{"id":34557,"date":"2022-11-21T09:39:37","date_gmt":"2022-11-21T09:39:37","guid":{"rendered":"https:\/\/zeepedia.com\/?p=34557"},"modified":"2022-11-22T07:17:42","modified_gmt":"2022-11-22T07:17:42","slug":"zeposia","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/zeposia\/","title":{"rendered":"Zeposia &#8211; Ozanimod uses, dose and side effects"},"content":{"rendered":"\n<p>0.23 mg, 0.46 mg, 0.92 mg&nbsp;hard capsules<br>ozanimod<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Zeposia is and what it is used for<\/h2>\n\n\n\n<p>Zeposia contains the active substance ozanimod, which belongs to a group of medicines that can reduce the number of&nbsp;white blood cells&nbsp;(&nbsp;lymphocytes&nbsp;) that circulate freely in the body.<\/p>\n\n\n\n<p>Zeposia is used for the following diseases:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Multiple sclerosis<\/li><li>Ulcerative colitis<\/li><\/ul>\n\n\n\n<p>Multiple sclerosis<\/p>\n\n\n\n<p>Zeposia is indicated for the treatment of adult patients with relapsing-remitting&nbsp;multiple sclerosis&nbsp;(RRMS) who have active disease.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Multiple sclerosis\u00a0(MS) is a disease in which the immune system (the body&#8217;s defenses, including\u00a0white blood cells\u00a0) mistakenly attacks the protective sheath that surrounds the nerves in the brain and spinal cord.\u00a0This prevents the nerves from working properly and can lead to symptoms such as numbness, difficulty walking, and problems with vision and balance.<\/li><li>In relapsing\u00a0multiple sclerosis, the attacks on the nerve cells are followed by periods of recovery.\u00a0When the\u00a0relapse\u00a0is over, the symptoms may disappear completely, but some problems may also remain.<\/li><\/ul>\n\n\n\n<p>Zeposia helps to protect the nerves against attack by the immune system by preventing certain&nbsp;white blood cells&nbsp;from reaching the brain and spinal cord, where they can cause&nbsp;inflammation&nbsp;and damage the protective covering of the nerves.<\/p>\n\n\n\n<p>Ulcerative colitis<\/p>\n\n\n\n<p>Zeposia is used to treat adult patients with moderately to severely active\u00a0ulcerative colitis.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Ulcerative colitis\u00a0is an\u00a0inflammatory\u00a0disease of the intestine.\u00a0If you have\u00a0ulcerative colitis, you will first be given other medicines.\u00a0If you do not respond well enough or cannot tolerate these medicines, you may be given Zeposia to reduce the signs and symptoms of your disease.<\/li><\/ul>\n\n\n\n<p>Zeposia helps to reduce&nbsp;inflammation&nbsp;in&nbsp;ulcerative colitis&nbsp;by preventing certain&nbsp;white blood cells&nbsp;from reaching the intestine.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Zeposia<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Zeposia:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to ozanimod or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have been told that you have a severely weakened immune system<\/li><li>if you have had a heart attack, angina pectoris,\u00a0stroke\u00a0or mini-stroke (\u00a0transient\u00a0ischemic attack,\u00a0TIA\u00a0), or certain types of severe\u00a0heart failure\u00a0in the last 6 months<\/li><li>if you have certain types of irregular or abnormal heart rhythm (\u00a0arrhythmia\u00a0) &#8211; your doctor will check your heart before starting treatment<\/li><li>if you have a severe\u00a0infection, e.g.\u00a0hepatitis or\u00a0tuberculosis<\/li><li>if you have cancer<\/li><li>if you have severe liver problems<\/li><li>if you are pregnant or may become pregnant (are\u00a0fertile\u00a0) and are not using an effective contraceptive method.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Zeposia:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have a slow heart rate or if you are taking or have recently taken medicines that lower your heart rate (eg\u00a0beta blockers\u00a0or calcium channel blockers)<\/li><li>if you have untreated severe breathing problems during sleep (severe\u00a0sleep apnea\u00a0)<\/li><li>if you have liver problems<\/li><li>if you have an\u00a0infection<\/li><li>if you\u00a0have low levels of a type of\u00a0white blood cell\u00a0called\u00a0lymphocytes<\/li><li>if you have never had, or are not sure if you have had, chickenpox<\/li><li>if you have recently been vaccinated or plan to be vaccinated<\/li><li>if you or others notice worsening of your MS symptoms and any new or unfamiliar symptoms.