{"id":31393,"date":"2022-11-09T07:12:47","date_gmt":"2022-11-09T07:12:47","guid":{"rendered":"https:\/\/zeepedia.com\/?p=31393"},"modified":"2022-11-10T07:44:29","modified_gmt":"2022-11-10T07:44:29","slug":"vosevi","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/vosevi\/","title":{"rendered":"Vosevi &#8211; Sofosbuvir\/velpatasvir\/voxilaprevir uses, dose and side effects"},"content":{"rendered":"\n<p>400 mg\/100 mg\/100 mg film-coated tablets, 200 mg\/50 mg\/50 mg&nbsp;film-coated tablets<br>sofosbuvir\/velpatasvir\/voxilaprevir<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Vosevi is and what it is used for<\/h2>\n\n\n\n<p>Vosevi is a medicine that contains the active substances sofosbuvir, velpatasvir, and voxilaprevir in a single tablet.\u00a0It is given to treat\u00a0chronic\u00a0(long-term) viral infection of the liver called\u00a0hepatitis\u00a0C in patients aged 12 years and older and weighing at least 30 kg.<\/p>\n\n\n\n<p>The active substances in the medicine work together by blocking three different&nbsp;proteins&nbsp;that the&nbsp;hepatitis&nbsp;C&nbsp;virus&nbsp;needs to grow and reproduce, which means that the&nbsp;infection&nbsp;is removed from the body.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Vosevi<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Vosevi<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If you are allergic<\/strong>\u00a0to sofosbuvir, velpatasvir, voxilaprevir, or any of the other ingredients of this medicine (listed in section 6 of this leaflet).<br>\u2192\u00a0If this applies to you,\u00a0do not take\u00a0Vosevi and tell your doctor\u00a0immediately.<\/li><li>If you are currently taking any of the following medicines:<ul><li>rifampicin\u00a0and\u00a0rifabutin\u00a0(\u00a0antibiotics\u00a0used to treat\u00a0infections, including\u00a0tuberculosis\u00a0)<\/li><li>St. John&#8217;s wort\u00a0(\u00a0Hypericum perforatum\u00a0) (a herbal medicine used to treat mild depression)<\/li><li>carbamazepine, phenobarbital,\u00a0and\u00a0phenytoin\u00a0(medicines used to treat\u00a0epilepsy\u00a0and prevent seizures)<\/li><li>rosuvastatin\u00a0(a medicine used to treat high blood\u00a0cholesterol\u00a0or reduce the risk of certain cardiovascular diseases)<\/li><li>dabigatran etexilate\u00a0(a medicine used to prevent blood clots)<\/li><li>ethinylestradiol-containing medicines, including many contraceptives<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>have other liver problems<\/strong>\u00a0besides\u00a0hepatitis\u00a0C, for example<ul><li><strong>currently have or have previously had a\u00a0hepatitis\u00a0B\u00a0virus infection<\/strong>,\u00a0as\u00a0your\u00a0doctor may need to monitor you more closely<\/li><li>has undergone a liver transplant<\/li><\/ul><\/li><li>are undergoing treatment for\u00a0HIV\u00a0(human immunodeficiency virus)\u00a0infection<strong>,<\/strong>\u00a0as your doctor may need to monitor you more closely.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Vosevi if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you are currently taking, or have taken in recent months, the medicine\u00a0amiodarone\u00a0to treat irregular heartbeats, as it may cause your heart rate to drop to a life-threatening level.\u00a0The doctor may consider alternative treatments if you have been taking this medicine.\u00a0If you need treatment with Vosevi, extra heart monitoring may be necessary.<\/li><li>you have\u00a0diabetes.\u00a0Your blood sugar levels may need to be monitored more closely and\/or your diabetes medicines may need to be adjusted after you start taking Vosevi.\u00a0In some diabetic patients, blood sugar levels have fallen (hypoglycemia) after treatment with medicines such as Vosevi has been started.<\/li><\/ul>\n\n\n\n<p><strong>Tell the doctor immediately<\/strong>\u00a0if you are currently taking, or have taken in the past months, any medicines for heart problems you experience during treatment:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>slow or irregular heartbeats, or heart rhythm problems<\/li><li>shortness of breath or worsening of existing shortness of breath<\/li><li>chest pains<\/li><li>dizziness<\/li><li>palpitation<\/li><li>that you almost faint, or pass out<\/li><\/ul>\n\n\n\n<p><strong>Blood samples<\/strong><\/p>\n\n\n\n<p>The doctor will check your blood before, during, and after treatment with Vosevi.\u00a0This is to:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The doctor should be able to decide if you should take Vosevi and for how long.<\/li><li>The doctor must be able to confirm that the treatment has worked and that you no longer carry the\u00a0hepatitis\u00a0C\u00a0virus.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children under 12 years of age and weighing less than 30 kg.