{"id":28533,"date":"2022-10-29T13:09:45","date_gmt":"2022-10-29T13:09:45","guid":{"rendered":"https:\/\/zeepedia.com\/?p=28533"},"modified":"2022-11-01T10:28:12","modified_gmt":"2022-11-01T10:28:12","slug":"viatim","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/viatim\/","title":{"rendered":"ViATIM &#8211; Typhoid\u00a0polysaccharide vaccine uses, dose and side effects"},"content":{"rendered":"\n<p>suspension\u00a0and liquid for\u00a0injection,\u00a0suspension\u00a0in a pre-filled\u00a0syringe<br>hepatitis\u00a0A (inactivated,\u00a0adsorbed ) and\u00a0typhoid\u00a0polysaccharide vaccine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What ViATIM is and what it is used for<\/h2>\n\n\n\n<p>ViATIM is a vaccine.\u00a0Vaccines are used to protect you against infectious diseases.\u00a0This vaccine helps protect against both\u00a0typhoid fever\u00a0and hepatitis A\u00a0infection\u00a0in people who are 16 years of age or older.<\/p>\n\n\n\n<p>Typhoid fever\u00a0is an infectious disease that can be contracted from food and drink containing the\u00a0bacteria\u00a0(called\u00a0<em>Salmonella\u00a0enterica,\u00a0<\/em>subtype\u00a0<em>Typhi<\/em>\u00a0) that causes the disease.\u00a0It is a serious\u00a0infection\u00a0that can be fatal if not treated immediately.<\/p>\n\n\n\n<p>Hepatitis&nbsp;A&nbsp;infection&nbsp;is caused by a&nbsp;virus&nbsp;that attacks the liver.&nbsp;It can be transmitted through food or drink that contains the&nbsp;virus&nbsp;et.&nbsp;Symptoms include jaundice and general malaise.<\/p>\n\n\n\n<p>When you receive an\u00a0injection\u00a0of ViATIM, your body&#8217;s natural defenses will produce protection against\u00a0typhoid fever\u00a0and\u00a0hepatitis\u00a0A\u00a0infection.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using ViATIM<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use ViaTIM<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to active substances or any other ingredient in this vaccine (listed in section 6)<\/li><li>if you are allergic to&nbsp;neomycin&nbsp;(an&nbsp;antibiotic&nbsp;used in vaccine production and which may be present in the vaccine in small amounts)<\/li><li>if you have an illness with a fever.&nbsp;Your vaccination should be postponed until you have recovered.<\/li><\/ul>\n\n\n\n<p>To ensure that ViATIM is suitable for you, you must tell your doctor or nurse if any of the points above apply to you.\u00a0If there is something you do not understand, ask your doctor or nurse to explain.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using ViATIM.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have a reduced\u00a0immune response\u00a0due to previous or current treatment that may weaken your immune systems, such as\u00a0corticosteroids,\u00a0chemotherapy,\u00a0or radiation therapy, your doctor or nurse may want to wait until the treatment is finished.<\/li><li>If you have problems with your immune system due to human immunodeficiency\u00a0virus\u00a0(\u00a0HIV\u00a0)\u00a0infection, you can receive ViATIM, but the protective effect of the vaccine may not be as good as in those with a normal immune system.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>This vaccine does not protect against other\u00a0viruses\u00a0that can infect the liver (such as hepatitis B, hepatitis C, or hepatitis E\u00a0viruses\u00a0).\u00a0If you are already infected with the hepatitis A\u00a0virus\u00a0when you receive ViATIM, it is possible that the vaccination will not have the intended effect.<\/li><li>This vaccine does not protect you against diseases caused by Salmonella bacteria other than the particular type that causes\u00a0typhoid fever.<\/li><li>This vaccine cannot cause the\u00a0infections\u00a0it is supposed to protect against.<\/li><li>As with all vaccines, it is not certain that ViATIM will provide complete protection against hepatitis A and\u00a0typhoid fever\u00a0in everyone vaccinated.<\/li><\/ul>\n\n\n\n<p>Fainting may occur (usually in young people) after or even before the needle stick.\u00a0Therefore, tell the doctor or nurse if you or your child fainted during a previous needle stick.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other vaccines or medicines and ViATIM<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are using, have recently used, or might be using other medicines.