{"id":26409,"date":"2022-10-13T09:22:44","date_gmt":"2022-10-13T09:22:44","guid":{"rendered":"https:\/\/zeepedia.com\/?p=26409"},"modified":"2022-10-14T12:18:43","modified_gmt":"2022-10-14T12:18:43","slug":"valsartan-hydrochlorothiazide-rivopharm","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/valsartan-hydrochlorothiazide-rivopharm\/","title":{"rendered":"Valsartan\/Hydrochlorothiazide Rivopharm &#8211; Hydrochlorothiazide uses, dose and side effects"},"content":{"rendered":"\n<p>80mg\/12.5mg;&nbsp;160 mg\/12.5 mg , 160 mg\/25 mg&nbsp;film-coated tablets<br>valsartan\/hydrochlorothiazide<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Valsartan\/Hydrochlorothiazide Rivopharm is and what it is used for<\/h2>\n\n\n\n<p>Valsartan\/Hydrochlorothiazide Rivopharm film-coated tablets contain two active substances, valsartan and&nbsp;hydrochlorothiazide&nbsp;.&nbsp;Both substances help to control high&nbsp;blood pressure&nbsp;(&nbsp;hypertension&nbsp;).<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Valsartan<\/strong>\u00a0belongs to a group of drugs called &#8220;angiotensin II receptor blockers&#8221; and is used to lower high\u00a0blood pressure.\u00a0Angiotensin\u00a0II is a substance found in the body that constricts the blood vessels, which increases\u00a0blood pressure\u00a0et.\u00a0Valsartan works by\u00a0inhibiting\u00a0the effect of\u00a0angiotensin\u00a0II.\u00a0This leads to\u00a0vessels\u00a0dilating and\u00a0blood pressure\u00a0falling.<\/li><li><strong>Hydrochlorothiazide<\/strong>\u00a0belongs to a group of drugs called thiazide diuretics (also called diuretics).\u00a0Hydrochlorothiazide\u00a0increases urine production, which also lowers\u00a0blood pressure\u00a0et.<\/li><\/ul>\n\n\n\n<p>Valsartan\/Hydrochlorothiazide Rivopharm is used to treat high&nbsp;blood pressure&nbsp;that cannot be lowered sufficiently with just one of the substances.<\/p>\n\n\n\n<p>High\u00a0blood pressure\u00a0increases the load on the heart and blood\u00a0vessels.\u00a0If left untreated, it can damage the blood vessels in the brain, heart, and kidneys, and lead to stroke,\u00a0heart\u00a0failure,\u00a0or\u00a0kidney failure.\u00a0High\u00a0blood pressure\u00a0increases the risk of a heart attack.\u00a0A lowering of\u00a0blood pressure\u00a0et to a normal level reduces the risk of these diseases.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Valsartan\/Hydrochlorothiazide Rivopharm<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Valsartan\/Hydrochlorothiazide Rivopharm<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to valsartan,\u00a0hydrochlorothiazide, sulfonamide derivatives (substances chemically related to\u00a0hydrochlorothiazide\u00a0), soya oil, peanut oil, or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have been\u00a0pregnant for more than three months: Pregnant women should not use Valsartan\/Hydrochlorothiazide Rivopharm during the last 6 months of pregnancy (even earlier in pregnancy it is better to avoid Valsartan\/Hydrochlorothiazide Rivopharm &#8211; see Pregnancy and breast-feeding).<\/li><li>if you have\u00a0severe\u00a0liver disease, the destruction of the small bile ducts in the liver (\u00a0biliary cirrhosis\u00a0) leads to a build-up of bile in the liver (cholestasis).<\/li><li>if you have\u00a0severe\u00a0kidney disease.<\/li><li>if you cannot empty your bladder.<\/li><li>if you are being treated with an artificial kidney.<\/li><li>if your\u00a0potassium\u00a0or sodium level in the blood is lower than normal or if the calcium level in the blood is higher than normal despite treatment.<\/li><li>if you have\u00a0gout.