{"id":28481,"date":"2022-10-28T13:31:32","date_gmt":"2022-10-28T13:31:32","guid":{"rendered":"https:\/\/zeepedia.com\/?p=28481"},"modified":"2022-10-29T10:05:13","modified_gmt":"2022-10-29T10:05:13","slug":"verquvo","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/verquvo\/","title":{"rendered":"Verquvo &#8211; Vericiguat uses, dose and side effects"},"content":{"rendered":"\n<p>Verquvo 2.5 mg film-coated tablets, Verquvo 5 mg film-coated tablets, Verquvo 10 mg film-coated tablets<br>vericiguat<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Verquvo is and what it is used for<\/h2>\n\n\n\n<p>Verquvo contains the active substance vericiguat, which is a type of heart medicine called a soluble\u00a0guanylate cyclase\u00a0stimulator.<\/p>\n\n\n\n<p>Verquvo is used to treat adults with long-term\u00a0heart failure\u00a0who have recently had increased symptoms of\u00a0heart failure.\u00a0You may therefore have been admitted to the hospital and\/or given a medicine (diuretic\/diuretic) administered into a vein (\u00a0intravenously\u00a0) to make you urinate more than usual.<\/p>\n\n\n\n<p>Heart failure\u00a0is when the heart is weak and cannot pump enough blood around the body.\u00a0Some common symptoms of\u00a0heart failure\u00a0are shortness of breath, fatigue, or swelling due to fluid retention.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Verquvo<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Verquvo<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are\u00a0<strong>allergic<\/strong>\u00a0to vericiguat or any of the other ingredients of this medicine (listed in section 6),<\/li><li>if you are taking any medicine containing another\u00a0<strong>stimulator of soluble\u00a0guanylate cyclase<\/strong>, eg\u00a0riociguat used to treat high\u00a0blood pressure\u00a0in the lungs.<\/li><\/ul>\n\n\n\n<p>If any of the above apply to you, do not take this medicine without\u00a0<strong>first talking to your doctor<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Verquvo, if you have<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>low\u00a0blood pressure<\/strong>\u00a0with symptoms such as dizziness or feeling unsteady<\/li><li><strong>severe kidney problems<\/strong>\u00a0or\u00a0<strong>dialysis treatment<\/strong><\/li><li><strong>severe liver problems<\/strong>.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children and adolescents under the age of 18, as it has not yet been studied in this age group.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Verquvo<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, especially those which<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>belongs to the group of soluble\u00a0guanylate cyclase\u00a0stimulators (e.g. riociguat).\u00a0Do not take Verquvo while taking these medicines.\u00a0See \u201cDo not take Verquvo\u201d.<\/li><li>treat high\u00a0blood pressure\u00a0in the lungs or medicines to get or keep an\u00a0erection\u00a0called PDE5 inhibitors (eg sildenafil, tadalafil, vardenafil).\u00a0The use of these medicines is not recommended while taking Verquvo.<\/li><li>treat heart disease with chest pain and which are called nitrates (eg\u00a0isosorbide mononitrate\u00a0).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>Vericiguat should not be used during pregnancy, as it is not known whether it will harm the unborn baby.&nbsp;If you can get pregnant, talk to your doctor about reliable birth control.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>It is not known whether Verquvo passes into breast milk and could harm your baby.&nbsp;The doctor will decide together with you whether you should stop breastfeeding or whether treatment with Verquvo should be ended.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>If you feel dizzy during treatment with this medicine, you should not drive, cycle or use any machinery.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Verquvo contains lactose and sodium<\/h2>\n\n\n\n<p>This medicine contains\u00a0lactose.\u00a0If you have an intolerance to certain sugars, you should consult your doctor before taking this medicine.<\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg) of\u00a0sodium\u00a0per\u00a0dose, i.e. it is almost &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Verquvo<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The recommended\u00a0<strong>starting dose is 1 tablet of 2.5 mg<\/strong>\u00a0once daily.\u00a0The doctor will then adjust the\u00a0dose\u00a0depending on how well you tolerate the treatment.\u00a0Usually, the doctor increases the\u00a0dose\u00a0after about 2 weeks to 1 tablet of 5 mg once daily and after another 2 weeks to the\u00a0<strong>highest target dose of 1 tablet of 10 mg<\/strong>\u00a0once daily.<\/p>\n\n\n\n<p>If you develop&nbsp;<strong>low&nbsp;blood pressure<\/strong>&nbsp;during treatment with Verquvo, you may feel dizzy and unsteady.