{"id":26090,"date":"2022-10-11T12:33:14","date_gmt":"2022-10-11T12:33:14","guid":{"rendered":"https:\/\/zeepedia.com\/?p=26090"},"modified":"2022-10-12T11:22:36","modified_gmt":"2022-10-12T11:22:36","slug":"valcyte","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/valcyte\/","title":{"rendered":"Valcyte &#8211; Valganciclovir uses, dose and side effects"},"content":{"rendered":"\n<p>50 mg\/ml&nbsp;powder for&nbsp;oral&nbsp;solution<br>valganciclovir<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Valcyte is and what it is used for<\/h2>\n\n\n\n<p>Valcyte belongs to a group of drugs that act directly to prevent the multiplication of\u00a0viruses.\u00a0The active ingredient in the powder, valganciclovir, is converted in the body to ganciclovir.\u00a0Ganciclovir prevents a\u00a0virus\u00a0called\u00a0cytomegalovirus\u00a0(\u00a0CMV\u00a0) from multiplying and attacking healthy cells.\u00a0In patients with a weakened immune system,\u00a0CMV\u00a0can cause\u00a0infection\u00a0in the body&#8217;s organs.\u00a0This can be life-threatening.<\/p>\n\n\n\n<p>Valcyte is used for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>treatment of\u00a0CMV\u00a0infection\u00a0in\u00a0the\u00a0retina\u00a0of the eye in adult patients with acquired immunodeficiency syndrome (\u00a0AIDS\u00a0).\u00a0CMV\u00a0&#8211;\u00a0infection\u00a0of the\u00a0retina\u00a0of the eye can cause vision problems and even blindness.<\/li><li>to\u00a0prevent\u00a0CMV\u00a0infection\u00a0in adults and children who are not infected with\u00a0CMV\u00a0and who have received an organ transplant from someone who was infected with\u00a0CMV.<\/li><\/ul>\n\n\n\n<p><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Valcyte<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Valcyte:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to valganciclovir, ganciclovir, or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are breastfeeding.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Valcyte:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to aciclovir, penciclovir, valaciclovir or famciclovir.\u00a0Other drugs are used in viral infections.<\/li><\/ul>\n\n\n\n<p><strong>Take special care with Valcyte<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have too few\u00a0white blood cells,\u00a0red blood cells,\u00a0or\u00a0platelets\u00a0(small cells involved in blood\u00a0clotting\u00a0) in your blood.\u00a0Your doctor will do blood tests before you start taking Valcyte and more tests will be done while you are using the medicine.<\/li><li>if you are undergoing radiation therapy.<\/li><li>if you have kidney problems.\u00a0Your doctor may need to prescribe you a lower\u00a0dose\u00a0and your blood levels may need to be checked frequently during treatment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Valcyte<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, even those without a prescription.<\/p>\n\n\n\n<p>If you take other medicines at the same time as Valcyte, the combination may affect the amount of medicine absorbed into your blood or possibly cause harmful effects.&nbsp;Tell your doctor if you are already taking medicines that contain any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>imipenem-cilastatin (\u00a0antibiotics\u00a0).\u00a0May cause seizures if taken with Valcyte<\/li><li>zidovudine, didanosine, lamivudine, stavudine, tenofovir, abacavir, emtricitabine or similar medicines used to treat\u00a0AIDS<\/li><li>adefovir or other medicines used to treat\u00a0hepatitis\u00a0B<\/li><li>probenecid (medicine for\u00a0gout\u00a0).