<\/li><li>if you have\u00a0diabetes\u00a0or impaired kidney function and you are being treated with an antihypertensive medicine containing aliskiren.<\/li><\/ul>\n\n\n\n<p><strong>If any of the above applies to you, you should not take this medicine.&nbsp;Talk to your doctor.<\/strong><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p><strong>Talk to your doctor, pharmacist, or nurse before taking Valsartan\/Hydrochlorothiazide Rivopharm, especially:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are taking potassium-sparing medicines, potassium supplements, salt substitutes containing\u00a0potassium,\u00a0or other medicines that increase the amount of\u00a0potassium\u00a0in the blood, for example,\u00a0heparin.\u00a0Your doctor may need to check the amount of\u00a0potassium\u00a0in your blood regularly.<\/li><li>if you have low levels of potassium in your blood.<\/li><li>if you have diarrhea or severe vomiting.<\/li><li>if you take high\u00a0doses\u00a0of water-reducing tablets (\u00a0diuretics\u00a0).<\/li><li>if you have a serious heart condition.<\/li><li>if you have\u00a0heart failure\u00a0or have had a heart attack.\u00a0Follow your doctor&#8217;s instructions for the starting dose carefully.\u00a0Your doctor may also check your kidney function.<\/li><li>if you have a narrowing of the renal arteries.<\/li><li>if you have recently received a new kidney.<\/li><li>if you have hyperaldosteronism.\u00a0This is a disease in which your adrenal glands produce too much of\u00a0the\u00a0hormone\u00a0aldosterone.\u00a0If this applies to you, Valsartan\/Hydrochlorothiazide Rivopharm is not recommended.<\/li><li>if you have liver or kidney disease.<\/li><li>if you have ever experienced swelling of the tongue and face caused by an\u00a0allergic reaction\u00a0called angioedema\u00a0while\u00a0taking another medicine (including\u00a0ACE inhibitors\u00a0), talk to your doctor.\u00a0If these symptoms occur while taking Valsartan\/Hydrochlorothiazide Rivopharm, stop taking Valsartan\/Hydrochlorothiazide Rivopharm immediately and never take it again.\u00a0See also section 4.<\/li><li>if you have a fever, rash, and joint pain, which may be signs of systemic lupus erythematosus (\u00a0SLE, a so-called\u00a0autoimmune\u00a0disease).<\/li><li>if you have\u00a0diabetes,\u00a0gout, high cholesterol levels, or high blood lipids.<\/li><li>if you have had an\u00a0allergic reaction\u00a0when using other blood pressure-lowering agents belonging to this drug group (\u00a0angiotensin\u00a0II receptor blockers) or if you have\u00a0allergies\u00a0or\u00a0asthma.<\/li><li>if you experience impaired vision or eye pain.\u00a0These may be symptoms of fluid accumulation in the eye (between the choroid and sclera) or an increase in pressure in the eye and may occur within hours to weeks of taking Valsartan\/Hydrochlorothiazide Rivopharm.\u00a0This can lead to permanent vision loss if left untreated.\u00a0If you have previously had a\u00a0penicillin\u00a0or sulfonamide allergy, you may be at greater risk of developing this.<\/li><li>it can increase the skin&#8217;s sensitivity to the sun.<\/li><li>if you have had skin cancer or if you get an unexpected skin change during treatment.\u00a0Treatment with hydrochlorothiazide, especially long-term use at high\u00a0doses, may increase the risk of certain types of skin and lip cancer (non-melanoma\u00a0skin cancer).\u00a0Protect your skin from exposure to sunlight and UV rays while taking Valsartan\/Hydrochlorothiazide Rivopharm.<\/li><li>if you are taking any of the following medicines used to treat high blood pressure:<ul><li>an\u00a0ACE inhibitor\u00a0(eg\u00a0enalapril, lisinopril, ramipril), especially if you have diabetes-related kidney problems.