{"id":35116,"date":"2022-11-22T07:40:38","date_gmt":"2022-11-22T07:40:38","guid":{"rendered":"https:\/\/zeepedia.com\/?p=35116"},"modified":"2022-11-24T08:07:20","modified_gmt":"2022-11-24T08:07:20","slug":"zinforo","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/zinforo\/","title":{"rendered":"Zinforo &#8211; Ceftaroline fosamilum uses, dose and side effects"},"content":{"rendered":"\n<p>600 mg\u00a0powder for concentrate for\u00a0infusion, solution<br>ceftaroline fosamilum (ceftaroline fosamilum)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Zinforo is and what it is used for<\/h2>\n\n\n\n<p><strong>What Zinforo is<\/strong><\/p>\n\n\n\n<p>Zinforo is an antibiotic medicine containing the active substance ceftarolinefosamil.&nbsp;It belongs to a group of medicines called &#8220;cephalosporin antibiotics&#8221;.<\/p>\n\n\n\n<p><strong>What Zinforo is used for<\/strong><\/p>\n\n\n\n<p>Zinforo is used to treat children (from birth) and adults with the following diseases:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>infection\u00a0in the skin and the\u00a0tissues\u00a0under the skin<\/li><li>an\u00a0infection\u00a0in the lungs called\u00a0pneumonia\u00a0or\u00a0pneumonia<\/li><\/ul>\n\n\n\n<p><strong>How Zinforo works<\/strong><\/p>\n\n\n\n<p>Zinforo works by killing certain bacteria that can cause serious\u00a0infections.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Zinforo<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Zinforo<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to ceftarolinefosamil or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you are allergic to other cephalosporin antibiotics<\/li><li>if you have previously had severe allergic reactions to other&nbsp;antibiotics&nbsp;such as&nbsp;penicillin&nbsp;or carbapenems<\/li><\/ul>\n\n\n\n<p>Do not use Zinforo if any of the above applies to you.&nbsp;If you are not sure, talk to your doctor or nurse before using Zinforo.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before using Zinforo:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have kidney problems (your doctor may need to&nbsp;prescribe&nbsp;a lower&nbsp;dose&nbsp;)<\/li><li>if you have ever had seizures (convulsions)<\/li><li>if you have ever had mild allergic reactions to other&nbsp;antibiotics&nbsp;such as&nbsp;penicillin&nbsp;or carbapenems<\/li><li>if you have ever had severe diarrhea while taking&nbsp;antibiotics<\/li><\/ul>\n\n\n\n<p>You may get an&nbsp;infection&nbsp;caused by another&nbsp;bacteria&nbsp;during or after treatment with Zinforo.<\/p>\n\n\n\n<p>You may develop signs and symptoms of serious skin reactions such as fever, joint pain, rash, red scaly skin, blisters, blisters or peeling skin, red round spots on the upper body, often with blisters in the middle, sores in the mouth, throat, nose, genitals or eyes.&nbsp;If this happens, talk to your doctor or nurse immediately.<\/p>\n\n\n\n<p><em>Laboratory test<\/em><\/p>\n\n\n\n<p>You may show an abnormal result on a laboratory test (so-called Coomb&#8217;s test) which checks for the presence of certain\u00a0antibodies\u00a0that can affect your\u00a0red blood cells.\u00a0If the level of\u00a0red blood cells\u00a0drops, the doctor can check to see if these\u00a0antibodies\u00a0have caused it.<\/p>\n\n\n\n<p>If any of the above applies to you (or if you are not sure), you should consult a doctor or nurse before using Zinforo.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Zinforo<\/h2>\n\n\n\n<p>Tell the doctor or nurse if you are using, have recently used, or might be using other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant, tell your doctor before using Zinforo.