{"id":4605,"date":"2020-11-26T11:43:33","date_gmt":"2020-11-26T11:43:33","guid":{"rendered":"https:\/\/zeepedia.com\/?p=4605"},"modified":"2021-08-25T06:51:52","modified_gmt":"2021-08-25T06:51:52","slug":"acetylsalicylic-acid-caffeine-apofri","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/acetylsalicylic-acid-caffeine-apofri\/","title":{"rendered":"Acetylsalicylic acid \/ Caffeine Apofri – Caffeine uses, dose and side effects"},"content":{"rendered":"\n

500 mg \/ 50 mg effervescent tablet is
acetylsalicylic acid<\/a> \/ caffeine<\/a><\/p>\n\n\n\n

What Acetylsalicylic Acid \/ Caffeine Apofri is and what it is used for<\/h2>\n\n\n\n

Acetylsalicylic acid \/ Caffeine Apofri contains two active substances, acetylsalicylic acid, and caffeine. Acetylsalicylic acid \/ Caffeine Apofri has analgesic, anti-inflammatory, and antipyretic properties. Acetylsalicylic acid relieves pain by counteracting the formation of special substances, prostaglandins. The antipyretic effect is due to the fact that acetylsalicylic acid increases the body’s heat release. Caffeine enhances the analgesic effect of acetylsalicylic acid. Caffeine also has an analgesic effect through its astringent effect on dilated blood vessels in the brain e.g. in migraine. Caffeine also has an invigorating effect.<\/p>\n\n\n\n

You must talk to a doctor if you do not feel better or if you feel worse after 3 days with fever and migraine and within 5 days with pain.<\/p>\n\n\n\n

This medicine is used for temporary mild to moderate pain conditions, e.g. headaches, including migraine headaches, toothaches, muscle, and joint pain, menstrual cramps, and fever in colds.<\/p>\n\n\n\n

Acetylsalicylic acid and caffeine contained in Acetylsalicylic acid \/ Caffeine Apofri may also be approved for the treatment of other conditions not mentioned in this product information. Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n

What you need to know before you use Acetylsalicylic acid \/ Caffeine Apofri<\/h2>\n\n\n\n

Do not use Acetylsalicylic acid \/ Caffeine Apofri<\/h2>\n\n\n\n

– if you are allergic to acetylsalicylic acid, caffeine, or any of the other ingredients of this medicine (listed in section 6).<\/p>\n\n\n\n

– if you have had a hypersensitivity reaction such as asthma, difficulty breathing, hay fever, or hives when taking acetylsalicylic acid or certain other medicines for pain and inflammation within the group NSAIDs (non-steroidal anti-inflammatory drugs)<\/p>\n\n\n\n

– if you are bleeding<\/p>\n\n\n\n

– if you have reduced platelet count ( thrombocytopenia )<\/p>\n\n\n\n

– if you have stomach ulcers<\/p>\n\n\n\n

– if you have severe kidney disease or cirrhosis of the liver ( liver cirrhosis )<\/p>\n\n\n\n

– if you have severe heart failure<\/p>\n\n\n\n

– during the last three months of pregnancy (see “Pregnancy and breast-feeding”)<\/p>\n\n\n\n

Warnings and cautions<\/h2>\n\n\n\n

Talk to your doctor before using Acetylsalicylic acid \/ Caffeine Apofri<\/strong> :<\/p>\n\n\n\n

– if you know you are allergic (hypersensitive) to acetylsalicylic acid, ibuprofen, or any other anti-inflammatory drug.<\/p>\n\n\n\n

– if you are taking medicines that thin the blood to prevent blood clots ( anticoagulants )<\/p>\n\n\n\n

– if you are taking diuretics<\/p>\n\n\n\n

– if you have mild to moderate heart failure<\/p>\n\n\n\n

– if you have mild to the moderate liver or kidney function<\/p>\n\n\n\n

– if you have high blood pressure<\/p>\n\n\n\n

– if you have asthma<\/p>\n\n\n\n

– if you have had stomach ulcers<\/p>\n\n\n\n

Children and young people<\/h2>\n\n\n\n

Acetylsalicylic acid \/ Caffeine Apofri should not be given to children under 14 years of age.<\/p>\n\n\n\n