<\/li><li>the aliskiren<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>Your doctor may need to check your kidney function,\u00a0blood pressure,\u00a0and the number of\u00a0electrolytes\u00a0(eg\u00a0potassium\u00a0) in your blood at regular intervals.<\/p>\n\n\n\n<p>See also the information under the heading &#8220;Do not take Valsartan\/Hydrochlorothiazide Rivopharm&#8221;.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Use of Valsartan\/Hydrochlorothiazide Rivopharm in children and adolescents (younger than 18 years) is not recommended.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Valsartan\/Hydrochlorothiazide Rivopharm<\/h2>\n\n\n\n<p><strong>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/strong><\/p>\n\n\n\n<p>The treatment effect can be affected if Valsartan\/Hydrochlorothiazide Rivopharm is taken together with certain other medicines.\u00a0It may be necessary to change the\u00a0dose, take other precautions or, in some cases, stop treatment with one of the drugs.\u00a0This applies in particular to the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>lithium, a drug used to treat certain types of mental illness<\/li><li>medicines or substances that can increase the amount of\u00a0potassium\u00a0in the blood.\u00a0These include potassium supplements or salt substitutes containing\u00a0potassium, potassium-sparing drugs, and\u00a0heparin<\/li><li>medicines that can lower the amount of\u00a0potassium\u00a0in the blood (\u00a0hypokalemia\u00a0), e.g.\u00a0diuretics\u00a0(water tablets),\u00a0corticosteroids\u00a0(eg prednisone), some\u00a0laxatives\u00a0(eg castor oil), ACTH (a\u00a0hormone\u00a0), carbenoxolone (used to treat mouth ulcers), amphotericin (an antifungal medicine),\u00a0penicillin\u00a0G (an\u00a0antibiotic\u00a0), salicylic acid and closely related substances.<\/li><li>certain\u00a0antibiotics\u00a0(rifamycin group), a medicine used to protect against transplant rejection (ciclosporin), or an antiretroviral medicine for\u00a0HIV\u00a0\/AIDS\u00a0infection\u00a0(ritonavir).\u00a0These medicines can increase the effect of Valsartan\/Hydrochlorothiazide Rivopharm<\/li><li>medicines that can cause &#8220;torsades de pointes&#8221; (irregular heart rhythm), e.g.\u00a0antiarrhythmics\u00a0(medicines used to treat heart problems) and some antipsychotics<\/li><li>medicines that can reduce the amount of\u00a0sodium\u00a0in the blood, e.g.\u00a0antidepressants, antipsychotics,\u00a0antiepileptics<\/li><li>medicines for\u00a0gout, e.g.\u00a0allopurinol, probenecid, sulfinpyrazone<\/li><li>therapeutic\u00a0vitamin D\u00a0and calcium supplements<\/li><li>diabetes medications (oral agents, eg\u00a0metformin\u00a0or\u00a0insulin\u00a0er)<\/li><li>other antihypertensive medicines including methyldopa,\u00a0ACE inhibitors\u00a0(such as\u00a0enalapril, lisinopril, etc.), or aliskiren (see also information under the headings &#8220;Do not take Valsartan\/Hydrochlorothiazide Rivopharm&#8221; and &#8220;Warnings and precautions&#8221;<\/li><li>medicines to increase\u00a0blood pressure\u00a0et, e.g.\u00a0norepinephrine\u00a0or\u00a0adrenaline<\/li><li>digoxin\u00a0or other\u00a0digitalis glycosides\u00a0(medicines used to treat heart problems)<\/li><li>medicines that can increase blood sugar, e.g.\u00a0diazoxide or\u00a0beta-blockers<\/li><li>cytotoxic drugs (used to treat cancer), e.g.\u00a0methotrexate or cyclophosphamide<\/li><li>pain relievers such as non-steroidal anti-inflammatory drugs (\u00a0NSAIDs\u00a0), including selective\u00a0cyclooxygenase\u00a02 inhibitors (COX 2 inhibitors) and\u00a0aspirin\u00a0more than 3 grams<\/li><li>muscle relaxants, e.g.