<\/p>\n\n\n\n<p>As ViATIM does not contain any live bacteria or\u00a0viruses, it can usually be given at the same time as other vaccines, but at a different injection site (a different part of the body, eg the other arm or leg).\u00a0ViATIM must not be mixed with any other vaccines in the same\u00a0syringe.<\/p>\n\n\n\n<p>The protection obtained when ViATIM is used simultaneously with\u00a0immunoglobulins\u00a0(\u00a0antibodies\u00a0obtained from donors) has not been evaluated.\u00a0If you need an\u00a0injection\u00a0of\u00a0immunoglobulins, it can be given at the same time or within a few weeks of receiving ViATIM.\u00a0You may then not produce as many\u00a0antibodies\u00a0against the hepatitis A\u00a0virus\u00a0as you would otherwise have done, but, likely, you will still be protected against\u00a0infection.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this vaccine.<\/p>\n\n\n\n<p>Although it is not thought that ViATIM could harm an unborn baby, your doctor or nurse should decide whether you should be vaccinated now or after the baby is born.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Dizziness has been reported in some people (less than 1 in 100 but more than 1 in 1,000) after receiving ViATIM, so caution should be exercised when driving or using machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with a doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">ViATIM contains phenylalanine, ethanol, potassium, and sodium<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>ViATIM contains 10 micron of phenylalanine per 1 ml, corresponding to 0.17 micron\/kg for a 60 kg person.<br>Phenylalanine can be harmful if you have phenylketonuria (PKU), a rare, inherited disease that leads to the accumulation of high levels of phenylalanine in the body.<\/li><li>ViATIM contains 2 mg of alcohol (\u00a0ethanol\u00a0) per 1 ml\u00a0dose.\u00a0The small amount of alcohol in this medicine does not produce any noticeable effects.<\/li><li>This vaccine contains less than 1 mmol (39 mg) per\u00a0dose of\u00a0potassium\u00a0and less than 1 mmol\u00a0sodium\u00a0(23 mg) per\u00a0dose\u00a0and is almost &#8216;potassium-free&#8217; and &#8216;sodium-free&#8217;.<\/li><\/ul>\n\n\n\n<p><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use ViATIM<\/h2>\n\n\n\n<p>Vaccination should be given by health care professionals who are trained in the use of vaccines and who are equipped to deal with any unusual serious\u00a0allergic reaction\u00a0after\u00a0the injection\u00a0.<\/p>\n\n\n\n<p>Always use this medicine exactly as your doctor, pharmacist or nurse has told you.\u00a0Consult a doctor, pharmacist, or nurse if you are unsure.<\/p>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one milliliter of the mixed vaccine, for people who are 16 years of age or older.&nbsp;A single&nbsp;dose&nbsp;of the vaccine provides basic protection.<\/p>\n\n\n\n<p>This vaccine starts to protect you against hepatitis A about 14 days after you receive the first\u00a0dose.\u00a0You will need a second\u00a0dose\u00a0(booster dose) of inactivated hepatitis A vaccine to get long-term protection against hepatitis A. This booster dose will protect you against hepatitis A for more than ten years.\u00a0The booster dose must be given within 36 months, but preferably within 6 to 12 months after the first\u00a0dose.<\/p>\n\n\n\n<p>This vaccine can be given to you to provide long-term protection against hepatitis A (if you have already received a first\u00a0dose\u00a0of inactivated hepatitis A vaccine 6 to 36 months earlier and if you also need protection against\u00a0typhoid fever\u00a0).\u00a0If the first\u00a0dose of\u00a0a\u00a0hepatitis\u00a0A vaccine was given as a combined\u00a0hepatitis\u00a0A and\u00a0typhoid\u00a0vaccine, the second\u00a0dose\u00a0of a combined vaccine should usually be given about 36 months after the first\u00a0dose of\u00a0one.<\/p>\n\n\n\n<p>This vaccine starts to protect you against\u00a0typhoid fever\u00a0about 14 days after you receive\u00a0injection\u00a0one and the protection can last for about 3 years.\u00a0If after 3 years you are still at risk of getting\u00a0typhoid fever, you should make sure to get another\u00a0injection\u00a0of Vi polysaccharide vaccine against\u00a0typhoid fever.<\/p>\n\n\n\n<p>The liquids in the two chambers are mixed in the syringe just before an&nbsp;injection&nbsp;is given.&nbsp;Once mixed, the doctor or nurse will shake the syringe and check that the liquid is a cloudy, whitish&nbsp;suspension&nbsp;and that there are no abnormal particles in it.