Medicines containing acetylsalicylic acid should not be given to people under 18 years of age without a fever without consulting a doctor due to the risk of developing Reye’s syndrome, a rare but serious medical condition.<\/p>\n\n\n\n

Other medicines and Acetylsalicylic acid \/ Caffeine Apofri<\/h2>\n\n\n\n

Acetylsalicylic acid \/ Caffeine Apofri can affect or be affected by:<\/p>\n\n\n\n

\u2022 Anticoagulants (medicines for blood clots)<\/p>\n\n\n\n

\u2022 Corticosteroids (medicines for inflammation such as cortisone or prednisolone ) and other NSAIDs (medicines for pain and inflammation such as ibuprofen )<\/p>\n\n\n\n

\u2022 Metamizole (for pain and fever)<\/p>\n\n\n\n

\u2022 Digoxin (medicine for arrhythmias in the heart)<\/p>\n\n\n\n

Ciclosporin and tacrolimus (against the rejection of transplanted organs)<\/p>\n\n\n\n

\u2022 Methotrexate (for cancer and rheumatism)<\/p>\n\n\n\n

\u2022 Valproic acid (for epilepsy )<\/p>\n\n\n\n

\u2022 Nicotinic acid (for high blood fats)<\/p>\n\n\n\n

\u2022 Diuretics and medicines for high blood pressure<\/p>\n\n\n\n

\u2022 Probenecid (for gout )<\/p>\n\n\n\n

\u2022 Adenosine (for arrhythmias in the heart)<\/p>\n\n\n\n

\u2022 Clozapine (for schizophrenia)<\/p>\n\n\n\n

\u2022 Lithium (for manic depressive illness)<\/p>\n\n\n\n

\u2022 Sulphonylureas (medicines for type II diabetes )<\/p>\n\n\n\n

\u2022 Ciprofloxacin, Norfloxacin ( antibiotics for infections )<\/p>\n\n\n\n

\u2022 Phenylpropanolamine (anti-allergy medicine )<\/p>\n\n\n\n

\u2022 Fluvoxamine (antidepressant)<\/p>\n\n\n\n

\u2022 Phenytoin and carbamazepine (medicines used to treat epilepsy ).
<\/p>\n\n\n\n

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Higher doses than those recommended can lead to serious risks. Do not use different types of painkillers at the same time without a doctor’s prescription.<\/p>\n\n\n\n

Acetylsalicylic acid \/ Caffeine Apofri with food, drink, and alcohol<\/h2>\n\n\n\n

Acetylsalicylic acid \/ Caffeine Apofri in combination with alcohol may increase the risk of stomach ulcers.<\/p>\n\n\n\n

Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n

Acetylsalicylic acid \/ Caffeine Apofri, like many anti-inflammatory drugs (so-called NSAIDs ), can make it difficult to conceive and is therefore not recommended for women trying to conceive. The effect is temporary, ie ceases when you stop using these types of drugs.<\/p>\n\n\n\n

Pregnant women should not use Acetylsalicylic acid \/ Caffeine Apofri during the last three months of pregnancy. Intake of Acetylsalicylic Acid \/ Caffeine Apofri should be avoided by women who are planning to become pregnant or are pregnant. Treatment during any part of the pregnancy should be done only after a doctor’s prescription .<\/p>\n\n\n\n

Acetylsalicylic acid \/ Caffeine Apofri passes into breast milk but is unlikely to affect the breast-feeding baby. However, consult a physician if more than temporary use of Acetylsalicylic acid \/ Caffeine Apofri during breast-feeding.<\/p>\n\n\n\n

Driving and using machines<\/h2>\n\n\n\n

Acetylsalicylic acid \/ Caffeine Apofri may impair the ability of some people to react, for example, due to side effects such as dizziness and fatigue. This should be borne in mind at times when sharper attention is required, for example when driving a car.<\/p>\n\n\n\n

