{"id":38284,"date":"2022-12-05T13:24:41","date_gmt":"2022-12-05T13:24:41","guid":{"rendered":"https:\/\/zeepedia.com\/?p=38284"},"modified":"2022-12-06T08:04:56","modified_gmt":"2022-12-06T08:04:56","slug":"zoriaxiol","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/zoriaxiol\/","title":{"rendered":"Zoriaxiol &#8211; Calcipotriol uses, dose and side effects"},"content":{"rendered":"\n<p>50 micrograms\/ml&nbsp;cutaneous&nbsp;solution<br>calcipotriol<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Zoriaxiol is and what it is used for<\/h2>\n\n\n\n<p>Zoriaxiol is used for local treatment of mild to moderately severe\u00a0scalp psoriasis.<\/p>\n\n\n\n<p>Psoriasis\u00a0is a disease where your skin cells are produced too quickly.\u00a0This causes skin flaking and\u00a0redness.\u00a0This solution helps restore the skin&#8217;s production rate of new cells to normal.<\/p>\n\n\n\n<p>Calcipotriol found in Zoriaxiol may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Zoriaxiol<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Zoriaxiol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to calcipotriol or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have severe liver or\u00a0kidney failure.<\/li><li>if you have problems with your\u00a0calcium\u00a0metabolism or if the calcium level in your body is too high.\u00a0This solution can increase the level of\u00a0calcium\u00a0in the blood.<\/li><li>if you simultaneously use other medicines that increase calcium levels.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Zoriaxiol.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>this solution may cause skin irritation.\u00a0If the solution accidentally gets on your face, wash it off immediately.\u00a0If it gets in the eye, rinse the eye with water.\u00a0Wash your hands after applying the solution.<\/li><li>if you use more than 60 ml of Zoriaxiol\u00a0cutaneous\u00a0solution during a week because you can develop high levels of\u00a0calcium\u00a0in the blood.\u00a0This can lead to e.g.\u00a0weakness, nausea, loss of appetite, and constipation (see also section 3).<\/li><li>if you are exposed to sunlight while using this solution.\u00a0All treatment with artificial UV radiation (including solarium) should first be discussed with your doctor.<\/li><li>if you know you have a type of\u00a0psoriasis\u00a0called generalized\u00a0pustular\u00a0or\u00a0erythrodermic\u00a0exfoliative\u00a0psoriasis.\u00a0Ask your doctor if you are unsure.<\/li><\/ul>\n\n\n\n<p>Do not apply the solution to the face, as it may cause skin irritation.<\/p>\n\n\n\n<p>Do not cover the treated area with a waterproof bandage.<\/p>\n\n\n\n<p>Avoid excessive exposure to sunlight when using the solution.<\/p>\n\n\n\n<p>Use Zoriaxiol with caution in skin folds, as this may increase the risk of\u00a0side effects.<\/p>\n\n\n\n<p>Zoriaxiol should not be used for guttate\u00a0psoriasis, erythrodermic\u00a0psoriasis,\u00a0or\u00a0pustular\u00a0psoriasis\u00a0as there is no experience.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Zoriaxiol<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are using, have recently used, or might be using other medicines.<\/p>\n\n\n\n<p>If you use this cutaneous solution together with other treatments for\u00a0psoriasis, your doctor will tell you when to use the solution.<\/p>\n\n\n\n<p>Concomitant use with systemic\u00a0vitamin\u00a0D preparations, calcium supplements, or other substances that can increase\u00a0serum\u00a0calcium concentration such as thiazide diuretics,\u00a0estrogens, anabolic\u00a0steroids,\u00a0and parathyroid hormone or parathyroid hormone analogs may increase the risk of you getting too high levels of\u00a0calcium\u00a0in the blood (clinically\u00a0significant\u00a0hypercalcemia\u00a0).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p><strong>Pregnancy<\/strong><\/p>\n\n\n\n<p>Zoriaxiol should not be used during pregnancy unless necessary.<\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p>It is not known whether calcipotriol passes into breast milk.&nbsp;Your doctor will decide if you can use Zoriaxiol during pregnancy and breastfeeding.<\/p>\n\n\n\n<p><strong>Fertility<\/strong><\/p>\n\n\n\n<p>There are no data on the effect of calcipotriol treatment on human\u00a0fertility.