\u00a0This may be due to a rare\u00a0infection\u00a0of the brain called\u00a0progressive\u00a0multifocal\u00a0leukoencephalopathy (PML).<\/li><li>if you have ever had visual disturbances or other signs of fluid accumulation in the central part of the retina, the\u00a0macula\u00a0(a condition called macular edema)<\/li><li>if you have an\u00a0inflammation\u00a0of the eye (\u00a0uveitis\u00a0)<\/li><li>if you have\u00a0diabetes\u00a0(which can cause eye problems)<\/li><li>if you have a severe lung disease (\u00a0pulmonary fibrosis\u00a0or chronic\u00a0obstructive pulmonary disease, COPD).<\/li><\/ul>\n\n\n\n<p>Before you start taking Zeposia, the doctor will check your heart with an\u00a0EKG\u00a0(\u00a0electrocardiogram\u00a0).\u00a0If you have certain heart conditions, your doctor will monitor you for at least 6 hours after the first\u00a0dose.<\/p>\n\n\n\n<p>As Zeposia can raise&nbsp;blood pressure&nbsp;et, your doctor may want to check your&nbsp;blood pressure&nbsp;regularly.<\/p>\n\n\n\n<p>While you are taking Zeposia (and up to three months after you stop taking the medicine) you may be more likely to get an\u00a0infection.\u00a0If you already have an\u00a0infection, it can get worse.\u00a0Contact a doctor if you get an\u00a0infection.<\/p>\n\n\n\n<p>If you develop symptoms of visual disturbances, increasing (\u00a0progressive\u00a0) weakness, clumsiness, memory loss, or confusion, or if you have MS and you think your disease is gradually getting worse during treatment with Zeposia, contact your doctor immediately.\u00a0These symptoms may be due to a rare\u00a0infection\u00a0of the brain called\u00a0progressive\u00a0multifocal\u00a0leukoencephalopathy (PML) which can lead to severe disability or death.<\/p>\n\n\n\n<p>If you experience symptoms such as severe headache, confusion, convulsions (seizures), or loss of vision during treatment with Zeposia, contact your doctor immediately.\u00a0These symptoms may be due to a condition called posterior reversible encephalopathy syndrome (PRES).<\/p>\n\n\n\n<p>As Zeposia can increase the risk of skin cancer, you should limit exposure to sunlight and UV light (ultraviolet light) by wearing protective clothing and regularly applying sunscreen (with a high sun protection factor).<\/p>\n\n\n\n<p>Fertile women<\/p>\n\n\n\n<p>Zeposia can harm the unborn baby if used during pregnancy.&nbsp;Before you start treatment with Zeposia, your doctor will explain the risk to you and ask you to take a pregnancy test to make sure you are not pregnant.&nbsp;The doctor will give you a card explaining why you should not get pregnant while taking Zeposia.&nbsp;The card also explains what to do to avoid becoming pregnant while taking Zeposia.&nbsp;You must use an effective method of contraception during treatment and for 3 months after the end of treatment (see section&nbsp;<em>&#8220;Pregnancy and breast-feeding&#8221;<\/em>&nbsp;).<\/p>\n\n\n\n<p>If any of these apply to you, talk to your doctor or pharmacist before taking Zeposia.<\/p>\n\n\n\n<p><strong>Exacerbated MS after stopping treatment with Zeposia<\/strong><\/p>\n\n\n\n<p>Tell your doctor straight away if you think your MS is getting worse after you stop taking Zeposia (see \u201cIf you stop taking Zeposia\u201d in section 3).<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children or adolescents under 18 years of age.&nbsp;This is because the drug has not been studied in this age group.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Zeposia<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0This is because Zeposia can affect how other medicines work.\u00a0Some medicines can also affect how Zeposia works.