{"id":38278,"date":"2022-12-05T13:23:19","date_gmt":"2022-12-05T13:23:19","guid":{"rendered":"https:\/\/zeepedia.com\/?p=38278"},"modified":"2022-12-06T08:04:59","modified_gmt":"2022-12-06T08:04:59","slug":"zopiclone-pilum","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/zopiclone-pilum\/","title":{"rendered":"Zopiclone Pilum &#8211; Zopiclone uses, dose and side effects"},"content":{"rendered":"\n<p>5 mg&nbsp;film-coated tablets<br>Zopiclone<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Zopiclone Pilum is and what it is used for<\/h2>\n\n\n\n<p>Zopiclone&nbsp;Pilum is a sleep aid that affects the centers in the brain that enable us to sleep.&nbsp;Zopiclone&nbsp;Pilum usually takes effect within 30 minutes.<\/p>\n\n\n\n<p>Zopiclone\u00a0Pilum is used for the treatment of various forms of sleep disorders, e.g.\u00a0difficulty falling asleep, early awakening, or many night awakenings in adults.\u00a0Zopiclone\u00a0Pilum is used for temporary and short-term sleep disorders and for a limited time for\u00a0chronic\u00a0sleep disorders in adults.<\/p>\n\n\n\n<p>The zopiclone contained\u00a0in\u00a0Zopiclone\u00a0Pilum may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Zopiclone Pilum<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Zopiclone Pilum<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to&nbsp;zopiclone&nbsp;or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have severe liver disease,<\/li><li>if you have the disease&nbsp;myasthenia gravis&nbsp;(muscle disease),<\/li><li>if you have pronounced breathing stops during sleep (&nbsp;sleep apnea&nbsp;),<\/li><li>if you have severely impaired breathing.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using\u00a0Zopiklon\u00a0Pilum:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have impaired liver function,<\/li><li>if you have impaired respiratory function,<\/li><li>if you are older,<\/li><li>if you have previously been addicted to drugs or alcohol.<\/li><\/ul>\n\n\n\n<p>Before starting treatment with&nbsp;Zopiclone&nbsp;Pilum, the cause of your sleep difficulties should be investigated and any other underlying disease treated.&nbsp;<\/p>\n\n\n\n<p><br>Zopiclone\u00a0Pilum can cause\u00a0dry mouth, which can increase the risk of tooth decay.\u00a0You should therefore be extra careful with dental hygiene.\u00a0Brushing with fluoride toothpaste twice a day is recommended.<\/p>\n\n\n\n<p><em>Addiction and withdrawal symptoms<\/em><\/p>\n\n\n\n<p>The use of drugs such as\u00a0Zopiclone\u00a0Pilum can lead to physical and psychological dependence.\u00a0The risk of addiction increases with\u00a0the dose\u00a0and duration of treatment.\u00a0The risk is also higher in patients who abuse or have abused alcohol or drugs and\/or have a pronounced personality disorder.<\/p>\n\n\n\n<p>If physical dependence occurs, a sudden interruption of the treatment may lead to withdrawal symptoms (see section 3 &#8220;If you stop taking\u00a0Zopiclone\u00a0Pilum&#8221;).<\/p>\n\n\n\n<p><em>Insomnia that returns after the end of treatment<\/em><\/p>\n\n\n\n<p>If the treatment is stopped suddenly after a long period of use, it sometimes leads to restless sleep for a few nights.\u00a0This is a temporary syndrome called &#8220;rebound insomnia&#8221;.\u00a0To avoid possible problems at termination after long-term treatment, it is recommended to gradually reduce the\u00a0dose.\u00a0See also the section dealing with\u00a0side effects.<\/p>\n\n\n\n<p><br><em>Tolerance development<\/em><\/p>\n\n\n\n<p>The effect of\u00a0Zopiclone\u00a0Pilum may decrease if the medicine is used repeatedly over several weeks.\u00a0This is called\u00a0tolerance development.\u00a0If you feel that the effect has decreased, talk to your doctor.<\/p>\n\n\n\n<p><br><em>Memory gaps, so-called anterograde&nbsp;amnesia<\/em><\/p>\n\n\n\n<p>Zopiclone\u00a0Pilum can cause short-term memory loss, especially a few hours after taking the tablet.\u00a0To reduce the risk of this, take\u00a0Zopiclone\u00a0Pilum just before or after you go to bed, and make sure you have an undisturbed sleep throughout the night.<\/p>\n\n\n\n<p><em><br>Psychic and &#8220;paradoxical&#8221; reactions<\/em><\/p>\n\n\n\n<p>When using\u00a0Zopiclone\u00a0Pilum, certain psychological reactions such as worry and anxiety, nightmares, irritability, aggressiveness, inappropriate behavior, hallucinations (seeing and hearing things that are not real), confusion, and difficulty concentrating may occur.