{"id":27311,"date":"2022-10-19T12:24:24","date_gmt":"2022-10-19T12:24:24","guid":{"rendered":"https:\/\/zeepedia.com\/?p=27311"},"modified":"2022-10-20T07:04:17","modified_gmt":"2022-10-20T07:04:17","slug":"vedrop","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/vedrop\/","title":{"rendered":"Vedrop &#8211; Tocofersolan uses, dose and side effects"},"content":{"rendered":"\n<p>50 mg\/ml&nbsp;oral&nbsp;solution<br>Tocofersolan<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Vedrop is and what it is used for<\/h2>\n\n\n\n<p>Vedrop contains\u00a0vitamin E\u00a0(in the form of tocopherol).\u00a0It is used to treat vitamin E deficiency due to malabsorption (where nutrients in the stomach are not easily absorbed when food is digested) in patients from birth (full-term newborns) to age 18 with\u00a0chronic\u00a0cholestasis (an inherited or congenital disease in which bile cannot be transported from the liver to the intestine).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Vedrop<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Vedrop<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to\u00a0vitamin E\u00a0(d-alpha-tocopherol) or any of the other ingredients of this medicine (listed in section 6).<\/li><li>Vedrop must not be used in newborn premature babies.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking Vedrop if you have:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>kidney problems or suffer from dehydration.\u00a0Vedrop should only be used with caution and your kidney function should be closely monitored because polyethylene glycol, part of the active substance tocopherol, can damage your kidneys.<\/li><li>problems with the liver.\u00a0Vedrop should only be used with caution and liver function should be closely monitored.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Vedrop<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including those obtained without a prescription.<\/p>\n\n\n\n<p>Tell your doctor and pharmacist if you are taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>certain medicines for thinning the blood (oral\u00a0anticoagulants\u00a0such as\u00a0warfarin\u00a0).\u00a0A doctor will then take regular blood tests and may adjust the\u00a0dose\u00a0to avoid a higher risk of bleeding.<\/li><li>fat-soluble\u00a0vitamins\u00a0(eg A, D, E, or K) or significantly fat-soluble drugs (eg corticoids, cyclosporine, tacrolimus, or\u00a0antihistamines\u00a0).\u00a0As Vedrop can increase absorption during digestion, the doctor will monitor the treatment effect and adjust the\u00a0doses\u00a0if necessary.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>No clinical data are available on exposure to this drug during pregnancy.&nbsp;Inform the doctor if you are pregnant so that he\/she can decide if the medicine can be used.<\/p>\n\n\n\n<p>There is no information on whether this drug is excreted in breast milk.\u00a0Inform the doctor if you want to breastfeed.\u00a0He\/she will help you decide what is best for you and your child.<\/p>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Vedrop is unlikely to affect your ability to drive and use machines.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Vedrop contains sodium methyl parahydroxybenzoate (E219) and sodium ethyl parahydroxybenzoate (E215) &nbsp;<\/h2>\n\n\n\n<p>which can cause an&nbsp;allergic reaction&nbsp;(possibly delayed).<\/p>\n\n\n\n<p>Vedrop contains 0.18 mmol (4.1 mg)&nbsp;sodium&nbsp;per ml.&nbsp;Talk to your doctor if you are on a sodium-restricted diet.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Vedrop<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The usual&nbsp;dose&nbsp;is 0.34 ml\/kg\/day.<\/p>\n\n\n\n<p>The doctor will prescribe a&nbsp;dose&nbsp;of one in ml.<\/p>\n\n\n\n<p>The dose&nbsp;will be adjusted by the doctor according to the level of vitamin E in your blood.<\/p>\n\n\n\n<p><strong>Mode of administration<\/strong><\/p>\n\n\n\n<p>Swallow the solution with or without water.&nbsp;It should only be used with the&nbsp;oral&nbsp;syringe provided in the package.<\/p>\n\n\n\n<p>You can take Vedrop before or after a meal, with or without water.<\/p>\n\n\n\n<p>Measurement of the dose:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>1- Open the bottle2- Place the syringe, which is included in the package, in the bottle<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20071025000010#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>3- Fill the syringe with the liquid by pulling the plunger up to the graduation corresponding to the amount in milliliters (ml) prescribed by the doctor.