{"id":31567,"date":"2022-11-11T10:35:00","date_gmt":"2022-11-11T10:35:00","guid":{"rendered":"https:\/\/zeepedia.com\/?p=31567"},"modified":"2022-11-12T10:11:54","modified_gmt":"2022-11-12T10:11:54","slug":"wilzin","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/wilzin\/","title":{"rendered":"Wilzin &#8211; Zinc uses, dose and side effects"},"content":{"rendered":"\n<p>25 mg and 50 mg&nbsp;hard capsule<br>zinc<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">WHAT WILZIN IS AND WHAT IT IS USED FOR<\/h2>\n\n\n\n<p>Wilzin belongs to the drug group Other agents for digestion and metabolism.<\/p>\n\n\n\n<p>Wilzin is indicated for the treatment of Wilson&#8217;s disease, which is a rare inherited&nbsp;defect&nbsp;in copper excretion.&nbsp;Copper from food, which cannot be eliminated properly, accumulates first in the liver and then in other organs such as the eyes and brain.&nbsp;This can potentially lead to liver damage and neurological disorders.<\/p>\n\n\n\n<p>Wilzin blocks the\u00a0absorption\u00a0of copper from the intestine and thereby prevents copper from being transferred to the blood and further accumulating in the body.\u00a0The copper that has not been absorbed is excreted via the feces.<\/p>\n\n\n\n<p>Wilson&#8217;s disease persists throughout life and therefore the need for this treatment is lifelong.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">BEFORE YOU TAKE WILZIN<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Wilzin:<\/h2>\n\n\n\n<p>If you are allergic (hypersensitive) to zinc or any of the other ingredients in Wilzin.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Be especially careful with Wilzin<\/h2>\n\n\n\n<p>Wilzin is not usually recommended as initial therapy in patients with signs and symptoms of Wilson&#8217;s disease because of its slow onset of action.<\/p>\n\n\n\n<p>If you are being treated with another anti-copper medicine, such as penicillamine, your doctor may add Wilzin before the first treatment is finished.<\/p>\n\n\n\n<p>As with other anti-copper medicines, such as penicillamine, your symptoms may get worse after treatment is started.&nbsp;If this is the case, you must inform your doctor.<\/p>\n\n\n\n<p>To monitor your condition and your treatment, your doctor will regularly check your blood and urine.\u00a0This ensures that you receive adequate treatment.\u00a0Monitoring can detect insufficient treatment (copper excess) or excess treatment (copper deficiency), both of which can be harmful, especially for growing children and pregnant women.<\/p>\n\n\n\n<p>You should talk to your doctor if you experience unusual muscle weakness or abnormal sensations in your arms and legs as this may indicate overtreatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Intake of other medicines:<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including those obtained without a prescription.<\/p>\n\n\n\n<p>Consult your doctor before taking any other medicines that can reduce the effect of Wilzin such as iron, calcium supplements,\u00a0tetracyclines\u00a0(\u00a0antibiotics\u00a0), or phosphorus.\u00a0Conversely, the effect of certain drugs, such as iron,\u00a0tetracyclines,\u00a0or\u00a0fluoroquinolones\u00a0(\u00a0antibiotics\u00a0), can be reduced by Wilzin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Taking Wilzin with food and drink<\/h2>\n\n\n\n<p>Wilzin should be taken on an empty stomach between meals.\u00a0Especially fiber and some milk products can delay\u00a0the absorption\u00a0of zinc salts.\u00a0Some patients experience stomach discomfort after the morning dose.\u00a0If you experience this, discuss it with your doctor.<\/p>\n\n\n\n<p>This side effect can be reduced if the morning dose is postponed until mid-morning (between breakfast and lunch) or if the first\u00a0dose\u00a0of Wilzin is taken together with a small amount of food containing\u00a0protein, such as meat (but not milk).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy<\/h2>\n\n\n\n<p>Consult your doctor if you plan to become pregnant.&nbsp;It is very important to continue the anti-copper treatment throughout the pregnancy.<\/p>\n\n\n\n<p>If you become pregnant during treatment with Wilzin, your doctor will decide which treatment and which\u00a0dose\u00a0is best for your situation.<\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p>Breastfeeding should be avoided if you are treated with Wilzin.\u00a0Discuss this with your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>No studies have been done regarding the impact on the ability to drive and use machines.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Important information about some of the excipients in Wilzin:<\/h2>\n\n\n\n<p>Wilzin 50 mg hard capsules contain para-orange (E110) which can cause allergic reactions.