<\/p>\n\n\n\n<p><em>Bedtime<\/em><\/p>\n\n\n\n<p>Sleepwalking and other similar behaviors, such as driving, cooking and eating, or making phone calls while asleep, without recalling the event afterward, have been reported in patients taking&nbsp;zopiclone&nbsp;who were not sufficiently awake.<\/p>\n\n\n\n<p>The risk of these behaviors increases:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if alcohol or certain other drugs (e.g. narcotics, pain relievers, antipsychotics, anxiolytic\/sedative drugs, or sleeping aids) are used during treatment with\u00a0Zopiclone\u00a0Pilum<\/li><li>if\u00a0Zopiclone\u00a0Pilum is used in higher\u00a0doses\u00a0than those recommended.<\/li><\/ul>\n\n\n\n<p>If you experience any of the above symptoms, contact your doctor immediately.&nbsp;Your doctor may decide to stop treatment with&nbsp;Zopiclone&nbsp;Pilum.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Zopiclone&nbsp;Pilum should not be used by children and adolescents under the age of 18.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Zopiclone Pilum<\/h2>\n\n\n\n<p>Some other medicines can affect or be affected by\u00a0Zopiclone\u00a0Pilum.\u00a0Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>The doctor needs to know if you are already being treated with:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>drugs for depression, anxiety, and insomnia (antidepressants,\u00a0anxiolytics,\u00a0hypnotics\u00a0)<\/li><li>medicines for certain mental illnesses (antipsychotics\/neuroleptics)<\/li><li>sedatives\u00a0_\u00a0_<\/li><li>narcotic pain-relieving drugs of the opioid type, e.g.\u00a0morphine and morphine-like substances<\/li><li>anesthetics\u00a0_\u00a0_<\/li><li>allergy\u00a0medicine\u00a0(\u00a0antihistamines\u00a0)<\/li><li>agents against\u00a0bacterial\u00a0and fungal infections containing erythromycin, itraconazole, and rifampicin<\/li><li>medicines used in the treatment of\u00a0epilepsy\u00a0that contain\u00a0phenytoin, phenobarbital, or carbamazepine<\/li><li>certain medicines used in the treatment of\u00a0HIV\u00a0infection,<\/li><li>herbal remedies containing\u00a0St. John&#8217;s wort.<\/li><\/ul>\n\n\n\n<p><br>Concomitant use of\u00a0Zopiclone\u00a0Pilum and opioid medicines (strong painkillers, medicines for the treatment of opioid dependence, and certain cough medicines) increases the risk of drowsiness, breathing difficulties (\u00a0respiratory depression\u00a0),\u00a0and coma\u00a0and can be life-threatening.\u00a0Because of this, concomitant use should only be considered when other treatment options are not possible.<\/p>\n\n\n\n<p><br>If the doctor prescribes&nbsp;Zopiklon&nbsp;Pilum at the same time as opioid drugs,&nbsp;dose&nbsp;one and<\/p>\n\n\n\n<p>the treatment time is limited by the doctor.<\/p>\n\n\n\n<p><br>Tell your doctor if you are taking any opioid medication and follow your doctor&#8217;s dosage recommendations carefully.&nbsp;It may be helpful to inform friends or relatives to be aware of the signs and symptoms described above.&nbsp;Contact a doctor if you experience any of these symptoms.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Zopiclone Pilum with food, drink, and alcohol<\/h2>\n\n\n\n<p>Alcohol should be avoided when using\u00a0Zopiclone\u00a0Pilum as alcohol can increase the effect of\u00a0Zopiclone\u00a0Pilum.\u00a0The effect may persist until the next morning, which may hurt your ability to drive or operate machinery.<\/p>\n\n\n\n<p>Grapefruit and grapefruit juice should be avoided while taking&nbsp;Zopiclone&nbsp;Pilum.&nbsp;Grapefruit may increase the effect of&nbsp;Zopiclone&nbsp;Pilum.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>You should not take\u00a0Zopiclone\u00a0Pilum if you are pregnant.\u00a0If\u00a0Zopiclone\u00a0Pilum is taken during the last three months of pregnancy or childbirth, there is a risk that the newborn baby will be affected.\u00a0Symptoms of impact on the child include low\u00a0blood pressure\u00a0(\u00a0hypotension\u00a0), impact on breathing, and low body temperature.<\/p>\n\n\n\n<p><em><br>Breast-feeding<\/em><\/p>\n\n\n\n<p>Zopiclone&nbsp;Pilum should not be taken during breastfeeding.&nbsp;Zopiclone&nbsp;Pilum passes into breast milk.