\u00a0tubocurarine<\/li><li>anticholinergic drugs (agents for the treatment of a variety of disorders, such as gastrointestinal spasms, bladder spasms,\u00a0asthma, motion sickness, muscle spasms,\u00a0Parkinson&#8217;s disease,\u00a0and as an aid to\u00a0anesthesia\u00a0) e.g.\u00a0atropine or bike ride<\/li><li>amantadine (an agent used to prevent\u00a0influenza\u00a0and to treat\u00a0Parkinson&#8217;s disease\u00a0)<\/li><li>cholestyramine and colestipol (medicines used for high levels of blood fats)<\/li><li>ciclosporin, a medicine used in organ transplants to prevent rejection<\/li><li>alcohol, sleeping pills, and anesthetics (drugs with a sleeping or pain-relieving effect used, for example, during surgery)<\/li><li>iodinated contrast agent (agent used in imaging examinations).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Valsartan\/Hydrochlorothiazide Rivopharm with food and alcohol<\/h2>\n\n\n\n<p>You can take Valsartan\/Hydrochlorothiazide Rivopharm regardless of meals.<\/p>\n\n\n\n<p>Avoid drinking alcohol until you have spoken to your doctor.&nbsp;Alcohol can lower&nbsp;blood pressure&nbsp;further and\/or increase the risk of you becoming dizzy or fainting.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Tell your doctor if you think you are pregnant or become pregnant during treatment. <\/strong>Your doctor will usually suggest that you stop taking Valsartan\/Hydrochlorothiazide Rivopharm before pregnancy or as soon as you know you are pregnant and will recommend another medicine for you instead.\u00a0Valsartan\/Hydrochlorothiazide Rivopharm is not recommended in early pregnancy and should not be used during the last 6 months of pregnancy as it can then cause birth defects.<\/li><li>Tell your doctor if you are breastfeeding or intend to start breastfeeding.Valsartan\/Hydrochlorothiazide Rivopharm is not recommended for mothers who are breastfeeding and your doctor may choose another treatment for you if you wish to breastfeed your baby, especially if your baby is a newborn or was born prematurely.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Before you drive, use tools or machines, or perform activities that require concentration, make sure you know how Valsartan\/Hydrochlorothiazide Rivopharm affects you.\u00a0Like many other medicines for the treatment of high\u00a0blood pressure, Valsartan\/Hydrochlorothiazide Rivopharm can rarely cause dizziness and affect the ability to concentrate.\u00a0You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Description of these effects and\u00a0side effects are found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with a doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Valsartan\/Hydrochlorothiazide Rivopharm contains lactose<\/h2>\n\n\n\n<p>If you have an intolerance to certain sugars, you should consult your doctor before taking this medicine.<\/p>\n\n\n\n<p><strong>Valsartan\/Hydrochlorothiazide Rivopharm contains soybean oil<\/strong><\/p>\n\n\n\n<p>Valsartan\/Hydrochlorothiazide Rivopharm contains soybean oil.&nbsp;If you are allergic to peanuts or soya, you should not take this medicine.<\/p>\n\n\n\n<p><strong>Valsartan\/Hydrochlorothiazide Rivopharm contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>Valsartan\/Hydrochlorothiazide Rivopharm contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per film-coated tablet, i.e. almost &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<p><strong>Valsartan\/Hydrochlorothiazide Rivopharm contains paraorange (E110)<\/strong><\/p>\n\n\n\n<p>This can cause allergic reactions.