{"id":36451,"date":"2022-11-28T07:40:55","date_gmt":"2022-11-28T07:40:55","guid":{"rendered":"https:\/\/zeepedia.com\/?p=36451"},"modified":"2022-11-29T10:16:52","modified_gmt":"2022-11-29T10:16:52","slug":"zoledronic-acid-hospira","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/zoledronic-acid-hospira\/","title":{"rendered":"Zoledronic Acid Hospira &#8211; Zoledronic acid uses, dose and side effects"},"content":{"rendered":"\n<p>4 mg\/100 ml\u00a0infusion fluid, solution<br>zoledronic acid<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Zoledronic Acid Hospira is and what it is used for<\/h2>\n\n\n\n<p>The active substance in Zoledronic Acid Hospira is zoledronic acid which belongs to a group of substances called bisphosphonates.&nbsp;Zoledronic acid works by binding to bone tissue and reducing the rate of bone turnover.&nbsp;It is used for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>To prevent bone complications<\/strong>, e.g.\u00a0fractures, in adult patients with bone metastases (cancer that has spread from the primary cancer site to bone tissue).<\/li><li>To reduce the amount of\u00a0calcium\u00a0in the blood in adult patients when this is too high due to a\u00a0tumor.\u00a0Tumors\u00a0can accelerate the normal rate of bone turnover in such a way that the\u00a0release\u00a0of\u00a0calcium\u00a0from the bone tissue increases.\u00a0This condition is called tumor-induced\u00a0hypercalcemia\u00a0(TIH).<\/li><\/ul>\n\n\n\n<p><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you receive Zoledronic Acid Hospira<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Zoledronic Acid Hospira<\/h2>\n\n\n\n<p>Just follow the instructions you have been given by your doctor.<\/p>\n\n\n\n<p>Your doctor will take blood tests before you start treatment with Zoledronic Acid Hospira and will regularly monitor how you respond to treatment.<\/p>\n\n\n\n<p><strong>You should not receive Zoledronic Acid Hospira:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are breastfeeding.<\/li><li>if you are allergic to zoledronic acid, other bisphosphonates (the group of substances to which zoledronic acid belongs), or to any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor before receiving Zoledronic Acid Hospira:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have or have had any kidney disease.<\/li><li>if you or have had pain, swelling, or numbness in the jaw, a feeling of &#8220;heavy jaw&#8221; or that a tooth has become loose.\u00a0Your doctor may recommend that you undergo a dental examination before starting treatment with Zoledronic Acid Hospira.<\/li><li>if you are undergoing dental treatment or are going to undergo dental surgery, inform your dentist that you are being treated with Zoledronic Acid Hospira and inform your doctor about your dental treatment.<\/li><\/ul>\n\n\n\n<p>While you are being treated with Zoledronic Acid Hospira, you should maintain good oral hygiene (including regular tooth brushing) and have regular dental check-ups.<\/p>\n\n\n\n<p>Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, pain or swelling, or sores that do not heal or drain, as these may be signs of a condition called&nbsp;osteonecrosis&nbsp;of the jaw.<\/p>\n\n\n\n<p>Patients who are receiving\u00a0chemotherapy\u00a0and\/or radiation therapy, who are taking\u00a0steroids, who are undergoing dental surgery, who do not receive regular dental care, who have gum problems, who are smokers, or who have previously been treated with bisphosphonates (used to treat or prevent bone disease) may have a higher risk of developing\u00a0osteonecrosis\u00a0of the jaw.<\/p>\n\n\n\n<p>Decreased levels of calcium in the blood (hypocalcemia) which can sometimes lead to muscle cramps, dry skin, and a burning sensation have been reported in patients treated with zoledronic acid.\u00a0Irregular heart rhythm (\u00a0cardiac arrhythmia\u00a0), convulsions,\u00a0spasms, and twitching (\u00a0tetany\u00a0) have been reported as a result of severe\u00a0hypocalcemia.