{"id":26544,"date":"2022-10-14T14:45:42","date_gmt":"2022-10-14T14:45:42","guid":{"rendered":"https:\/\/zeepedia.com\/?p=26544"},"modified":"2022-10-18T07:43:39","modified_gmt":"2022-10-18T07:43:39","slug":"vancomycin-xellia","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/vancomycin-xellia\/","title":{"rendered":"Vancomycin Xellia &#8211; Vancomycin hydrochloride uses, dose and side effects"},"content":{"rendered":"\n<p>125 mg and 250 mg&nbsp;hard capsules<br>vancomycin hydrochloride<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Vancomycin Xellia is and what it is used for<\/h2>\n\n\n\n<p>Vancomycin is an\u00a0antibiotic\u00a0that belongs to a group of\u00a0antibiotics\u00a0called &#8220;glycopeptides&#8221;.\u00a0Vancomycin works by killing certain bacteria that cause your\u00a0infection.<\/p>\n\n\n\n<p>Vancomycin is used in adults and adolescents from the age of 12 for the treatment of\u00a0infection\u00a0in the mucosa of the small and large intestine with damage to the mucosa (pseudomembranous\u00a0colitis\u00a0), which is caused by the bacterium\u00a0Clostridium difficile.<\/p>\n\n\n\n<p>The vancomycin contained in Vancomycin Xellia may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Vancomycin Xellia<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Vancomycin Xellia<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to vancomycin or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using Vancomycin Xellia if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You have ever had a severe skin rash or scaly skin, blisters, and\/or sores in your mouth after taking vancomycin?<\/li><\/ul>\n\n\n\n<p>Serious skin reactions including\u00a0Stevens-Johnson syndrome,\u00a0toxic epidermal necrolysis, drug reaction with\u00a0eosinophilia\u00a0and systemic symptoms (DRESS), and\u00a0acute\u00a0generalized exanthematous\u00a0pustulosis\u00a0(AGEP) have been reported in association with vancomycin treatment.\u00a0Stop using vancomycin and contact your doctor immediately if you notice any of the symptoms described in section 4.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You have an\u00a0inflammatory\u00a0disease of the gastrointestinal tract (you may be at risk of\u00a0side effects, especially if you also have kidney disease).\u00a0Vancomycin capsules are not suitable for children under 12 years of age or for adolescents who cannot swallow them.\u00a0Other formulations of this medicine may be more suitable for children.\u00a0Ask your doctor or pharmacist.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Vancomycin Xellia<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are using, have recently used, or might be using other medicines.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Limited experience of use during pregnancy.\u00a0If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using Vancomycin Xellia.<\/p>\n\n\n\n<p>Vancomycin is excreted in breast milk.&nbsp;Therefore, consult a doctor&nbsp;<em>before<\/em>&nbsp;starting treatment with Vancomycin Xellia capsules while breastfeeding.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>In rare cases, vancomycin can cause dizziness and lightheadedness.&nbsp;Do not drive or use machines if you are affected.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0The description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Vancomycin Xellia<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Adults and adolescents (from 12 years and older)<\/strong><\/p>\n\n\n\n<p>The recommended\u00a0dose\u00a0is 125 mg every 6 hours.\u00a0In some cases, the doctor may decide to give a higher daily\u00a0dose\u00a0of up to 500 mg every 6 hours.\u00a0The maximum daily\u00a0dose\u00a0must not exceed 2 g.<\/p>\n\n\n\n<p>If you have had a mucosal&nbsp;infection&nbsp;before, you may need a different&nbsp;dose&nbsp;and a different treatment time.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use too much Vancomycin Xellia &nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the drug by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Vancomycin Xellia<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for the\u00a0missed dose.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Mode of administration<\/h2>\n\n\n\n<p>To be swallowed.<\/p>\n\n\n\n<p>Swallow the capsules whole with water.<\/p>\n\n\n\n<p>The usual duration of treatment is 10 days but may vary depending on the individual response to treatment for each patient.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Vancomycin can cause allergic reactions, although serious allergic reactions (anaphylactic\u00a0shock\u00a0) are rare.\u00a0Contact a doctor immediately if you suddenly experience wheezing, difficulty breathing,\u00a0redness\u00a0of the upper body, rash,<\/strong> or\u00a0itching<strong>.<br><br>Stop using vancomycin and contact your doctor immediately if you notice any of the following symptoms:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Red, non-raised, target-like, or round spots on the trunk, often with blisters in the center, scaly skin, and sores in the mouth, throat, nose, genitals, and eyes.\u00a0These severe skin rashes may be preceded by fever and\u00a0flu-like symptoms\u00a0(\u00a0Stevens-Johnson syndrome\u00a0and\u00a0toxic epidermal necrolysis\u00a0).<\/li><li>Widespread rash, fever, and enlarged\u00a0lymph nodes\u00a0(DRESS syndrome or drug hypersensitivity syndrome).