You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n

Acetylsalicylic acid \/ Caffeine Apofri contains sodium<\/h2>\n\n\n\n

This medicine contains 276 mg of sodium (the main ingredient in table salt\/table salt) per effervescent tablet. This corresponds to 14% of the maximum recommended daily intake of sodium for adults. Consult your doctor or pharmacist if you need 2 or more effervescent tablets daily for a long period of time, especially if you have been prescribed a low-salt (sodium-poor) diet.<\/p>\n\n\n\n

How to use Acetylsalicylic acid \/ Caffeine Apofri<\/h2>\n\n\n\n

Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n

Acetylsalicylic acid \/ Caffeine Apofri effervescent tablets are intended for temporary discomfort.<\/p>\n\n\n\n

The recommended<\/em> dose for adults and adolescents over 14 years: 1-2 effervescent tablets 1-3 times a day or according to a doctor’s prescription, a maximum of 6 tablets per day. More than 2 tablets at a time do not provide a better analgesic effect. Contact a doctor if symptoms worsen or do not improve within 3 days for fever and migraine and within 5 days for pain.<\/p>\n\n\n\n

Warning:<\/strong> Do not give to people under 18 years of age with fever without consulting a doctor due to the risk of developing Reye’s syndrome, a rare but serious medical condition.<\/p>\n\n\n\n

Dissolve the effervescent tablets in half a glass of water.<\/p>\n\n\n\n

Because caffeine is invigorating, it may be inappropriate to take this medicine at night.<\/p>\n\n\n\n

Use for children and adolescents<\/h2>\n\n\n\n

Acetylsalicylic acid \/ Caffeine Apofri should not be given to children under 14 years of age.<\/p>\n\n\n\n

Symptoms of overdose can be: headache, dizziness, cramps, vomiting, tinnitus, palpitations ( tachycardia ), abdominal pain, irritation, anxiety, and shortness of breath are examples of symptoms of overdose.<\/p>\n\n\n\n

If you forget to use Acetylsalicylic acid \/ Caffeine Apofri<\/h2>\n\n\n\n

Do not take a double dose to make up for a forgotten tablet.<\/p>\n\n\n\n

If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n

4. Possible side effects<\/h2>\n\n\n\n

Like all medicines, this medicine can cause side effects, although not everybody gets them.<\/p>\n\n\n\n

Common (affects more than 1 user in 100):<\/em><\/p>\n\n\n\n

\u2022 stomach upset, such as acid reflux, heartburn, and nausea<\/p>\n\n\n\n

\u2022 increased tendency for bleeding<\/p>\n\n\n\n

\u2022 palpitations, tremors, anxiety, insomnia.
<\/p>\n\n\n\n

Uncommon (affects less than 1 user in 100):<\/em><\/p>\n\n\n\n

\u2022 fatigue, sweating, dizziness, and tinnitus<\/p>\n\n\n\n

\u2022 hypersensitivity reactions such as hives, hay fever, or shortness of breath<\/p>\n\n\n\n

\u2022 stomach ulcers and stomach bleeding.<\/p>\n\n\n\n

Rare (affects less than 1 user in 1,000):<\/em><\/p>\n\n\n\n

\u2022 reduction in platelet count ( thrombocytopenia )<\/p>\n\n\n\n

Dissolution of the red blood cells ( hemolysis ) in those who have a hereditary deficiency of the metabolic enzyme glucose -6-phosphate dehydrogenase<\/p>\n\n\n\n

\u2022 severe bleeding in the gastrointestinal tract<\/p>\n\n\n\n

\u2022 severe skin reactions<\/p>\n\n\n\n

\u2022 liver effects<\/p>\n\n\n\n

\u2022 kidney effects.<\/p>\n\n\n\n

Minor blood loss can in some cases lead to anemia.<\/p>\n\n\n\n

Additional side effects are in children and adolescents<\/strong><\/p>\n\n\n\n

Acetylsalicylic acid may increase the risk of Reye’s syndrome in children and adolescents associated with viral diseases, especially chickenpox and influenza. Reye’s syndrome is very rare. The symptoms are signs of brain swelling and liver damage, sometimes with low blood sugar.<\/p>\n\n\n\n

Reporting of side effects<\/em><\/p>\n\n\n\n

If you get any side effects, talk to your doctor, pharmacist, or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly to the Medical Products Agency, www.lakemedelsverket.se. By reporting side effects, you can help increase drug safety information. <\/p>\n\n\n\n