\u00a0The use of Vosevi in \u200b\u200bthese patients has not yet been studied.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Vosevi<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Talk to your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Some medicines must not be taken together with Vosevi.&nbsp;<\/strong>If you take Vosevi with any of these, the medicines may not work as well or any&nbsp;side effects&nbsp;may get worse:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>rifampicin<\/strong>\u00a0and\u00a0<strong>rifabutin<\/strong>\u00a0(\u00a0antibiotics\u00a0used to treat\u00a0infections, including\u00a0tuberculosis\u00a0)<\/li><li>St. John&#8217;s wort\u00a0(\u00a0Hypericum perforatum\u00a0) (a herbal medicine used to treat mild depression)<\/li><li>carbamazepine, phenobarbital,\u00a0and\u00a0phenytoin\u00a0(medicines used to treat\u00a0epilepsy\u00a0and prevent seizures)<\/li><li>rosuvastatin\u00a0(a medicine used to treat high blood\u00a0cholesterol\u00a0or reduce the risk of certain cardiovascular diseases)<\/li><li>dabigatran etexilate\u00a0(a medicine used to prevent blood clots)<\/li><li>ethinylestradiol-containing medicines, including many contraceptives<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor or pharmacist<\/strong>&nbsp;if you are taking any of the medicines below:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>amiodarone\u00a0<\/strong>used to treat irregular heartbeats<\/li><li>rifapentine\u00a0(an\u00a0antibiotic\u00a0used to treat\u00a0infections, including\u00a0tuberculosis\u00a0)<\/li><li>oxcarbazepine\u00a0(a medicine used to treat\u00a0epilepsy\u00a0and prevent epileptic seizures)<\/li><li>tenofovir disoproxil fumarate,\u00a0or any medicine containing tenofovir disoproxil fumarate, used to\u00a0treat\u00a0HIV\u00a0infection<\/li><li>atanazevir, efavirenz\u00a0or\u00a0lopinavir,\u00a0used to\u00a0treat\u00a0HIV\u00a0infection<\/li><li>digoxin,\u00a0which is used to treat heart disease<\/li><li>modafinil,\u00a0which is used to treat sleep disorders<\/li><li>atorvastatin, pravastatin,\u00a0or\u00a0<strong>other statins,<\/strong>\u00a0used to treat high\u00a0cholesterol<\/li><li><strong>ciclosporin,<\/strong>\u00a0which is used to\u00a0suppress\u00a0the immune system<\/li><\/ul>\n\n\n\n<p>If you take Vosevi together with any of these, the medicines may not work as well or any&nbsp;side effects&nbsp;may get worse.&nbsp;The doctor may need to give you another medicine or change the dose of medicine you are taking.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Consult a doctor or pharmacist<\/strong>\u00a0if you are taking medicines used to treat\u00a0<strong>stomach ulcers<\/strong>, heartburn, or acid reflux\u00a0as they may reduce the amount of velpatasvir in the blood.\u00a0These are:<ul><li>antacids (eg aluminum\/magnesium hydroxide or\u00a0calcium carbonate\u00a0).\u00a0These should be taken at least 4 hours before or 4 hours after Vosevi<\/li><li>proton pump inhibitors\u00a0(eg omeprazole, lansoprazole, rabeprazole, pantoprazole and esomeprazole).\u00a0If you need high\u00a0doses\u00a0of these medicines, your doctor may give you another medicine or change the dose of medicine you are taking<\/li><li>H\u00a02\u00a0-receptor antagonists (eg famotidine, cimetidine, nizatidine, or ranitidine).\u00a0If you need high\u00a0doses\u00a0of these medicines, your doctor may give you another medicine or change the dose of medicine you are taking.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>These medicines can reduce the amount of Vosevi in \u200b\u200bthe blood.\u00a0If you are taking any of these medicines, the doctor will either give you another medicine for\u00a0stomach ulcers, heartburn, or acid reflux or recommend how and when to take the medicine.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Ask your doctor or pharmacist<\/strong>&nbsp;if you are taking&nbsp;<strong>warfarin&nbsp;<\/strong><strong>or other similar medicines<\/strong>&nbsp;called&nbsp;vitamin&nbsp;K&nbsp;antagonists&nbsp;and used to thin the blood.&nbsp;Your doctor may need to test your blood more often to check your blood&#8217;s clotting ability.<\/li><li>The function of your liver may change with the treatment of&nbsp;hepatitis&nbsp;C and therefore may affect other medicines (eg medicines used to&nbsp;suppress&nbsp;your immune system, etc.).&nbsp;Your doctor may need to monitor these other medicines that you are taking closely and adjustments may need to be made after treatment with Vosevi is started.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant, think you may be pregnant, are breastfeeding, or are planning to have a baby, consult your doctor before using this medicine.<\/p>\n\n\n\n<p><strong>Pregnancy<\/strong><\/p>\n\n\n\n<p><strong>Vosevi is not recommended during pregnancy.