{"id":38854,"date":"2022-12-07T09:00:18","date_gmt":"2022-12-07T09:00:18","guid":{"rendered":"https:\/\/zeepedia.com\/?p=38854"},"modified":"2022-12-09T10:12:01","modified_gmt":"2022-12-09T10:12:01","slug":"zyprexa","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/zyprexa\/","title":{"rendered":"ZYPREXA &#8211; Olanzapine uses, dose and side effects"},"content":{"rendered":"\n<p>2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg, and 20 mg\u00a0coated\u00a0tablets (Olanzapine)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">WHAT ZYPREXA IS AND WHAT IT IS USED FOR?<\/h2>\n\n\n\n<p>ZYPREXA contains the active substance olanzapine.&nbsp;ZYPREXA belongs to the drug&nbsp;group neuroleptics&nbsp;and is used to treat the following conditions:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Schizophrenia, is a disease with symptoms such as hearing, seeing, or sensing something that is not there, delusions, unusual suspiciousness, and withdrawal.\u00a0People with these conditions may also feel depressed, anxious, or tense.<\/li><li>Moderate to severe manic episodes, a condition with symptoms such as excitement and\u00a0euphoria.<\/li><\/ul>\n\n\n\n<p>ZYPREXA prevents the recurrence of these symptoms in patients with bipolar disorder who have responded to olanzapine treatment in the manic phase.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">WHAT YOU NEED TO KNOW BEFORE YOU TAKE ZYPREXA<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take ZYPREXA<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (hypersensitive) to olanzapine or any of the other ingredients of this medicine (listed in section 6).\u00a0An\u00a0allergic reaction\u00a0can manifest itself as a skin rash,\u00a0itching, swollen face, swollen lips, or difficulty breathing.\u00a0If this should occur, contact your doctor.<\/li><li>if you have previously had eye problems such as certain types of\u00a0glaucoma\u00a0(increased pressure in the eye).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking ZYPREXA.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The use of ZYPREXA in elderly patients with dementia is not recommended as it may cause serious\u00a0side effects.<\/li><li>Medicines of this type can cause abnormal movements of the face or tongue.\u00a0Contact your doctor if this occurs.<\/li><li>This type of drug can also cause a combination of fever, shortness of breath, sweating, muscle stiffness, and drowsiness.\u00a0These\u00a0side effects\u00a0occur extremely rarely, but if they occur, contact your doctor immediately.<\/li><li>Weight gain has occurred in patients taking ZYPREXA.\u00a0You and your doctor should check your weight regularly.\u00a0Consider referral to a dietitian or help with a diet list if necessary.<\/li><li>High blood sugar and high blood fat levels (\u00a0triglycerides\u00a0and\u00a0cholesterol\u00a0) have occurred in patients taking ZYPREXA.\u00a0Your doctor should do blood tests for blood sugar and fat levels before you start taking ZYPREXA and then at regular intervals during treatment.<\/li><li>Tell your doctor if you or someone in your family has a history of blood clots, as medicines like these have been associated with blood clots.<\/li><\/ul>\n\n\n\n<p>You must tell your doctor if you suffer from any of the following diseases:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>stroke&nbsp;or mild form of&nbsp;stroke&nbsp;(temporary symptoms of&nbsp;stroke&nbsp;)<\/li><li>Parkinson&#8217;s disease<\/li><li>prostate problems<\/li><li>irritable bowel (paralytic&nbsp;ileus&nbsp;)<\/li><li>liver or kidney disease<\/li><li>blood disease<\/li><li>heart disease<\/li><li>diabetes<\/li><li>convulsions<\/li><li>if you know you may have a salt deficiency as a result of prolonged severe diarrhea and vomiting or use&nbsp;diuretics&nbsp;(&nbsp;diuretics&nbsp;)<\/li><\/ul>\n\n\n\n<p>For demented patients, the doctor must be informed if the patient has had a\u00a0stroke\u00a0or a milder form of\u00a0stroke.