&nbsp;Do not use the medicine during pregnancy unless your doctor tells you to.<\/p>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, consult your doctor before using this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Zinforo can cause\u00a0side effects, such as dizziness.\u00a0This may affect your ability to drive and use machines.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Zinforo<\/h2>\n\n\n\n<p>Zinforo is given to you by a doctor or nurse.<\/p>\n\n\n\n<p><em>Dosage<\/em><\/p>\n\n\n\n<p>The usual recommended\u00a0dose\u00a0for adults is 600 mg every 12 hours.\u00a0Your doctor may increase your\u00a0dose\u00a0to 600 mg every 8 hours for certain\u00a0infections.\u00a0The usual recommended\u00a0dose\u00a0for children depends on the child&#8217;s age and weight and is given every 8 or 12 hours.\u00a0It is given as a drip into a vein over 5 to 60 minutes if you receive the usual\u00a0dose\u00a0one or 120 minutes if you receive the increased\u00a0dose\u00a0one.<\/p>\n\n\n\n<p>A treatment usually lasts 5 to 14 days for skin infections and 5 to 7 days for\u00a0pneumonia.<\/p>\n\n\n\n<p><em>Patients with kidney problems<\/em><\/p>\n\n\n\n<p>If you have kidney problems, the doctor may lower the\u00a0dose, as Zinforo is excreted from the body via the kidneys.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use too much Zinforo&nbsp;<\/h2>\n\n\n\n<p>If you think you have been given too much Zinforo, tell the doctor or nurse immediately.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you missed a dose of Zinforo<\/h2>\n\n\n\n<p>If you think you have missed a\u00a0dose, tell the doctor or nurse immediately.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or nurse.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.\u00a0The following\u00a0side effects\u00a0may occur with this medicine:<\/p>\n\n\n\n<p><strong>Tell your doctor immediately if you get these symptoms because you may need&nbsp;emergency&nbsp;medical attention:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sudden swelling of the lips, face, throat, or tongue;\u00a0severe skin rash and trouble swallowing or breathing.\u00a0This can be a sign of a severe\u00a0allergic reaction\u00a0(\u00a0anaphylaxis\u00a0) which can be life-threatening<\/li><li>Diarrhea that becomes severe or prolonged, or stools that contain blood or mucus during or after treatment with Zinforo.\u00a0In this situation, you should not take medicines that stop or calm bowel activity.<\/li><\/ul>\n\n\n\n<p><strong>Very common (&nbsp;<\/strong><strong>may affect more than 1 in 10 people&nbsp;<\/strong><strong>)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Changes in a blood test called the Coombs test, which is commonly seen in patients receiving this type of antibiotic.\u00a0This test checks for the presence of certain\u00a0antibodies\u00a0that can affect your\u00a0red blood cells.<\/li><\/ul>\n\n\n\n<p><strong>Common (&nbsp;<\/strong><strong>may affect up to 1 in 10 people&nbsp;<\/strong><strong>)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fever<\/li><li>Headache<\/li><li>Dizziness<\/li><li>Itching, skin rash<\/li><li>Diarrhea, abdominal pain<\/li><li>Nausea and vomiting<\/li><li>More\u00a0enzymes\u00a0are produced by the liver (seen in blood samples)<\/li><li>Pain and irritation in the veins<\/li><li>Redness, pain, or swelling at the injection site<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (&nbsp;<\/strong><strong>may affect up to 1 in 100 people&nbsp;<\/strong><strong>)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Blood deficiency\u00a0(\u00a0anemia\u00a0)<\/li><li>Raised, itchy rash (\u00a0hives\u00a0)<\/li><li>An increase in the\u00a0creatinine\u00a0level in the blood.