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20071025000010#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>4- Take the syringe out of the bottle.5- Empty the contents of the syringe by depressing the plunger either: directly in the mouth or a glass of water and then drinking the entire contents.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20071025000010#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>6- Close the bottle.7- Wash the syringe with water.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20071025000010#\" rel=\"noopener\"><\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Vedrop<\/h2>\n\n\n\n<p>If you take large\u00a0doses\u00a0of\u00a0vitamin E, you may experience temporary diarrhea and stomach pain.\u00a0Talk to your doctor or pharmacist if symptoms persist for more than two days.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Vedrop<\/h2>\n\n\n\n<p>Skip the missed\u00a0dose\u00a0and return to the normal\u00a0dosage.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Vedrop<\/h2>\n\n\n\n<p>Do not stop treatment without consulting a doctor as vitamin E deficiency may return and affect your health.&nbsp;Consult a doctor or pharmacist before stopping.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been reported:<\/p>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(<\/strong>&nbsp;may affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Diarrhea<\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(<\/strong>&nbsp;may affect up to 1 in 100 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Asthenia&nbsp;(feeling of weakness)<\/li><li>Headache<\/li><li>Hair loss<\/li><li>Itching<\/li><li>Rash (skin reactions)<\/li><li>Abnormal level of sodium in the blood<\/li><li>Abnormal level of potassium in the blood<\/li><li>Increase in&nbsp;transaminases&nbsp;(liver enzymes)<\/li><\/ul>\n\n\n\n<p><strong>Frequency not known<\/strong>&nbsp;(cannot be estimated from available data)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Stomach ache<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How Vedrop should be stored<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Use before the expiry date which is stated on the carton and bottle after EXP.\u00a0The expiration date is the last day of the specified month.<\/li><li>This medicine does not need special storage instructions.<\/li><li>Discard the bottle one month after the first opening, even if there is a solution left in the bottle.<\/li><\/ul>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is tocopherol.\u00a0Each ml of solution contains 50 mg of d-alpha-tocopherol in the form of tocopherol, which corresponds to 74.5 IU of tocopherol.<\/li><li>The other ingredients are: potassium sorbate, sodium methyl parahydroxybenzoate (E219) and sodium ethyl parahydroxybenzoate (E215) (see the end of section 2 for further information on these 2 ingredients),\u00a0glycerol, disodium phosphate dodecahydrate, concentrated\u00a0hydrochloric acid\u00a0and purified water.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Vedrop is a slightly\u00a0viscous\u00a0and pale yellow\u00a0oral\u00a0solution in a brown glass bottle that is closed with a child-resistant screw cap.\u00a0The bottles contain 10 ml, 20 ml, or 60 ml\u00a0of oral\u00a0solution.\u00a0Each carton contains a vial and a\u00a0syringe\u00a0for\u00a0oral\u00a0use (a 1 mL\u00a0syringe\u00a0with a 10 mL or 20 mL vial, and a 2 mL\u00a0syringe\u00a0with a 60 mL vial).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Recordati Rare Diseases<\/p>\n\n\n\n<p>Building &#8220;Le Wilson&#8221;<\/p>\n\n\n\n<p>70, avenue du General de Gaulle<\/p>\n\n\n\n<p>F-92800 Puteaux<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Recordati Rare Diseases<\/p>\n\n\n\n<p>Building &#8220;Le Wilson&#8221;<\/p>\n\n\n\n<p>70, avenue du G\u00e9n\u00e9ral de Gaulle<\/p>\n\n\n\n<p>F-92800 Puteaux<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Recordati Rare Diseases<\/p>\n\n\n\n<p>Eco River Park<\/p>\n\n\n\n<p>30, rue des Peupliers<\/p>\n\n\n\n<p>F-92000 Nanterre<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p>Contact the representative of the Marketing Authorization Holder if you would like to know more about this