{"id":4684,"date":"2020-11-28T10:19:10","date_gmt":"2020-11-28T10:19:10","guid":{"rendered":"https:\/\/zeepedia.com\/?p=4684"},"modified":"2022-11-23T19:05:42","modified_gmt":"2022-11-23T19:05:42","slug":"acnatac","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/acnatac\/","title":{"rendered":"Acnatac &#8211; Clindamycin And Tretinoin Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p><strong>Acnatac 10 mg\/g + 0.25 mg\/g\u00a0gel Clindamycin and Tretinoin<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Acnatac Is And Acnatac How To Use<\/h2>\n\n\n\n<p>Acnatac gel contains the active substances clindamycin and tretinoin.<\/p>\n\n\n\n<p>Clindamycin is an&nbsp;antibiotic.&nbsp;It reduces bacterial growth in&nbsp;acne&nbsp;and&nbsp;inflammation caused by these bacteria.<\/p>\n\n\n\n<p>Tretinoin normalizes the growth of superficial skin cells and causes normal rejection of the cells that clog the hair follicle in areas with&nbsp;acne.&nbsp;It prevents the buildup of sebum and the development of early forms of&nbsp;acne&nbsp;(blackheads).<\/p>\n\n\n\n<p>These active substances are more effective when combined than when used separately.<\/p>\n\n\n\n<p>Acnatac gel is used on the skin to treat\u00a0<a href=\"https:\/\/zeepedia.com\/diseases\/acne\/\">acne<\/a>\u00a0in patients 12 years of age and older.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/amzn.to\/3XFlYKX\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/zeepedia.com\/wp-content\/uploads\/2022\/11\/acnatac.jpg\" alt=\"acnatac gel\" class=\"wp-image-35335\" width=\"505\" height=\"256\" srcset=\"https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/11\/acnatac.jpg 621w, https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/11\/acnatac-300x152.jpg 300w\" sizes=\"auto, (max-width: 505px) 100vw, 505px\" \/><\/a><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before You Use Acnatac<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Use Acnatac:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are pregnant<\/li><li>If you are planning to become pregnant<\/li><li>If you are allergic to clindamycin, tretinoin, or any of the other ingredients of this medicine (listed in section 6).<\/li><li>If you are allergic to lincomycin.<\/li><li>If you have a&nbsp;chronic&nbsp;inflammatory&nbsp;bowel disease (eg&nbsp;Crohn&#8217;s disease&nbsp;or&nbsp;ulcerative colitis).<\/li><li>If you have previously had&nbsp;colitis&nbsp;in connection with antibiotic treatment which is characterized by prolonged, severe diarrhea or stomach cramps.<\/li><li>If you or a family member have ever had skin <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/getting-a-cancer-message\/\">cancer<\/a>.<\/li><li>If you suffer from&nbsp;acute&nbsp;eczema&nbsp;characterized by inflamed, red, dry, and scaly skin.<\/li><li>If you suffer from&nbsp;rosacea, a skin disease that affects the face and is characterized by&nbsp;redness, pimples, and skin peeling.<\/li><li>If you suffer from other acute inflammatory skin conditions (eg hair follicle inflammation), especially around the mouth (perioral&nbsp;dermatitis&nbsp;).<\/li><li>If you suffer from certain special forms of&nbsp;acne vulgaris&nbsp;that are characterized by blisters and deep, nodulocystic&nbsp;acne&nbsp;(acne conglobata and acne fulminans).<\/li><\/ul>\n\n\n\n<p>Do not use this medicine without consulting your doctor, if any of the above apply to you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Avoid getting the medicine in the mouth, eyes, mucous membranes, and on the skin that is damaged or has&nbsp;eczema.&nbsp;Be careful when applying&nbsp;gel&nbsp;to sensitive skin areas.&nbsp;If you accidentally get&nbsp;the gel&nbsp;in your eyes, rinse with plenty of lukewarm water.<\/li><li>If you are a woman of&nbsp;childbearing potential, do not use <em>Acnatac gel<\/em> unless you are taking contraceptives at the same time (see also section \u201cPregnancy, breast-feeding and fertility\u201d).