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>You should not drive or operate machinery until your treatment with&nbsp;Zopiclone&nbsp;Pilum has finished, or until it has been established that your ability is not impaired.&nbsp;The effect can also last until the following day.<\/p>\n\n\n\n<p>Side effects&nbsp;of&nbsp;Zopiclone&nbsp;Pilum that may affect your ability to drive are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fatigue and drowsiness the following day (residual&nbsp;somnolence&nbsp;)<\/li><li>Dizziness<\/li><li>Memory gaps (anterograde&nbsp;amnesia&nbsp;)<\/li><li>Impaired ability to concentrate<\/li><\/ul>\n\n\n\n<p>The risk of you suffering from the above&nbsp;side effects&nbsp;is greater if you have drunk alcohol and if you have not had enough sleep.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Zopiclone Pilum contains lactose<\/h2>\n\n\n\n<p>Zopiclone\u00a0Pilum contains\u00a0lactose.\u00a0If you have an intolerance to certain sugars, you should consult your doctor before taking this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Zopiclone Pilum<\/h2>\n\n\n\n<p>Always use this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><br>The dose&nbsp;and duration of treatment must be determined by the doctor who adapts it individually for you.&nbsp;The duration of treatment should be as short as possible and the treatment should be phased out gradually.<\/p>\n\n\n\n<p><br>The recommended\u00a0dose\u00a0for adults: One tablet of 5 mg or 7.5 mg at bedtime.<\/p>\n\n\n\n<p><br>The recommended\u00a0dose\u00a0for the elderly is half a tablet\u00a0of Zopiclone\u00a0Pilum 7.5 mg, which corresponds to 3.75 mg\u00a0of zopiclone.\u00a0The doctor may then increase the\u00a0dose\u00a0to 5 mg or 7.5 mg.<\/p>\n\n\n\n<p><br>If you have reduced kidney function, you should start the treatment with half a tablet\u00a0of Zopiclone\u00a0Pilum 7.5 mg, which is equivalent to 3.75 mg\u00a0of zopiclone.<\/p>\n\n\n\n<p><br>If you have impaired liver function or\u00a0chronic\u00a0respiratory insufficiency\u00a0(respiratory failure), you should start the treatment with half a tablet\u00a0of Zopiclone\u00a0Pilum 7.5 mg, which corresponds to 3.75 mg\u00a0of zopiclone.\u00a0Dose\u00a0one can later be increased to 5 mg and if necessary up to 7.5 mg.<\/p>\n\n\n\n<p><br>Since the tablets usually work within half an hour, it is important to take them at bedtime or only when a natural fall asleep has not occurred.&nbsp;To get the effect quickly, the tablets should be taken in an upright position together with 1\/2 glass of water.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Zopiclone&nbsp;Pilum should not be given to children and adolescents under 18 years of age.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Zopiclone Pilum<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has accidentally ingested the medicine, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Zopiclone Pilum<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<br><br>If you are still able to sleep undisturbed for a whole night, take the missed\u00a0dose\u00a0right away.\u00a0If you are unable to get a full night&#8217;s sleep, skip the missed\u00a0dose\u00a0and do not take another\u00a0dose\u00a0until you go to bed the following evening.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Zopiclone Pilum<\/h2>\n\n\n\n<p>If you suddenly stop taking\u00a0Zopiclone\u00a0Pilum, your sleep problems may return for a temporary period.\u00a0You may also experience withdrawal symptoms.\u00a0Withdrawal symptoms include difficulty sleeping, headaches, sweating, hallucinations, and increased heart rate.\u00a0In more serious and very rare cases, convulsions may occur.\u00a0<\/p>\n\n\n\n<p><br>The risk of withdrawal symptoms increases with the\u00a0dose\u00a0and the duration of treatment, and therefore the doctor can give you information on how to gradually reduce the\u00a0dose.