\u00a0In some cases,\u00a0hypocalcemia\u00a0can be life-threatening.\u00a0If any of these occur, talk to your doctor immediately.\u00a0If you have existing\u00a0hypocalcemia, it must be corrected before starting the first\u00a0dose\u00a0of Zoledronic Acid Hospira.\u00a0You will be given adequate supplements of\u00a0calcium\u00a0and vitamin D.<\/p>\n\n\n\n<p><strong>Patients who are 65 years of age and older<\/strong><\/p>\n\n\n\n<p>Zoledronic Acid Hospira can be given to people aged 65 and over.&nbsp;There is nothing to suggest that any extra precautions would be necessary.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Zoledronic Acid Hospira is not recommended for use in adolescents and children under 18 years of age.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Zoledronic Acid Hospira<\/h2>\n\n\n\n<p>Tell your doctor if you are taking or have recently taken any other medicines, including those obtained without a prescription.\u00a0You must tell your doctor if you are also taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Aminoglycosides\u00a0(medicines used to treat serious\u00a0infections\u00a0), calcitonin (a type of medicine used to treat osteoporosis in postmenopausal women and\u00a0hypercalcemia), loop diuretics (a type of medicine used to treat high\u00a0blood pressure\u00a0or swelling caused by fluid retention (edema) or other medicines that lower calcium levels, as these in combination with bisphosphonates can have the effect of lowering the calcium level in the blood to an excessively low level.<\/li><li>Thalidomide (a medicine used to treat a certain type of blood cancer involving bone tissue) or any other medicine that can damage the kidneys.<\/li><li>Any other medicine that also contains zoledronic acid is used to treat\u00a0osteoporosis\u00a0or any other non-cancerous disease of bone tissue, or any other bisphosphonate, as the effects of combining these medicines with Zoledronic Acid Hospira are unknown.<\/li><li>Anti-angiogenic medicines (used to treat cancer), as combining these with Zoledronic Acid Hospira have been associated with an increased risk of bone damage (\u00a0osteonecrosis\u00a0) of the jaw (ONJ).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>You should not be treated with Zoledronic Acid Hospira if you are pregnant.&nbsp;Inform your doctor if you think you are pregnant.<\/p>\n\n\n\n<p>You must not be treated with Zoledronic Acid Hospira if you are breastfeeding.<\/p>\n\n\n\n<p>Consult a doctor or pharmacist before taking any medicine during the period that you are pregnant or breastfeeding.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>There have been very rare cases of lethargy and sleepiness associated with the use of Zoledronic Acid Hospira.\u00a0You should therefore be careful when driving a car, using machines, or performing other activities that require your full concentration.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Zoledronic Acid Hospira contains sodium<\/h2>\n\n\n\n<p>This medicine contains 360 mg of&nbsp;sodium&nbsp;(the main ingredient in common\/table salt) per dose unit.&nbsp;This corresponds to 18% of the maximum recommended daily intake of&nbsp;sodium&nbsp;for adults.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to get Zoledronic Acid Hospira<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Zoledronic Acid Hospira should only be given by healthcare professionals who are experienced in the\u00a0administration\u00a0of bisphosphonates\u00a0intravenously, i.e.\u00a0through a vein.<\/li><li>Your doctor will recommend that you drink enough water before each treatment to help prevent dehydration.<\/li><li>Carefully follow all other instructions from your doctor, pharmacist, or nurse.<\/li><\/ul>\n\n\n\n<p><strong>What&nbsp;dose&nbsp;of Zoledronic Acid Hospira is given?<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The single dose that is usually given is 4 mg.<\/li><li>If you have impaired kidney function, your doctor will give you a lower\u00a0dose, which depends on the severity of your kidney problems.