 mg im (0.5 ml 1 mg \/ ml solution for injection )0.3 mg im (0.3 ml 1 mg \/ ml solution for injection ) if the child is small or pre-pubertal<\/td><\/tr> 6-12 years<\/td> 0.3 mg im (0.3 ml 1 mg \/ ml solution for injection )<\/td><\/tr> 6 months – 6 years<\/td> 0.15 mg im (0.15 ml 1 mg \/ ml solution for injection )<\/td><\/tr> For 6 months<\/td> 0.01 mg \/ kg im (0.01 ml \/ kg 1 mg \/ ml solution for injection )<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n If you use more Adrenaline Ethypharm than you should <\/h2>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
5. How to store Adrenaline Ethypharm<\/h2>\n\n\n\n
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<\/p>\n\n\n\n6. Contents of the packaging and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\nOther sources of information<\/h2>\n\n\n\n
The following information is intended for healthcare professionals only:<\/h2>\n\n\n\n
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<\/p>\n\n\n\nAge<\/strong><\/td> Dose<\/strong><\/td><\/tr> Over 12 years<\/td> 0.5 mg im (0.5 ml 1 mg \/ ml solution for injection )0.3 mg im (0.3 ml 1 mg \/ ml solution for injection ) if the child is small or pre-pubertal<\/td><\/tr> 6-12 years<\/td> 0.3 mg im (0.3 ml 1 mg \/ ml solution for injection )<\/td><\/tr> 6 months – 6 years<\/td> 0.15 mg im (0.15 ml 1 mg \/ ml solution for injection )<\/td><\/tr> For 6 months<\/td> 0.01 mg \/ kg im (0.01 ml \/ kg 1 mg \/ ml solution for injection )<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
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