{"id":27288,"date":"2022-10-19T12:12:06","date_gmt":"2022-10-19T12:12:06","guid":{"rendered":"https:\/\/zeepedia.com\/?p=27288"},"modified":"2022-10-20T07:04:54","modified_gmt":"2022-10-20T07:04:54","slug":"vaxneuvance","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/vaxneuvance\/","title":{"rendered":"Vaxneuvance &#8211; Pneumococcal polysaccharide vaccine uses, dose and side effects"},"content":{"rendered":"\n<p>solution for injection,\u00a0suspension\u00a0in a pre-filled\u00a0syringe<br>conjugated pneumococcal polysaccharide vaccine (15-valent,\u00a0adsorbed\u00a0)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Vaxneuvance is and what it is used for<\/h2>\n\n\n\n<p>Vaxneuvance is a pneumococcal vaccine given to adults from the age of 18 to protect against diseases caused by 15 types of the bacterium\u00a0<em>Streptococcus pneumoniae<\/em>, also called &#8220;pneumococcus&#8221;.<\/p>\n\n\n\n<p>These diseases include\u00a0lung inflammation\u00a0(\u00a0pneumonia\u00a0),\u00a0inflammation\u00a0of the membranes around the brain and spinal cord (meningitis\/\u00a0meningitis\u00a0), and serious\u00a0infection\u00a0in the blood (blood poisoning\/sepsis).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before receiving Vaxneuvance<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">You should not receive Vaxneuvance:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to the active substances or any other ingredient in this vaccine (listed in section 6), or to any vaccine containing diphtheria toxoid.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using Vaxneuvance if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>your immune system is weak (which means that the body is less able to fight\u00a0infection\u00a0) or if you are taking certain drugs that can weaken the immune system (eg immunosuppressive drugs or\u00a0steroids\u00a0).<\/li><li>you have a high fever or a severe\u00a0infection.\u00a0In such cases, it may be necessary to postpone the vaccination until you have recovered.\u00a0However, a low fever or a mild\u00a0infection\u00a0(e.g. a cold) is no reason to postpone the vaccination.<\/li><li>you have bleeding problems, bruise easily or take medicines to prevent blood clots.<\/li><\/ul>\n\n\n\n<p>As with other vaccines, it is not certain that everyone vaccinated with Vaxneuvance will receive full protection.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>It has not been determined whether Vaxneuvance can be used in children and adolescents under the age of 18.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines\/vaccines and Vaxneuvance<\/h2>\n\n\n\n<p>Vaxneuvance can be given at the same time as the (inactivated) influenza vaccine.<\/p>\n\n\n\n<p>Tell your doctor, pharmacist, or nurse if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you are taking, have recently taken, or maybe taking prescription medicines (eg immunosuppressive medicines or\u00a0steroids, which can weaken the immune system), or any over-the-counter medicines.<\/li><li>you have recently received or plan to receive any other vaccine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor, pharmacist, or nurse for advice before using this vaccine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Vaxneuvance has no or negligible effect on the ability to drive and use machines.&nbsp;However, some of the&nbsp;side effects&nbsp;(see section 4 &#8220;Possible side effects&#8221;) may temporarily affect the ability to drive vehicles and use machines.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Vaxneuvance contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg) of\u00a0sodium\u00a0per\u00a0dose, i.e.\u00a0is almost &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to get Vaxneuvance<\/h2>\n\n\n\n<p>An&nbsp;injection&nbsp;of Vaxneuvance is given by a doctor or nurse into a muscle (preferably in the upper arm).<\/p>\n\n\n\n<p>Tell the doctor, pharmacist, or nurse if you have been vaccinated against\u00a0pneumococci\u00a0before.<\/p>\n\n\n\n<p>Special patient groups<\/p>\n\n\n\n<p>An&nbsp;injection&nbsp;of Vaxneuvance may be given to people who have one or more underlying medical conditions that increase the risk of pneumococcal disease (eg, people living with&nbsp;HIV&nbsp;[human immunodeficiency virus]).<\/p>\n\n\n\n<p>If you have any further questions about this vaccine, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all vaccines, Vaxneuvance can cause\u00a0side effects, but not all users need to get them.