{"id":30845,"date":"2022-11-06T16:23:16","date_gmt":"2022-11-06T16:23:16","guid":{"rendered":"https:\/\/zeepedia.com\/?p=30845"},"modified":"2022-11-07T09:35:05","modified_gmt":"2022-11-07T09:35:05","slug":"vizamyl","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/vizamyl\/","title":{"rendered":"VIZAMYL &#8211; Flutemetamol uses, dose and side effects"},"content":{"rendered":"\n<p>400 MBq\/ml\u00a0solution for injection,<br>flutemetamol (\u00a0<sup>18<\/sup>\u00a0F)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What VIZAMYL is and what it is used for<\/h2>\n\n\n\n<p>VIZAMYL contains the active substance flutemetamol (&nbsp;<sup>18<\/sup>&nbsp;F) and is used to help diagnose&nbsp;Alzheimer&#8217;s disease&nbsp;and other causes of memory loss.&nbsp;This medicine is a radiopharmaceutical product used to make a diagnosis.<\/p>\n\n\n\n<p>VIZAMYL is used to help diagnose\u00a0Alzheimer&#8217;s disease\u00a0and other causes of memory loss and is given to adults with memory problems before they undergo a type of brain scan called positron emission tomography (PET scan).\u00a0This exam, combined with other brain function tests, can help your doctor determine whether you may have beta-amyloid\u00a0plaques\u00a0in your brain.\u00a0Beta-amyloid\u00a0plaques\u00a0are deposits that are sometimes present in the brains of people with dementia (such as\u00a0Alzheimer&#8217;s disease\u00a0).<\/p>\n\n\n\n<p>You should discuss the results of the examination with the doctor who ordered the scan.<\/p>\n\n\n\n<p>The use of Vizamyl involves exposure to small amounts of radioactivity.<\/p>\n\n\n\n<p>The doctor and the nuclear medicine physician have judged that the benefit of the examination with the radioactive substance outweighs the risk of being exposed to these small amounts of radiation.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you receive VIZAMYL\u00a0\u00a0<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">VIZAMYL must not be used:&nbsp;<\/h2>\n\n\n\n<p>&#8211; If you are allergic to flutemetamol (&nbsp;<sup>18<\/sup>&nbsp;F) or any other ingredient in this medicine (listed in section 6).<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor before receiving VIZAMYL if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have kidney problems<\/li><li>have liver problems<\/li><li>are pregnant or think you may be pregnant<\/li><li>breastfeeding.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>VIZAMYL is not intended for children and adolescents under the age of 18.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and VIZAMYL<\/h2>\n\n\n\n<p>Tell the nuclear medicine doctor if you are taking, have recently taken, or might be taking any other medicines as they may affect the images obtained from the brain scan.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>You must tell the isotope doctor before receiving VIZAMYL if there is any possibility that you are pregnant, if you have missed your period or if you are breastfeeding.\u00a0If you are unsure, you must discuss it with the isotope doctor who will lead the examination.<\/p>\n\n\n\n<p>If you are pregnant<\/p>\n\n\n\n<p>The isotope doctor will only give you this medicine during pregnancy if the expected benefit outweighs the risks.<\/p>\n\n\n\n<p>If you are breast-feeding<\/p>\n\n\n\n<p>You must take a break from breastfeeding for 24 hours after&nbsp;injection&nbsp;one.&nbsp;Express the breast milk during this period and discard it.&nbsp;Ask the radiologist for advice before receiving this medicine.<\/p>\n\n\n\n<p>You should avoid close contact with small children for 24 hours after&nbsp;injection&nbsp;a.<\/p>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, consult your nuclear medicine physician before receiving this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>VIZAMYL can cause transient dizziness which may affect your ability to drive or use machines.\u00a0You should avoid driving, operating machinery, or engaging in other risky activities until these effects have completely worn off.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">VIZAMYL contains alcohol (ethanol) and sodium<\/h2>\n\n\n\n<p>This medicine contains alcohol (\u00a0ethanol\u00a0).\u00a0Each\u00a0dose\u00a0contains up to 552 mg of alcohol, equivalent to approximately 14 ml of beer or 6 ml of wine.\u00a0This can be harmful to people who are addicted to alcohol.