100 units\/ml solution for injection in cartridge
Insulin glargine<\/p>\n\n\n\n
ABASAGLAR contains insulin glargine. This is a modified insulin, very similar to human insulin.<\/p>\n\n\n\n
ABASAGLAR is used to treat diabetes mellitus in adults, adolescents and children from 2 years of age.<\/p>\n\n\n\n
Diabetes mellitus is a disease in which the body does not produce enough insulin to control blood sugar levels. Insulin glargine has a long and even blood sugar lowering effect.<\/p>\n\n\n\n
If you are allergic to insulin glargine or any of the other ingredients of this medicine (listed in section 6).<\/p>\n\n\n\n
Talk to a doctor, pharmacist or nurse before using ABASAGLAR.<\/p>\n\n\n\n
Be sure to follow the dosing instructions and instructions for control (of blood and urine), diet and physical activities (physical work and exercise) as discussed with your doctor.
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If your blood sugar is too low ( hypoglycaemia ), follow the instructions for treating hypoglycaemia (see box at the end of the package leaflet).
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Skin changes at the injection site:<\/p>\n\n\n\n
If you inject insulin too often in the same place, the adipose tissue may either shrink (lipoatrophy) or thicken (lipohypertrophy). Nodules under the skin can also be caused by the accumulation of a protein called amyloid ( cutaneous amyloidosis). It may be that insulin et not work as well if you inject in an area with nodules. Change the injection site for each injection to prevent these skin changes.<\/p>\n\n\n\n
Travel<\/em><\/p>\n\n\n\n Consult your doctor before setting out on a journey. You may need to raise questions about:<\/p>\n\n\n\n – availability of your insulin in the country you are visiting,<\/p>\n\n\n\n – availability of insulin, etc.,<\/p>\n\n\n\n – storage of insulin during the journey,<\/p>\n\n\n\n – times for meals and insulin use during the trip,<\/p>\n\n\n\n – possible effects of travel to other time zones,<\/p>\n\n\n\n – any new health risks in the countries you visit,<\/p>\n\n\n\n – what to do in an emergency if you feel unwell or become ill<\/p>\n\n\n\n Diseases and injuries<\/em><\/p>\n\n\n\n In the following situations, the management of your diabetes may require extra care (for example, adjustment of insulin dose, blood and urine tests):<\/p>\n\n\n\n – If you are ill or have a serious accident, your blood sugar may rise ( hyperglycaemia).<\/p>\n\n\n\n – If you do not eat enough, your blood sugar may become too low ( hypoglycaemia ).<\/p>\n\n\n\n In most cases, you will need medical attention. Contact a doctor at an early stage.<\/strong> If you have type 1 diabetes (insulin-dependent diabetes mellitus ), you should not stop taking insulin and you should continue to add enough carbohydrates. Always tell those who see you or treat you that you need insulin.<\/p>\n\n\n\n Insulin treatment can cause the body to make antibodies against insulin (substances that react with insulin ). This will, although very unusual, require a change in your insulin dose.<\/p>\n\n\n\n Some patients with long-term type 2 diabetes mellitus and heart disease or previous stroke, treated with pioglitazone and insulin, developed heart failure. Tell your doctor as soon as possible if you get signs of heart failure such as increased shortness of breath, rapid weight gain or local swelling (oedema).<\/p>\n\n\n\n Insulin confusions<\/em><\/p>\n\n\n\n You must always check the package and insulin label before each injection, to avoid confusing ABASAGLAR with other insulins.<\/p>\n\n\n\n There is no experience with the use of ABASAGLAR in children under 2 years of age.<\/p>\n\n\n\n Some medicines affect the blood sugar level (lowering the blood sugar, raising the blood sugar or both, depending on the circumstances). In all cases, it may be necessary to adjust your insulin dose to avoid your blood sugar level becoming either too low or too high. Keep this in mind when you start or stop taking another medicine.