<\/p>\n\n\n\n<p><strong>Mode of administration<\/strong><\/p>\n\n\n\n<p>This vaccine is given as a slow\u00a0injection\u00a0into a muscle in the upper outer part of your arm.\u00a0Your doctor or nurse will avoid giving you an\u00a0injection\u00a0into the skin or a blood vessel.\u00a0This vaccine should not be given in the buttock.<\/p>\n\n\n\n<p>If you suffer from&nbsp;hemophilia&nbsp;(a condition where you bruise or bleed easily) or any other condition that means you shouldn&#8217;t get an&nbsp;injection&nbsp;into the muscle, you can get an&nbsp;injection&nbsp;under the skin.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you used too much ViATIM&nbsp;<\/h2>\n\n\n\n<p>In some cases, more than the recommended&nbsp;dose&nbsp;has been used.<\/p>\n\n\n\n<p>In cases where&nbsp;side effects&nbsp;were reported, they were similar to those described in section 4.<\/p>\n\n\n\n<p>If you have any further questions about the use of this vaccine, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines and vaccines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Serious allergic reactions have been reported:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe allergic reactions (\u00a0anaphylactic reaction\u00a0) with one or more of the following symptoms:<ul><li>hives\/rash<\/li><li>swelling of the face and\/or throat, difficulty breathing, blue discoloration of the tongue or lips<\/li><li>low\u00a0blood pressure, rapid heartbeat and weak\u00a0pulse, cold skin, dizziness and which can lead to the collapse<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>When these reactions do occur, they usually develop very soon after the injection is given and while the affected person is still in the clinic or doctor&#8217;s office.<\/p>\n\n\n\n<p><strong>If any of these symptoms occur after you have left the place where the\u00a0injection\u00a0was given, you must contact a doctor IMMEDIATELY<\/strong>.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Serum sickness:<ul><li>joint pain, skin rash, enlarged\u00a0lymph nodes,\u00a0and a general feeling of malaise.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>When these symptoms occur, it is usually 2-4 weeks after the vaccine is taken.&nbsp;<strong>If these symptoms occur, you must see a doctor as soon as possible.<\/strong>&nbsp;<\/p>\n\n\n\n<p><strong>Very common reactions<\/strong>&nbsp;(may affect more than 1 in 10 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>pain at the injection site, which sometimes lasts more than 3 days.\u00a0The pain may be intense in up to 1 in 10 people (common)<\/li><li>redness, swelling, and induration in the area where the vaccine was injected.\u00a0The swelling and hardening may be severe in up to 1 in 10 people (common)<\/li><li>headache<\/li><li>feeling of weakness<\/li><li>malaise<\/li><li>muscle pain.<\/li><\/ul>\n\n\n\n<p><strong>Common reactions<\/strong>&nbsp;(may affect up to 1 in 10 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>nausea<\/li><li>diarrhea<\/li><li>joint pain<\/li><li>fever (elevated temperature).<\/li><\/ul>\n\n\n\n<p><strong>Uncommon reactions<\/strong>&nbsp;(may affect up to 1 in 100 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>skin itching<\/li><li>rash<\/li><li>dizziness<\/li><\/ul>\n\n\n\n<p><strong>Very rare reactions<\/strong>&nbsp;(may affect up to 1 in 10,000 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>a lump forms at the injection site<\/li><\/ul>\n\n\n\n<p><strong>Reactions with no known frequency<\/strong>\u00a0(frequency cannot be calculated from available data).<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>worsening of&nbsp;asthma&nbsp;in people who already have&nbsp;asthma<\/li><li>fainting as a result of needle stick<\/li><li>a feeling of numbness or tingling in the skin<\/li><li>rash that is sometimes lumpy and itchy<\/li><li>vomiting, pain in the stomach<\/li><li>changes in blood tests that measure how the liver is working<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How ViATIM should be stored<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the outer carton and the syringe label after EXP.<\/p>\n\n\n\n<p>The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in a refrigerator (2 \u00b0C-8 \u00b0C).&nbsp;Do not freeze.&nbsp;Store the vaccine in the outer carton.&nbsp;Light sensitive.