\u00a0Creatinine\u00a0shows how well your kidneys are working.<\/li><li>More bleeding or bruising than usual.\u00a0This may be because the level of\u00a0platelets\u00a0in the blood has dropped.<\/li><li>Changes in tests show how well your blood clots.<\/li><li>Decreased total number of\u00a0white blood cells\u00a0or certain\u00a0white blood cells\u00a0in the blood (\u00a0leukopenia\u00a0and\u00a0neutropenia\u00a0)<\/li><li>Changes related to your mental state, e.g.\u00a0confusion, reduced level of consciousness, abnormal movements, or seizures (\u00a0encephalopathy\u00a0) \u2013 these have occurred in people when the\u00a0dose\u00a0they have received is too high, especially people with kidney problems.<\/li><\/ul>\n\n\n\n<p><strong>Rare (&nbsp;<\/strong><strong>may affect up to 1 in 1,000 people&nbsp;<\/strong><strong>)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>A significant decrease in the number of certain\u00a0white blood cells\u00a0in the blood (\u00a0agranulocytosis\u00a0).\u00a0You may have a fever,\u00a0flu-like symptoms, sore throat, or other\u00a0infection\u00a0that can be serious.<\/li><li>An increase in the number of certain\u00a0white blood cells\u00a0in the blood (\u00a0eosinophilia\u00a0).<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurring in an unknown number of users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>A type of lung disease in which the number of&nbsp;eosinophils&nbsp;(a type of&nbsp;white blood cell&nbsp;) increases in the lungs (&nbsp;eosinophilic&nbsp;pneumonia&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Zinforo<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date stated on the packaging.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store at a maximum of 30 \u00b0C.<\/p>\n\n\n\n<p>Store in the original packaging.&nbsp;Light sensitive.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0The hospital disposes of all waste material safely.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Each\u00a0vial\u00a0contains 600 mg of ceftaroline family.<\/li><li>Another ingredient is arginine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Zinforo is a white-yellow to light-yellow powder to concentrate for\u00a0infusion, solution in a\u00a0vial.\u00a0It is available in packs of 10 vials.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Pfizer Ireland Pharmaceuticals<\/p>\n\n\n\n<p>Operations Support Group<\/p>\n\n\n\n<p>Ringaskiddy, County Cork<\/p>\n\n\n\n<p>Ireland<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>ACS Dobfar SpA<\/p>\n\n\n\n<p>Nucleo Industriale S. Atto<\/p>\n\n\n\n<p>64100 Teramo<\/p>\n\n\n\n<p>Italy<\/p>\n\n\n\n<p>ACS Dobfar SpA<\/p>\n\n\n\n<p>Via A. Fleming 2<\/p>\n\n\n\n<p>37135 Verona<\/p>\n\n\n\n<p>Italy<\/p>\n\n\n\n<p>Contact the representative of the Marketing Authorization Holder if you would like to know more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgi\u00eb\/Belgique\/Belgien<\/strong><strong>Luxembourg\/Luxembourg<\/strong>Pfizer NV\/SATel\/Tel: +32 (0)2 554 62 11<\/td><td><b>Lithuania Pfizer<\/b> Luxembourg SARL branches in LithuaniaTel.\u00a0+3705 2514000<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Pfizer Luxembourg \u0421\u0410\u0420\u041b, \u041a\u043b\u043e\u043d \u0411\u0443\u043b\u0433\u0430\u0440\u0438\u044fTel.: +359 2 970 4333<\/td><td><strong>Magyarorsz\u00e1g<\/strong>PFIZER Kft.Tel.