&nbsp;<\/strong>&nbsp;The effects of Vosevi during pregnancy are unknown.<\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p><strong>Do not breastfeed during treatment with Vosevi.\u00a0<\/strong>Some of the active substances in Vosevi can pass into breast milk.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Vosevi should not affect your ability to drive or use any tools or machines.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Vosevi contains lactose<\/h2>\n\n\n\n<p><strong>Tell your doctor if you are lactose intolerant or intolerant to other sugars.\u00a0<\/strong>Vosevi contains\u00a0lactose monohydrate.\u00a0If you have an intolerance to certain sugars, you should consult your doctor before taking this medication.<\/p>\n\n\n\n<p><strong>Vosevi contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;of sodium&nbsp;per tablet, i.e. it is almost &#8216;sodium-free&#8217;.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Vosevi<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Recommended&nbsp;dose<\/strong><\/p>\n\n\n\n<p>The recommended\u00a0dose\u00a0of Vosevi is\u00a0<strong>one\u00a0<\/strong>\u00a0<strong>400 mg\/100 mg\/100 mg tablet<\/strong><\/p>\n\n\n\n<p><strong>or two 200 mg\/50 mg\/50 mg tablets taken once daily for 8 or 12 weeks<\/strong>.<\/p>\n\n\n\n<p><strong>Take Vosevi as directed by your doctor.<\/strong><\/p>\n\n\n\n<p>Swallow the tablet(s) whole with food.\u00a0Do not chew, crush or split the tablet as it tastes very bitter.<\/p>\n\n\n\n<p><strong>Kidney problems<\/strong><\/p>\n\n\n\n<p>Tell the doctor if you\u00a0<strong>have kidney problems<\/strong>\u00a0or if you are on\u00a0<strong>kidney\u00a0dialysis<\/strong>, as Vosevi has not been fully tested in patients with severe kidney problems.<\/p>\n\n\n\n<p><strong>Liver problems<\/strong><\/p>\n\n\n\n<p>Vosevi should not be used if you have moderate or severe liver problems.<\/p>\n\n\n\n<p><strong>If you take an antacid,<\/strong>&nbsp;take it at least 4 hours before or at least 4 hours after Vosevi.<\/p>\n\n\n\n<p><strong>If you vomit after taking Vosevi<\/strong>, it may affect the amount of Vosevi in \u200b\u200byour blood.\u00a0This may cause Vosevi to not work as well.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you vomit\u00a0<strong>less than 4 hours after<\/strong>\u00a0taking Vosevi, take another\u00a0dose.<\/li><li>If you vomit\u00a0<strong>more than 4 hours after<\/strong>\u00a0taking Vosevi, you do not need to take another\u00a0dose\u00a0until you are due to take the next\u00a0dose\u00a0according to the treatment schedule.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you use too much Vosevi&nbsp;<\/h2>\n\n\n\n<p>If you accidentally take more than the recommended\u00a0dose\u00a0of Vosevi, the risk of\u00a0side effects\u00a0from this medicine may increase (see section 4\u00a0<em>Possible\u00a0side effects\u00a0)<\/em>.<\/p>\n\n\n\n<p>Contact a doctor, hospital, or Poisons Information Center immediately for advice.\u00a0Take the jar of tablets with you so that you can easily describe what you have taken.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Vosevi<\/h2>\n\n\n\n<p>You mustn&#8217;t miss a\u00a0dose\u00a0of this medicine.<\/p>\n\n\n\n<p>If you miss a\u00a0dose, calculate how long it has been since you last took Vosevi:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If you notice less than 18 hours<\/strong>\u00a0after the time you usually take Vosevi, you must take the missed\u00a0dose\u00a0as soon as possible.\u00a0Then take the next\u00a0dose\u00a0at the usual time.<\/li><li><strong>If it has been 18 hours or more<\/strong>\u00a0after the time you usually take Vosevi, wait and take the next\u00a0dose\u00a0at the usual time.\u00a0Do not take a double\u00a0dose\u00a0(two\u00a0doses\u00a0close to each other) to compensate for a forgotten\u00a0dose.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Do not stop taking Vosevi<\/h2>\n\n\n\n<p>Do not stop taking this medicine unless your doctor tells you to.\u00a0You must complete the entire course of treatment to give the medicine the best conditions for treating an\u00a0infection\u00a0with the\u00a0hepatitis\u00a0C\u00a0virus.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be serious.