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Valsartan\/Hydrochlorothiazide Rivopharm<\/h2>\n\n\n\n<p>Always take Valsartan\/Hydrochlorothiazide Rivopharm as directed by your doctor.\u00a0It will give the best result and reduce the risk of\u00a0side effects.\u00a0Ask your doctor or pharmacist if you are unsure.\u00a0People with high\u00a0blood pressure\u00a0often do not experience any symptoms of this.\u00a0Many feel as usual.\u00a0It is therefore important that you go to your doctor&#8217;s appointments as planned, even if you feel well.<\/p>\n\n\n\n<p>Your doctor will tell you how many Valsartan\/Hydrochlorothiazide Rivopharm tablets to take.\u00a0Depending on the treatment result, the doctor can raise or lower the\u00a0dose.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;of Valsartan\/Hydrochlorothiazide Rivopharm is one tablet per day.<\/li><li>Do not change the&nbsp;dose&nbsp;or stop the treatment without consulting the doctor first.<\/li><li>The medicine should be taken at the same time every day, normally in the morning.<\/li><li>You can take Valsartan\/Hydrochlorothiazide Rivopharm with or without food.<\/li><li>Swallow Valsartan\/Hydrochlorothiazide Rivopharm with a glass of water.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Valsartan\/Hydrochlorothiazide Rivopharm<\/h2>\n\n\n\n<p>If you experience severe dizziness and\/or fainting, lie down and contact a doctor immediately.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has ingested the drug by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Valsartan\/Hydrochlorothiazide Rivopharm<\/h2>\n\n\n\n<p>If you forget to take a\u00a0dose, take it as soon as you remember.\u00a0If it is almost time for the next\u00a0dose, then skip the missed\u00a0dose.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Valsartan\/Hydrochlorothiazide Rivopharm<\/h2>\n\n\n\n<p>If you stop your treatment with Valsartan\/Hydrochlorothiazide Rivopharm, your high&nbsp;blood pressure&nbsp;may get worse.&nbsp;Do not stop taking your medicine unless your doctor tells you to stop.<\/p>\n\n\n\n<p><strong>If you have further questions about this medicine, contact your doctor, pharmacist, or nurse.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be serious and require immediate medical attention:<\/strong><\/p>\n\n\n\n<p>You should contact your doctor immediately if you experience symptoms of\u00a0angioedema, such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swollen face, tongue, or throat<\/li><li>difficulty swallowing<\/li><li>hives\u00a0and difficulty breathing.<\/li><\/ul>\n\n\n\n<p><strong>If you get any of these symptoms, stop taking Valsartan\/Hydrochlorothiazide Rivopharm and contact your doctor immediately (see section 2)<\/strong><\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are:<\/strong><\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 users)<\/em>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>cough<\/li><li>low\u00a0blood pressure<\/li><li>dizzy<\/li><li>dehydration (with symptoms such as thirst, dry mouth, and tongue, rarely needing to empty the bladder, dark-colored urine, and dry skin)<\/li><li>pain in the muscles<\/li><li>fatigue<\/li><li>tingling and numbness<\/li><li>blurred vision<\/li><li>noises (such as buzzing and buzzing) in the ears<\/li><\/ul>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 users)<\/em>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness<\/li><li>diarrhea<\/li><li>pain in the joints<\/li><\/ul>\n\n\n\n<p><em>Has been reported (occurring in an unknown number of users)<\/em>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>difficulty breathing<\/li><li>significantly reduced urine output<\/li><li>low level of sodium in the blood (which can trigger