<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Before taking any medicine, consult your doctor if it may affect your blood sugar level and if so, what to do. Drugs that can lower your blood sugar ( hypoglycaemia ) include:<\/em><\/p>\n\n\n\n – all other medicines used to treat diabetes,<\/p>\n\n\n\n – ACE inhibitors (for the treatment of certain heart conditions or high blood pressure),<\/p>\n\n\n\n – disopyramide (for the treatment of certain heart conditions),<\/p>\n\n\n\n – fluoxetine (for treating depression),<\/p>\n\n\n\n – fibrates (used to lower high levels of blood fats),<\/p>\n\n\n\n – MAO inhibitors (for the treatment of depression),<\/p>\n\n\n\n – pentoxifylline, propoxyphene, salicylates (eg acetylsalicylic acid used as painkillers and<\/p>\n\n\n\n antipyretics),<\/p>\n\n\n\n somatostatin analogues (as octreotide, used in the treatment of a less common disease involving the production of too much growth hormone ),<\/p>\n\n\n\n sulfonamide antibiotics.<\/p>\n\n\n\n Drugs that can raise your blood sugar ( hyperglycaemia ) include:<\/em><\/p>\n\n\n\n – corticosteroid s (e.g. corticosteroid used in the treatment of inflammation s),<\/p>\n\n\n\n – danazol (medicines that affect ovulation),<\/p>\n\n\n\n – diazoxide (for the treatment of hypertension ),<\/p>\n\n\n\n – diuretics (for the treatment of high blood pressure or if you have accumulated too much fluid),<\/p>\n\n\n\n – glucagon (a pancreatic hormone used in the treatment of severe hypoglycaemia ),<\/p>\n\n\n\n – isoniazid (for the treatment of tuberculosis ),<\/p>\n\n\n\n – estrogens and progestogens (eg birth control pills used for birth control),<\/p>\n\n\n\n – phenothiazine derivatives (for the treatment of mental illness),<\/p>\n\n\n\n somatropin ( growth hormone ),<\/p>\n\n\n\n – sympathomimetics (eg epinephrine ( adrenaline ) or salbutamol, terbutaline used in the treatment<\/p>\n\n\n\n of asthma ),<\/p>\n\n\n\n – thyroid hormones (for the treatment of thyroid diseases),<\/p>\n\n\n\n – atypical psychotropic drugs (eg clozapine, olanzapine),<\/p>\n\n\n\n – protease inhibitors (for the treatment of HIV ). Blood sugar levels can sometimes increase and sometimes decrease if you use:<\/em><\/p>\n\n\n\n – beta-blockers (for the treatment of hypertension ),<\/p>\n\n\n\n – clonidine (for the treatment of hypertension ),<\/p>\n\n\n\n lithium salts (for the treatment of mental illness). Pentamidine (used to treat certain infections caused by parasites) can cause hypoglycaemia, which can sometimes be followed by hyperglycaemia.<\/p>\n\n\n\n In addition, beta-blockers, as well as other sympatholytic drugs (eg clonidine, guanethidine and reserpine), may cause the first warning signs that make you recognize hypoglycaemia to be weakened or absent.<\/p>\n\n\n\n If you are not sure if you are taking any of these medicines, ask your doctor or pharmacist for advice.<\/p>\n\n\n\n Your blood sugar can either be raised or lowered if you drink alcohol.<\/p>\n\n\n\n Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n Tell your doctor if you intend to become pregnant or if you are already pregnant. The insulin dose may need to be adjusted during pregnancy and after delivery. For the sake of the child, it is especially important that your diabetes is monitored and that hypoglycaemia is prevented.<\/p>\n\n\n\n If you are breast-feeding, your insulin dose and diet may need to be adjusted, consult your doctor.<\/p>\n\n\n\n Your ability to concentrate or react may be impaired if:<\/p>\n\n\n\n – you get hypoglycaemia (low blood sugar levels),<\/p>\n\n\n\n – you get hyperglycaemia (elevated blood sugar levels),<\/p>\n\n\n\n – you have vision problems.<\/p>\n\n\n\n Think of the risk of this in all situations where you can expose yourself and others to danger (eg when driving or using machines). Contact your doctor for advice on driving if:<\/p>\n\n\n\n – you often have episodes of hypoglycaemia,<\/p>\n\n\n\n – if the first warning signs that make you recognize hypoglycaemia are weakened or absent.<\/p>\n\n\n\n This medicine contains less than 1 mmol sodium (23 mg) per dose, ie essentially ‘sodium-free’.<\/p>\n\n\n\n Always use this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure.
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Other medicines and ABASAGLAR<\/h2>\n\n\n\n
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<\/p>\n\n\n\nABASAGLAR with alcohol<\/h2>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
ABASAGLAR contains sodium<\/h2>\n\n\n\n
3. How to use ABASAGLAR<\/h2>\n\n\n\n
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