\u00a0The amount of ganciclovir in the blood may increase if probenecid and Valcyte are taken at the same time<\/li><li>mycophenolate mofetil, ciclosporin, or tacrolimus (used after transplantation)<\/li><li>vincristine, vinblastine, doxorubicin, hydroxyurea, or similar anticancer drugs<\/li><li>trimethoprim, combinations with trimethoprim\/sulfa and dapsone (\u00a0antibiotics\u00a0)<\/li><li>pentamidine (medicine to treat parasites or lung infections)<\/li><li>flucytosine or amphotericin B (antifungal<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Valcyte with food and drink<\/h2>\n\n\n\n<p>Valcyte should be taken with food.&nbsp;If for some reason you cannot eat, you should still take Valcyte as usual.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>You should not take Valcyte if you are pregnant unless your doctor advises you to do so.&nbsp;You must tell your doctor if you are pregnant or planning to become pregnant.&nbsp;Taking Valcyte during pregnancy may harm your unborn baby.<\/p>\n\n\n\n<p>You should not take Valcyte if you are breastfeeding.\u00a0If your doctor wants to start treatment with Valcyte, you must stop breastfeeding before you start taking the medicine.<\/p>\n\n\n\n<p>Women of childbearing potential must use effective contraception while being treated with Valcyte and for at least 30 days after stopping treatment.<\/p>\n\n\n\n<p>Men whose partners could become pregnant should use condoms while being treated with Valcyte and should continue to use condoms for 90 days after treatment ends.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Do not drive or use tools or machines if you feel dizzy, tired, shaky, or confused while taking this medicine.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Valcyte contains sodium benzoate and sodium (salt)<\/h2>\n\n\n\n<p>This medicine contains 100 mg of sodium benzoate in each 12 g bottle, which corresponds to 1 mg\/ml after\u00a0reconstitution.\u00a0Benzoate salt may increase the risk of jaundice (yellowish skin and eyes) in newborns (up to 4 weeks of age).<\/p>\n\n\n\n<p>This medicine contains a total of 0.188 mg\/ml\u00a0sodium, i.e. it is almost &#8220;sodium-free&#8221;.\u00a0This should be taken into account by patients prescribed a low-salt diet.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Valcyte<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>You must handle Valcyte&#8217;s solution carefully.\u00a0You must avoid getting the solution on the skin or in the eyes.\u00a0If you accidentally get a solution on your skin, wash the area thoroughly with soap and water.\u00a0If you accidentally get a solution in your eyes, rinse your eyes thoroughly with water.<\/p>\n\n\n\n<p><strong>You must stick to the daily&nbsp;dose&nbsp;of&nbsp;oral&nbsp;solution prescribed by your doctor to avoid overdose.<\/strong><\/p>\n\n\n\n<p>Valcyte&nbsp;oral&nbsp;solution should, if possible, be taken with food &#8211; see section 2.<\/p>\n\n\n\n<p><strong>You must use<\/strong> the dosing syringe included in the package to measure your\u00a0dose\u00a0of the <strong>Valcyte solution.\u00a0<\/strong><strong>Do not use the dosing syringe with other products.\u00a0<\/strong>Two dosing syringes are included in case one of them is lost or damaged.\u00a0Each dosing syringe is designed to measure up to an amount of 10 ml (500 mg) of solution in 0.5 ml (25 mg) intervals.\u00a01 ml of Valcyte\u00a0oral\u00a0solution is equivalent to 50 mg of valganciclovir.<\/p>\n\n\n\n<p>Always clean the dosing syringe thoroughly and let it dry after taking your\u00a0dose.<\/p>\n\n\n\n<p>Contact a doctor or pharmacist if both dosing syringes are lost or damaged.&nbsp;They will advise how to continue taking your medicine.<\/p>\n\n\n\n<p><strong>Adults:<\/strong><\/p>\n\n\n\n<p><strong>Prevention of&nbsp;CMV&nbsp;disease in organ transplant patients<\/strong><\/p>\n\n\n\n<p>You must start taking this medicine within 10 days of the transplant.\u00a0The usual\u00a0dose\u00a0is 900 mg of Valcyte solution taken ONCE daily.\u00a0Use the dosing syringe provided to take two 9 ml (450 mg)\u00a0doses\u00a0(ie 2 syringes filled to the 9 ml (450 mg) graduation) of solution.