<\/p>\n\n\n\n<p>If you are over 65, your&nbsp;blood pressure&nbsp;should be checked regularly by your doctor.<\/p>\n\n\n\n<p><strong>Children and young people<\/strong><\/p>\n\n\n\n<p>ZYPREXA is not intended for patients under 18 years of age.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and ZYPREXA<\/h2>\n\n\n\n<p>Only take other medicines during ZYPREXA treatment if your doctor advises you to do so.\u00a0Together with the following medicines, drowsiness can occur anti-depressants and anti-anxiety drugs, and sleeping aids (sedatives).<\/p>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>You must tell your doctor if you are taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>drugs against Parkinson&#8217;s disease<\/li><li>carbamazepine (for\u00a0epilepsy\u00a0and mood stabilizer), fluvoxamine (for depression), or\u00a0ciprofloxacin\u00a0(\u00a0antibiotic\u00a0) \u2013 it may be necessary to adjust your ZYPREXA\u00a0dose.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">ZYPREXA with alcohol<\/h2>\n\n\n\n<p>Do not drink alcohol during treatment with ZYPREXA, as it, together with alcohol, can cause drowsiness.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.\u00a0You should not take this medicine if you are breastfeeding, as small amounts of ZYPREXA may pass into breast milk.<\/p>\n\n\n\n<p>In newborn babies whose mothers have taken ZYPREXA during the last trimester (the last three months of pregnancy), the following symptoms may occur: tremors, stiff and\/or weak muscles, sleepiness, agitation, breathing problems, and difficulty eating.\u00a0You may need to contact your doctor if your child develops any of these symptoms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>There is a risk that you may feel drowsy while using ZYPREXA.&nbsp;If this happens, do not drive or work with tools or machines and consult your doctor about this.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">ZYPREXA contains lactose<\/h2>\n\n\n\n<p>If you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">HOW TO TAKE ZYPREXA<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The dose&nbsp;and duration of treatment are determined by your doctor.&nbsp;Dose&nbsp;one of ZYPREXA is 5-20 mg per day.&nbsp;Contact your doctor if symptoms return but do not stop taking the medicine unless your doctor tells you to.<\/p>\n\n\n\n<p>It would help if you took ZYPREXA once a day.\u00a0Try to take ZYPREXA at \u200b\u200bthe same time each day either with a meal or between meals.\u00a0The tablets should be taken by mouth and swallowed whole with water.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much ZYPREXA<\/h2>\n\n\n\n<p>Patients who have taken too much ZYPREXA have experienced the following symptoms: fast heart rate, agitation\/aggressiveness, difficulty speaking, involuntary movements (especially of the face or tongue), and loss of consciousness.\u00a0Other symptoms may be\u00a0acute\u00a0confusion, convulsions (\u00a0epilepsy\u00a0),\u00a0coma, a combination of fever, shortness of breath, sweating, muscle stiffness, drowsiness or sleepiness, slow breathing, difficulty breathing, high or low\u00a0blood pressure, and abnormal heart rhythm.<\/p>\n\n\n\n<p>Contact your doctor or hospital immediately if you experience any of the listed symptoms.&nbsp;Take the remaining tablets with you.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take ZYPREXA<\/h2>\n\n\n\n<p>Take your tablets as soon as you remember.&nbsp;Do not take two&nbsp;doses&nbsp;on the same day.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using ZYPREXA<\/h2>\n\n\n\n<p>It is important that you follow your doctor&#8217;s instructions and not stop taking the medicine because you feel better.<\/p>\n\n\n\n<p>If you suddenly stop taking ZYPREXA, you may experience symptoms such as sweating, difficulty sleeping, tremors, anxiety, nausea, and vomiting.\u00a0Your doctor may advise you to reduce the\u00a0dose\u00a0gradually before stopping treatment.