<\/p>\n\n\n\n<p>The vaccine should not be used if there are abnormal particles in it.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>The active substances are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hepatitis\u00a0A\u00a0virus, GBM strain (inactivated)\u00a0<sup>1.2<\/sup>\u00a0\u2026.160 units<\/li><\/ul>\n\n\n\n<ol class=\"wp-block-list\"><li><sup><\/sup>Cultured on human diploid (MRC-5) cells<\/li><li><sup><\/sup>Adsorbed&nbsp;on aluminum hydroxide, hydrated (0.3 mg Al)Aluminum hydroxide is included in the vaccine as an adsorbent.&nbsp;Adsorbents are substances included in some vaccines to accelerate, enhance and\/or prolong the protective effects of the vaccine<\/li><\/ol>\n\n\n\n<ul class=\"wp-block-list\"><li>Vi capsular polysaccharide of&nbsp;<em>Salmonella&nbsp;typhi<\/em>&nbsp;(Ty 2 strain) 25 micrograms<\/li><\/ul>\n\n\n\n<p>The other ingredients are sodium chloride, disodium phosphate dihydrate, sodium dihydrogen phosphate dihydrate, 2-phenoxyethanol,\u00a0ethanol\u00a0anhydrous, formaldehyde and Medium 199, Hanks, without phenol red (a\u00a0mixture\u00a0of\u00a0amino acids\u00a0including phenylalanine (see section 2), mineral salts (including\u00a0potassium\u00a0),\u00a0vitamins\u00a0and other substances ) supplemented with polysorbate 80, and water for injections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>The vaccine comes in a pre-filled&nbsp;syringe&nbsp;with two chambers (0.5 ml of inactivated hepatitis A&nbsp;virus&nbsp;in one chamber and 0.5 ml of&nbsp;typhoid&nbsp;polysaccharide vaccine in the other chamber).<\/p>\n\n\n\n<p>Pack size: 1 or 10 syringes with or without a needle.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<p>The inactivated&nbsp;Hepatitis&nbsp;A vaccine is a cloudy, white&nbsp;suspension and the&nbsp;typhoid&nbsp;polysaccharide vaccine is&nbsp;a clear, colorless liquid.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Sanofi Pasteur Europe<\/p>\n\n\n\n<p>14 Espace Henry Vall\u00e9e<\/p>\n\n\n\n<p>69007 Lyon<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Sanofi PasteurCampus M\u00e9rieux1541 avenue Marcel M\u00e9rieux,69280 Marcy l&#8217;EtoileFrance<\/td><td>or<\/td><td>Sanofi PasteurParc Industriel D&#8217;Incarville27100 Val de Reuil,France<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Local representative:<\/strong><\/p>\n\n\n\n<p>Sanofi AB<\/p>\n\n\n\n<p>Box 30052<\/p>\n\n\n\n<p>104 25 Stockholm<\/p>\n\n\n\n<p>Phone: +46 8-634 50 00<\/p>\n\n\n\n<p><strong>This medicine\u00a0is\u00a0approved within the European Economic Area\u00a0under the\u00a0names\u00a0:<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Member State<\/strong><\/td><td><strong>Name<\/strong><\/td><\/tr><tr><td>Denmark, Finland, Germany, Greece, Iceland, Ireland, Luxembourg, Norway, Portugal, Sweden, Netherlands, United Kingdom, Austria<\/td><td>ViaATIM<\/td><\/tr><tr><td>Belgium<\/td><td>VACCIN COMBINE TYPHOIDIQUE POLYOSIDIQUE VI PURIFIE ET \u200b\u200bHEPATITE A<\/td><\/tr><tr><td>France, Spain<\/td><td>TYAVAX<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>ViATIM is a vaccine.\u00a0Vaccines are used to protect you against infectious diseases.\u00a0This vaccine helps protect against both\u00a0typhoid fever\u00a0and hepatitis A\u00a0infection\u00a0in people who are 16 years of age or older.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[27412,27418,27413,27414,27410,27417,27409,27415,27411,27416],"class_list":["post-28533","post","type-post","status-publish","format-standard","hentry","category-medicines","category-v","tag-benefits-of-typhoid-polysaccharide-vaccine","tag-benefits-of-viatim","tag-typhoid-polysaccharide-vaccine","tag-typhoid-polysaccharide-vaccine-side-effects","tag-viatim","tag-viatim-side-effects","tag-what-is-typhoid-polysaccharide-vaccine","tag-what-is-viatim","tag-what-typhoid-polysaccharide-vaccine-is-used-for","tag-what-viatim-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/28533","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=28533"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/28533\/revisions"}],"predecessor-version":[{"id":28572,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/28533\/revisions\/28572"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=28533"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=28533"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=28533"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}