\u00a0You should continue this\u00a0dose\u00a0until 100 days after the transplant.\u00a0If you have had a kidney transplant, your doctor may advise you to take one\u00a0dose\u00a0for 200 days.<\/p>\n\n\n\n<p><strong>Treatment of active&nbsp;CMV&nbsp;&#8211;&nbsp;infection&nbsp;in the&nbsp;retina&nbsp;of the eye in patients with&nbsp;AIDS&nbsp;(so-called induction treatment)<\/strong><\/p>\n\n\n\n<p>The usual\u00a0dose\u00a0is 900 mg of Valcyte solution taken TWICE daily for 21 days (three weeks).\u00a0Use the dosing syringe provided and take two\u00a0doses\u00a0of 9 ml (450 mg) (ie 2 syringes filled to the 9 ml (450 mg) graduation) solution in the morning and two\u00a0doses\u00a0of 9 ml (450 mg) (ie two syringes which are filled to the graduation 9 ml (450 mg)) in the evening.<\/p>\n\n\n\n<p>Do not take this&nbsp;dose&nbsp;for more than 21 days unless your doctor tells you to, as your risk of&nbsp;side effects&nbsp;may increase.<\/p>\n\n\n\n<p><strong>Long-term treatment to&nbsp;prevent recurrent active&nbsp;inflammation&nbsp;in&nbsp;AIDS&nbsp;patients with&nbsp;CMV&nbsp;infection&nbsp;in the&nbsp;retina&nbsp;of the eye (so-called maintenance treatment)<\/strong><\/p>\n\n\n\n<p>The usual\u00a0dose\u00a0is 900 mg of Valcyte solution taken ONCE daily.\u00a0Use the dosing syringe provided and take two\u00a0doses\u00a0of 9 ml (450 mg) solution (ie 2 syringes filled to the 9 ml (450 mg) graduation).\u00a0You should try to take the solution at the same time each day.\u00a0Your doctor will tell you how long to continue taking Valcyte.\u00a0If your retinitis worsens while taking this\u00a0dose, your doctor may ask you to repeat the induction treatment (as above) or decide to give you another medicine to treat\u00a0CMV\u00a0infection.<\/p>\n\n\n\n<p><strong>Elderly patients<\/strong><\/p>\n\n\n\n<p>Valcyte has not been studied in elderly patients.<\/p>\n\n\n\n<p><strong>Patients with kidney problems<\/strong><\/p>\n\n\n\n<p>If your kidneys are not fully functioning, your doctor may instruct you to take a lower\u00a0dose\u00a0of Valcyte solution each day.\u00a0You must follow the\u00a0dosage\u00a0prescribed by your doctor.<\/p>\n\n\n\n<p>Use the dosing syringe that comes with the package to measure out\u00a0dose\u00a0one with the Valcyte solution.<\/p>\n\n\n\n<p><strong>Patients with liver problems<\/strong><\/p>\n\n\n\n<p>Valcyte has not been studied in patients with liver problems.<\/p>\n\n\n\n<p><strong>Use for children and adolescents:<\/strong><\/p>\n\n\n\n<p><strong>Prevention of&nbsp;CMV&nbsp;disease in organ transplant patients<\/strong><\/p>\n\n\n\n<p>Children should start taking this medicine within 10 days of the transplant.\u00a0The dose\u00a0given varies depending on the size of the child and should be taken ONCE daily.\u00a0Your doctor will decide on the most appropriate\u00a0dose\u00a0based on your child&#8217;s height, weight, and kidney function.\u00a0You should continue with this\u00a0dose\u00a0up to 100 days after the transplant.\u00a0If your child has received a kidney transplant, your doctor may advise you to take the medicine for 200 days.<\/p>\n\n\n\n<p>Use the dosing syringes included in the package to measure out a&nbsp;dose&nbsp;of Valcyte solution.<\/p>\n\n\n\n<p><strong>Method of administration and route of administration<\/strong><\/p>\n\n\n\n<p>The Valcyte solution is prepared by pharmacists before it is given to you.<\/p>\n\n\n\n<p><em>Once the solution is ready, follow the instructions below to draw up and take your medication.<\/em><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20061128000024#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/d30d38bd-a2ff-4860-9676-23c4b0d4c939\" alt=\"The image describes how the solution should be drawn up into the dosing syringe.\" title=\"The image describes how the solution should be drawn up into the dosing syringe.