{"id":31524,"date":"2022-11-10T12:17:52","date_gmt":"2022-11-10T12:17:52","guid":{"rendered":"https:\/\/zeepedia.com\/?p=31524"},"modified":"2022-11-11T10:26:24","modified_gmt":"2022-11-11T10:26:24","slug":"waran","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/waran\/","title":{"rendered":"Waran &#8211; Warfarin sodium uses, dose and side effects"},"content":{"rendered":"\n<p>2.5 mg&nbsp;tablets<br>warfarin sodium<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Waran is and what it is used for<\/h2>\n\n\n\n<p>The active substance&nbsp;warfarin&nbsp;inhibits the blood&#8217;s ability to clot (coagulate) and thereby prevents the formation of blood clots in the blood vessels.<\/p>\n\n\n\n<p>Waran is used in case of increased propensity for blood clots.<\/p>\n\n\n\n<p>The warfarin contained\u00a0in Waran may also be approved to treat other conditions not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Waran<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Waran<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to\u00a0warfarin\u00a0or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have a greatly increased tendency to bleed or ongoing bleeding<\/li><li>in case of severe liver disease<\/li><li>if you use herbal remedies containing\u00a0St. John&#8217;s wort\u00a0(\u00a0<em>Hypericum perforatum<\/em>\u00a0)<\/li><li>during the first third and the last four weeks of pregnancy, see Pregnancy and breastfeeding.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p><em>Tell the doctor if you:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>already using, before you start using or stop using other medicines during treatment with Waran (see also Other medicines and Waran)<\/li><li>have diseases of the blood vessels of the brain (cerebrovascular diseases)<\/li><li>have thyroid disorders<\/li><li>has\u00a0heart failure\u00a0with liver damage<\/li><li>have reduced kidney function<\/li><li>have reduced liver function<\/li><li>have uncontrolled high\u00a0blood pressure<\/li><li>previously had bleeding, for example, brain bleeding or bleeding in the gastrointestinal tract<\/li><li>have\u00a0protein\u00a0C deficiency or\u00a0protein\u00a0S deficiency (disorders that can lead to an increased risk of blood clots).<\/li><\/ul>\n\n\n\n<p>Major changes in eating habits should be avoided because the amount of\u00a0vitamin K\u00a0in the food can affect the effectiveness of treatment with Waran.\u00a0Examples of this are switching to an exclusively vegetarian diet or extreme dieting.\u00a0Conditions that affect food absorption, such as diarrhea and vomiting, can also affect the effect of Waran.<\/p>\n\n\n\n<p>Before surgical procedures or tooth extraction, you must inform the doctor or dentist that you are being treated with Waran.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Waran<\/h2>\n\n\n\n<p>Consult a doctor if you use, before you start using, or stop using other medicines, even non-prescription ones, natural medicines such as\u00a0St. John&#8217;s wort\u00a0or other natural products,\u00a0vitamins,\u00a0and dietary supplements, during treatment with Waran.<\/p>\n\n\n\n<p>Medicines containing\u00a0acetylsalicylic acid\u00a0or\u00a0NSAIDs\u00a0(anti-inflammatory\u00a0drugs, e.g.\u00a0ibuprofen,\u00a0naproxen,\u00a0diclofenac\u00a0) give an increased tendency to bleed together with Waran and should not be used as a rule.<\/p>\n\n\n\n<p>For temporary pain conditions, cold symptoms, and fever, only medicines containing\u00a0paracetamol\u00a0should be used.\u00a0Take as low a\u00a0dose\u00a0as possible, because even\u00a0paracetamol\u00a0in high\u00a0doses\u00a0can affect the effect of Waran.\u00a0Regular use of\u00a0paracetamol\u00a0should be avoided.<\/p>\n\n\n\n<p>Glucosamine&nbsp;(against&nbsp;osteoarthritis&nbsp;) can enhance the effect of Waran.<\/p>\n\n\n\n<p>Many other medicines affect the therapeutic effect of Waran, which means that it may be necessary to change the\u00a0dosage\u00a0or take other precautions when Waran is taken at the same time as several other medicines.\u00a0It is therefore essential that treating physicians are aware of all other concomitant medications.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Waran with food and drink<\/h2>\n\n\n\n<p>Cranberries should be avoided during treatment with Waran.<\/p>\n\n\n\n<p>The daily intake of vitamin K-rich foods such as cabbage, broccoli, spinach, and avocado should be as even as possible.\u00a0Changes in the amount of\u00a0vitamin K\u00a0in food can affect Warren&#8217;s effect.<\/p>\n\n\n\n<p>Alcohol can affect the effect of Waran.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em>: Risk of harmful effects to the fetus.\u00a0Therefore, do not use Waran during pregnancy other than on a specific\u00a0prescription\u00a0from a doctor.\u00a0During the first third and the last four weeks of pregnancy, Waran should not be used.<\/p>\n\n\n\n<p><em>Breastfeeding<\/em>: No known risks.<\/p>\n\n\n\n<p><em>Fertility<\/em>: Women of childbearing potential should use effective contraception during treatment with Waran.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>The warranty does not affect the ability to drive or use machines.<\/p>\n\n\n\n<p><strong>The product contains&nbsp;lactose<\/strong><\/p>\n\n\n\n<p>The product contains\u00a0lactose.\u00a0If you have an intolerance to certain sugars, you should consult your doctor before taking this medicine.