<\/li><li>If you get long-term or severe diarrhea or stomach cramps, stop using the medicine and talk to your doctor immediately.<\/li><li>If you have&nbsp;atopic eczema&nbsp;(&nbsp;chronic, itchy&nbsp;inflammation&nbsp;of the skin), talk to your doctor before using this medicine.<\/li><li>Exposure to the sun or artificial light (such as sunlight) should be avoided.&nbsp;This is because the drug can make your skin more susceptible to sun damage and other adverse effects of the sun.&nbsp;An effective sunscreen with a sun protection factor (SPF) of at least 30 and protective clothing (such as a sun hat) should always be used when you are outdoors.&nbsp;<br>If your facial skin still burns, stop using the medicine until the skin has healed.<\/li><li>Talk to your doctor if you get acute&nbsp;dermatitis when using this medicine.<\/li><li>Acnatac should not be applied concomitantly with other preparations used on the skin.&nbsp;This also applies to cosmetics (see also the section \u201cOther medicines and Acnatac\u201d).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Acnatac<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;This also applies to over-the-counter medicines and herbal medicines.&nbsp;The reason is that Acnatac may affect the effectiveness of other medicines.&nbsp;Other medicines may also affect the way Acnatac works<\/p>\n\n\n\n<p>If you have used any skin preparation that contains sulfur, salicylic acid, benzoyl peroxide, resorcinol, or other chemical abrasives, then you must wait until the effect of these has subsided before you start using Acnatac.&nbsp;Your doctor may tell you when you can start treatment with Acnatac.<\/p>\n\n\n\n<p>Do not use medicinal soap\/cleanser or scrubbing solutions with a strong dehydrating effect during ongoing treatment with Acnatac.&nbsp;You should be careful when using the following which may have a dehydrating effect;&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Soaps with abrasives<\/li><li>Soaps<\/li><li>Cosmetics<\/li><li>Products with a high concentration of alcohol<\/li><li>Skin tightening agents<\/li><li>Spices<\/li><li>Lime<\/li><\/ul>\n\n\n\n<p>Talk to your doctor before using this medicine with other medicines that contain:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Erythromycin<\/li><li>Metronidazole<\/li><li>Aminoglycoside&nbsp;is<\/li><li>Other&nbsp;antibiotics<\/li><li>Corticosteroid&nbsp;is<\/li><li>Neuromuscular blocking drugs e.g.&nbsp;muscle relaxants used in anesthesia.<\/li><\/ul>\n\n\n\n<p>Warfarin&nbsp;or similar blood thinners.&nbsp;You may have an easier time getting a hemorrhage.&nbsp;Your doctor may need to take regular blood tests to check how well your blood is coagulating.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding, And Fertility<\/h2>\n\n\n\n<p>DO NOT use Acnatac if you are pregnant or planning to become pregnant.&nbsp;Your doctor can give you more information.<\/p>\n\n\n\n<p>You should not use this medicine if you are breastfeeding.&nbsp;It is not known if Acnatac passes into breast milk and harms the baby.<\/p>\n\n\n\n<p>If you are a woman of&nbsp;childbearing potential, you should use contraception while you are being treated with this medicine and for another month after stopping treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>Acnatac is unlikely to have any effect on the ability to drive or use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Acnatac Contains Methyl Parahydroxybenzoate, Propyl Parahydroxybenzoate, And Butylhydroxytoluene<\/h2>\n\n\n\n<p>Methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216) may cause an&nbsp;allergic reaction&nbsp;(possibly delayed).<\/p>\n\n\n\n<p>Butylhydroxytoluene (E321) may cause local skin reactions (eg <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/contact-dermatitis\/\">contact dermatitis<\/a>) or be irritating to eyes and mucous membranes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Use Acnatac<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>The recommended&nbsp;dose&nbsp;is:<\/strong><\/p>\n\n\n\n<p>An amount of Acnatac as large as a pea should be applied once a day at bedtime.