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>No effect on the ability to drive or use machines can be expected.\u00a0You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure<strong>.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Zoriaxiol contains 30 mg of propylene glycol per ml of solution.<\/h2>\n\n\n\n<p>Propylene glycol can cause skin irritation.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Zoriaxiol<\/h2>\n\n\n\n<p>Always use this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Dose<\/strong><\/p>\n\n\n\n<p><em><strong>Adults<\/strong><\/em><\/p>\n\n\n\n<p>You should not use more than 60 ml of this cutaneous solution in one week.<\/p>\n\n\n\n<p>If you use it together with a&nbsp;cream&nbsp;or ointment containing calcipotriol, the total amount of calcipotriol per week should not exceed 5 mg (eg 60 ml of scalp solution plus 40 g of&nbsp;cream&nbsp;or ointment).<\/p>\n\n\n\n<p><em>Method of use<\/em><\/p>\n\n\n\n<p>Zoriaxiol is intended for use on the scalp (\u00a0cutaneous\u00a0use).\u00a0Zoriaxiol should be used on the areas of the scalp affected by\u00a0psoriasis.<\/p>\n\n\n\n<p>When using the solution, tilt your head so that the solution does not run down your face.\u00a0It may help to part the hair before using the solution.\u00a0Remove the cap and run the nozzle down through the hair so that it reaches an affected area of \u200b\u200bthe scalp.\u00a0Gently press the bottle and apply a few drops.\u00a0Massage the solution gently.\u00a0One or two drops should cover an area about the size of a postage stamp.\u00a0If you accidentally get the solution on your face, wash it off immediately.\u00a0If you get the solution in your eyes, immediately rinse it out with water.\u00a0If you have access to some\u00a0sterile\u00a0saline solution, you can use it to rinse your eyes with afterward.\u00a0If the eyes still sting, you should consult a doctor.<\/p>\n\n\n\n<p>Wash your hands after applying this solution.<\/p>\n\n\n\n<p><em>How often should the application take place?<\/em><\/p>\n\n\n\n<p>For best results, you should apply this solution twice daily, once in the morning and once in the evening.<\/p>\n\n\n\n<p><em>Duration of treatment<\/em><\/p>\n\n\n\n<p>Your doctor decides how long the treatment should last, but normally it should not last longer than 22 weeks.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents (under 18 years)<\/h2>\n\n\n\n<p>Zoriaxiol is not recommended for children and adolescents (under 18 years of age) due to the lack of sufficient experience in the use of the solution among these patients.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have used too much Zoriaxiol<\/h2>\n\n\n\n<p>If you have used more solution than you should (more than 60 ml in a week), you should contact your doctor.\u00a0Such use can lead to high levels of\u00a0calcium\u00a0in the blood, which e.g.\u00a0can cause nausea, loss of appetite, constipation, vomiting, muscle weakness, weakness, fatigue, and unconsciousness.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child accidentally ingested the medicine, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Zoriaxiol<\/h2>\n\n\n\n<p>If you forget to use this solution at the right time, apply it as soon as you remember.\u00a0Then continue as before.\u00a0Do not apply more solutions than usual to make up for a missed\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Zoriaxiol<\/h2>\n\n\n\n<p>Always ask your doctor for advice if you are considering stopping treatment.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Stop using this cutaneous solution and consult a doctor or go to the nearest emergency department immediately if you experience any of the following symptoms:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Signs of\u00a0allergy\u00a0(less common\u00a0side effect\u00a0) such as\u00a0hives, swelling of the face, eyelids, hands, feet, or throat, or difficulty breathing.