\u00a0\u2022 Red, widespread and scaly rash with subcutaneous nodules and blisters along with fever that occurs at the beginning of treatment (\u00a0Acute\u00a0generalized exanthematous\u00a0pustulosis\u00a0)<\/li><\/ul>\n\n\n\n<p>Absorption of vancomycin from the gastrointestinal tract is negligible.&nbsp;Therefore,&nbsp;side effects&nbsp;after taking capsules are unlikely.<\/p>\n\n\n\n<p>However, if you have an\u00a0inflammatory\u00a0disease of the gastrointestinal tract, especially if you also have kidney disease,\u00a0side effects\u00a0similar to those that occur when vancomycin is given by\u00a0infusion\u00a0may occur.\u00a0Therefore,\u00a0side effects\u00a0and frequencies reported for vancomycin as\u00a0an infusion\u00a0are included.<\/p>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drop in blood pressure<\/li><li>Shortness of breath, noisy breathing (a raspy sound that occurs due to obstructed airflow in the upper airways)<\/li><li>Rash and\u00a0inflammation\u00a0of the mucous membrane of the mouth,\u00a0itching, itchy rash,\u00a0hives<\/li><li>Kidney problems that can be seen mainly through blood tests<\/li><li>Redness\u00a0on the upper body and face,\u00a0inflammation\u00a0of a vein<\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Temporary or permanent hearing loss<\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Decrease in\u00a0white blood cells,\u00a0red blood cells,\u00a0and\u00a0platelets\u00a0(blood cells responsible for blood clotting)Increase in certain\u00a0white blood cells\u00a0in the blood<\/li><li>Loss of balance, ringing in the ears, dizziness<\/li><li>Vascular inflammation<\/li><li>Nausea<\/li><li>Inflammation\u00a0of the kidneys and\u00a0kidney failure<\/li><li>Pain in chest and back muscles<\/li><li>Fever, chills<\/li><\/ul>\n\n\n\n<p><strong>Very rare&nbsp;side effects&nbsp;(may affect up to 1 in 10,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sudden onset severe allergic skin reaction with peeling skin, blisters, or peeling.\u00a0This may be associated with high fever and joint pain<\/li><li>Cardiac arrest<\/li><li>Inflammation\u00a0of the intestine causes abdominal pain and diarrhea, which may contain blood<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurring in an unknown number of people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vomiting, diarrhea<\/li><li>Confusion, drowsiness, lack of energy, swelling,\u00a0fluid retention, decreased urine<\/li><li>Eruptions with swelling or pain behind the ears, in the neck, groin, under the chin, and armpits (swollen\u00a0lymph nodes\u00a0), abnormal blood and liver function tests<\/li><li>Rash with blisters and fever,<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Vancomycin Xellia<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>The capsules were used before the expiry date on the packaging.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>The active substance is vancomycin hydrochloride.<\/p>\n\n\n\n<p>125 mg: 1 capsule contains 125 mg vancomycin hydrochloride equivalent to 125,000 IU vancomycin.<\/p>\n\n\n\n<p>250 mg: 1 capsule contains 250 mg vancomycin hydrochloride equivalent to 250,000 IU vancomycin.<\/p>\n\n\n\n<p><em>Other ingredients:<\/em>&nbsp;<\/p>\n\n\n\n<p>Macrogol 6000. The capsule consists of gelatin and the dyes black and yellow iron oxide (E172) and titanium dioxide E171.&nbsp;Capsules 250 mg also contain the dye indigo carmine (E132).<\/p>\n\n\n\n<p><em>Ink:<\/em><\/p>\n\n\n\n<p><em>Capsule 125 mg:<\/em>&nbsp;Shellac, propylene glycol, ammonia, potassium hydroxide, black iron oxide (E172).&nbsp;<em>Capsule 250 mg:<\/em>&nbsp;Shellac, propylene glycol, sodium hydroxide, povidone, titanium dioxide (E171).<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>The 125 mg capsule is light grey\/grey and marked Vanco\/125 mg.<\/p>\n\n\n\n<p>The 250 mg capsule is green\/turquoise and labeled Vanco\/250 mg.<\/p>\n\n\n\n<p>Blister pack with 28 capsules<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p>Xellia Pharmaceuticals ApS<\/p>\n\n\n\n<p>Dalslandsgade 11<\/p>\n\n\n\n<p>2300 Copenhagen S<\/p>\n\n\n\n<p>Denmark<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vancomycin is an\u00a0antibiotic\u00a0that belongs to a group of\u00a0antibiotics\u00a0called &#8220;glycopeptides&#8221;.\u00a0Vancomycin works by killing certain bacteria that cause your\u00a0infection\u00a0.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[26978,26983,26981,26982,26984,26988,26987,26979,26985,26980,26986],"class_list":["post-26544","post","type-post","status-publish","format-standard","hentry","category-medicines","category-v","tag-vancomycin-hydrochloride","tag-vancomycin-hydrochloride-benefits","tag-vancomycin-hydrochloride-capsule","tag-vancomycin-hydrochloride-side-effects","tag-vancomycin-xellia","tag-vancomycin-xellia-capsules","tag-vancomycin-xellia-side-effects","tag-what-is-vancomycin-hydrochloride","tag-what-is-vancomycin-xellia","tag-what-vancomycin-hydrochloride-is-used-for","tag-what-vancomycin-xellia-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26544","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=26544"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26544\/revisions"}],"predecessor-version":[{"id":27032,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26544\/revisions\/27032"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=26544"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=26544"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=26544"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}