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">POSSIBLE SIDE EFFECTS<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Contact your doctor immediately if you get:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>involuntary movement disorders (a common side effect that may affect up to 1 in 10 users) especially in the face or tongue<\/li><li>blood clots in the veins (an uncommon\u00a0side effect\u00a0that may affect up to 1 in 100 people) especially in the legs (symptoms are swelling, pain, and\u00a0redness\u00a0of the legs).\u00a0The blood clots can be transported to the lungs and cause chest pain and difficulty breathing.\u00a0If you experience any of these symptoms, seek medical attention immediately.<\/li><li>a combination of fever, faster breathing, sweating, muscle stiffness, and drowsiness or sleepiness (the frequency of this\u00a0side effect\u00a0cannot be estimated from the available data).<\/li><\/ul>\n\n\n\n<p>Very common\u00a0side effects\u00a0(which may affect more than 1 in 10 users) include weight gain;\u00a0sleepiness and increased levels of\u00a0prolactin\u00a0in the blood.\u00a0At the beginning of treatment, some people may feel dizzy or faint (with a slow heart rate), especially when getting up from a lying or sitting position.\u00a0This often goes away on its own.\u00a0If not, contact your doctor.<\/p>\n\n\n\n<p>Common\u00a0side effects\u00a0(may affect up to 1 in 10 users) include changes in levels of\u00a0blood cells, blood lipids and, at the start of treatment, temporarily increased liver enzymes;\u00a0increased sugar levels in the blood and urine;\u00a0increased level of\u00a0uric acid\u00a0and\u00a0creatinine\u00a0phosphokinase in the blood;\u00a0increased appetite;\u00a0dizziness;\u00a0restlessness;\u00a0tremors;\u00a0movement difficulties (\u00a0dyskinesia\u00a0);\u00a0constipation;\u00a0dry mouth;\u00a0rash;\u00a0impotence;\u00a0extreme fatigue;\u00a0fluid retention leading to swelling of the hands, ankles or feet;\u00a0fever, joint pain and sexual problems such as reduced sex drive in men and women or erectile problems in men.<\/p>\n\n\n\n<p>Uncommon\u00a0side effects\u00a0(may affect up to 1 in 100 users) include hypersensitivity (eg swelling of the mouth and throat,\u00a0itching, rash);\u00a0diabetes\u00a0or worsening of diabetes, sometimes associated with\u00a0ketoacidosis\u00a0(ketones in the blood and urine) or coma;\u00a0convulsions, generally in case of a known tendency to convulsions (\u00a0epilepsy\u00a0);\u00a0muscle stiffness or\u00a0spasm (including eye movements);\u00a0crawling and feeling of restlessness in the legs when resting (restless legs);\u00a0speech difficulties;\u00a0stuttering;\u00a0slow heartbeat;\u00a0sun sensitivity;\u00a0nosebleed;\u00a0distended abdomen;\u00a0drooling;\u00a0memory loss or forgetfulness;\u00a0urinary incontinence;\u00a0difficulty urinating;\u00a0hair loss;\u00a0absent or shortened menstruation;\u00a0and breast changes in men and women such as abnormal production of breast milk or abnormal enlargement.<\/p>\n\n\n\n<p>Rare\u00a0side effects\u00a0(may affect up to 1 in 1,000 users) include lowering of the normal body temperature;\u00a0abnormal heart rhythm;\u00a0sudden, unexplained death;\u00a0inflammation\u00a0of the pancreas causing severe stomach pain, fever, and malaise;\u00a0liver disease manifesting as yellowing of the skin and whites of the eyes;\u00a0muscle disease manifesting in unexplained aches and pains;\u00a0and prolonged and\/or painful\u00a0erection.<\/p>\n\n\n\n<p>Very rare\u00a0side effects\u00a0include serious allergic reactions such as drug reactions with\u00a0eosinophilia\u00a0and systemic symptoms (DRESS).\u00a0DRESS presents initially with\u00a0flu-like symptoms\u00a0with a rash on the face and then by more widespread rash, fever, enlarged\u00a0lymph nodes, elevated levels of liver enzymes seen in blood tests, and elevated levels of a type of\u00a0white blood cell\u00a0(\u00a0eosinophils\u00a0).<\/p>\n\n\n\n<p>When taking medication with olanzapine, elderly patients with dementia may experience\u00a0a stroke,\u00a0pneumonia, urinary incontinence, increased tendency to fall, extreme fatigue, visual hallucinations, increased body temperature, skin redness, and difficulty walking.