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">HOW TO TAKE WILZIN<\/h2>\n\n\n\n<p>Always take Wilzin as directed by your doctor.\u00a0Ask your doctor or pharmacist if you are unsure.\u00a0For the different dosage regimens, Wilzin is available in 25 mg or 50 mg hard capsules.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><em>Adults<\/em>&nbsp;:<br>The usual&nbsp;dose&nbsp;is one hard capsule of Wilzin 50 mg (or two hard capsules of Wilzin 25 mg) three times daily.&nbsp;The maximum daily dose is one hard capsule of Wilzin 50 mg (or two hard capsules of Wilzin 25 mg) 5 times a day.<\/li><li><em>Children and adolescents<\/em>&nbsp;:<br>The usual&nbsp;doses&nbsp;are:<ul><li>from 1 to 6 years: 1 hard capsule of Wilzin 25 mg twice daily<\/li><li>from 6 to 16 years if the body weight is under 57 kg: 1 hard capsule of Wilzin 25 mg three times daily<\/li><li>from 16 years or if the body weight is over 57 kg: 2 hard capsules of Wilzin 25 mg or 1 hard capsule of Wilzin 50 mg three times daily.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>Always take Wilzin on an empty stomach, at least one hour before or 2-3 hours after meals.\u00a0If the morning dose is not well tolerated (see section 4), it is possible to postpone it until mid-morning, between breakfast and lunch.\u00a0It is also possible to take Wilzin with some\u00a0protein, such as meat.<\/p>\n\n\n\n<p>If you have been prescribed Wilzin with another anti-copper medicine, such as&nbsp;penicillamine, allow at least one hour between the two medications.<\/p>\n\n\n\n<p>If you give Wilzin to children who cannot swallow the capsules, open the capsule and mix the powder with a little water (possibly water flavored with sugar or&nbsp;syrup&nbsp;).<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take too much Wilzin:<\/h2>\n\n\n\n<p>If you take more Wilzin than prescribed, you may experience nausea, vomiting, and dizziness.\u00a0If this is the case, you must consult your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Wilzin:<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a\u00a0missed dose.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">POSSIBLE SIDE EFFECTS<\/h2>\n\n\n\n<p>Like all medicines, Wilzin can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>These&nbsp;side effects&nbsp;may occur according to specific frequencies, which are defined as follows:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>very common: affects more than 1 in 10 users<\/li><li>common: affects 1 to 10 in 100 users<\/li><li>less common: affects 1 to 10 users in 1,000<\/li><li>rare: affects 1 to 10 in 10,000 users<\/li><li>very rare: affects less than 1 in 10,000 users<\/li><li>frequency not known: cannot be estimated from available data<\/li><\/ul>\n\n\n\n<p><em>Usual:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>After taking Wilzin, stomach irritation may occur, especially at the beginning of treatment.<\/li><li>Changes in blood tests have been reported including an increase in certain liver and pancreatic enzymes.<\/li><\/ul>\n\n\n\n<p><em>Less common:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>A decrease in red and&nbsp;white blood cells&nbsp;may occur.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">HOW TO STORE WILZIN<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Store out of sight and reach of children.<br><\/li><li>Use before the expiry date which is stated on the can and carton, after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/li><li>Store at a maximum of 25\u00baC.<\/li><\/ul>\n\n\n\n<p>The medicine must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to deal with medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">OTHER INFORMATION<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is zinc.\u00a0Each hard capsule contains 25 mg zinc (equivalent to 83.92 mg zinc acetate dihydrate) or 50 mg zinc (equivalent to 167.84 mg zinc acetate dihydrate).<\/li><li>Other ingredients are cornstarch and magnesium stearate.\u00a0The capsule shell contains gelatin, titanium dioxide (E171), and\u00a0antigen\u00a0brilliant blue FCF (E133) for Wilzin 25 mg, or para-orange (E110) for Wilzin 50 mg.\u00a0The printing ink contains black iron oxide (E172) and shellac.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Wilzin 25 mg is a water blue hard capsule, marked &#8220;93-376&#8221;.<\/p>\n\n\n\n<p>Wilzin 50 mg is an orange opaque hard capsule, marked &#8220;93-377&#8221;.<\/p>\n\n\n\n<p>Available in packs of 250 hard capsules in polyethylene cans with polypropylene and polyethylene closures.&nbsp;The jars also contain a cotton filling.