{"id":31406,"date":"2022-11-09T07:27:01","date_gmt":"2022-11-09T07:27:01","guid":{"rendered":"https:\/\/zeepedia.com\/?p=31406"},"modified":"2023-02-09T11:12:57","modified_gmt":"2023-02-09T11:12:57","slug":"vydura","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/vydura\/","title":{"rendered":"Vydura &#8211; Rimegepant Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Vydura 75 mg&nbsp;Freeze Dried Rimegepant Tablet<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Vydura Is And What It Is Used For<\/h2>\n\n\n\n<p>Vydura contains the active substance rimegepant, which prevents the activity of a substance in the body called calcitonin gene-related&nbsp;peptide&nbsp;(CGRP).&nbsp;People with&nbsp;migraines&nbsp;may have elevated levels of CGRP.<\/p>\n\n\n\n<p>Vydura rimegepant binds to the receptor for CGRP, thereby reducing the ability of CGRP to also bind to the receptor.&nbsp;This reduces CGRP activity and has two effects:<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>It can interrupt an ongoing <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/migraine\/\">migraine<\/a> attack.<\/li><li>It can reduce the number of migraine attacks if taken preventively.<\/li><\/ol>\n\n\n\n<p>Vydura is used to treat and prevent migraine attacks in adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What You Need To Know Before You Take Vydura<\/h2>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Do Not Take Vydura<\/span><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to vydura rimegepant or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Vydura if any of the following apply to you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You have severe liver problems.<\/li><li>Your kidney function is impaired, or you are on&nbsp;dialysis.<\/li><\/ul>\n\n\n\n<p>When you are treated with Vydura, you must stop taking this medicine and inform the doctor immediately.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you get symptoms of an&nbsp;allergic reaction, e.g.&nbsp;breathing problems or severe skin rash.&nbsp;These symptoms may appear several days after you take medicine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People<\/h2>\n\n\n\n<p>Vydura should not be given to children and adolescents under 18 years of age as it has not been studied in this age group.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Vydura<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;The reason is that some medicines can affect how Vydura works, and Vydura can affect how other medicines work.<\/p>\n\n\n\n<p>The following are examples of drugs to avoid when being treated with Vydura:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Itraconazole and clarithromycin (used against fungal or bacterial infections)<\/li><li>Ritonavir and efavirenz (used&nbsp;against&nbsp;HIV&nbsp;infection&nbsp;)<\/li><li>Bosentan&nbsp;(used for high&nbsp;blood pressure&nbsp;)<\/li><li>St. John&#8217;s wort&nbsp;((traditional) herbal remedy for mild <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/depression\/\">depression<\/a> and mild <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/anxiety-strong-feelings-of-worry\/\">anxiety<\/a>)<\/li><li>Phenobarbital (used for&nbsp;epilepsy&nbsp;)<\/li><li>Rifampicin (used for&nbsp;tuberculosis&nbsp;)<\/li><li>Modafinil (used for&nbsp;narcolepsy&nbsp;).<\/li><\/ul>\n\n\n\n<p>Do not take Vydura more often than once every other day (every 48 hours) if you also take<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fluconazole\u00a0or erythromycin (used against fungal or bacterial infections)<\/li><li>Diltiazem,\u00a0quinidine,\u00a0or verapamil (used for abnormal heart rhythm, chest <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a> (<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/heart-blood-and-lymph-nodes\/angina\/\">angina<\/a>), or high\u00a0blood pressure\u00a0)<\/li><li>Ciclosporin (used to prevent organ rejection after transplantation).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding, And Fertility<\/h2>\n\n\n\n<p>If you are pregnant, think you may be pregnant, or plan to have a baby, ask your doctor or pharmacist for advice before using this medicine. The use of Vydura during pregnancy should be avoided as the effects of the medicine on pregnant women are unknown.<\/p>\n\n\n\n<p>If you are breastfeeding or plan to breastfeed, consult your doctor or pharmacist before using this medicine.