\"\/><\/a><\/figure>\n\n\n\n<ol class=\"wp-block-list\"><li>Shake the closed bottle well for about 5 seconds before each use.<\/li><li>Remove the childproof cover.<\/li><li>Before the tip of the dosing syringe appears in the bottle adapter, the plunger must be fully pushed in against the tip of the syringe.\u00a0Push the tip of the dosing syringe firmly into the opening of the bottle adapter.<\/li><li>Turn everything (bottle and syringe) upside down.<\/li><li>Slowly pull out the plunger until the desired amount of solution has been drawn up into the dosing syringe (see figure).<\/li><li>Turn the bottle with the dosing syringe back in an upright position and slowly withdraw the syringe from the bottle.<\/li><li>Squirt\u00a0the solution directly into the mouth and swallow.\u00a0Do not mix with other liquids before spraying in the mouth.<\/li><li>Close the bottle with the childproof cap after each use.<\/li><li>Immediately after use: Disassemble the dosing syringe and rinse under running tap water and allow it to air dry before using it again.<\/li><\/ol>\n\n\n\n<p>Be careful and avoid the solution coming into direct contact with the skin.&nbsp;If it does happen, wash thoroughly with soap and water.<\/p>\n\n\n\n<p>Do not use the solution after the expiry date, which is 49 days after\u00a0preparation.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Valcyte<\/h2>\n\n\n\n<p>If you have ingested, or think you have ingested too much medicine or if e.g.\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.\u00a0If you have taken more than the recommended\u00a0dose, you can have serious\u00a0side effects, especially in the blood and kidneys can be affected.\u00a0You may need hospital care.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Valcyte<\/h2>\n\n\n\n<p>If you forget to take Valcyte, take the missed\u00a0dose\u00a0as soon as you remember and take the next\u00a0dose\u00a0at the usual time.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Valcyte<\/h2>\n\n\n\n<p>Do not stop taking this medicine unless your doctor tells you to.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Allergic reactions<\/strong><\/p>\n\n\n\n<p>Up to 1 in 1,000 people may have a sudden and severe&nbsp;allergic reaction&nbsp;to valganciclovir (anaphylactic&nbsp;shock&nbsp;).&nbsp;<strong>STOP<\/strong>&nbsp;taking Valcyte and go to the emergency department of your nearest hospital if you experience any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increasing itchy skin rash (\u00a0hives\u00a0)<\/li><li>sudden swelling of the throat, face, lips, and mouth which may cause difficulty swallowing and breathing<\/li><li>sudden swelling of hands, feet, or ankles<\/li><\/ul>\n\n\n\n<p><strong>Serious&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>Tell your doctor immediately if you notice any of the following serious&nbsp;side effects&nbsp;&#8211; your doctor may tell you to stop taking Valcyte and you may need&nbsp;urgent&nbsp;medical treatment:<\/p>\n\n\n\n<p><strong>Very common:<\/strong>&nbsp;may affect more than 1 in 10 patients<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>low\u00a0white blood cell count\u00a0&#8211; with signs of\u00a0infection\u00a0such as sore throat, mouth sores, or fever<\/li><li>low\u00a0red blood cell count\u00a0&#8211; signs include shortness of breath or tiredness, palpitations, or pale skin<\/li><\/ul>\n\n\n\n<p><strong>Common:<\/strong>&nbsp;may affect 1 to 10 patients<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>blood poisoning (\u00a0sepsis\u00a0) \u2013 signs include fever, chills, palpitations, confusion, and slurred speech<\/li><li>low\u00a0platelet count\u00a0&#8211; signs include bleeding or bruising more easily than usual, blood in the urine or stool, or bleeding from the gums.