<\/li><\/ul>\n\n\n\n<p><strong>How often will you be treated with Zoledronic Acid Hospira?<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are being treated for the prevention of bone tissue complications due to&nbsp;metastases&nbsp;in the bone tissue, you will receive an&nbsp;infusion&nbsp;of Zoledronic Acid Hospira every three to four weeks.<\/li><li>If you are being treated to reduce the amount of&nbsp;calcium&nbsp;in your blood, you will normally only receive one&nbsp;infusion&nbsp;of Zoledronic Acid Hospira.<\/li><\/ul>\n\n\n\n<p><strong>How is Zoledronic Acid Hospira given?<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Zoledronic Acid Hospira is given as a drip (&nbsp;infusion&nbsp;) into a vein over at least 15 minutes and must be given&nbsp;intravenously&nbsp;as a separate&nbsp;infusion&nbsp;in a special infusion tube.<\/li><\/ul>\n\n\n\n<p>Patients who do not have too much&nbsp;calcium&nbsp;in their blood will also receive a prescription for&nbsp;calcium&nbsp;and&nbsp;vitamin&nbsp;D supplements, which must be taken daily.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you receive too much Zoledronic Acid Hospira<\/h2>\n\n\n\n<p>If you have received\u00a0doses\u00a0higher than those recommended, you must be carefully examined by your doctor.\u00a0This is because you may have abnormal amounts of\u00a0electrolytes\u00a0in your blood (eg abnormal amounts of\u00a0calcium, phosphorus, and\u00a0magnesium\u00a0) and\/or changes in kidney function, including severely impaired kidney function.\u00a0If your level of\u00a0calcium\u00a0is too low, you may need to receive additional\u00a0calcium\u00a0by\u00a0infusion.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.\u00a0The most common of these are usually mild and will most likely disappear after a short time.<\/p>\n\n\n\n<p><strong>Tell your doctor immediately if you experience any of the following serious side effects:<\/strong><\/p>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe kidney impairment (normally determined by your doctor using some specific blood tests).<\/li><li>Low levels of&nbsp;calcium&nbsp;in the blood.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pain in the mouth, teeth, and\/or jaw, swelling or sores that do not heal on the inside of the mouth or jaw, warts, numbness, or a feeling of the heavy jaw or\u00a0tooth loss.\u00a0These may be signs of bone damage in the jaw (\u00a0osteonecrosis\u00a0).\u00a0Tell your doctor and dentist immediately if you experience such symptoms while you are being treated with Zoledronic Acid Hospira or after stopping treatment.<\/li><li>Irregular heart rhythm (\u00a0atrial fibrillation\u00a0) has been observed in patients receiving zoledronic acid for postmenopausal\u00a0osteoporosis.\u00a0It is currently unclear whether zoledronic acid causes this irregular heart rhythm but you should report it to your doctor if you experience such symptoms after receiving zoledronic acid.<\/li><li>Severe allergic reaction: shortness of breath, swelling mainly of the face and throat.<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>As a result of low calcium levels: irregular heart rhythm (cardiac arrhythmia; as a result of&nbsp;hypocalcemia&nbsp;).<\/li><li>A kidney function disorder called Fanconi syndrome (normally diagnosed by your doctor with urine samples).<\/li><\/ul>\n\n\n\n<p><strong>Very rare (may affect up to 1 in 10,000 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>As a result of low calcium levels: convulsions, numbness, and twitching (as a result of\u00a0hypocalcemia).<\/li><li>Talk to your doctor if you have ear pain, discharge from the ear, and\/or an ear infection.\u00a0This could be a sign of a bone injury in the ear.<\/li><li>Osteonecrosis\u00a0has, in very rare cases, also been observed in bones other than the jaw, especially in the hip or thigh.\u00a0Tell your doctor immediately if you experience symptoms such as new or worsening aches, pains, or stiffness during treatment with Zoledronic Acid Hospira or after stopping treatment.