100 IU \/ ml (International Units \/ ml) solution for injection in cartridge
human insulin<\/p>\n\n\n\n
Actrapid is human insulin with a fast-acting effect.<\/p>\n\n\n\n
Actrapid is used to lower high blood sugar in patients with diabetes mellitus ( diabetes ). Diabetes is a disease in which your body does not produce enough insulin to keep your blood sugar levels under control. Treatment with Actrapid helps prevent complications of your diabetes.<\/p>\n\n\n\n
Actrapid starts lowering your blood sugar about \u00bd hours after you inject it and the effect lasts for about 8 hours. Actrapid is often given in combination with medium- or long-acting insulin preparations.
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If any of these apply to you, do not use Actrapid. Talk to a doctor, pharmacist, or nurse.
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Before you use Actrapid<\/strong><\/p>\n\n\n\n Certain conditions and activities may affect your need for insulin. Consult a doctor:<\/p>\n\n\n\n Skin changes at the injection site<\/strong><\/p>\n\n\n\n To help prevent changes in the adipose tissue under the skin, e.g. skin thickening, skin shrinkage, or lumps under the skin, you should always change the injection site. It may be that insulin et not work as well if you inject in an area with nodules or in a thickened or shriveled area (see “How to use Actrapid”). Contact your doctor if you notice skin changes at the injection site and before changing the injection site if you are currently injecting in an affected area. Your doctor may advise you to check your blood sugar more often and to adjust your insulin dose or the dose of other diabetes medicines.<\/p>\n\n\n\n Tell your doctor, pharmacist, or nurse if you are taking or have recently taken or might take any other medicines.<\/p>\n\n\n\n Some medicines affect your blood sugar level, which may mean that your insulin dose needs to be changed. Below is a list of the most common medicines that may affect your insulin treatment.<\/p>\n\n\n\n Your blood sugar level may drop (hypoglycemia) if you take:<\/p>\n\n\n\n Your blood sugar level may rise (hyperglycemia) if you take:<\/p>\n\n\n\n Octreotide and lanreotide (for the treatment of acromegaly, a rare hormonal disorder with pituitary overproduction of one of the growth hormones usually in middle-aged adults) can either raise or lower your blood sugar level.<\/p>\n\n\n\n Beta-blockers (for the treatment of hypertension ) may weaken or completely eliminate the first warning signs of low blood sugar.<\/p>\n\n\n\n Pioglitazone (tablets for the treatment of type 2 diabetes )<\/p>\n\n\n\n Some patients who have had type 2 diabetes and heart disease for many years or previous strokes developed heart failure during treatment with pioglitazone and insulin. Tell your doctor as soon as possible if you get signs of heart failure such as unexpected shortness of breath, rapid weight gain, or local swelling ( edema ).<\/p>\n\n\n\n If you have taken any of these medicines, talk to your doctor, pharmacist, or nurse.<\/p>\n\n\n\n Talk to your doctor, pharmacist or nurse before using this medicine during pregnancy or breast-feeding.<\/p>\n\n\n\n Ask your doctor if you can drive or use machines:<\/p>\n\n\n\n If your blood sugar is low or high, it can affect your ability to concentrate and react and therefore also your ability to drive or use machines. Remember that you can put yourself and others at risk.<\/p>\n\n\n\n Actrapid contains less than 1 mmol sodium (23 mg) per dose, ie Actrapid is essential ‘sodium-free’.<\/p>\n\n\n\n Dose and when you take your insulin<\/strong> Always use your insulin and make dose adjustments exactly as your doctor advised. If you are not sure, talk to a doctor, pharmacist, or nurse.<\/p>\n\n\n\n Eat a meal or snack that contains carbohydrates within 30 minutes of injection to avoid low blood sugar.<\/p>\n\n\n\n Only change insulin preparations on the advice of a doctor. If your doctor has switched you from one type of insulin or brand to another, your dose may need to be adjusted by your doctor.<\/p>\n\n\n\n Actrapid can be used in children and adolescents<\/p>\n\n\n\n Use for special patient groups<\/strong> If you have impaired kidney or liver function or if you are over 65, you need to check your blood sugar more regularly and discuss changes in your insulin dose with your doctor.<\/p>\n\n\n\n How and where to inject<\/strong> Actrapid is injected under the skin ( subcutaneously ). You should never inject yourself directly into a vein ( intravenously ) or muscle ( intramuscularly ). Actrapid Penfill should only be injected under the skin with a reusable pen. Talk to your doctor if you need to inject your insulin using another method.<\/p>\n\n\n\n At each injection, change the injection site within the same area of \u200b\u200bskin you are using. This may reduce the risk of developing lumps or pits in the skin, see<\/p>\n\n\n\n section 4. The best area to inject one is the front of the waist (abdomen), the buttocks, the front of the thighs, or the upper arms. Insulin works faster if you inject it into your waist. Always check your blood sugar regularly.<\/p>\n\n\n\n How Actrapid is injected<\/strong><\/p>\n\n\n\n If you take too much insulin, your blood sugar may become too low (hypoglycemia). See Summary of Serious and Very Common Side Effects in Section 4.