<\/p>\n\n\n\n<p><strong>Waran is next to &#8220;sodium-free&#8221;<\/strong><\/p>\n\n\n\n<p>Waran contains less than 23 mg of\u00a0sodium\u00a0per\u00a0dose, i.e. is almost &#8220;sodium-free&#8221;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use the Waran<\/h2>\n\n\n\n<p>Always use this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The dose&nbsp;is determined by the doctor who adjusts it individually for you.&nbsp;The full&nbsp;dose&nbsp;should be taken at the same time each day.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you used too much Waran&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<p>If the dose\u00a0of Waran is too high, you may have an increased tendency to bleed, for example, blood in the urine or stool, skin bleeding (bruises), or bleeding in the gums.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forgot to use Waran<\/h2>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a missed tablet.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Talk to your doctor immediately if you experience any of the following side effects:<\/p>\n\n\n\n<p>Painful skin rash.\u00a0In rare cases,\u00a0warfarin\u00a0can cause serious skin conditions, including a condition called calciphylaxis which may start as a painful skin rash but can lead to other serious complications.\u00a0This\u00a0side effect\u00a0is more common in patients with\u00a0chronic\u00a0kidney disease.<\/p>\n\n\n\n<p><em>Very common (&nbsp;<\/em><em>may affect more than 1 in 10 users):<\/em><\/p>\n\n\n\n<p>Bleeding from various organs.&nbsp;Always contact a doctor if you experience bleeding.<\/p>\n\n\n\n<p><em>Common (&nbsp;<\/em><em>may affect up to 1 in 10 users&nbsp;<\/em><em>):<\/em><\/p>\n\n\n\n<p>Increased sensitivity to&nbsp;warfarin&nbsp;during long-term treatment.<\/p>\n\n\n\n<p><em>Uncommon (&nbsp;<\/em><em>may affect up to 1 in 100 users&nbsp;<\/em><em>):<\/em><\/p>\n\n\n\n<p>Anemia, vomiting, nausea, diarrhea.<\/p>\n\n\n\n<p><em>Rare (&nbsp;<\/em><em>may affect up to 1 in 1,000 users):<\/em>&nbsp;<\/p>\n\n\n\n<p>Skin rash,\u00a0hives,\u00a0itching, hair loss, liver damage, jaundice, local vascular inflammation in the skin, tissue damage, tissue damage in the skin.<\/p>\n\n\n\n<p><em>Very rare (&nbsp;<\/em><em>may affect up to 1 in 10,000 users&nbsp;<\/em><em>):<\/em><\/p>\n\n\n\n<p>Hypersensitivity reaction, blue toe syndrome (painful, bluish discoloration of the toes), dark or black stools.<\/p>\n\n\n\n<p><em>No known frequency (&nbsp;<\/em><em>occurs in an unknown number of users&nbsp;<\/em><em>):<\/em><\/p>\n\n\n\n<p>Abdominal pain (due to bleeding), accumulation of\u00a0calcium\u00a0in the blood vessel wall (which leads to enlarging and painful sores on the skin).\u00a0Impaired kidney function in severe anticoagulation and the presence of blood in the urine (anticoagulation-related nephropathy\u00a0).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How the Warrant is to be stored<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date stated on the label after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is warfarin sodium 2.5 mg per tablet.<\/li><li>Other ingredients are\u00a0lactose monohydrate\u00a050 mg per tablet, corn starch, calcium hydrogen phosphate dihydrate, povidone, magnesium stearate, and indigo carmine (dye E 132).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>The tablets are blue and round with a gross score.<\/p>\n\n\n\n<p>The tablet can be divided into two equal\u00a0doses\u00a0(but not into four equal\u00a0doses\u00a0).<\/p>\n\n\n\n<p><em>Package sizes:<\/em><\/p>\n\n\n\n<p>100 tablets in a plastic jar<\/p>\n\n\n\n<p>98 x 1 tablet in the single-dose blister<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Orifarm Healthcare A\/S<\/p>\n\n\n\n<p>Energizer 15<\/p>\n\n\n\n<p>5260 Odense S<\/p>\n\n\n\n<p>Denmark<\/p>\n\n\n\n<p>info@orifarm.com<\/p>\n\n\n\n<p><strong>Local Representative<\/strong><\/p>\n\n\n\n<p>Orifarm Healthcare Box 56048 102 17 Stockholm<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Orifarm Manufacturing Poland Sp.&nbsp;z o. o<\/p>\n\n\n\n<p>Ul.&nbsp;Ksi\u0119stwa \u0141owickiego 12<\/p>\n\n\n\n<p>99-420 \u0141yszkowice<\/p>\n\n\n\n<p>Poland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The active substance\u00a0warfarin\u00a0inhibits the blood&#8217;s ability to clot (coagulate) and thereby prevents the formation of blood clots in the blood vessels.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22503],"tags":[27842,27845,27834,27832,27833,27843,27835,27844,27836],"class_list":["post-31524","post","type-post","status-publish","format-standard","hentry","category-medicines","category-w","tag-waran","tag-waran-tablet","tag-warfarin-sodium","tag-warfarin-sodium-side-effects","tag-warfarin-sodium-tablet","tag-what-is-waran","tag-what-is-warfarin-sodium","tag-what-waran-is-used-forwaran-side-effects","tag-what-warfarin-sodium-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31524","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=31524"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31524\/revisions"}],"predecessor-version":[{"id":31560,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31524\/revisions\/31560"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=31524"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=31524"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=31524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}