<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor as soon as possible if you experience any of the following side effects:<\/strong><\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 in 10 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Low level of&nbsp;phosphate&nbsp;in the blood.<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache and a flu-like condition consisting of fever, fatigue, weakness, drowsiness, chills, and aches in bones, joints, and\/or muscles.\u00a0In most cases, no treatment is required and the symptoms disappear after a short time (a few hours or days).<\/li><li>Reactions from the gastrointestinal tract, e.g.\u00a0nausea and vomiting and loss of appetite.<\/li><li>Inflammation\u00a0in the\u00a0conjunctiva\u00a0of the eye.<\/li><li>Low level of\u00a0red blood cells\u00a0(\u00a0anemia\u00a0).<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hypersensitivity reaction.<\/li><li>Low\u00a0blood pressure.<\/li><li>Chest pain.<\/li><li>Skin reactions (\u00a0redness\u00a0and swelling) at the infusion site, rash,\u00a0itching.<\/li><li>High\u00a0blood pressure, shortness of breath, dizziness, anxiety, sleep disturbances, changes in taste, tremors, tingling or numbness in the hands and feet, diarrhea, constipation, stomach pain,\u00a0and dry mouth.<\/li><li>A low number of\u00a0white blood cells\u00a0and\u00a0platelets.<\/li><li>The low blood level of\u00a0magnesium\u00a0and\u00a0potassium.\u00a0Your doctor will check this and take the necessary measures.<\/li><li>Weight gain.<\/li><li>Increased sweating.<\/li><li>Somnolence.<\/li><li>Blurred vision, watery eyes, eye sensitivity to light.<\/li><li>A sudden feeling of coldness with fainting, weakness, or collapse.<\/li><li>Difficulty breathing with wheezing or coughing.<\/li><li>Hives.<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Slow\u00a0pulse.<\/li><li>Confusion.<\/li><li>Unusual femur fractures, especially in patients receiving long-term treatment for osteoporosis, may occur in rare cases.\u00a0Contact your doctor if you experience pain, weakness, or discomfort in the thigh, hip, or groin as this may be an early sign of a possible femur fracture.<\/li><li>Interstitial lung disease (\u00a0inflammation\u00a0of\u00a0the tissue\u00a0around the air sacs in the lungs)<\/li><li>Flu-like symptoms\u00a0include\u00a0arthritis\u00a0and joint swelling.<\/li><li>Painful red and\/or swollen eyes.<\/li><\/ul>\n\n\n\n<p><strong>Very rare (may affect up to 1 in 10,000 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fainting due to low\u00a0blood pressure.<\/li><li>Severe pain in bones, joints, and\/or muscles, which in some cases can be disabling.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Zoledronic Acid Hospira<\/h2>\n\n\n\n<p>Your doctor, pharmacist, or nurse knows how to store Zoledronic Acid Hospira correctly (see section 6).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance in Zoledronic Acid Hospira 4 mg\/100 ml solution for\u00a0infusion\u00a0is zoledronic acid.\u00a0Each 100 ml sachet contains 4 mg zoledronic acid (as monohydrate).<\/li><li>One ml of solution contains 0.04 mg zoledronic acid (as monohydrate).<\/li><li>Other ingredients are: mannitol, sodium citrate, sodium chloride, and water for injections (see section 2, Zoledronic Acid Hospira 4 mg\/100 ml\u00a0solution for infusion\u00a0contains\u00a0sodium\u00a0)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Zoledronic Acid Hospira is a clear and colorless solution.\u00a0It is supplied in plastic bags of 100 ml as a ready-to-use solution for\u00a0infusion.<\/p>\n\n\n\n<p>Each pack contains one sachet containing 4 mg of zoledronic acid.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Pfizer Europe MA EEIG<\/p>\n\n\n\n<p>Boulevard de la Plaine 17<\/p>\n\n\n\n<p>1050 Brussels<\/p>\n\n\n\n<p>Belgium<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Pfizer Service Company BVBA<\/p>\n\n\n\n<p>Hoge Wei 10<\/p>\n\n\n\n<p>1930 Zaventem<\/p>\n\n\n\n<p>Belgium<\/p>\n\n\n\n<p>Contact the representative of the Marketing Authorization Holder if you would like to know more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>BE\/LU<\/strong>Pfizer NV\/Satel\/Tel: +32 (0) 2 554 62 11<\/td><td><b>Pfizer<\/b> Luxembourg SARL branches in LithuaniaTel.