medicine:<\/p>\n\n\n\n<p><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20071025000010#\" rel=\"noopener\">View larger<\/a><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgique\/Belgi\u00eb\/Belgien<\/strong>RecordatiT\u00e9l\/Tel: +32 2 46101 36<\/td><td><strong>Lithuania<\/strong>Recordati AB.Phone: + 46 8 545 80 230Sweden<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Recordati Rare DiseasesTel.: +33 (0)1 47 73 64 58France<\/td><td><strong>Luxembourg\/Luxembourg<\/strong>RecordatiT\u00e9l\/Tel: +32 2 46101 36Belgique\/Belgium<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Recordati Rare DiseasesPhone: +33 (0)1 47 73 64 58Francie<\/td><td><strong>Magyarorsz\u00e1g<\/strong>Recordati Rare DiseasesPhone: +33 (0)1 47 73 64 58France<\/td><\/tr><tr><td><strong>Denmark<\/strong>Recordati AB.Phone: +46 8 545 80 230Sweden<\/td><td><strong>Malta<\/strong>Recordati Rare DiseasesPhone: +33 1 47 73 64 58Franza<\/td><\/tr><tr><td><strong>Deutschland<\/strong>Recordati Rare Diseases Germany GmbHPhone: +49 731 140 554 0<\/td><td><strong>The Netherlands<\/strong>RecordatiPhone: +32 2 46101 36Belgium<\/td><\/tr><tr><td><strong>Estonia<\/strong>Recordati AB.Phone: + 46 8 545 80 230Roots<\/td><td><strong>Norway<\/strong>Recordati AB.Phone: +46 8 545 80 230Sweden<\/td><\/tr><tr><td><strong>Greece<\/strong>Recordati Rare DiseasesPhone: +33 1 47 73 64 58France<\/td><td><strong>Austria<\/strong>Recordati Rare Diseases Germany GmbH&nbsp;Phone: +49 731 140 554 0Deutschland<\/td><\/tr><tr><td><strong>Spain<\/strong>Recordati Rare Diseases SpainPhone: + 34 91 659 28 90<\/td><td><strong>Polish<\/strong>Recordati Rare Diseases&nbsp;Phone: +33 (0)1 47 73 64 58France<\/td><\/tr><tr><td><strong>France<\/strong>Recordati Rare Diseases&nbsp;Tel: +33 (0)1 47 73 64 58<\/td><td><strong>Portugal<\/strong>Jaba Recordati SA&nbsp;Phone: +351 21 432 95 00<\/td><\/tr><tr><td><strong>Hrvatska<\/strong>Recordati Rare Diseases&nbsp;Tel: +33 (0)1 47 73 64 58France<\/td><td><strong>Romania<\/strong>Recordati Rare Diseases&nbsp;Phone: +33 (0)1 47 73 64 58France<\/td><\/tr><tr><td><strong>Ireland<\/strong>Recordati Rare DiseasesPhone: +33 (0)1 47 73 64 58France<\/td><td><strong>Slovenija<\/strong>Recordati Rare DiseasesPhone: +33 (0)1 47 73 64 58France<\/td><\/tr><tr><td><strong>Iceland<\/strong>Recordati AB.Simi: +46 8 545 80 230Sweden<\/td><td><strong>Slovenian Republic<\/strong>Recordati Rare DiseasesPhone: +33 (0)1 47 73 64 58France<\/td><\/tr><tr><td><strong>Italy<\/strong>Recordati Rare Diseases Italy SrlPhone: +39 02 487 87 173<\/td><td><strong>Finland\/Finland<\/strong>Recordati AB.Tel: +46 8 545 80 230Sweden<\/td><\/tr><tr><td><strong>Cyprus<\/strong>Recordati Rare DiseasesPhone: +33 1 47 73 64 58France<\/td><td><strong>Sweden<\/strong>Recordati AB.Phone: +46 8 545 80 230<\/td><\/tr><tr><td><strong>Latvia<\/strong>Recordati AB.Phone: + 46 8 545 80 230Sweden<\/td><td><strong>United Kingdom<\/strong>Recordati Rare Diseases UK Ltd.Phone: +44 (0)1491 414333<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Vedrop contains\u00a0vitamin E\u00a0(in the form of tocofersol).\u00a0It is used to treat vitamin E deficiency due to malabsorption (where nutrients in the stomach are not easily absorbed when food is digested) in patients from birth (full-term newborns) to age 18 with\u00a0chronic\u00a0cholestasis (an inherited or congenital disease in which bile cannot be transported from the liver to the intestine).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[27100,27106,27098,27099,27101,27105,27097,27104,27103,27102],"class_list":["post-27311","post","type-post","status-publish","format-standard","hentry","category-medicines","category-v","tag-benefits-of-tocofersolan","tag-benefits-of-vedrop","tag-tocofersolan","tag-tocofersolan-side-effects","tag-vedrop","tag-vedrop-side-effects","tag-what-is-tocofersolan","tag-what-is-vedrop","tag-what-tocofersolan-is-used-for","tag-what-vedrop-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/27311","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=27311"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/27311\/revisions"}],"predecessor-version":[{"id":27360,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/27311\/revisions\/27360"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=27311"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=27311"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=27311"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}