5. How to store Acetylsalicylic acid \/ Caffeine Apofri<\/h2>\n\n\n\n

Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n

Store in the original package. Close the tube tightly. Moisture sensitive.<\/p>\n\n\n\n

Do not use this medicine after the expiry date which is stated on the carton and tube after EXP. date. The expiration date is the last day of the specified month.<\/p>\n\n\n\n

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n

6. Contents of the packaging and other information<\/h2>\n\n\n\n

Content declaration<\/h2>\n\n\n\n

The active substances are acetylsalicylic acid 500 mg, caffeine 50 mg.<\/p>\n\n\n\n

The other ingredients are anhydrous citric acid, povidone, sodium bicarbonate, anhydrous sodium carbonate, simethicone, sodium dihydrogen citrate, sodium citrate, mannitol, and docusate sodium.<\/p>\n\n\n\n

What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n

The effervescent tablets are white, round, flat and 22 mm in diameter.<\/p>\n\n\n\n

The effervescent tablets are available in plastic tubes containing 10 or 25 effervescent tablets.<\/p>\n\n\n\n

Pack sizes:<\/em><\/p>\n\n\n\n

10, 15, 20, and 25 effervescent tablets in plastic tubes.<\/p>\n\n\n\n

10 pcs (1 plastic tube x 10 effervescent tablets ), 15 pcs (1×15), 20 pcs (1×20, 2×10), 25 pcs (1×25), 30 pcs (3×10, 2×15), 40 pcs (4×10, 2×20), 45 pcs ( 3×15), 50 pcs (5×10, 2×25 pcs), 60 pcs (6×10, 4×15, 3×20) in outer carton.<\/p>\n\n\n\n

Not all pack sizes may be marketed.<\/p>\n\n\n\n

Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n

Marketing Authorisation Holder<\/em><\/p>\n\n\n\n

Apofri AB<\/p>\n\n\n\n

Box 120<\/p>\n\n\n\n

182 12 Danderyd<\/p>\n\n\n\n

Tel .: 08-544 960 30
<\/p>\n\n\n\n

Manufacturer<\/em><\/p>\n\n\n\n

RosenPharma as<\/p>\n\n\n\n

no. of descriptive 265<\/p>\n\n\n\n

664 81 Veversk\u00e9 Kn\u00ednice<\/p>\n\n\n\n

Czech Republic<\/p>\n","protected":false},"excerpt":{"rendered":"

Acetylsalicylic acid \/ Caffeine Apofri contains two active substances, acetylsalicylic acid, and caffeine. Acetylsalicylic acid \/ Caffeine Apofri has analgesic, anti-inflammatory, and antipyretic properties. Acetylsalicylic acid relieves pain by counteracting the formation of special substances, prostaglandins. The antipyretic effect is due to the fact that acetylsalicylic acid increases the body’s heat release. Caffeine enhances the analgesic effect of acetylsalicylic acid. Caffeine also has an analgesic effect through its astringent effect on dilated blood vessels in the brain e.g. in migraine. Caffeine also has an invigorating effect.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2201,2200],"tags":[5484,6954,11915,11910,11913,11918,9320,11919,11914,9319,11912,11917,5485,11916,11911],"class_list":["post-4605","post","type-post","status-publish","format-standard","hentry","category-a","category-medicines","tag-acetylsalicylic-acid","tag-acetylsalicylic-acid-tablet","tag-caffeine","tag-caffeine-apofri","tag-caffeine-apofri-tablet","tag-caffeine-tablet","tag-side-effects-of-acetylsalicylic-acid","tag-side-effects-of-caffeine","tag-side-effects-of-caffeine-apofri","tag-what-acetylsalicylic-acid-is-used-for","tag-what-caffeine-apofri-is-used-for","tag-what-caffeine-is-used-for","tag-what-is-acetylsalicylic-acid","tag-what-is-caffeine","tag-what-is-caffeine-apofri"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4605","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=4605"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4605\/revisions"}],"predecessor-version":[{"id":13209,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/4605\/revisions\/13209"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=4605"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=4605"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=4605"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}