<br><\/p>\n\n\n\n<p><strong>Method of administration<\/strong><\/p>\n\n\n\n<p>Wash your face gently with mild soap and warm water and wipe your face dry with a towel.&nbsp;Press a lot of&nbsp;gel, as big as a pea, on your fingertip.&nbsp;Gently&nbsp;dab&nbsp;one&nbsp;gel&nbsp;on your forehead, chin, nose, and both cheeks, and then gently smear it all over your face.<\/p>\n\n\n\n<p>Do not use more medicines than your doctor advised.&nbsp;Also, do not treat more often than your doctor has instructed you to.&nbsp;Too much&nbsp;gel&nbsp;can irritate the skin and does not give a faster or better result.<\/p>\n\n\n\n<p><strong>Treatment time<\/strong><\/p>\n\n\n\n<p>To get the best results with Acnatac, it is necessary to use it properly and not stop using it as soon as your&nbsp;acne&nbsp;starts to get better.&nbsp;It can usually take several weeks for the optimal effect to be achieved.&nbsp;In some cases, it can take up to 12 weeks.&nbsp;Contact your doctor if the symptoms persist for more than 12 weeks, as it may be necessary for your doctor to re-evaluate your treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Use More Acnatac Than You Should<\/h2>\n\n\n\n<p>You will not get a faster or better result if you use more Acnatac than recommended.&nbsp;If you use too much,&nbsp;redness, scaling or discomfort may occur.&nbsp;If this happens, wash your face gently with mild soap and lukewarm water.&nbsp;Discontinue use of the drug until all these symptoms have disappeared.<\/p>\n\n\n\n<p>Overdose can also result in<em> acnatac gel side effects<\/em>&nbsp;on your stomach and intestines;&nbsp;such as <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Stomach <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a><\/li><li>Nausea<\/li><li>Vomiting<\/li><li>Diarrhea&nbsp;<\/li><\/ul>\n\n\n\n<p>If this happens, stop using the medicine and contact your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Use Acnatac<\/h2>\n\n\n\n<p>If you forget to use Acnatac at bedtime, skip the next&nbsp;dose&nbsp;at the usual time.&nbsp;You should not double the&nbsp;dose&nbsp;to compensate for the&nbsp;missed dose.<\/p>\n\n\n\n<p>If you have any further questions about the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Acnatac Side Effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Acne, dry skin, skin redness, increased sebum production, photosensitivity reaction,&nbsp;itching, rash, scaly rash, sunburn.<\/li><li>The reaction at the application site such as <ul><li>Burning sensation<\/li><li>Inflamed skin<\/li><li>Dryness<\/li><li>Reddening of the skin<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><em>Rare Acnatac gel side effects<\/em> <em>(may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hypersensitivity<\/li><li>Hypothyroidism symptoms such as <ul><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/fatigue-syndrome\/\">Fatigue<\/a><\/li><li>Weakness<\/li><li>Weight gain<\/li><li>Dry hair<\/li><li>Coarse pale skin<\/li><li>Hair loss<\/li><li>Increased sensitivity to <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">cold<\/a><\/li><\/ul><\/li><li>Headache<\/li><li>Eye irritation<\/li><li>Gastroenteritis&nbsp;(&nbsp;inflammation&nbsp;of any part of the gastrointestinal tract)<\/li><li>Nausea<\/li><li>Inflamed skin,&nbsp;herpes&nbsp;simplex (cold sores), spotty rash (small, flat red spots), bleeding in the skin, burning sensation in the skin, pigment loss in the skin, and skin irritation.<\/li><li>The reaction at the application site such as <ul><li>Irritation<\/li><li>Swelling<\/li><li>Superficial skin damage<\/li><li>Discoloration<\/li><li>Itching<\/li><li>Flaking<\/li><\/ul><\/li><li>Feeling of heat, pain.