<\/p>\n\n\n\n<p>In particular, before taking Zeposia, tell your doctor or pharmacist if you are taking or have recently taken any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>medicines that inhibit or alter the immune system (eg ciclosporin)<\/li><li>medicines used to treat MS such as alemtuzumab, beta\u00a0interferon, dimethyl fumarate, glatiramer acetate, mitoxantrone, natalizumab, or teriflunomide<\/li><li>medicines used to treat\u00a0ulcerative colitis\u00a0such as azathioprine and 6-mercaptopurine<\/li><li>gemfibrozil to lower the levels of fats or\u00a0cholesterol\u00a0in the blood<\/li><li>clopidogrel, a medicine used to prevent the blood from clotting (clotting)<\/li><li>rifampicin, an\u00a0antibiotic\u00a0used\u00a0to treat\u00a0tuberculosis\u00a0and other serious\u00a0infections<\/li><li>medicines called\u00a0monoamine oxidase inhibitors\u00a0to treat depression (eg phenelzine) or\u00a0Parkinson&#8217;s disease\u00a0(eg\u00a0selegiline\u00a0)<\/li><li>medicines that lower the heart rate (such as\u00a0beta-blockers\u00a0or calcium channel blockers)<\/li><li>certain types of vaccines.\u00a0Live attenuated vaccines should be avoided during treatment and for 3 months after treatment with Zeposia.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, consult your doctor before using this medicine.<\/p>\n\n\n\n<p>Pregnancy<\/p>\n\n\n\n<p>Do not use Zeposia during pregnancy, if you are planning to have a baby or if you may become pregnant and are not using an effective method of contraception.&nbsp;If Zeposia is used during pregnancy, there is a risk of harm to the unborn child.&nbsp;If you can become pregnant, your doctor will inform you of this risk before you start treatment with Zeposia.&nbsp;You will also be given a pregnancy test to make sure you are not pregnant.&nbsp;You must use an effective method of contraception while taking Zeposia and for at least 3 months after you stop taking it.&nbsp;Consult your doctor about reliable birth control methods.<\/p>\n\n\n\n<p>Your doctor will give you a card explaining why you should not become pregnant while taking Zeposia.<\/p>\n\n\n\n<p>Inform your doctor immediately if you become pregnant during treatment with Zeposia.&nbsp;The doctor will decide to stop treatment (see&nbsp;<em>\u201cIf you stop taking Zeposia\u201d<\/em>&nbsp;in section 3).&nbsp;Special maternity care monitoring will be carried out.<\/p>\n\n\n\n<p>Breast-feeding<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You should not breastfeed while taking Zeposia.\u00a0Zeposia can pass into breast milk and there is a risk of serious\u00a0side effects\u00a0in the baby.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Zeposia has no or negligible effect on the ability to drive and use machines.<\/p>\n\n\n\n<p><strong>Zeposia contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;of sodium&nbsp;per capsule, i.e. it is almost &#8216;sodium-free&#8217;.<a><\/a><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Zeposia<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>How much to take<\/strong><\/p>\n\n\n\n<p>When you start taking Zeposia, you should take a low\u00a0dose\u00a0and gradually increase the\u00a0dose\u00a0to reduce any reduction in heart rate.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You will receive a step-up pack to help you start treatment in this way.\u00a0It contains:<ul><li>4 light gray capsules, containing 0.23 mg ozanimod.\u00a0You take one of these on days 1 to 4 of treatment.<\/li><li>3 light gray and orange colored capsules, containing 0.46 mg ozanimod.\u00a0You take one of these on days 5, 6, and 7.<\/li><\/ul><\/li><li>On day 8 and beyond, when you have finished the step-up pack, you will switch to a regular pack of orange capsules containing the recommended\u00a0dose\u00a0one of 0.92 mg ozanimod.\u00a0You will continue regular treatment with one capsule of 0.92 mg daily.<\/li><\/ul>\n\n\n\n<p><strong>How to take&nbsp;<\/strong><strong>Zeposia<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Zeposia is intended for&nbsp;oral&nbsp;use (taken by mouth).<\/li><li>Swallow the capsules whole.<\/li><li>You can take them with or without food.