nausea, tiredness, confusion, feeling unwell, and cramps)<\/li><li>low level of potassium in the blood (sometimes with muscle weakness, muscle cramps, and abnormal heart rhythm)<\/li><li>low level of\u00a0white blood cells\u00a0in the blood (with symptoms such as fever, skin infections, sore throat or mouth ulcers due to\u00a0infection, weakness)<\/li><li>increased level of bilirubin in the blood (which in severe cases can cause yellow skin and yellow eyes)<\/li><li>increased values \u200b\u200bof urea nitrogen and\u00a0creatinine\u00a0in the blood (which may indicate impaired kidney function)<\/li><li>the increased uric acid level in the blood (which in severe cases can trigger\u00a0gout\u00a0)<\/li><li>syncope\u00a0(fainting)<\/li><\/ul>\n\n\n\n<p><strong>The following side effects have been reported for other products containing only valsartan or hydrochlorothiazide:<\/strong><\/p>\n\n\n\n<p><strong>Valsartan<\/strong><\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 users)<\/em>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>feeling that it is spinning<\/li><li>pain in the abdomen<\/li><\/ul>\n\n\n\n<p><em>Has been reported (occurring in an unknown number of users)<\/em>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>skin rash with or without\u00a0itching\u00a0along with any of the following symptoms: fever, joint pain, muscle pain, swollen\u00a0lymph nodes,\u00a0and\/or\u00a0flu-like symptoms<\/li><li>rash, purple-red spots, fever,\u00a0itching\u00a0(symptoms of\u00a0inflammation\u00a0of the blood vessels)<\/li><li>low\u00a0platelet counts\u00a0(sometimes with unusual bleeding or bruising)<\/li><li>high level of potassium in the blood (sometimes with muscle cramps, abnormal heart rhythm)<\/li><li>allergic reactions (with symptoms such as rash,\u00a0itching, hives, difficulty breathing or difficulty swallowing, and dizziness)<\/li><li>swelling especially in the face and throat, rash,\u00a0itching<\/li><li>elevated liver function values<\/li><li>reduced hemoglobin value and reduced proportion of\u00a0red blood cells\u00a0in the blood (\u00a0both can cause\u00a0anemia in\u00a0severe\u00a0cases )<\/li><li>kidney failure<\/li><li>low level of\u00a0sodium\u00a0in the blood (which can trigger tiredness, confusion, muscle twitching, and\/or seizures in severe cases)<\/li><\/ul>\n\n\n\n<p><strong>Hydrochlorothiazide<\/strong><\/p>\n\n\n\n<p><em>Very common (may affect more than 1 in 10 users)<\/em>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>low level of&nbsp;potassium&nbsp;in the blood<\/li><li>elevated lipid values \u200b\u200bin the blood<\/li><\/ul>\n\n\n\n<p><em>Common (may affect up to 1 in 10 users)<\/em>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>low level of&nbsp;sodium&nbsp;in the blood<\/li><li>low level of&nbsp;magnesium&nbsp;in the blood<\/li><li>high level of&nbsp;uric acid&nbsp;in the blood<\/li><li>itchy rashes and other types of rashes<\/li><li>decreased appetite<\/li><li>slight nausea and vomiting<\/li><li>dullness, fainting when standing up<\/li><li>impotence<\/li><\/ul>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 users)<\/em>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling and blistering of the skin (due to increased sensitivity to the sun)<\/li><li>high level of\u00a0calcium\u00a0in the blood<\/li><li>high blood sugar level<\/li><li>sugar in the urine<\/li><li>deterioration of metabolic diabetes condition<\/li><li>constipation, diarrhea, stomach, and intestinal discomfort, liver disorders (yellow skin or eyes)<\/li><li>irregular heartbeats<\/li><li>headache<\/li><li>sleep disorders<\/li><li>low mood (depression)<\/li><li>low\u00a0platelet