&nbsp;+ 36 1 488 37 00<\/td><\/tr><tr><td><strong>Czech Republic Pfizer<\/strong>, coil.\u00a0s iPhone: +420-283-004-111<\/td><td><strong>Malta<\/strong>Vivian Corporation Ltd.Phone: +35621 344610<\/td><\/tr><tr><td><strong>Denmark<\/strong>Pfizer ApSPhone: +45 44 20 11 00<\/td><td><strong>The Netherlands<\/strong>Pfizer by phone: +31 (0)10 406 43 01<\/td><\/tr><tr><td><strong>Deutschland<\/strong>PFIZER PHARMA GmbHPhone: +49 (0)30 550055-51000<\/td><td><strong>Norway<\/strong>Pfizer iPhone: +47 67 52 61 00<\/td><\/tr><tr><td><strong>Estonia<\/strong>Pfizer Luxembourg SARL Eesti branch phone: +372 666 7500<\/td><td><strong>Austria<\/strong>Pfizer Corporation Austria Ges.mbHPhone: +43 (0)1 521 15-0<\/td><\/tr><tr><td><strong>Greece<\/strong>Pfizer \u0395\u039b\u039b\u0391\u03a3 \u0391.\u0395.Tel.: +30 210 67 85 800<\/td><td><strong>Polish<\/strong>Pfizer Polska Sp.&nbsp;z o. oTel.: +48 22 335 61 00<\/td><\/tr><tr><td><strong>Spain<\/strong>Pfizer, SLPhone: +34 91 490 99 00<\/td><td><strong>Portugal<\/strong>Laborat\u00f3rios Pfizer, Lda.Phone: +351 21 423 5500<\/td><\/tr><tr><td><strong>France<\/strong>PfizerTel: +33 (0)1 58 07 34 40<\/td><td><strong>Romania<\/strong>Pfizer Rom\u00e2nia SRLPhone: +40 (0)21 207 28 00<\/td><\/tr><tr><td><strong>Hrvatska<\/strong>Pfizer Croatia dooPhone: + 385 1 3908 777<\/td><td><strong>Slovenija<\/strong>Pfizer Luxembourg SARLPfizer, a branch of marketing, LjubljanaPhone: + 386 (0)1 52 11 400<\/td><\/tr><tr><td><strong>Ireland<\/strong>Pfizer Healthcare IrelandTel: +1800 633 363 (toll-free)+44 (0)1304 616161<\/td><td><strong>Slovenian Republic<\/strong>Pfizer Luxembourg SARL, organiza\u010dn\u00e1 zlo\u017ekaPhone: +421\u20132\u20133355 5500<\/td><\/tr><tr><td><strong>Iceland<\/strong>Icepharma hf.Telephone: +354 540 8000<\/td><td><strong>Finland\/Finland<\/strong>Pfizer OyTel.\/Tel: +358 (0)9 430 040<\/td><\/tr><tr><td><strong>Italy<\/strong>Pfizer SrlPhone: +39 06 33 18 21<\/td><td><strong>Sweden<\/strong>Pfizer ABPhone: +46 (0)8 550 520 00<\/td><\/tr><tr><td><strong>Cyprus<\/strong>Pfizer \u0395\u039b\u039b\u0391\u03a3 \u0391.\u0395.&nbsp;(CYPRUS BRANCH)Phone: +357 22 817690<\/td><td><strong>United Kingdom (Northern Ireland)<\/strong>Pfizer LimitedPhone: +44 (0) 1304 616161<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Zinforo is an antibiotic medicine containing the active substance ceftarolinefosamil.\u00a0It belongs to a group of medicines called &#8220;cephalosporin antibiotics&#8221;.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22506],"tags":[28363,28368,28359,28362,28369,28361,28360,28364,28366,28365,28367],"class_list":["post-35116","post","type-post","status-publish","format-standard","hentry","category-medicines","category-z","tag-benefits-of-ceftaroline-fosamilum","tag-benefits-of-zinforo","tag-ceftaroline-fosamilum","tag-ceftaroline-fosamilum-side-effects","tag-ceftarolinum-fosamilum","tag-what-ceftaroline-fosamilum-is-used-for","tag-what-is-ceftaroline-fosamilum","tag-what-is-zinforo","tag-what-zinforo-is-used-for","tag-zinforo","tag-zinforo-side-effects"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/35116","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=35116"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/35116\/revisions"}],"predecessor-version":[{"id":35401,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/35116\/revisions\/35401"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=35116"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=35116"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=35116"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}