<\/li><\/ul>\n\n\n\n<p><em>Reporting of <\/em>Acnatac gel side effects<\/p>\n\n\n\n<p>If you get any side effects, talk to your doctor, pharmacist, or nurse.&nbsp;This includes any possible side effects not listed in this leaflet.&nbsp;You can also report side effects directly to the Medical Products Agency,&nbsp;www.lakemedelsverket.se.&nbsp;By reporting side effects, you can help increase drug safety information.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Acnatac<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not store above 25 \u00b0 C.&nbsp;Do not freeze.<\/li><li>Close the tube tightly.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton and tube after &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Shelf life after first opening: 3 months<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are clindamycin and tretinoin.&nbsp;1 g of&nbsp;gel&nbsp;contains 10 mg (1%) of clindamycin (as clindamycin phosphate) and 0.25 mg (0.025%) of tretinoin.<br><\/li><li>The other ingredients are  <ul><li>Purified water<\/li><li>Glycerol<\/li><li>Carbomer<\/li><li>Methyl parahydroxybenzoate (E218)<\/li><li>Polysorbate 80<\/li><li>Disodium edetate<\/li><li>Anhydrous citric acid<\/li><li>Propyl parahydroxybenzoate (E216)<\/li><li>Butylhydroxytoluene (E321)<\/li><li>Trometamol<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>This medicine is a clear, yellow&nbsp;gel.<\/li><li>Medicines are available in aluminum tubes containing 30 g of&nbsp;gel&nbsp;and 60 g of&nbsp;gel, respectively.<\/li><li>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Meda AB<\/p>\n\n\n\n<p>Box 906<\/p>\n\n\n\n<p>SE-170 09 Solna<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Meda Pharma GmbH &amp; Co.&nbsp;KG<\/p>\n\n\n\n<p>Benzstrasse 1<\/p>\n\n\n\n<p>61352 Bad Homburg<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>Madaus GmbH<\/p>\n\n\n\n<p>L\u00fctticher Stra\u00dfe 5<\/p>\n\n\n\n<p>53842 Troisdorf<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<p>Cyprus, Greece: Acnatac, 10 mg \/ g + 0.25 mg \/ g \u03b3\u03b5\u03bb\u03b7<\/p>\n\n\n\n<p>Hungary: Annex<\/p>\n\n\n\n<p>Bulgaria, Denmark, Finland, Iceland, Italy, Poland, Portugal, Romania, Slovakia, Sweden, Czech Republic, Germany, Austria: Acnatac<\/p>\n\n\n\n<p>Ireland, Malta, UK: Treclin<\/p>\n\n\n\n<p>Estonia, Latvia, Lithuania, Netherlands, Spain: Treclinac<\/p>\n\n\n\n<p>Belgium, Luxembourg: Treclinax<\/p>\n\n\n\n<p>Norway, Slovenia: Zalna<\/p>\n\n\n\n<p>France: Zane<\/p>\n","protected":false},"excerpt":{"rendered":"<p>ACNATAC has the active elements clindamycin and tretinoin. It is used on the skin to delight acne in patients 12 years and older.<\/p>\n","protected":false},"author":2,"featured_media":35335,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"yes","footnotes":""},"categories":[2201,2200],"tags":[11825,11828,11829,11823,11819,11822,11830,11824,11827,11821,11826,11820],"class_list":["post-4684","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-a","category-medicines","tag-acnatac","tag-acnatac-gel","tag-benefits-of-acnatac","tag-benefits-of-clindamycin-and-tretinoin","tag-clindamycin-and-tretinoin","tag-clindamycin-and-tretinoin-gel","tag-side-effects-of-acnatac","tag-side-effects-of-clindamycin-and-tretinoin","tag-what-acnatac-is-used-for","tag-what-clindamycin-and-tretinoin-is-used-for","tag-what-is-acnatac","tag-what-is-clindamycin-and-tretinoin"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4684","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=4684"}],"version-history":[{"count":41,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4684\/revisions"}],"predecessor-version":[{"id":35336,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4684\/revisions\/35336"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media\/35335"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=4684"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=4684"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=4684"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}