&nbsp;You and your doctor should decide if you should use Vydura while breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving Ability And Use Of Machinery<\/h2>\n\n\n\n<p>Vydura Pfizer is not expected to affect your ability to drive or use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How To Use Vydura<\/h2>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Vydura uses:<\/span><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Always take this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/li><li><strong>How much to take<\/strong><ul><li>To prevent&nbsp;migraines, the recommended&nbsp;dose&nbsp;is one freeze-dried tablet (75 mg rimegepant) every other day.<\/li><li>For the treatment of a migraine attack that has already started, the recommended&nbsp;dose&nbsp;is one freeze-dried tablet (75 mg rimegepant) as needed, but not more than once daily.<\/li><li>The highest daily&nbsp;dose&nbsp;is one freeze-dried tablet (75 mg rimegepant) per day.<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>How To Take This Medicine<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Vydura is intended for&nbsp;oral&nbsp;use.<\/li><li>The freeze-dried tablet can be taken with or without food or water.<\/li><li>Instructions:<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20210212000017#\" rel=\"noopener\"><\/a><\/td><td>Your hands must be dry when you open the package.&nbsp;Peel off the foil from a blister and carefully pick up the freeze-dried tablet.&nbsp;The tablet should&nbsp;<strong>not<\/strong>&nbsp;be pushed out through the foil.<\/td><\/tr><tr><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20210212000017#\" rel=\"noopener\"><\/a><\/td><td>Immediately place the tablet under or on top of the tongue, where it dissolves.&nbsp;Water or other drinks are not needed. Do not store the freeze-dried tablet outside the blister card for future use.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">If You Have Taken Too Much Vydura<\/h2>\n\n\n\n<p>Talk to a doctor or pharmacist or go to the hospital immediately.&nbsp;Take the medicine package and this leaflet with you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Take Vydura<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are taking Vydura to prevent&nbsp;migraines&nbsp;and miss a&nbsp;dose, take the next&nbsp;dose&nbsp;at the usual time.<\/li><li>Do not take a double&nbsp;dose&nbsp;to make up for a missed&nbsp;dose.<\/li><\/ul>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible Vydura Side Effects<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Stop using Vydura<\/strong> <strong>and contact your doctor immediately if you develop signs of an&nbsp;allergic reaction,<\/strong>&nbsp;eg.&nbsp;severe skin rash or shortness of breath.&nbsp;Allergic reactions to VYDURA are uncommon (may affect up to 1 in 100 users).<\/p>\n\n\n\n<p><strong>A common&nbsp;Vyduraside effect (which may affect up to 1 in 10 users) is nausea.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How Vydura Should Be Stored<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children.<\/li><li>Use before the expiry date stated on the carton and blister card after EXP.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Store at a maximum of 30 \u00b0C.&nbsp;Store in the original blister.&nbsp;Moisture sensitive.<\/li><li>Medicines must not be thrown into the drain or among household waste.&nbsp;Ask the pharmacist how to dispose of medications that are no longer used.&nbsp;These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is rimegepant.\u00a0Each freeze-dried tablet contains 75 mg rimegepant (as sulfate).<\/li><li>Other ingredients are gelatin, mannitol, mint flavor, and sucralose.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance And Package Sizes Of The Medicine<\/h2>\n\n\n\n<p>Vydura 75 mg lyophilized tablets are white to off-white, round, and embossed with the symbol<a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20210212000017#\" rel=\"noopener\"><\/a><\/p>\n\n\n\n<p>Package sizes:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>2 x 1 freeze-dried tablet in perforated single-dose blisters in wallet packaging.<\/li><li>8 x 1 freeze-dried tablet in perforated single-dose blisters.<\/li><li>16 x 1 freeze-dried tablet in perforated single-dose blisters.<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>Biohaven Pharmaceutical Ireland DAC<\/p>\n\n\n\n<p>6th Floor, South Bank House<\/p>\n\n\n\n<p>Barrow Street<\/p>\n\n\n\n<p>Dublin D04 TR29<\/p>\n\n\n\n<p>Ireland<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>HiTech Health Limited<\/p>\n\n\n\n<p>5-7 Main Street<\/p>\n\n\n\n<p>Black Rock<\/p>\n\n\n\n<p>Co.&nbsp;Dublin<\/p>\n\n\n\n<p>A94 R5Y4<\/p>\n\n\n\n<p>Ireland<\/p>\n\n\n\n<p>Millmount Healthcare Limited<\/p>\n\n\n\n<p>Block-7, City North Business Campus<\/p>\n\n\n\n<p>The stem<\/p>\n\n\n\n<p>Co.