<\/strong><\/p>\n\n\n\n<p><strong>Stop taking Vosevi and see a doctor immediately if you experience any of the following symptoms:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swelling of the face, lips, tongue, or throat (\u00a0angioedema\u00a0) (\u00a0an uncommon\u00a0side effect\u00a0\u2013 may affect up to 1 in 100 people\u00a0)<\/li><li>Widespread, severe rash with scaly skin that may be accompanied by fever,\u00a0flu-like symptoms, blisters in the mouth, eyes, and\/or genitals (Stevens-Johnson syndrome) (\u00a0<em>has been reported &#8211; occurring in an unknown number of users<\/em>\u00a0)<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;that may occur<\/strong><\/p>\n\n\n\n<p><strong>Very common&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p><em>(may affect more than 1 in 10 users)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache<\/li><li>diarrhea<\/li><li>nausea<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p><em>(may affect up to 1 in 10 users)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>stomach pain<\/li><li>decreased appetite<\/li><li>vomiting<\/li><li>muscle pain (&nbsp;myalgia&nbsp;)<\/li><li>abnormal results on laboratory tests of liver function (total&nbsp;bilirubin&nbsp;)<\/li><li>rash<\/li><\/ul>\n\n\n\n<p><strong>Less common&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p><em>(may affect up to 1 in 100 users)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>muscle spasms<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Vosevi<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the can and carton after &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special temperature instructions.&nbsp;Store in the original packaging.&nbsp;Moisture sensitive.&nbsp;Close the jar well.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are sofosbuvir, velpatasvir and voxilaprevir.&nbsp;Each film-coated tablet contains 400 mg sofosbuvir, 100 mg velpatasvir and 100 mg voxilaprevir or 200 mg sofosbuvir, 50 mg velpatasvir and 50 mg voxilaprevir.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Other ingredients are tablet core: Colloidal\u00a0anhydrous silica, copovidone, croscarmellose sodium (E468)(see section 2 of this leaflet),\u00a0lactose monohydrate\u00a0(see section 2 of this leaflet), magnesium stearate, microcrystalline cellulose (E460).<br>Film coating: Black iron oxide (E172), red iron oxide (E172), yellow iron oxide (E172), macrogol (E1521), polyvinyl alcohol (E1203), talc (E553b), titanium dioxide (E171).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Vosevi 400 mg\/100 mg\/100 mg film-coated tablets are beige, capsule-shaped tablets, debossed with \u201cGSI\u201d on one side and \u201c3\u201d on the other.\u00a0The tablet is 20 mm long and 10 mm wide.<\/p>\n\n\n\n<p>Vosevi 200 mg\/50 mg\/50 mg film-coated tablets are beige, oval tablets, debossed with \u201cGSI\u201d on one side and \u201cSVV\u201d on the other.\u00a0The tablet is 15 mm long and 8 mm wide.<\/p>\n\n\n\n<p>The tablets are packaged in plastic jars with child-resistant lids.&nbsp;Each jar contains a silica gel desiccant that must be kept in the jar to protect the tablets.&nbsp;The silica gel desiccant is in a separate bag or container and should not be swallowed.<\/p>\n\n\n\n<p>The following pack sizes are available for both 400 mg\/100 mg\/100 mg and 200 mg\/50 mg\/50 mg film-coated tablets:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>outer cartons containing 1 jar of 28 film-coated tablets.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Gilead Sciences Ireland UC<\/p>\n\n\n\n<p>Carrigtohill<\/p>\n\n\n\n<p>County Cork, T45 DP77<\/p>\n\n\n\n<p>Ireland<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Gilead Sciences Ireland UC<\/p>\n\n\n\n<p>IDA Business &amp; Technology Park<\/p>\n\n\n\n<p>Carrigtohill<\/p>\n\n\n\n<p>County Cork<\/p>\n\n\n\n<p>Ireland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vosevi is a medicine that contains the active substances sofosbuvir, velpatasvir and voxilaprevir in a single tablet.\u00a0It is given to treat\u00a0chronic\u00a0(long-term) viral infection of the liver called\u00a0hepatitis\u00a0C in patients aged 12 years and older and weighing at least 30 kg.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[4083,27809,4086,27811,27805,27806,27813,27815,4084,4087,27807,27812,13927,27810,27808,27814],"class_list":["post-31393","post","type-post","status-publish","format-standard","hentry","category-medicines","category-v","tag-sofosbuvir","tag-sofosbuvir-tablet","tag-velpatasvir","tag-velpatasvir-tablet","tag-vosevi","tag-vosevi-tablet","tag-voxilaprevir","tag-voxilaprevir-tablet","tag-what-is-sofosbuvir","tag-what-is-velpatasvir","tag-what-is-vosevi","tag-what-is-voxilaprevir","tag-what-sofosbuvir-is-used-for","tag-what-velpatasvir-is-used-for","tag-what-vosevi-is-used-for","tag-what-voxilaprevir-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31393","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=31393"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31393\/revisions"}],"predecessor-version":[{"id":31515,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/31393\/revisions\/31515"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=31393"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=31393"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=31393"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}