<\/li><\/ul>\n\n\n\n<p>Other possible side effects:<\/p>\n\n\n\n<p><strong>Very common&nbsp;side effects&nbsp;(<\/strong>&nbsp;may affect more than 1 in 10 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>skin irritation<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(<\/strong>&nbsp;may affect up to 1 in 10 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>itching<\/li><li>burning sensation in the skin<\/li><li>contact dermatitis<\/li><li>skin redness<\/li><li>worsened&nbsp;psoriasis<\/li><li>skin inflammation<\/li><li>flaky skin<\/li><li>skin rash (incl. scaly rash, papules and persistent pustules)<\/li><li>pain in the area where the drug is used.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(<\/strong>&nbsp;may affect up to 1 in 100 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dry skin<\/li><li>hypersensitivity\u00a0reaction<\/li><li>eczema, rash<\/li><li>changed skin color in the area where the medicine is used<\/li><li>folliculitis<\/li><li>hypercalciuria\u00a0(too much\u00a0calcium\u00a0in the urine)<\/li><li>hypercalcemia\u00a0(too much\u00a0calcium\u00a0in the blood)<\/li><li>dandruff (e.g. dandruff or\u00a0milk scab\u00a0)<\/li><li>transiently increased sensitivity to sunlight.<\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;(<\/strong>&nbsp;affects less than 1 in 1,000 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You may experience nausea, vomiting, loss of appetite, constipation, stomach pain, excessive thirst, muscle weakness, drowsiness, or confusion.<\/li><li>itchy raised rash (\u00a0hives\u00a0).<\/li><\/ul>\n\n\n\n<p>If you accidentally get the cutaneous solution on your face, it may cause&nbsp;redness&nbsp;or irritation on the face or around the mouth.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Zoriaxiol<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the bottle and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store at a maximum of 25 \u00b0C.&nbsp;<em>Store protected from cold.&nbsp;<\/em>Do not freeze.<\/p>\n\n\n\n<p>Store the bottle in the outer carton.&nbsp;Light sensitive.<\/p>\n\n\n\n<p>Do not use or store the cutaneous solution near open flames or flames (alcohol content is flammable).<\/p>\n\n\n\n<p>Shelf life after first opening: 3 months.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is calcipotriol.<br>One ml\u00a0of cutaneous\u00a0solution contains 0.05 mg (corresponding to 50 micrograms) of calcipotriol.<br>Other ingredients are sodium citrate, hypromellose, propylene glycol, isopropyl alcohol, levomenthol, and purified water.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>The clear, colorless solution that smells of menthol.<\/p>\n\n\n\n<p>The cutaneous solution is supplied in polyethylene bottles of 30 ml, 60 ml, 100 ml, and 120 ml.\u00a0The bottles have a polyethylene spout and are closed with polypropylene screw caps.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder:<\/em><\/p>\n\n\n\n<p>Sandoz A\/S, Edvard Thomsens Vej 14, 2300 Copenhagen S, Denmark<\/p>\n\n\n\n<p><em>Manufacturer:<\/em><\/p>\n\n\n\n<p>Lek Pharmaceuticals dd, Verov\u0161kova 57, 1526 Ljubljana, Slovenia<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Salutas Pharma GmbH, Otto-von-Guericke-Allee 1, 39179 Barleben, Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zoriaxiol is used for local treatment of mild to moderately severe\u00a0scalp psoriasis\u00a0.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22506],"tags":[28685,28689,4197,4198,8023,4199,28687,28686,28684,28688],"class_list":["post-38284","post","type-post","status-publish","format-standard","hentry","category-medicines","category-z","tag-benefits-of-calcipotriol","tag-benefits-of-zoriaxiol","tag-calcipotriol","tag-calcipotriol-side-effects","tag-what-calcipotriol-is-used-for","tag-what-is-calcipotriol","tag-what-is-zoriaxiol","tag-what-zoriaxiol-is-used-for","tag-zoriaxiol","tag-zoriaxiol-side-effects"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/38284","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=38284"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/38284\/revisions"}],"predecessor-version":[{"id":38605,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/38284\/revisions\/38605"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=38284"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=38284"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=38284"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}