<\/p>\n\n\n\n<p>Seek medical attention immediately if you experience symptoms of an\u00a0allergic reaction, such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>wheezing or difficulty breathing<\/li><li>swelling of the face, lips, or tongue<\/li><li>hives\/rash<\/li><li>rash<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;may occur after using Vaxneuvance:<\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 in 10 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>pain, swelling, or\u00a0redness\u00a0at the injection site<\/li><li>fatigue<\/li><li>muscle pain<\/li><li>headache<\/li><li>joint pain (in users 18 to 49 years old)<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>joint pain (in users 50 years and older)<\/li><li>nausea (in users 18 to 49 years old)<\/li><li>fever (in users 18 to 49 years old)<\/li><li>itching&nbsp;at the injection site<\/li><li>dizziness (in users 18 to 49 years old)<\/li><li>chills (in users 18 to 49 years old)<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fever (in users 50 years and older)<\/li><li>the feeling of warmth at the injection site<\/li><li>bruising at the injection site<\/li><li>dizziness (in users 50 years and older)<\/li><li>nausea (in users 50 years and older)<\/li><li>vomiting<\/li><li>chills (in users 50 years and older)<\/li><li>rash<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>allergic reactions such as\u00a0hives, swollen tongue,\u00a0redness,\u00a0and swelling\/tightness in the throat.<\/li><\/ul>\n\n\n\n<p>These&nbsp;side effects&nbsp;are generally mild and short-lived.<\/p>\n\n\n\n<p>Tell your healthcare professional if you get any of these\u00a0side effects, or any other unusual symptoms, after receiving this vaccine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Vaxneuvance<\/h2>\n\n\n\n<p>Keep this vaccine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton and syringe label after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in a refrigerator (2 \u00b0C-8 \u00b0C).&nbsp;Do not freeze.<\/p>\n\n\n\n<p>Store the pre-filled syringe in the outer carton.&nbsp;Light sensitive.<\/p>\n\n\n\n<p>Vaxneuvance should be administered as soon as possible after removal from the refrigerator.<\/p>\n\n\n\n<p>When temporarily storing Vaxneuvance outside the refrigerator, the vaccine is stable (stable) at temperatures up to 25 \u00b0C for 48 hours.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>The active substances are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>bacterial polysaccharides from&nbsp;pneumococcal&nbsp;types 1, 3, 4, 5, 6A, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F and 33F (2.0 micrograms of each type)<\/li><li>bacterial polysaccharides from&nbsp;pneumococcus&nbsp;type 6B (4.0 micrograms).<\/li><\/ul>\n\n\n\n<p>Each bacterial polysaccharide (a type of sugar) is linked to a&nbsp;carrier protein&nbsp;(CRM&nbsp;<sub>197<\/sub>&nbsp;).&nbsp;The bacterial polysaccharides and&nbsp;carrier proteins&nbsp;are not living and do not cause disease.<\/p>\n\n\n\n<p>One\u00a0dose\u00a0(0.5 ml) contains approximately 30 micrograms of\u00a0carrier protein\u00a0adsorbed on aluminum phosphate (125 micrograms aluminum [Al\u00a0<sup>3+<\/sup>\u00a0]).\u00a0Aluminum phosphate is included in the vaccine as an\u00a0adjuvant.\u00a0Adjuvants\u00a0are added to enhance the immune system&#8217;s response to vaccines.<\/p>\n\n\n\n<p>Other ingredients are sodium chloride (NaCl), L-histidine, polysorbate 20, and water for injections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Vaxneuvance is an opalescent\u00a0suspension\u00a0for injection,\u00a0supplied in a pre-filled disposable syringe (0.5 ml).\u00a0Vaxneuvance is available in pack sizes of 1 or 10 pre-filled syringes, either without needles, with 1 separate needle per pre-filled\u00a0syringe,\u00a0or with 2 separate needles per pre-filled\u00a0syringe.<\/p>\n\n\n\n<p>Vaxneuvance is also available in multipacks consisting of 5 cartons each containing 10 pre-filled syringes without needles.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p>Merck Sharp &amp; Dohme BV<\/p>\n\n\n\n<p>Waarderweg 39<\/p>\n\n\n\n<p>2031 BN Haarlem<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p>Contact the representative of the Marketing Authorization Holder if you would like to know more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgi\u00eb\/Belgique\/Belgien<\/strong>MSD BelgiumPhone: +32 (0) 27766211dpoc_belux@merck.com<\/td><td><strong>Lithuania<\/strong>UAB Merck Sharp &amp; DohmeTel.: +370.5.2780.247msd_lietuva@merck.com<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>\u041c\u0435\u0440\u043a \u0428\u0430\u0440\u043f \u0438 \u0414\u043e\u043c \u0411\u0443\u043b\u0433\u0430\u0440\u0438\u044f \u0415\u041e\u041e\u0414tel.: + 359 2 819 3737info-msdbg@merck.com<\/td><td><strong>Luxembourg\/Luxembourg<\/strong>MSD BelgiumPhone: +32 (0) 27766211dpoc_belux@merck.com<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Merck Sharp &amp; Dohme s.r.oTel.: +420 233 010 111dpoc_czechslovak@merck.com<\/td><td><strong>Magyarorsz\u00e1g<\/strong>MSD Pharma Hungary Kft.Phone: + 36.1.888.5300hungary_msd@merck.com<\/td><\/tr><tr><td><strong>Denmark<\/strong>MSD Danmark ApSPhone: + 45 4482 4000dkmail@merck.com<\/td><td><strong>Malta<\/strong>Merck Sharp &amp; Dohme Cyprus Limited.Phone: 8007 4433 (+356 99917558)malta_info@merck.com<\/td><\/tr><tr><td><strong>Deutschland<\/strong>MSD Sharp &amp; Dohme GmbHPhone: 0800 673 673 673 (+49 (0) 89 4561 0)e-mail@msd.de<\/td><td><strong>The Netherlands<\/strong>Merck Sharp &amp; Dohme BVPhone: 0800 9999000 (+31 23 5153153)medicalinfo.nl@merck.com<\/td><\/tr><tr><td><strong>Estonia<\/strong>Merck Sharp &amp; Dohme O\u00dcTel.: +372 6144 200msdeesti@merck.com<\/td><td><strong>Norway<\/strong>MSD (Norway) iPhone: +47 32 20 73 00msdnorge@msd.no<\/td><\/tr><tr><td><strong>Greece<\/strong>MSD \u0391.\u03a6.\u0392.\u0395.\u0395.Tel: +30 210 98 97 300dpoc_greece@merck.com<\/td><td><strong>Austria<\/strong>Merck Sharp &amp; Dohme Ges.mbHPhone: +43 (0) 1 26 044dpoc_austria@merck.com<\/td><\/tr><tr><td><strong>Spain<\/strong>Merck Sharp &amp; Dohme de Espa\u00f1a, SAPhone: +34 91 321 06 00msd_info@merck.com<\/td><td><strong>Polish<\/strong>MSD Polska Sp.&nbsp;z o. oTel.: +48.22.549.51.00msdpolska@merck.com<\/td><\/tr><tr><td><strong>France<\/strong>MSD FranceTel: +33 (0) 1 80 46 40 40<\/td><td><strong>Portugal<\/strong>Merck Sharp &amp; Dohme, LdaPhone: +351 21 4465700inform_pt@merck.com<\/td><\/tr><tr><td><strong>Hrvatska<\/strong>Merck Sharp &amp; Dohme dooPhone: +385 1 66 11 333croatia_info@merck.com<\/td><td><strong>Romania<\/strong>Merck Sharp &amp; Dohme Romania SRLPhone: + 4021 529 29 00msdromania@merck.com<\/td><\/tr><tr><td><strong>Ireland<\/strong>Merck Sharp &amp; Dohme Ireland (&nbsp;Human&nbsp;Health) LimitedPhone: +353 (0)1 2998700medinfo_ireland@merck.com<\/td><td><strong>Slovenija<\/strong>Merck Sharp &amp; Dohme, inovativna svlad\u00edva dooPhone: +386.1.520.4201msd.slovenia@merck.com<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hf.Telephone: + 354 535 7000<\/td><td><strong>Slovenian Republic<\/strong>Merck Sharp &amp; Dohme, s.r.oPhone: +421 2 58282010dpoc_czechslovak@merck.com<\/td><\/tr><tr><td><strong>Italy<\/strong>MSD Italia SrlTel: +39 06 361911 medicalinformation.it@merck.com<\/td><td><strong>Finland\/Finland<\/strong>MSD Finland OyPhone\/Tel: +358 (0)9 804 650info@msd.fi<\/td><\/tr><tr><td><strong>Cyprus<\/strong>Merck Sharp &amp; Dohme Cyprus LimitedTel: 800 00 673 (+357 22866700)cyprus_info@merck.com<\/td><td><strong>Sweden<\/strong>Merck Sharp &amp; Dohme (Sweden) ABPhone: +46 77 5700488medicalinfo@merck.com<\/td><\/tr><tr><td><strong>Latvia<\/strong>SIA Merck Sharp &amp; Dohme LatvijaPhone: +371.67364.224msd_lv@merck.com<\/td><td><strong>United Kingdom (Northern Ireland)<\/strong>Merck Sharp &amp; Dohme Ireland (&nbsp;Human&nbsp;Health) LimitedPhone: +353 (0)1 2998700medinfoNI@msd.com<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Vaxneuvance is a pneumococcal vaccine given to adults from the age of 18 to protect against diseases caused by 15 types of the bacterium\u00a0Streptococcus pneumoniae\u00a0, also called &#8220;pneumococcus&#8221;.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[27155,27153,27154,27158,27161,27159,27157,27160,27156,27162],"class_list":["post-27288","post","type-post","status-publish","format-standard","hentry","category-medicines","category-v","tag-benefits-of-pneumococcal-polysaccharide-vaccine","tag-pneumococcal-polysaccharide-vaccine","tag-pneumococcal-polysaccharide-vaccine-side-effects","tag-vaxneuvance","tag-vaxneuvance-side-effects","tag-vaxneuvance-vaccine","tag-what-is-pneumococcal-polysaccharide-vaccine","tag-what-is-vaxneuvance","tag-what-pneumococcal-polysaccharide-vaccine-is-used-for","tag-what-vaxneuvance-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/27288","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=27288"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/27288\/revisions"}],"predecessor-version":[{"id":27366,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/27288\/revisions\/27366"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=27288"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=27288"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=27288"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}