\u00a0Some deaths have been reported in this specific patient group.<\/p>\n\n\n\n<p>For patients with\u00a0Parkinson&#8217;s disease, ZYPREXA may worsen symptoms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">HOW TO STORE ZYPREXA<\/h2>\n\n\n\n<p>Store out of sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date stated on the carton.<\/p>\n\n\n\n<p>Store in the original packaging.&nbsp;Light sensitive.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>The medicine must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">PACKAGING CONTENTS AND OTHER INFORMATION<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is olanzapine.\u00a0Each tablet contains 2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg, or 20 mg of the active substance.\u00a0The exact amount is stated on your ZYPREXA packaging.<\/li><li>Other ingredients are;\u00a0Tablet core:\u00a0Lactose monohydrate, hypromellose, crospovidone, microcrystalline cellulose, and magnesium stearate.\u00a0Tablet coating: Hypromellose, titanium dioxide (E171), and carnauba wax.<\/li><li>The different tablet strengths also contain:<\/li><\/ul>\n\n\n\n<p><strong>TABLET STRENGTH, OTHER INGREDIENTS<\/strong><br>ZYPREXA 2.5 mg, 5 mg, 7.5 mg, and 10 mg tablets Tablet coating:<\/p>\n\n\n\n<p>Shellac, macrogol, propylene glycol, polysorbate 80 and indigo carmine dye (E132), anhydrous\u00a0ethanol, isopropyl alcohol, butyl alcohol, and ammonium hydroxide.<br><br>ZYPREXA 15 mg tablets Tablet coating: Triacetin and indigo carmine dye (E132)<br><br>ZYPREXA 20 mg tablets Tablet coating: Macrogol and\u00a0synthetic\u00a0red iron oxide (E172)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>ZYPREXA 2.5 mg&nbsp;coated&nbsp;tablets are white and debossed with \u201cLILLY\u201d and a numerical identification code \u201c4112\u201d.<\/p>\n\n\n\n<p>ZYPREXA 5 mg&nbsp;coated&nbsp;tablets are white and debossed with \u201cLILLY\u201d and a numerical identification code \u201c4115\u201d.<\/p>\n\n\n\n<p>ZYPREXA 7.5 mg&nbsp;coated&nbsp;tablets are white and debossed with \u201cLILLY\u201d and a numerical identification code \u201c4116\u201d.<\/p>\n\n\n\n<p>ZYPREXA 10 mg&nbsp;coated&nbsp;tablets are white and debossed with \u201cLILLY\u201d and a numerical identification code \u201c4117\u201d.<\/p>\n\n\n\n<p>ZYPREXA 15 mg&nbsp;coated&nbsp;tablets are blue.<\/p>\n\n\n\n<p>ZYPREXA 20 mg&nbsp;coated&nbsp;tablets are pink.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p>Eli Lilly Nederland BV, Papendorpseweg 83, 3528 BJ Utrecht, The Netherlands.<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Lilly SA, Avda.&nbsp;de la Industria 30, 28108 Alcobendas, Madrid, Spain.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>ZYPREXA contains the active substance olanzapine.\u00a0ZYPREXA belongs to the drug\u00a0group neuroleptics\u00a0and is used to treat the following conditions:<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22506],"tags":[10033,19677,19676,10034,28778,10035,28779,28777,28780,28781],"class_list":["post-38854","post","type-post","status-publish","format-standard","hentry","category-medicines","category-z","tag-olanzapine","tag-olanzapine-side-effects","tag-olanzapine-tablet","tag-what-is-olanzapine","tag-what-is-zyprexa","tag-what-olanzapine-is-used-for","tag-what-zyprexa-is-used-for","tag-zyprexa","tag-zyprexa-side-effects","tag-zyprexa-tablet"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/38854","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=38854"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/38854\/revisions"}],"predecessor-version":[{"id":39363,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/38854\/revisions\/39363"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=38854"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=38854"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=38854"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}