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Recordati Rare Diseases<\/p>\n\n\n\n<p>Building &#8220;Le Wilson&#8221;<\/p>\n\n\n\n<p>70, avenue du G\u00e9n\u00e9ral de Gaulle<\/p>\n\n\n\n<p>F-92800 Puteaux<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Recordati Rare Diseases<\/p>\n\n\n\n<p>Building &#8220;Le Wilson&#8221;<\/p>\n\n\n\n<p>70, avenue du G\u00e9n\u00e9ral de Gaulle<\/p>\n\n\n\n<p>F-92800 Puteaux<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Recordati Rare Diseases<\/p>\n\n\n\n<p>Eco River Park<\/p>\n\n\n\n<p>30, rue des Peupliers<\/p>\n\n\n\n<p>F-92000 Nanterre<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p>For further information about this medicine, contact the representative of the marketing authorization holder.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgique\/Belgi\u00eb\/Belgien<\/strong>RecordatiT\u00e9l\/Tel: +32 2 46101 36<\/td><td><strong>Lithuania<\/strong>Recordati AB.Phone: + 46 8 545 80 230Sweden<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Recordati Rare DiseasesTel.: +33 (0)1 47 73 64 58France<\/td><td><strong>Luxembourg\/Luxembourg<\/strong>RecordatiT\u00e9l\/Tel: +32 2 46101 36Belgique\/Belgium<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Recordati Rare DiseasesPhone: +33 (0)1 47 73 64 58Francie<\/td><td><strong>Magyarorsz\u00e1g<\/strong>Recordati Rare DiseasesPhone: +33 (0)1 47 73 64 58France<\/td><\/tr><tr><td><strong>Denmark<\/strong>Recordati AB.Phone: +46 8 545 80 230Sweden<\/td><td><strong>Malta<\/strong>Recordati Rare DiseasesPhone: +33 1 47 73 64 58Franza<\/td><\/tr><tr><td><strong>Deutschland<\/strong>Recordati Rare Diseases Germany GmbHPhone: +49 731 140 554 0<\/td><td><strong>The Netherlands<\/strong>RecordatiPhone: +32 2 46101 36Belgium<\/td><\/tr><tr><td><strong>Estonia<\/strong>Recordati AB.Phone: + 46 8 545 80 230Roots<\/td><td><strong>Norway<\/strong>Recordati AB.Phone: +46 8 545 80 230Sweden<\/td><\/tr><tr><td><strong>Greece<\/strong>Recordati Rare DiseasesPhone: +33 1 47 73 64 58France<\/td><td><strong>Austria<\/strong>Recordati Rare Diseases Germany GmbHPhone: +49 731 140 554 0Deutschland<\/td><\/tr><tr><td><strong>Spain<\/strong>Recordati Rare Diseases Spain SLUPhone: + 34 91 659 28 90<\/td><td><strong>Polish<\/strong>Recordati Rare DiseasesPhone: +33 (0)1 47 73 64 58France<\/td><\/tr><tr><td><strong>France<\/strong>Recordati Rare DiseasesTel: +33 (0)1 47 73 64 58<\/td><td><strong>Portugal<\/strong>Jaba Recordati SAPhone: +351 21 432 95 00<\/td><\/tr><tr><td><strong>Hrvatska<\/strong>Recordati Rare DiseasesTel: +33 (0)1 47 73 64 58France<\/td><td><strong>Romania<\/strong>Recordati Rare DiseasesPhone: +33 (0)1 47 73 64 58France<\/td><\/tr><tr><td><strong>Ireland<\/strong>Recordati Rare Diseases.Phone: +33 (0)1 47 73 64 58France<\/td><td><strong>Slovenija<\/strong>Recordati Rare DiseasesPhone: +33 (0)1 47 73 64 58France<\/td><\/tr><tr><td><strong>Iceland<\/strong>Recordati AB.Simi: +46 8 545 80 230Sweden<\/td><td><strong>Slovenian Republic<\/strong>Recordati Rare DiseasesPhone: +33 (0)1 47 73 64 58France<\/td><\/tr><tr><td><strong>Italy<\/strong>Recordati Rare Diseases Italy SrlPhone: +39 02 487 87 173<\/td><td><strong>Finland\/Finland<\/strong>Recordati AB.Tel: +46 8 545 80 230Sweden<\/td><\/tr><tr><td><strong>Cyprus<\/strong>Recordati Rare DiseasesPhone: +33 1 47 73 64 58France<\/td><td><strong>Sweden<\/strong>Recordati AB.Phone: +46 8 545 80 230<\/td><\/tr><tr><td><strong>Latvia<\/strong>Recordati AB.Phone: + 46 8 545 80 230Sweden<\/td><td><strong>United Kingdom<\/strong>Recordati Rare Diseases UK Ltd.Phone: +44 (0)1491 414333<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Wilzin belongs to the drug group Other agents for digestion and metabolism.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200],"tags":[27930,27931,27927,24177,27926,27925,27929,27928,19572,27933],"class_list":["post-31567","post","type-post","status-publish","format-standard","hentry","category-medicines","tag-benefits-of-wilzin","tag-side-effects-of-wilzin","tag-what-is-wilzin","tag-what-is-zinc","tag-what-wilzin-is-used-for","tag-wilzin","tag-wilzin-capsule","tag-wilzin-side-effects","tag-zinc","tag-zinc-capsule"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31567","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=31567"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31567\/revisions"}],"predecessor-version":[{"id":32087,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31567\/revisions\/32087"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=31567"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=31567"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=31567"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}