0.4 mg;\u00a00.56 mg and 1.2 mg respectively\u00a0powder and liquid for\u00a0injection, solution
vosoritide<\/p>\n\n\n\n
What Voxzogo is<\/strong><\/p>\n\n\n\n Voxzogo contains the active substance vosoritide. It is similar to a protein in the body called C-type natriuretic peptide (CNP). Vosoritide is produced using recombinant technology, which involves bacteria that have been modified to contain the gene that produces the protein et.<\/p>\n\n\n\n What Voxzogo is used for<\/strong><\/p>\n\n\n\n This medicine is used to treat achondroplasia in patients aged 2 years and older, whose bones are still growing.\u00a0Achondroplasia is a genetic condition that affects the growth of almost all bones in the body, including the skull, spine, arms, and legs, leading to short stature with a characteristic appearance.<\/p>\n\n\n\n The medicine is only intended for use in achondroplasia caused by mutations in the FGFR3<\/em> gene that have been confirmed via genetic testing.<\/p>\n\n\n\n How Voxzogo works<\/strong><\/p>\n\n\n\n The active substance in Voxzogo acts directly on the growth points of the skeleton to promote new bone growth. Talk to your doctor before using Voxzogo<\/p>\n\n\n\n If any of this applies to you or your child, or if you are not sure, talk to your doctor before using Voxzogo.<\/p>\n\n\n\n Effects on blood pressure et<\/p>\n\n\n\n Voxzogo can lower\u00a0blood pressure\u00a0et.\u00a0It can make you feel dizzy, nauseous, or tired.\u00a0Blood pressure\u00a0usually returns to normal within 90 minutes after\u00a0injection\u00a0with Voxzogo.\u00a0If these effects occur and are severe, talk to a doctor.<\/p>\n\n\n\n If you drink plenty of fluids at the time of\u00a0injection, the likelihood of these effects may decrease.\u00a0You or your child are advised to eat a light snack and drink a glass of liquid (eg water, milk, or juice) about 30 minutes before\u00a0injection\u00a0one.<\/p>\n\n\n\n There is not enough information on the use of this medicine in children under 2 years of age, so it is not recommended.<\/a><\/p>\n\n\n\n Tell the doctor if you or your child are taking, have recently taken, or might be taking other medicines.<\/p>\n\n\n\n If you or your child are being treated with this medicine and are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, consult a doctor before using this medicine.<\/p>\n\n\n\n It is not recommended to use this medicine during pregnancy and breastfeeding.<\/a><\/p>\n\n\n\n This medicine may make you feel dizzy, tired, or nauseous soon after the\u00a0injection.\u00a0If this happens, you should not drive, cycle, do physical activity, or use machinery for about an hour after the\u00a0injection\u00a0or until you feel better.<\/p>\n\n\n\n This medicine contains less than 1 mmol (23 mg) of\u00a0sodium\u00a0per\u00a0dose, i.e. it is almost “sodium-free”. A healthcare provider should give an injection with Voxzogo. Do not give your child an injection of Voxzogo until you have received appropriate training from a healthcare professional.<\/p>\n\n\n\n Always use this medicine as directed by your doctor. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n Dose<\/strong><\/p>\n\n\n\n Your doctor will choose the right dose depending on your or your child’s body weight. The doctor will tell you how much of the solution for injection to inject. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n You or your child should eat a light snack and drink a glass of water, milk, or juice about 30 minutes before\u00a0injection\u00a0one.\u00a0This can reduce\u00a0side effects\u00a0such as dizziness, fatigue, or nausea.<\/p>\n\n\n\n How to use Voxzogo<\/strong><\/p>\n\n\n\n Inject Voxzogo slowly under the skin ( subcutaneous injection ).<\/p>\n\n\n\n Injection one should be given at approximately the same time each day.<\/p>\n\n\n\n It would help if you gave the\u00a0injection\u00a0at a different site each day and not use the same place two days in a row.\u00a0Do not inject this medicine into skin blemishes, scars, birthmarks, or areas where the skin is tender, red, stiff, or bruised.<\/p>\n\n\n\n If you have injected too much Voxzogo, contact your doctor immediately.<\/a><\/p>\n\n\n\n If you or your child miss a\u00a0dose, the\u00a0injection\u00a0must\u00a0still be given if it is within 12 hours of the scheduled time.\u00a0If more than 12 hours have passed since\u00a0dose\u00a0one should have been given, the missed\u00a0dose\u00a0one should not be injected.\u00a0Wait until the next day and continue with the usual\u00a0dose\u00a0at the usual time.<\/p>\n\n\n\n
<\/a><\/p>\n\n\n\nWhat you need to know before using Voxzogo<\/h2>\n\n\n\n
Do not use Voxzogo<\/h2>\n\n\n\n
Warnings and precautions<\/h2>\n\n\n\n
Children and young people<\/h2>\n\n\n\n
Other medicines and Voxzogo<\/h2>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n
Ability to drive, cycle and use machines<\/h2>\n\n\n\n
Voxzogo contains sodium<\/h2>\n\n\n\n
<\/p>\n\n\n\nHow to use Voxzogo<\/h2>\n\n\n\n
If you have used too much Voxzogo<\/h2>\n\n\n\n
If you forget to use Voxzogo<\/h2>\n\n\n\n
If you stop using Voxzogo<\/h2>\n\n\n\n