&nbsp;The doctor can then temporarily lower the Verquvo&nbsp;dose&nbsp;or stop the treatment with Verquvo.<\/p>\n\n\n\n<p>Take one tablet at the same time each day with food.&nbsp;If you cannot swallow the tablet, you can crush Verquvo and mix it with water.&nbsp;Take this&nbsp;mixture&nbsp;immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Verquvo<\/h2>\n\n\n\n<p>Contact your doctor immediately if you have taken too much Verquvo and you experience any of the\u00a0side effects\u00a0listed in section 4. The most likely effect is a drop in\u00a0blood pressure, which may make you feel dizzy and unsteady.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Verquvo<\/h2>\n\n\n\n<p>Take the forgotten tablet as soon as you remember on the same day as the\u00a0missed dose.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed tablet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Verquvo<\/h2>\n\n\n\n<p>Do not stop taking this medicine without first talking to your doctor.&nbsp;If you stop taking this medicine, your condition may worsen.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Possible&nbsp;side effects&nbsp;are:<\/strong><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 in 10 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>low&nbsp;blood pressure&nbsp;(&nbsp;hypotension&nbsp;)<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the low number of\u00a0red blood cells\u00a0(anemia), which can cause pale skin, weakness, or shortness of breath<\/li><li>dizziness<\/li><li>headache<\/li><li>nausea and vomiting<\/li><li>indigestion (\u00a0dyspepsia\u00a0)<\/li><li>heartburn (\u00a0gastroesophageal reflux disease\u00a0)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Verquvo<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton and each blister or can after &#8220;EXP&#8221;.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>&#8211; The active substance is vericiguat.\u00a0Each film-coated tablet contains 2.5 mg, 5 mg, or 10 mg of vericiguat.<\/p>\n\n\n\n<p>&#8211; Other ingredients are:<\/p>\n\n\n\n<p><em>Tablet core:<\/em>\u00a0Microcrystalline cellulose, croscarmellose sodium, hypromellose 2910,\u00a0lactose monohydrate, magnesium stearate, sodium lauryl sulfate (see section 2 &#8220;Verquvo contains\u00a0lactose\u00a0and sodium&#8221;).<\/p>\n\n\n\n<p><em>Film coating:<\/em>&nbsp;Hypromellose 2910, talc, titanium dioxide (E 171), red iron oxide (E 172) (only Verquvo 5 mg), yellow iron oxide (E 172) (only Verquvo 10 mg).<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Verquvo 2.5 mg film-coated tablets (tablets) are round, biconvex, and white with a diameter of 7 mm, marked with \u201c2.5\u201d on one side and \u201cVC\u201d on the other side.<\/p>\n\n\n\n<p>Verquvo 5 mg film-coated tablets (tablets) are round, biconvex, and brown-red with a diameter of 7 mm, marked with \u201c5\u201d on one side and \u201cVC\u201d on the other side.<\/p>\n\n\n\n<p>Verquvo 10 mg film-coated tablets (tablets) are round, biconvex, and yellow-orange colored with a diameter of 9 mm, marked with \u201c10\u201d on one side and \u201cVC\u201d on the other side.<\/p>\n\n\n\n<p>Verquvo exists<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>in blisters in cartons of 14, 28, or 98 film-coated tablets<\/li><li>in perforated single-dose blisters in cartons of 10 x 1 or 100 x 1 film-coated tablets<\/li><li>in jars of 100 film-coated tablets.<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p>Bayer AG<\/p>\n\n\n\n<p>51368 Leverkusen<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Bayer AG<\/p>\n\n\n\n<p>Kaiser Wilhelm Allee<\/p>\n\n\n\n<p>51368 Leverkusen<\/p>\n\n\n\n<p>Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Verquvo contains the active substance vericiguat, which is a type of heart medicine called a soluble\u00a0guanylate cyclase\u00a0stimulator .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[27375,27376,27377,27379,27382,27383,27374,27381,27378,27380],"class_list":["post-28481","post","type-post","status-publish","format-standard","hentry","category-medicines","category-v","tag-vericiguat","tag-vericiguat-side-effects","tag-vericiguat-tablet","tag-verquvo","tag-verquvo-side-effects","tag-verquvo-tablet","tag-what-is-vericiguat","tag-what-is-verquvo","tag-what-vericiguat-is-used-for","tag-what-verquvo-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/28481","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=28481"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/28481\/revisions"}],"predecessor-version":[{"id":28523,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/28481\/revisions\/28523"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=28481"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=28481"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=28481"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}