counts\u00a0(sometimes with bleeding or bruising under the skin)<\/li><li>dizziness<\/li><li>tingling or numbness<\/li><li>visual disturbances<\/li><\/ul>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 users)<\/em>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>inflammation\u00a0of the blood vessels with symptoms such as rash, red-purple-red spots, fever (\u00a0vasculitis\u00a0)<\/li><li>rash,\u00a0itching, hives, difficulty breathing or swallowing, dizziness (\u00a0hypersensitivity reaction\u00a0)<\/li><li>severe skin disease causing skin rash,\u00a0redness, blisters on the lips, eyes, or mouth, peeling, fever (\u00a0toxic epidermal necrolysis\u00a0)<\/li><li>rash on the face associated with pain in the joints, muscle disease, fever (\u00a0cutaneous\u00a0lupus erythematosus)<\/li><li>severe pain in the upper part of the stomach (\u00a0pancreatitis\u00a0);\u00a0lack of or low values \u200b\u200bof various\u00a0blood\u00a0cells<\/li><li>difficulty breathing<\/li><li>with fever, cough, wheezing, lung infection, and shortness of breath (shortness of breath including\u00a0pneumonitis\u00a0and\u00a0pulmonary edema)<\/li><li>fever, sore throat, more frequent\u00a0infections\u00a0(\u00a0agranulocytosis\u00a0)<\/li><li>pale skin, tiredness, shortness of breath, dark urine (\u00a0hemolytic anemia\u00a0)<\/li><li>fever, sore throat, or mouth sores due to\u00a0infection\u00a0(\u00a0leukopenia\u00a0)<\/li><li>confusion, fatigue, muscle twitching and\u00a0spasms, rapid breathing (hypochloraemic\u00a0alkalosis\u00a0)<\/li><\/ul>\n\n\n\n<p><em>Has been reported (occurring in an unknown number of users)<\/em>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>weakness, bruising and frequent\u00a0infections\u00a0(\u00a0aplastic anemia\u00a0)<\/li><li>severely reduced urine output (possible signs of kidney disease or\u00a0kidney failure\u00a0)<\/li><li>reduced vision or pain in the eyes due to high pressure (possible signs of fluid accumulation in the eye (between the choroid and the sclera) or\u00a0acute\u00a0narrow-angle glaucoma\u00a0)<\/li><li>skin rash,\u00a0redness, blisters on the lips, eyes, or mouth, peeling of the skin, fever (possible signs of erythema multiforme)<\/li><li>skin and lip cancer (non-melanoma\u00a0skin cancer)<\/li><li>muscle cramp<\/li><li>fever (\u00a0pyrexia\u00a0)<\/li><li>weakness (\u00a0asthenia\u00a0)<\/li><\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Valsartan\/Hydrochlorothiazide Rivopharm<\/h2>\n\n\n\n<p>Store out of sight and reach of children.<\/p>\n\n\n\n<p>Blister packs:<\/p>\n\n\n\n<p>Store at a maximum of 30\u00baC.<\/p>\n\n\n\n<p>Cans:<\/p>\n\n\n\n<p>No special storage instructions.\u00a0After the first opening: use within 100 days.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton, blister, and cans after EXP or EXP.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>The medicine must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to deal with medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>&#8211; The active substance is valsartan and\u00a0hydrochlorothiazide.<\/p>\n\n\n\n<p>One film-coated tablet contains 80 mg of valsartan and 12.5 mg&nbsp;of hydrochlorothiazide<\/p>\n\n\n\n<p>One film-coated tablet contains 160 mg of valsartan and 12.5 mg&nbsp;of hydrochlorothiazide<\/p>\n\n\n\n<p>One film-coated tablet contains 160 mg of valsartan and 25 mg&nbsp;of hydrochlorothiazide<\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<p><em>tablet core<\/em>&nbsp;:<\/p>\n\n\n\n<p>&#8211; microcrystalline cellulose,\u00a0lactose monohydrate, croscarmellose sodium, povidone K29\/32, talc, magnesium stearate,\u00a0colloidal\u00a0anhydrous silica<\/p>\n\n\n\n<p><em>Film coating<\/em>&nbsp;:<\/p>\n\n\n\n<p>80\/12.5 mg tablets: poly(vinyl alcohol), talc, titanium dioxide (E171), macrogol 3350, lecithin (contains soybean oil) (E322), red iron oxide (E172), yellow iron oxide (E172), black iron oxide (E172).