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Contact a doctor immediately if the following serious&nbsp;side effects&nbsp;occur:<\/strong><\/p>\n\n\n\n<p>Stop taking\u00a0Zopiclone\u00a0Pilum and contact a doctor immediately if you experience a severe\u00a0allergic reaction\u00a0with any of the following symptoms (\u00a0angioedema, anaphylactic\u00a0shock\u00a0) (rare side effects: may occur in up to 1 in 1,000 users):<\/p>\n\n\n\n<p>&#8211; swelling of the face, tongue, or throat<\/p>\n\n\n\n<p>&#8211; difficulty swallowing<\/p>\n\n\n\n<p>&#8211;&nbsp;hives&nbsp;and difficulty breathing<\/p>\n\n\n\n<p>&#8211; drop in blood pressure<\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;may occur:<\/strong><\/p>\n\n\n\n<p><strong>Common\u00a0side effects\u00a0(\u00a0<\/strong><em>may affect up to 1 in 10 users)<\/em>:\u00a0Dry mouth, bitter\/metallic taste in the mouth (often transient).\u00a0Drowsiness, which is dependent on the size of the dose.<\/p>\n\n\n\n<p><strong>Uncommon\u00a0side effects\u00a0(\u00a0<\/strong><em>may affect up to 1 in 100 users)<\/em>: Headache, nightmares, nausea, restlessness, dizziness.<\/p>\n\n\n\n<p><strong>Rare\u00a0side effects\u00a0(\u00a0<\/strong><em>may affect up to 1 in 1,000 users)<\/em>: Somnolence, anxiety, aggressiveness, irritability, inappropriate behavior possibly associated with memory lapses, hallucinations, confusion, and difficulty concentrating.\u00a0Stomach upset (\u00a0dyspepsia\u00a0).\u00a0Skin rash,\u00a0itching, hives.\u00a0Effect on liver enzymes.<\/p>\n\n\n\n<p><br>If you stop the treatment suddenly after long-term treatment, so-called withdrawal symptoms may occur.\u00a0Examples of such symptoms can be insomnia, nightmares, headaches, tremors, sweating, confusion (\u00a0delirium\u00a0), hallucinations, palpitations, and increased heart rate.\u00a0You may also feel anxious, irritated, and upset.\u00a0In very rare cases, convulsions have also occurred.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Zopiclone Pilum<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Store at a maximum of 25 \u00b0C.<\/p>\n\n\n\n<p>Store in the original packaging.&nbsp;Light sensitive and moisture sensitive.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is\u00a0zopiclone.\u00a0One tablet contains 5 mg\u00a0of zopiclone.<\/li><li>Other ingredients are:<\/li><\/ul>\n\n\n\n<p><em>Tablet core:<\/em>&nbsp;anhydrous calcium hydrogen phosphate, potato starch, magnesium stearate,&nbsp;colloidal&nbsp;hydrated silicon dioxide, sodium starch glycolate.<\/p>\n\n\n\n<p><em>The film coating:<\/em>\u00a0hypromellose, titanium dioxide (E 171),\u00a0lactose monohydrate, macrogol, and triacetin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p><em>Appearance<\/em><\/p>\n\n\n\n<p>White, round, film-coated biconvex tablet.&nbsp;Diameter 6 mm.<\/p>\n\n\n\n<p><em>Package sizes<\/em><\/p>\n\n\n\n<p>Blisters: 10, 30, or 100 tablets.<\/p>\n\n\n\n<p>Plastic jar 250 or 500 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder<\/em><\/p>\n\n\n\n<p>Pilum Pharma A\/S, Energivej 15, 5260 Odense S, Denmark<\/p>\n\n\n\n<p><em>Local Representative<\/em><\/p>\n\n\n\n<p>Orifarm Generics AB, Box 56048, 102 17 Stockholm,&nbsp;<a href=\"http:\/\/mailto:info@orifarm.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">info@orifarm.com<\/a><\/p>\n\n\n\n<p><em>Manufacturer<\/em><\/p>\n\n\n\n<p>AS Grindeks, Krustpils iela 53, LV-1057 R\u012bga, Latvia<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zopiclone\u00a0Pilum is a sleep aid that affects the centers in the brain that enable us to sleep.\u00a0Zopiclone\u00a0Pilum usually takes effect within 30 minutes.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22506],"tags":[12963,28696,12959,28693,28690,28694,12958,28692,28695,28691],"class_list":["post-38278","post","type-post","status-publish","format-standard","hentry","category-medicines","category-z","tag-benefits-of-zopiclone","tag-benefits-of-zopiclone-pilum","tag-what-is-zopiclone","tag-what-is-zopiclone-pilum","tag-what-zopiclone-is-used-for","tag-what-zopiclone-pilum-is-used-for","tag-zopiclone","tag-zopiclone-pilum","tag-zopiclone-pilum-side-effects","tag-zopiclone-side-effects"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/38278","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=38278"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/38278\/revisions"}],"predecessor-version":[{"id":38607,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/38278\/revisions\/38607"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=38278"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=38278"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=38278"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}