<\/p>\n\n\n\n If you forget to take your insulin, your blood sugar may become too high (hyperglycemia). See Diabetes Disorders in Section 4.<\/p>\n\n\n\n Do not stop insulin treatment without talking to a doctor, who will tell you what needs to be done. It can lead to very high blood sugar (severe hyperglycemia) and ketoacidosis. See Diabetes Disorders in Section 4.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them.<\/p>\n\n\n\n Summary of serious and very common side effect s<\/strong> Low blood sugar ( hypoglycemia )<\/strong> is a very common side effect. It may affect more than 1 in 10 users.<\/p>\n\n\n\n Low blood sugar can occur if you:<\/p>\n\n\n\n Signs of low blood sugar:<\/strong> Cold sweats; cool and pale skin; headache; palpitation; nausea; strong hunger; temporary vision changes; drowsiness; unusual fatigue and weakness; anxiety or trembling; feelings of anxiety; confusion; concentration difficulties.<\/p>\n\n\n\n Very low blood sugar can lead to unconsciousness. If left untreated for a very long time, very low blood sugar can cause brain damage (temporary or permanent) and even death. You can regain consciousness faster if you get an injection of the hormone et glucagon from someone who knows how to use it. If you are given glucagon, you will need glucose or a sugar-containing snack as soon as you regain consciousness. If you do not respond to glucagon therapy, you will need to be treated in a hospital<\/p>\n\n\n\n What to do if you get low blood sugar:<\/strong><\/p>\n\n\n\n Tell them that you have diabetes for people who need to know it, what the consequences can be, and also the risk of becoming unconscious due to low blood sugar. Tell them that if you become unconscious, they should put you on the side and get medical attention immediately. They must not give you anything to eat or drink as there is a risk that you will suffocate.<\/p>\n\n\n\n Severe allergic reactions to Actrapid or to any of the other ingredients (so-called systemic allergic reaction ) are very rare<\/strong> but can be life-threatening. It may affect less than 1 in 10,000 users. Contact a doctor immediately:<\/p>\n\n\n\n If you experience any of these, seek medical attention immediately. Skin changes at the injection site:<\/strong> If you inject insulin at the same site, the adipose tissue may either shrink (lipoatrophy) or thicken (lipohypertrophy) (may affect up to 1 in 100 people). Nodules under the skin can also be caused by the accumulation of a protein called amyloid ( cutaneous amyloidosis. How often this occurs is not known). It may be that insulin et not work as well if you inject in an area with nodules or in a thickened or shriveled area. Change the injection site for each injection to prevent these skin changes. List of adverse reactions are<\/strong> Uncommon side effects are<\/strong><\/p>\n\n\n\n May affect less than 1 in 100 users. Signs of allergy:<\/strong> Local allergic reactions (pain, redness, hives, inflammation, bruising, swelling, and itching ) may occur at the injection site. These symptoms usually go away after taking your insulin for a few weeks. If they do not disappear or spread throughout the body, talk to a doctor immediately. See also Severe allergic reactions above. Vision problems:<\/strong> At the beginning of insulin treatment, visual disturbances may occur, but these are usually temporary. Swollen joints:<\/strong> When you start taking insulin, your body may bind water, causing you to swell around the ankles and other joints. This usually goes away soon, otherwise, you should talk to a doctor.<\/p>\n\n\n\n Painful neuropathy <\/strong>(pain due to nerve damage): If your blood sugar level improves very quickly, you may get nerve-related pain. This is called acute painful neuropathy and is usually transient.<\/p>\n\n\n\n Very rare side effect s<\/strong><\/p>\n\n\n\n May affect less than 1 in 10,000 users. Diabetic retinopathy<\/strong> (an eye disease associated with diabetes and can lead to loss of vision): If you have diabetic retinopathy, it can worsen if your blood sugar levels improve very quickly. Ask your doctor about this. Problems with diabetes<\/strong> High blood sugar (hyperglycemia<\/strong><\/p>\n\n\n\n High blood sugar can occur if you:<\/p>\n\n\n\n High blood sugar warning signs:<\/strong><\/p>\n\n\n\n The warning signals appear gradually. They manifest as: increased urine output; thirst; loss of appetite; feeling sick (nausea or vomiting); drowsiness or fatigue; redness; dry skin; dry mouth and a breath that smells of fruit (acetone). What should I do if I get high blood sugar:<\/strong><\/p>\n\n\n\nWarnings and cautions<\/h2>\n\n\n\n
Other medicines and Actrapid<\/h2>\n\n\n\n
Actrapid and alcohol<\/h2>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Actrapid contains sodium<\/h2>\n\n\n\n
3. How to use Actrapid<\/h2>\n\n\n\n
<\/p>\n\n\n\nUse for children and adolescents<\/h2>\n\n\n\n
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<\/p>\n\n\n\nIf you take more insulin than you should<\/h2>\n\n\n\n
If you forget to take your insulin<\/h2>\n\n\n\n
If you stop taking your insulin<\/h2>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
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