{"id":26541,"date":"2022-10-14T14:15:42","date_gmt":"2022-10-14T14:15:42","guid":{"rendered":"https:\/\/zeepedia.com\/?p=26541"},"modified":"2022-10-18T07:43:50","modified_gmt":"2022-10-18T07:43:50","slug":"vancocin","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/vancocin\/","title":{"rendered":"Vancocin &#8211; Vancomycin uses, dose and side effects"},"content":{"rendered":"\n<p>125 mg&nbsp;Capsules&nbsp;<\/p>\n\n\n\n<p>Vancomycin<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Vancocin is and what it is used for<\/h2>\n\n\n\n<p>Vancocin contains vancomycin, which is an\u00a0antibiotic\u00a0that belongs to a group of\u00a0antibiotics\u00a0called &#8216;glycopeptides&#8217;.\u00a0Vancomycin works by killing certain bacteria that cause your\u00a0infection.<\/p>\n\n\n\n<p>Vancocin is used in adults and adolescents from the age of 12 for the treatment of\u00a0infection\u00a0in the mucosa of the small and large intestine with damage to the mucosa (pseudomembranous\u00a0colitis\u00a0), which is caused by the bacterium\u00a0\u00a0<em>Clostridium difficile<\/em>.<\/p>\n\n\n\n<p>The vancomycin contained in Vancocin may also be approved to treat other conditions not listed in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Vancocin<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Vancocin<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are hypersensitive to vancomycin or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before taking Vancocin if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have reduced kidney function<\/li><li>have problems with the ears, such as hearing loss<\/li><li>have an\u00a0inflammatory\u00a0disease of the gastrointestinal tract (you may be at risk of\u00a0side effects, especially if you also have kidney disease)<\/li><li>have ever had a severe skin rash or scaly skin, blisters, and\/or sores in the mouth after taking vancomycin?<\/li><\/ul>\n\n\n\n<p>Serious skin reactions including\u00a0Stevens-Johnson syndrome,\u00a0toxic epidermal necrolysis, drug reaction with\u00a0eosinophilia\u00a0and systemic symptoms (DRESS), and\u00a0acute\u00a0generalized exanthematous\u00a0pustulosis\u00a0(AGEP) have been reported in association with vancomycin treatment.\u00a0Stop using vancomycin and contact your doctor immediately if you notice any of the symptoms described in section 4.<\/p>\n\n\n\n<p>Vancocin capsules are not suitable for children under 12 years of age or for adolescents who cannot swallow them.&nbsp;Other formulations of this medicine may be more suitable for children.&nbsp;Ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Vancocin capsules are not suitable for children under 12 years of age or for adolescents who cannot swallow them.&nbsp;Other formulations of this medicine may be more suitable for children.&nbsp;Ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Vancocin<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Medicines that can damage the kidneys<\/strong>\u00a0(eg aminoglycoside antibiotics, iodinated contrast agents, platinum-based\u00a0chemotherapy\u00a0(cancer medicines), methotrexate at high\u00a0doses, and certain medicines for viral infections such as pentamidine, foscarnet, aciclovir, ganciclovir, famciclovir, valaciclovir, valganciclovir, ciclosporin or tacrolimus).\u00a0If these drugs are given at the same time as vancomycin, the harmful effect on the kidneys may be enhanced.\u00a0In such cases, a careful and regular check of kidney function is necessary.<\/li><li>Medicines that can damage hearing\u00a0(eg\u00a0aminoglycosides, platinum-based\u00a0chemotherapy,\u00a0and some diuretics).\u00a0If these drugs are given at the same time as vancomycin, the harmful effect on hearing may be enhanced.\u00a0In such cases, a careful and regular check of the hearing function is necessary.<\/li><li><strong>Muscle relaxants<\/strong>\u00a0(eg succinylcholine).\u00a0If these drugs are given at the same time as vancomycin, the effect of the muscle relaxant may be enhanced or prolonged.<\/li><\/ul>\n\n\n\n<p>The effect of birth control pills may be reduced when Vancocin is used at the same time.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p>The experience of treatment with vancomycin during pregnancy is limited.\u00a0If you are pregnant, your doctor should only give you vancomycin if necessary and after carefully weighing the benefits and risks.<\/p>\n\n\n\n<p>Vancomycin is excreted in breast milk.&nbsp;Therefore, consult your doctor or pharmacist before starting the treatment.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Vancocin has no known effects on the ability to drive and use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Vancocin<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Adults and adolescents (from 12 years and older)<\/strong><\/p>\n\n\n\n<p>The recommended\u00a0dose\u00a0is 125 mg every 6 hours.\u00a0In some cases, the doctor may decide to give a higher daily\u00a0dose\u00a0of up to 500 mg every 6 hours.\u00a0The maximum daily\u00a0dose\u00a0must not exceed 2 g.<\/p>\n\n\n\n<p>If you have had a mucosal&nbsp;infection&nbsp;before, you may need a different&nbsp;dose&nbsp;and a different treatment time.<\/p>\n\n\n\n<p><strong>Mode of administration<\/strong><\/p>\n\n\n\n<p>To be swallowed.<\/p>\n\n\n\n<p>Swallow the capsules whole with water.<\/p>\n\n\n\n<p>The usual duration of treatment is 10 days but may vary depending on the individual response to treatment for each patient.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you used too much Vancocin &nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Vancocin<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Vancomycin can cause allergic reactions, although serious allergic reactions (anaphylactic\u00a0shock\u00a0) are rare.\u00a0Contact a doctor immediately if you suddenly experience wheezing, difficulty breathing,\u00a0redness\u00a0of the upper body, rash, or itching.