<\/p>\n\n\n\n<p>160\/12.5 mg tablets: poly(vinyl alcohol), talc, macrogol 3350, titanium dioxide (E171), red iron oxide (E172), para-orange (E110), lecithin (contains soybean oil) (E322).<\/p>\n\n\n\n<p>160\/25 mg tablets: poly(vinyl alcohol), talc, titanium dioxide (E171), macrogol 3350, yellow iron oxide (E172), lecithin (contains soybean oil) (E322), red iron oxide (E172), black iron oxide (E172).<\/p>\n\n\n\n<p><strong>Appearance and package sizes of the medicine<\/strong><\/p>\n\n\n\n<p>Valsartan\/Hydrochlorothiazide Rivopharm 80 mg\/12.5: Pink, oval, biconvex film-coated tablets, diameter 11&#215;5.8 mm, marked &#8220;V&#8221; on one side and &#8220;H&#8221; on the other side.<\/p>\n\n\n\n<p>Valsartan\/Hydrochlorothiazide Rivopharm 160 mg\/12.5 mg: Red, oval, biconvex film-coated tablets, diameter 15 x 6 mm, marked &#8220;V&#8221; on one side and &#8220;H&#8221; on the other side.<\/p>\n\n\n\n<p>Valsartan\/Hydrochlorothiazide Rivopharm 160 mg\/25 mg: Orange, oval, biconvex film-coated tablets, diameter 15 x 6 mm, marked &#8220;V&#8221; on one side and &#8220;H&#8221; on the other side.<\/p>\n\n\n\n<p>Package sizes:<\/p>\n\n\n\n<p>Blisters:<\/p>\n\n\n\n<p>7, 14, 28, 30, 56, 98 and 280 tablets.<\/p>\n\n\n\n<p>Cans:<\/p>\n\n\n\n<p>7, 14, 28, 30, 56, 98, 100 and 280 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder:<\/em><\/p>\n\n\n\n<p>Rivopharm Ltd.<\/p>\n\n\n\n<p>17 Corrig Road<\/p>\n\n\n\n<p>Sandyford, Dublin 18<\/p>\n\n\n\n<p>Ireland<\/p>\n\n\n\n<p><em>Manufacturer:<\/em><\/p>\n\n\n\n<p>Actavis Ltd.<\/p>\n\n\n\n<p>BLB016 Bulebel Industrial Estate<\/p>\n\n\n\n<p>Zejtun ZTN3000<\/p>\n\n\n\n<p>Malta<\/p>\n\n\n\n<p>Balkanpharma Dupnitsa AD<\/p>\n\n\n\n<p>3, Samokovsko Shosse Str.<\/p>\n\n\n\n<p>2600 Dupnitsa<\/p>\n\n\n\n<p>Bulgaria<\/p>\n\n\n\n<p><em>Agent:<\/em><\/p>\n\n\n\n<p>SanoSwiss UAB<\/p>\n\n\n\n<p>Lviv 25-701<\/p>\n\n\n\n<p>LT-09320 Vilnius<\/p>\n\n\n\n<p>Lithuania<\/p>\n\n\n\n<p>info@sanoswiss.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Valsartan\/Hydrochlorothiazide Rivopharm film-coated tablets contain two active substances, valsartan and\u00a0hydrochlorothiazide\u00a0.\u00a0Both substances help to control high\u00a0blood pressure\u00a0(\u00a0hypertension\u00a0).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[3664,26949,26952,4301,4124,5514,7947,26951,4300,26950,4125,10570],"class_list":["post-26409","post","type-post","status-publish","format-standard","hentry","category-medicines","category-v","tag-hydrochlorothiazide","tag-hydrochlorothiazide-rivopharm","tag-hydrochlorothiazide-rivopharm-tablet","tag-hydrochlorothiazide-tablet","tag-valsartan","tag-valsartan-tablet","tag-what-hydrochlorothiazide-is-used-for","tag-what-hydrochlorothiazide-rivopharm-is-used-for","tag-what-is-hydrochlorothiazide","tag-what-is-hydrochlorothiazide-rivopharm","tag-what-is-valsartan","tag-what-valsartan-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26409","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=26409"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26409\/revisions"}],"predecessor-version":[{"id":26529,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26409\/revisions\/26529"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=26409"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=26409"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=26409"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}