\u00a0It should be considered for pregnant and lactating women as well as people with liver problems or\u00a0epilepsy.<\/p>\n\n\n\n<p>VIZAMYL contains a maximum of 41 mg\u00a0sodium\u00a0(the main component of table salt) per\u00a0dose.\u00a0This corresponds to about 2% of the WHO&#8217;s highest recommended daily intake of\u00a0sodium.\u00a0This should be taken into account by patients prescribed a low-salt diet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How VIZAMYL is used<\/h2>\n\n\n\n<p>There are strict regulations on the use, handling, and destruction of radiopharmaceuticals.<\/p>\n\n\n\n<p>VIZAMYL will only be used in specially controlled areas.\u00a0This product is handled and given to you by people who are trained and qualified to use it safely.\u00a0They will provide you with the necessary information regarding the examination.<\/p>\n\n\n\n<p>Your isotope doctor may ask you to drink plenty of water before the examination time and for 24 hours after the study to urinate as often as possible, which will help you remove the medicine from your body.<\/p>\n\n\n\n<p><strong>Dose&nbsp;<\/strong><\/p>\n\n\n\n<p>The isotope doctor who conducts the examination decides how much VIZAMYL you will receive.&nbsp;The doctor will use the smallest amount needed.<\/p>\n\n\n\n<p>The amount most often recommended for an adult is 185 MBq (megabecquerel, the unit used to measure radioactivity).<\/p>\n\n\n\n<p><strong>How VIZAMYL is given and how the examination is carried out<\/strong><\/p>\n\n\n\n<p>VIZAMYL is given as an&nbsp;injection&nbsp;into a vein (&nbsp;intravenous&nbsp;injection&nbsp;), accompanied by saline so that the entire&nbsp;dose&nbsp;is delivered safely.<\/p>\n\n\n\n<p>One&nbsp;injection&nbsp;is enough for the examination that your doctor needs.<\/p>\n\n\n\n<p><strong>Duration of the survey<\/strong><\/p>\n\n\n\n<p>After a VIZAMYL\u00a0injection, it takes about 90 minutes before a brain scan can be done. The Isotope doctor will inform you of how long the examination usually lasts.<\/p>\n\n\n\n<p><strong>After you have had a VIZAMYL\u00a0injection, you should:<\/strong>\u00a0<\/p>\n\n\n\n<p>Avoid close contact with small children and pregnant women for 24 hours after&nbsp;injection&nbsp;a.<\/p>\n\n\n\n<p>The isotope doctor will tell you if you need to take any special precautions while receiving this medicine.&nbsp;Contact the isotope doctor if you have any questions<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have received too much VIZAMYL<\/h2>\n\n\n\n<p>It is unlikely that you will get an overdose because you will only be given one\u00a0dose\u00a0of VIZAMYL by the isotope doctor under controlled conditions.<\/p>\n\n\n\n<p>If an overdose should nevertheless occur, you will receive appropriate treatment.\u00a0The treatment involves speeding up the passage of urine and feces, so that the radioactivity disappears as quickly as possible from your body.<\/p>\n\n\n\n<p>If you have any further questions about VIZAMYL, contact the isotope doctor who is conducting the examination.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.\u00a0The following\u00a0side effects\u00a0may occur with this medicine:<\/p>\n\n\n\n<p><strong>Serious&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>Tell your doctor straight away if you notice any of the following as you may need&nbsp;urgent&nbsp;medical treatment:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic reactions &#8211; symptoms may include swelling of the face or eyes, pale, itchy, or tight skin or rash, shortness of breath, chest tightness, throat irritation, or vomiting.\u00a0These\u00a0side effects\u00a0are less common and may occur in up to 1 in 100 users.<\/li><\/ul>\n\n\n\n<p>Tell the doctor immediately if you notice any of the above signs.&nbsp;<\/p>\n\n\n\n<p><strong>Other\u00a0side effects\u00a0ar<\/strong><\/p>\n\n\n\n<p><strong>Common &#8211;<\/strong>&nbsp;may affect up to 1 in 10 users<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Redness<\/li><li>Increased&nbsp;blood pressure<\/li><\/ul>\n\n\n\n<p><strong>Uncommon &#8211;<\/strong>&nbsp;may affect up to 1 in 100 users.