\u00a0+ 370 52 51 4000<\/td><\/tr><tr><td><strong>BG<\/strong>Pfizer Luxembourg \u0421\u0410\u0420\u041b, \u041a\u043b\u043e\u043d \u0411\u0443\u043b\u0433\u0430\u0440\u0438\u044fTel.: +359 2 970 4333<\/td><td>&nbsp;<\/td><\/tr><tr><td><strong>CZ<\/strong>Pfizer, coil.\u00a0s iPhone: +420-283-004-111<\/td><td><b>Pfizer<\/b> Kft.Phone: + 36 1 488 37 00<\/td><\/tr><tr><td><strong>DK<\/strong>Pfizer ApSTel: + 45 44 20 11 00<\/td><td><strong>MT<\/strong>Drugsales LtdPhone: +356 21 419 070\/1\/2<\/td><\/tr><tr><td><strong>THE<\/strong>PFIZER PHARMA GmbHPhone: +49 (0)30 550055-51000<\/td><td><strong>NL<\/strong>Pfizer by phone: +31 (0)10 406 43 01<\/td><\/tr><tr><td><b>Pfizer<\/b> Luxembourg SARL Eesti branch phone: +372 666 7500<\/td><td><b>Pfizer<\/b> iPhone: +47 67 52 61 00<\/td><\/tr><tr><td><b>Pfizer<\/b> \u0395\u039b\u039b\u0391\u03a3 AETel.: +30 210 6785 800<\/td><td><b>Pfizer<\/b> Corporation Austria Ges.mbHPhone: +43 (0)1 521 15-0<\/td><\/tr><tr><td><b>Pfizer<\/b>, SLPhone: +34 91 490 99 00<\/td><td><strong>PL<\/strong>Pfizer Polska Sp.\u00a0z o. iPhone: +48 22 335 61 00<\/td><\/tr><tr><td><strong>FR<\/strong>PfizerTel: + 33 (0)1 58 07 34 40<\/td><td><strong>PT<\/strong>Laborat\u00f3rios Pfizer, Lda.Phone: +351 21 423 55 00<\/td><\/tr><tr><td><b>Pfizer<\/b> Croatia dooPhone: +385 1 3908 777<\/td><td><strong>ROCK<\/strong>Pfizer Rom\u00e2nia SRLPhone: +40 (0)21 207 28 00<\/td><\/tr><tr><td><b>Pfizer<\/b> Healthcare IrelandPhone: 1800 633 363 (toll-free)+44 (0) 1304 616161<\/td><td><b>Pfizer<\/b> Luxembourg SARLPfizer, a branch of marketing, LjubljanaPhone: +386 (0)1 52 11 400<\/td><\/tr><tr><td><strong>IS<\/strong>Icepharma hf.Telephone: +354 540 8000<\/td><td><strong>SK<\/strong>Pfizer Luxembourg SARL, organiza\u010dn\u00e1 zlo\u017ekaPhone: +421\u20132\u20133355 5500<\/td><\/tr><tr><td><strong>IT<\/strong>Pfizer SrlPhone: +39 06 33 18 21<\/td><td><strong>FI<\/strong>Pfizer OyPhone\/Tel: +358 (0)9 430 040<\/td><\/tr><tr><td><strong>CY<\/strong>Pharmaceutical Trading Co LtdPhone: 24656165<\/td><td><strong>SEE<\/strong>Pfizer ABPhone: +46 (0)8 550 520 00<\/td><\/tr><tr><td><strong>LV<\/strong>Pfizer Luxembourg SARL branch in LatviaTel.: + 371 670 35 775<\/td><td><strong>UK (Northern Ireland)<\/strong>Pfizer LimitedTel: + 44 (0) 1304 616161<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>The active substance in Zoledronic Acid Hospira is zoledronic acid which belongs to a group of substances called bisphosphonates.\u00a0Zoledronic acid works by binding to bone tissue and reducing the rate of bone turnover.\u00a0It is used for:<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22506],"tags":[11834,28545,11832,28542,28543,11833,11831,28541,28544,28406],"class_list":["post-36451","post","type-post","status-publish","format-standard","hentry","category-medicines","category-z","tag-benefits-of-zoledronic-acid","tag-benefits-of-zoledronic-acid-hospira","tag-what-is-zoledronic-acid","tag-what-is-zoledronic-acid-hospira","tag-what-zoledronic-acid-hospira-is-used-for","tag-what-zoledronic-acid-is-used-for","tag-zoledronic-acid","tag-zoledronic-acid-hospira","tag-zoledronic-acid-hospira-side-effects","tag-zoledronic-acid-side-effects"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/36451","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=36451"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/36451\/revisions"}],"predecessor-version":[{"id":36662,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/36451\/revisions\/36662"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=36451"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=36451"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=36451"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}