\u00a0Bleeding can be heavy<\/li><li>severely low blood levels<\/li><li>inflammation\u00a0of the pancreas &#8211; signs are severe abdominal pain that spreads to the back<\/li><li>cramps<\/li><\/ul>\n\n\n\n<p><strong>Uncommon:<\/strong>&nbsp;may affect 1 to 100 patients<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>failure of the bone marrow&#8217;s ability to form&nbsp;blood&nbsp;cells<\/li><li>hallucinations \u2013 hearing or seeing things that are not real<\/li><li>abnormal thoughts or feelings, losing touch with reality<\/li><li>impaired kidney function<\/li><\/ul>\n\n\n\n<p>Side effects&nbsp;that occurred during treatment with valganciclovir or ganciclovir are reported below:<\/p>\n\n\n\n<p><strong>Other\u00a0side effects\u00a0are<\/strong><\/p>\n\n\n\n<p>Tell your doctor, pharmacist, or nurse if you notice any of the following side effects:<\/p>\n\n\n\n<p><strong>Very common:<\/strong>&nbsp;may affect more than 1 in 10 patients<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>mushrooms and cod in the mouth<\/li><li>upper respiratory tract infection (e.g. sinusitis,&nbsp;inflammation&nbsp;of the tonsils)<\/li><li>loss of appetite<\/li><li>headache<\/li><li>cough<\/li><li>shortness of breath<\/li><li>diarrhea<\/li><li>nausea or vomiting<\/li><li>abdominal pain<\/li><li>eczema<\/li><li>fatigue<\/li><li>fever<\/li><\/ul>\n\n\n\n<p><strong>Common:<\/strong>&nbsp;may affect up to 1 in 10 patients<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>influenza<\/li><li>urinary tract infection &#8211; signs include fever, urinating more often than usual, pain when urinating<\/li><li>infection\u00a0in the skin and\u00a0tissues\u00a0under the skin<\/li><li>mild\u00a0allergic reaction\u00a0&#8211; signs may include red and itchy skin<\/li><li>weight loss<\/li><li>feeling depressed, anxious, or confused<\/li><li>sleep difficulties<\/li><li>hands or feet feel weak and numb, which can affect balance<\/li><li>changes in sensation, tingling, tickling, stinging, or burning sensation<\/li><li>taste changes<\/li><li>overindulge<\/li><li>eye inflammation (\u00a0conjunctivitis\u00a0), pain in the eyes, or vision problems<\/li><li>earache<\/li><li>low\u00a0blood pressure, which can make you feel dizzy or faint<\/li><li>trouble swallowing<\/li><li>constipation, flatulence, indigestion, stomach ache, swollen abdomen<\/li><li>mouth ulcers<\/li><li>abnormal results on liver and kidney tests<\/li><li>night sweats<\/li><li>itching, rash<\/li><li>hair loss<\/li><li>back pain, pain in muscles or joints, muscle cramps<\/li><li>feel dizzy, weak, or generally unwell<\/li><\/ul>\n\n\n\n<p><strong>Uncommon:<\/strong>&nbsp;may affect up to 1 in 100 patients<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>feel upset<\/li><li>tremors, tremors<\/li><li>deafness<\/li><li>irregular heartbeat<\/li><li>hives, dry skin<\/li><li>blood in the urine<\/li><li>infertility&nbsp;in men &#8211; see section &#8220;Pregnancy, breastfeeding and fertility&#8221;<\/li><li>chest pain<\/li><\/ul>\n\n\n\n<p>Separation of the inner part of the eye (retinal detachment) has only occurred in\u00a0AIDS\u00a0patients\u00a0treated with Valcyte for\u00a0CMV\u00a0infection.<\/p>\n\n\n\n<p><strong>Additional&nbsp;side effects&nbsp;in children and adolescents<\/strong><\/p>\n\n\n\n<p>Side effects&nbsp;reported&nbsp;in children and adolescents are similar to those&nbsp;reported in adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Valcyte<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date stated on the carton and label after Ex.&nbsp;dat.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Powder: No special storage instructions.<\/p>\n\n\n\n<p>Prepared solution: Store in a refrigerator (2\u00b0C-8\u00b0C).<\/p>\n\n\n\n<p>The shelf life of the oral solution is 49 days.&nbsp;Use the solution within 49 days after it is made (the pharmacy staff writes the date of preparation on the bottle).