&nbsp;Meath<\/p>\n\n\n\n<p>K32 YD60<\/p>\n\n\n\n<p>Ireland<\/p>\n\n\n\n<p><strong>Contact the representative of the Marketing Authorization Holder if you would like to know more about this medicine:<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgi\u00eb\/Belgique\/Belgien<\/strong><strong>Luxembourg\/Luxembourg<\/strong>Pfizer NV\/SATel\/Tel: +32 (0)2 554 62 11<\/td><td><strong>Lithuania<\/strong>Pfizer Luxembourg SARL branches in LithuaniaTel.&nbsp;+370 5 251 4000<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Pfizer Luxembourg \u0421\u0410\u0420\u041b, \u041a\u043b\u043e\u043d \u0411\u0443\u043b\u0433\u0430\u0440\u0438\u044fPhone: +359 2 970 4333<\/td><td><strong>Magyarorsz\u00e1g<\/strong>Pfizer Kft.Tel.: + 36 1 488 37 00<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Pfizer, coil.&nbsp;s iPhone: +420 283 004 111<\/td><td><strong>Malta<\/strong>Vivian Corporation Ltd.Tel.: +356 21344610<\/td><\/tr><tr><td><strong>Denmark<\/strong>Pfizer ApSPhone: +45 44 20 11 00<\/td><td><strong>The Netherlands<\/strong>Pfizer by phone: +31 (0) 800 63 34 636<\/td><\/tr><tr><td><strong>Deutschland<\/strong>PFIZER PHARMA GmbHPhone: +49 (0)30 550055-51000<\/td><td><strong>Norway<\/strong>Pfizer iPhone: +47 67 52 61 00<\/td><\/tr><tr><td><strong>Estonia<\/strong>Pfizer Luxembourg SARL Eesti branch phone: +372 666 7500<\/td><td><strong>Austria<\/strong>Pfizer Corporation Austria Ges.mbHPhone: +43 (0)1 521 15-0<\/td><\/tr><tr><td><strong>Greece<\/strong>Pfizer \u0395\u03bb\u03bb\u03ac\u03c2 \u0391.\u0395.Tel.: +30 210 6785800<\/td><td><strong>Polish<\/strong>Pfizer Polska Sp.&nbsp;z o. oTel.: +48 22 335 61 00<\/td><\/tr><tr><td><strong>Spain<\/strong>Pfizer, SLPhone: +34 91 490 99 00<\/td><td><strong>Portugal<\/strong>Laborat\u00f3rios Pfizer, Lda.Phone: +351 21 423 5500<\/td><\/tr><tr><td><strong>France<\/strong>PfizerTel: +33 (0)1 58 07 34 40<\/td><td><strong>Romania<\/strong>Pfizer Romania SRLPhone: +40 (0) 21 207 28 00<\/td><\/tr><tr><td><strong>Hrvatska<\/strong>Pfizer Croatia dooPhone: +385 1 3908 777<\/td><td><strong>Slovenija<\/strong>Pfizer Luxembourg SARLPfizer, a branch of marketing, LjubljanaTel.: +386 (0)1 52 11 400<\/td><\/tr><tr><td><strong>Ireland<\/strong>Pfizer Healthcare IrelandTel: +1800 633 363 (toll-free)Phone: +44 (0)1304 616161<\/td><td><strong>Slovenian Republic<\/strong>Pfizer Luxembourg SARL, organiza\u010dn\u00e1 zlo\u017ekaPhone: + 421 2 3355 5500<\/td><\/tr><tr><td><strong>Iceland<\/strong>Icepharma hf.Telephone: +354 540 8000<\/td><td><strong>Finland\/Finland<\/strong>Pfizer OyPhone\/Tel: +358 (0)9 430 040<\/td><\/tr><tr><td><strong>Italy<\/strong>Pfizer SrlPhone: +39 06 33 18 21<\/td><td><strong>Sweden<\/strong>Pfizer ABPhone: +46 (0)8 550 520 00<\/td><\/tr><tr><td><strong>Cyprus<\/strong>Pfizer \u0395\u03bb\u03bb\u03ac\u03c2 \u0391.\u0395.&nbsp;(Cyprus Branch)Tel.: +357 22817690<\/td><td><strong>United Kingdom (Northern Ireland)<\/strong>Pfizer LimitedPhone: +44 (0) 1304 616161<\/td><\/tr><tr><td><strong>Latvia<\/strong>Pfizer Luxembourg SARL branch in LatviaPhone: + 371 670 35 775<\/td><td>&nbsp;<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><\/h2>\n","protected":false},"excerpt":{"rendered":"<p>VYDURA contains the active substance rimegepant, which prevents the activity of a substance in the body called calcitonin gene-related\u00a0peptide\u00a0(CGRP).\u00a0People with\u00a0migraines\u00a0may have elevated levels of CGRP.\u00a0Rimegepant binds to the receptor for CGRP and thereby reduces the ability of CGRP to also bind to the receptor.\u00a0This reduces CGRP activity and has two effects:<\/p>\n","protected":false},"author":2,"featured_media":47737,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[27745,27748,27747,27749,27753,27752,27744,27750,27746,27751],"class_list":["post-31406","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicines","category-v","tag-rimegepant","tag-rimegepant-side-effects","tag-rimegepant-tablet","tag-vydura","tag-vydura-side-effects","tag-vydura-tablet","tag-what-is-rimegepant","tag-what-is-vydura","tag-what-rimegepant-is-used-for","tag-what-vydura-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31406","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=31406"}],"version-history":[{"count":33,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31406\/revisions"}],"predecessor-version":[{"id":47740,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31406\/revisions\/47740"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media\/47737"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=31406"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=31406"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=31406"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}