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Zeposia<\/h2>\n\n\n\n<p>If you have taken too much Zeposia, contact a doctor or go to the hospital immediately.\u00a0Take the medicine package and this leaflet with you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Zeposia<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have forgotten a\u00a0dose, take it as soon as you remember.\u00a0If you forget to take a\u00a0dose\u00a0throughout the day, skip the missed\u00a0dose\u00a0and take the next\u00a0dose\u00a0as usual at the time you would normally have taken it.<\/li><li>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/li><li>If you miss one or more\u00a0doses\u00a0during the first 14 days after starting treatment with Zeposia, talk to your doctor about how to resume treatment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Zeposia<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Do not stop taking Zeposia without first talking to your doctor.<\/li><li>Talk to your doctor about how to resume treatment, if you have stopped taking Zeposia:<ul><li>for 1 day or more during the first 14 days of treatment<\/li><li>for more than seven consecutive days between day 15 and day 28 of treatment<\/li><li>for more than 14 consecutive days after day 28 of treatment.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>You will need to start with the &#8220;step-up pack&#8221; again.<\/p>\n\n\n\n<p>Zeposia will remain in your body for up to 3 months after you stop taking the medicine.&nbsp;The number of&nbsp;white blood cells&nbsp;(&nbsp;lymphocyte count&nbsp;) may also remain low during this time and the&nbsp;side effects&nbsp;described in this leaflet may still occur (see&nbsp;<em>\u201cPossible side effects\u201d<\/em>&nbsp;in section 4).<\/p>\n\n\n\n<p>Tell your doctor straight away if you think your MS is getting worse after you stop taking Zeposia.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Serious&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>Contact your doctor or pharmacist immediately if you experience any of the following side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Common:<\/strong>\u00a0may affect up to 1 in 10 users<ul><li>slow heart rate<\/li><li>urinary tract infection<\/li><li>elevated\u00a0blood pressure<\/li><\/ul><\/li><li><strong>Uncommon:<\/strong>\u00a0may affect up to 1 in 100 users<ul><li>allergic reaction \u2013 signs of this can e.g.\u00a0skin rash.<\/li><\/ul><\/li><li><strong>Rare:<\/strong>\u00a0may affect up to 1 in 1,000 users<ul><li>infection\u00a0of the brain called\u00a0progressive\u00a0multifocal\u00a0leukoencephalopathy (PML) (see section 2).<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>Other\u00a0side effects\u00a0ar<\/strong><\/p>\n\n\n\n<p>Talk to your doctor or pharmacist if you notice any of the following side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Very common:<\/strong>\u00a0may affect more than 1 in 10 users<ul><li>infection\u00a0in the nose or nostrils, nasal cavity, mouth, throat (\u00a0pharynx\u00a0), or larynx (\u00a0larynx\u00a0) caused by\u00a0viruses<\/li><li>low levels of a type of\u00a0white blood\u00a0cell\u00a0called\u00a0lymphocytes<\/li><\/ul><\/li><li>Common:\u00a0may affect up to 1 in 10 users<ul><li>inflammation\u00a0of the throat (\u00a0pharyngitis\u00a0)<\/li><li>respiratory infection (signs of\u00a0infection\u00a0in the lungs)<\/li><li>herpes\u00a0zoster (\u00a0shingles\u00a0)<\/li><li>herpes\u00a0simplex or cold sores (oral herpes)<\/li><li>headache<\/li><li>blood pressure drop<\/li><li>swelling, especially of the ankles and feet, due to fluid retention (peripheral\u00a0edema)<\/li><li>increased liver enzyme levels in blood tests (a sign of liver problems) or yellow\u00a0pigmentation\u00a0of the skin,\u00a0mucous membranes,\u00a0or eyes (jaundice)<\/li><li>affected lung function which can lead to shortness of breath<\/li><\/ul><\/li><li><strong>Uncommon:<\/strong>\u00a0may affect up to 1 in 100 users<ul><li>blurred vision (macular edema)<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Zeposia<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Use before the expiry date which is stated on the blister and carton after &#8220;EXP&#8221;.