<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medications that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>The active substance is valganciclovir hydrochloride.\u00a0After the dissolution of the powder, 1 ml of solution contains 55 mg of valganciclovir hydrochloride equivalent to 50 mg of valganciclovir (as hydrochloride).<\/p>\n\n\n\n<p>Other ingredients (excipients) are Povidone, fumaric acid, sodium benzoate (E211), saccharin sodium and mannitol, tutti-frutti flavoring [maltodextrins (corn), propylene glycol, acacia gum E414 and nature-identical flavorings mainly consisting of banana, pineapple, and peach flavors].<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>The valcyte powder is a\u00a0granule\u00a0with a white to light yellow color.\u00a0The glass bottle contains 12 g of powder.\u00a0After\u00a0preparation, the amount of solution is 100 ml, which gives a usable volume of 88 ml.\u00a0The solution is clear and colorless to brown.\u00a0The package also contains a bottle adapter and 2 dosing syringes graduated up to 10 ml (500 mg) with graduations in 0.5 ml (25 mg) intervals.<\/p>\n\n\n\n<p>Package size: One bottle containing 12 g of powder.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Roche AB, Box 1228, 171 23 Solna<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Roche Pharma AG<\/p>\n\n\n\n<p>Emil-Barrell-Str.&nbsp;1<\/p>\n\n\n\n<p>79639 Grenzach-Wyhlen<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>Phone: (07624) 14-0<\/p>\n\n\n\n<p>Fax: (07624) 10 19<\/p>\n\n\n\n<p>Prestige Promotion Verkaufsfoerderung &amp; Werbeservice GmbH<\/p>\n\n\n\n<p>Lindigstrasse 6<\/p>\n\n\n\n<p>63801 Kleinostheim<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>Prestige Promotion Verkaufsfoerderung &amp; Werbeservice GmbH<\/p>\n\n\n\n<p>Borsigstrasse 2<\/p>\n\n\n\n<p>63755 Alzenau<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>This medicine is approved in the European Economic Area and the United Kingdom (Northern Ireland) under the names:<\/strong><\/p>\n\n\n\n<p><strong>Valcyte:<\/strong>&nbsp;Austria, Belgium, Croatia, Cyprus, Czech Republic, Denmark, Finland, Germany, Greece, Hungary, Iceland, Ireland, Italy, Lichtenstein, Lithuania, Luxembourg, Netherlands, Norway, Poland, Slovenia, Spain, Sweden, United Kingdom (Northern Ireland)<\/p>\n\n\n\n<p><strong>Valcyte:<\/strong>\u00a0France, Portugal<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Valcyte belongs to a group of drugs that act directly to prevent the multiplication of\u00a0viruses\u00a0.\u00a0The active ingredient in the powder, valganciclovir, is converted in the body to ganciclovir.\u00a0Ganciclovir prevents a\u00a0virus\u00a0called\u00a0cytomegalovirus\u00a0(\u00a0CMV\u00a0) from multiplying and attacking healthy cells.\u00a0In patients with a weakened immune system,\u00a0CMV\u00a0can cause\u00a0infection\u00a0in the body&#8217;s organs.\u00a0This can be life-threatening.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[26834,26829,26831,26833,26825,26828,26832,26826,26830,26827],"class_list":["post-26090","post","type-post","status-publish","format-standard","hentry","category-medicines","category-v","tag-benefits-of-valcyte","tag-benefits-of-valganciclovir","tag-valcyte","tag-valcyte-side-effects","tag-valganciclovir","tag-valganciclovir-side-effects","tag-what-is-valcyte","tag-what-is-valganciclovir","tag-what-valcyte-is-used-for","tag-what-valganciclovir-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26090","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=26090"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26090\/revisions"}],"predecessor-version":[{"id":26137,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26090\/revisions\/26137"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=26090"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=26090"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=26090"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}