&nbsp;You may experience the following less common side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Dizziness<\/li><li>Feeling of worry<\/li><li>Nausea<\/li><li>Chest discomfort<\/li><li>Low blood sugar (symptoms: hunger and headache)<\/li><li>Back pain<\/li><li>Feeling feverish or feeling frozen<\/li><li>Increased respiratory rate<\/li><li>Pain at the injection site<\/li><li>Pounding heart (palpitations)<\/li><li>Pain in muscles or bones<\/li><li>Tremors (\u00a0tremors\u00a0)<\/li><li>Swollen skin<\/li><li>Fever<\/li><li>Increased breathing (\u00a0hyperventilation\u00a0)<\/li><li>Taste changes<\/li><li>Feeling of dizziness<\/li><li>Impaired sensation or feeling of numbness<\/li><li>Fatigue or weakness<\/li><li>Inability to get or maintain\u00a0an erection<\/li><li>Indigestion, stomach ache, or sore mouth<\/li><li>Vomiting<\/li><li>Decreased sensation or sensitivity, especially in the skin or face<\/li><li>Elevated values \u200b\u200bfor\u00a0lactate dehydrogenase\u00a0or\u00a0neutrophils\u00a0in blood samples<\/li><li>Tightening skin<\/li><\/ul>\n\n\n\n<p>This radiopharmaceutical emits low amounts of ionizing radiation, which is associated with a very low risk of cancer and gene defects (ie, genetic disorders).<\/p>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<p>If you get side effects, talk to your doctor, pharmacist, or nurse.\u00a0This also applies to any side effects not mentioned in this information.\u00a0You can also report side effects directly to the Swedish Medicines Agency,\u00a0www.lakemedelsverket.se.\u00a0By reporting side effects, you can help increase information about drug safety. <a href=\"javascript:void(0);\">Postal address<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How VIZAMYL should be stored<\/h2>\n\n\n\n<p>You do not need to store this medicine yourself.\u00a0The isotope doctor is responsible for the medicine being stored in a suitable place.\u00a0Storage of radiopharmaceuticals takes place by national regulations on radioactive materials.<\/p>\n\n\n\n<p>The following information is only intended for the isotope doctor.<\/p>\n\n\n\n<p>VIZAMYL must not be used after the expiry date which is stated on the label of the protective container after &#8220;Exp.date.&#8221;<\/p>\n\n\n\n<p>VIZAMYL should not be used if the bottle is not intact or if the solution contains particles or is discolored.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is flutemetamol (\u00a0<sup>18<\/sup>\u00a0F).\u00a01 ml of solution contains flutemetamol (\u00a0<sup>18<\/sup>\u00a0F) 400 MBq at the day and time of calibration.<\/li><li>The other ingredients are sodium chloride and anhydrous\u00a0ethanol, polysorbate 80, sodium dihydrogen phosphate dihydrate, disodium hydrogen phosphate dodecahydrate, and water for injections, see section 2.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>VIZAMYL is a clear, colorless slightly yellow solution for\u00a0injection.<\/li><li>VIZAMYL is supplied in a 10 ml or 15 ml glass\u00a0vial\u00a0stored in a container.<\/li><li>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p>GE Healthcare AS<\/p>\n\n\n\n<p>Nycoveien 1,<br>NO-0485 Oslo<\/p>\n\n\n\n<p>Norway<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>MAP Medical Technologies Oy<\/p>\n\n\n\n<p>Saukonpaadenranta 2<\/p>\n\n\n\n<p>Helsinki, FI-00180<\/p>\n\n\n\n<p>Finland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>VIZAMYL contains the active substance flutemetamol (\u00a018\u00a0F) and is used to help diagnose\u00a0Alzheimer&#8217;s disease\u00a0and other causes of memory loss.\u00a0This medicine is a radiopharmaceutical product used to make a diagnosis.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[27648,27650,27651,27652,27656,27655,27649,27647,27653,27654],"class_list":["post-30845","post","type-post","status-publish","format-standard","hentry","category-medicines","category-v","tag-flutemetamol","tag-flutemetamol-injection","tag-flutemetamol-side-effects","tag-vizamyl","tag-vizamyl-injection","tag-vizamyl-side-effects","tag-what-flutemetamol-is-used-for","tag-what-is-flutemetamol","tag-what-is-vizamyl","tag-what-vizamyl-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/30845","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=30845"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/30845\/revisions"}],"predecessor-version":[{"id":30974,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/30845\/revisions\/30974"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=30845"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=30845"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=30845"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}