\u00a0The expiration date is the last day of the specified month.<\/li><li>Store at a maximum of 25 \u00b0C.<\/li><li>Do not use this medicine if the packaging is damaged or appears to have been tampered with.<\/li><li>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is ozanimod.<ul><li><em>Zeposia 0.23 mg hard capsules<\/em><\/li><li>Each hard capsule contains 0.23 mg ozanimod (as hydrochloride).<\/li><li><em>Zeposia 0.46 mg hard capsules<\/em><\/li><li>Each hard capsule contains 0.46 mg ozanimod (as hydrochloride).<\/li><li><em>Zeposia 0.92 mg hard capsules<\/em><\/li><li>Each hard capsule contains 0.92 mg ozanimod (as hydrochloride).<\/li><\/ul><\/li><li>Other ingredients are<ul><li><em>Capsule contents:<\/em><\/li><li>Microcrystalline cellulose,\u00a0colloidal\u00a0anhydrous silica, croscarmellose sodium, and magnesium stearate.<\/li><li>Capsule shell:<ul><li>Each 0.23 mg capsule contains gelatin, titanium dioxide (E171), yellow iron oxide (E172), black iron oxide (E172), and red iron oxide (E172).<\/li><li>Each 0.46 mg capsule contains gelatin, titanium dioxide (E171), yellow iron oxide (E172), black iron oxide (E172), and red iron oxide (E172).<\/li><li>Each 0.92 mg capsule contains gelatin, titanium dioxide (E171), iron oxide yellow (E172), and iron oxide red (E172).<\/li><\/ul><\/li><li><em>Marking ink:<\/em>\u00a0black iron oxide (E172), shellac (E904), propylene glycol (E1520), concentrated ammonia solution (E527) and potassium hydroxide (E525)<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Zeposia 0.23 mg hard capsule, 14.3 mm long, has a light gray,\u00a0opaque\u00a0(opaque) cap and cap, marked with \u201cOZA\u201d on the cap and \u201c0.23 mg\u201d on the cap in black ink.<\/li><li>Zeposia 0.46 mg hard capsule, 14.3 mm long, has an orange,\u00a0opaque\u00a0cap, and light gray cap, marked with \u201cOZA\u201d on the cap and \u201c0.46 mg\u201d on the cap in black ink.<\/li><li>Zeposia 0.92 mg hard capsule, 14.3 mm long, has an orange, opaque cap and body, marked with \u201cOZA\u201d on the cap and \u201c0.92 mg\u201d on the cap in black ink.<\/li><\/ul>\n\n\n\n<p>Package sizes<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>&#8220;Step-up pack&#8221; is a wallet pack containing 7 hard capsules: 4 x 0.23 mg hard capsules and 3 x 0.46 mg hard capsules.<\/li><li>Packages containing 28 x 0.92 mg hard capsules or 98 x 0.92 mg hard capsules.<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Bristol-Myers Squibb Pharma EEIG<\/p>\n\n\n\n<p>Plaza 254<\/p>\n\n\n\n<p>Blanchardstown Corporate Park 2<\/p>\n\n\n\n<p>Dublin 15, D15 T867<\/p>\n\n\n\n<p>Ireland<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Celgene Distribution BV<\/p>\n\n\n\n<p>Orteliuslaan 1000<\/p>\n\n\n\n<p>3528 BD Utrecht<\/p>\n\n\n\n<p>Netherlands<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zeposia contains the active substance ozanimod, which belongs to a group of medicines that can reduce the number of\u00a0white blood cells\u00a0(\u00a0lymphocytes\u00a0) that circulate freely in the body.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22506],"tags":[28301,28304,28295,28300,28296,28298,28297,28302,28299,28303],"class_list":["post-34557","post","type-post","status-publish","format-standard","hentry","category-medicines","category-z","tag-benefits-of-ozanimod","tag-benefits-of-zeposia","tag-ozanimod","tag-ozanimod-side-effects","tag-what-is-ozanimod","tag-what-is-zeposia","tag-what-ozanimod-is-used-for","tag-what-zeposia-is-used-for","tag-zeposia","tag-zeposia-side-effects"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/34557","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=34557"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/34557\/revisions"}],"predecessor-version":[{"id":35066,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/34557\/revisions\/35066"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=34557"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=34557"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=34557"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}