<\/strong><\/p>\n\n\n\n<p><strong>Stop using vancomycin and contact your doctor immediately if you notice any of the following symptoms:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Red, non-raised, target-like, or round spots on the trunk, often with blisters in the center, scaly skin, and sores in the mouth, throat, nose, genitals, and eyes.\u00a0These severe skin rashes may be preceded by fever and\u00a0flu-like symptoms\u00a0(\u00a0Stevens-Johnson syndrome\u00a0and\u00a0toxic epidermal necrolysis\u00a0).<\/li><li>Widespread rash, fever, and enlarged\u00a0lymph nodes\u00a0(DRESS syndrome or drug hypersensitivity syndrome).<\/li><li>Red, widespread, and scaly rash with subcutaneous nodules and blisters along with fever that occurs at the beginning of treatment (\u00a0Acute\u00a0generalized exanthematous\u00a0pustulosis\u00a0)<\/li><\/ul>\n\n\n\n<p>Absorption of vancomycin from the gastrointestinal tract is negligible.&nbsp;Therefore,&nbsp;side effects&nbsp;after taking capsules are unlikely.<\/p>\n\n\n\n<p>However, if you have an\u00a0inflammatory\u00a0disease of the gastrointestinal tract, especially if you also have kidney disease,\u00a0side effects\u00a0similar to those that occur when vancomycin is given by\u00a0infusion\u00a0may occur.\u00a0Therefore,\u00a0side effects\u00a0and frequencies reported for vancomycin as\u00a0an infusion\u00a0are included.<\/p>\n\n\n\n<p><strong>Common&nbsp;<\/strong>&nbsp;<strong>side effects&nbsp;(<\/strong>&nbsp;may affect up to 1 in 10 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>blood pressure drop<\/li><li>shortness of breath, noisy breathing (a raspy sound that occurs due to obstructed airflow in the upper airways)<\/li><li>rash and\u00a0inflammation\u00a0of the mucous membrane of the mouth,\u00a0itching, itchy rash,\u00a0hives<\/li><li>kidney problems that can be seen mainly through blood tests<\/li><li>redness\u00a0on the upper body and face,\u00a0inflammation\u00a0of a vein.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(<\/strong>&nbsp;may affect up to 1 in 100 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>temporary or permanent hearing loss.<\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;(<\/strong>&nbsp;may affect up to 1 in 1,000 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>decrease in\u00a0white blood cells,\u00a0red blood cells,\u00a0and\u00a0platelets\u00a0(blood cells responsible for blood clotting)<\/li><li>increase in certain\u00a0white blood cells\u00a0in the blood<\/li><li>loss of balance, ringing in the ears, dizziness<\/li><li>blood vessel inflammation<\/li><li>nausea<\/li><li>inflammation\u00a0of the kidneys and\u00a0kidney failure<\/li><li>pain in chest and back muscles<\/li><li>fever chills.<\/li><\/ul>\n\n\n\n<p><strong>Very rare&nbsp;<\/strong>&nbsp;<strong>side effects&nbsp;(<\/strong>&nbsp;may affect up to 1 in 10,000 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sudden onset severe allergic skin reaction with peeling skin, blisters, or peeling.\u00a0This may be associated with high fever and joint pain<\/li><li>cardiac arrest<\/li><li>inflammation\u00a0of the intestine causing abdominal pain and diarrhea, which may contain blood.<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurring in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>vomiting, diarrhea<\/li><li>confusion, drowsiness, lack of energy, swelling,\u00a0fluid retention, decreased urine<\/li><li>rash with swelling or pain behind the ears, in the neck, groin, under the chin, and armpits (swollen\u00a0lymph nodes\u00a0), abnormal blood and liver function tests<\/li><li>rash with blisters and fever.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Vancocin<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use before the expiry date which is stated on the blister and the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is vancomycin hydrochloride equivalent to 125 mg of vancomycin.<\/li><li>Other ingredients are macrogol 6000, and gelatin;\u00a0the capsule dyes:\u00a0indigo carmine (E132), red and yellow iron oxide (E172), and titanium dioxide (E171);\u00a0<em>labeling on the capsule:<\/em>\u00a0Industrial methyl alcohol, shellac, red iron oxide (E 172), 2-ethoxyethanol, purified water, soy lecithin, Antifoam DC1510.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>The capsules are blue\/brown, 18 x 6 mm, and marked 125.<\/p>\n\n\n\n<p>30 capsules in printed packaging<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>STADA Nordic ApS<\/p>\n\n\n\n<p>Marielundvej 46A<\/p>\n\n\n\n<p>2730 Herlev<\/p>\n\n\n\n<p>Denmark<\/p>\n\n\n\n<p><strong>Manufacturer:<\/strong><\/p>\n\n\n\n<p>STADA Arzneimittel AG<\/p>\n\n\n\n<p>Stadastrasse 2-18<\/p>\n\n\n\n<p>61118 Bad Vilbel<\/p>\n\n\n\n<p>Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vancocin contains vancomycin, which is an\u00a0antibiotic\u00a0that belongs to a group of\u00a0antibiotics\u00a0called &#8216;glycopeptides&#8217;.\u00a0Vancomycin works by killing certain bacteria that cause your\u00a0infection\u00a0.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[27002,27007,27008,26999,27003,27005,27004,27000,27006,27001],"class_list":["post-26541","post","type-post","status-publish","format-standard","hentry","category-medicines","category-v","tag-vancocin","tag-vancocin-capsule","tag-vancocin-side-effects","tag-vancomycin","tag-vancomycin-capsule","tag-vancomycin-side-effects","tag-what-is-vancocin","tag-what-is-vancomycin","tag-what-vancocin-is-used-for","tag-what-vancomycin-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26541","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=26541"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26541\/revisions"}],"predecessor-version":[{"id":27034,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26541\/revisions\/27034"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=26541"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=26541"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=26541"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}