{"id":26084,"date":"2022-10-11T12:28:09","date_gmt":"2022-10-11T12:28:09","guid":{"rendered":"https:\/\/zeepedia.com\/?p=26084"},"modified":"2022-10-12T11:23:07","modified_gmt":"2022-10-12T11:23:07","slug":"valaciclovir-mylan","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/valaciclovir-mylan\/","title":{"rendered":"Valaciclovir Mylan &#8211; Valaciclovir uses, dose and side effects"},"content":{"rendered":"\n<p>500 mg&nbsp;film-coated tablet<br>valaciclovir<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Valaciclovir Mylan is and what it is used for<\/h2>\n\n\n\n<p>Valaciclovir Mylan contains the active substance valaciclovir hydrochloride hydrate.&nbsp;Valaciclovir Mylan belongs to a group of medicines called antivirals.&nbsp;It works by killing or stopping the growth of&nbsp;viruses&nbsp;called&nbsp;herpes&nbsp;simplex (&nbsp;HSV&nbsp;),&nbsp;varicella zoster&nbsp;(&nbsp;VZV&nbsp;), and&nbsp;cytomegalovirus&nbsp;(&nbsp;CMV&nbsp;).<\/p>\n\n\n\n<p>Valaciclovir Mylan can be used to:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>treat&nbsp;shingles&nbsp;(in adults)<\/li><li>treat&nbsp;HSV&nbsp;skin infections and genital&nbsp;herpes&nbsp;(in adults and adolescents over 12 years of age).&nbsp;It is also used to help prevent these&nbsp;infections&nbsp;from coming back.<\/li><li>treat mouth ulcers (in adults and adolescents over 12 years of age)<\/li><li>prevent&nbsp;CMV&nbsp;&#8211;&nbsp;infection&nbsp;after organ transplantation (in adults and adolescents over 12 years)<\/li><li>treat and prevent&nbsp;recurrent HSV&nbsp;eye&nbsp;infections&nbsp;(in adults and adolescents over 12 years of age).<\/li><\/ul>\n\n\n\n<p>The valaciclovir contained in Valaciclovir Mylan may also be approved to treat other conditions not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Valaciclovir Mylan\u00a0<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Valaciclovir Mylan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to valaciclovir or aciclovir, or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have ever developed a widespread rash associated with fever, enlarged\u00a0lymph nodes, elevated levels of liver enzymes, and\/or\u00a0eosinophilia\u00a0(drug reaction with\u00a0eosinophilia\u00a0and systemic symptoms) after taking valaciclovir.<\/li><\/ul>\n\n\n\n<p>If you are not sure, talk to your doctor or pharmacist before taking Valaciclovir Mylan.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Valaciclovir Mylan:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have problems with your kidneys<\/li><li>if you have liver problems<\/li><li>if you are older than 65 years<\/li><li>if your immune system is weak.<\/li><\/ul>\n\n\n\n<p>Drug reaction with\u00a0eosinophilia\u00a0and systemic symptoms (DRESS) has been reported with the use of valaciclovir.\u00a0DRESS\u00a0initially\u00a0presents as\u00a0flu-like symptoms\u00a0and with a rash on the face, followed by widespread rash and high body temperature, increased levels of liver enzymes (found in blood tests), and an increase in a type of\u00a0white blood cell\u00a0(\u00a0eosinophilia\u00a0), and enlarged\u00a0lymph nodes.<\/p>\n\n\n\n<p>If you develop a rash associated with fever and enlarged\u00a0lymph nodes, stop taking valaciclovir and contact your doctor or seek medical attention immediately.<\/p>\n\n\n\n<p>If you are not sure if the above applies to you, talk to your doctor or pharmacist before taking Valaciclovir Mylan.<\/p>\n\n\n\n<p><strong>Prevent transmission of genital&nbsp;herpes&nbsp;to others<\/strong><\/p>\n\n\n\n<p>If you are taking Valaciclovir Mylan to treat genital\u00a0herpes, or if you have previously had genital\u00a0herpes, you should still practice safe sex, which means using a condom.\u00a0It is important to prevent you from infecting others.\u00a0You should not have sex if you have genital sores or blisters.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children under 12 years of age<\/h2>\n\n\n\n<p>This medicine is not recommended for children under 12 years of age.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Valaciclovir Mylan<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might be taking other medicines, including over-the-counter medicines, herbal medicines, or other natural products.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking other medicines that affect the kidneys.\u00a0These include\u00a0aminoglycoside, organoplatinum compounds, iodinated contrast agents, methotrexate, pentamidine, foscarnet, cyclosporine, tacrolimus, cimetidine, and probenecid.<\/p>\n\n\n\n<p>Always tell your doctor or pharmacist if you are taking other medicines while taking Valaciclovir Mylan to treat&nbsp;shingles&nbsp;or after an organ transplant.&nbsp;<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Valaciclovir Mylan is not normally recommended for use during pregnancy.\u00a0If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, consult your doctor before using this medicine.\u00a0Your doctor will then consider the benefit to you against the risk to your baby of taking Valaciclovir Mylan while you are pregnant or breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Valaciclovir can have&nbsp;side effects&nbsp;that can affect your ability to drive.<\/p>\n\n\n\n<p>Avoid driving or operating machinery unless you are sure you are unaffected.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure<strong>.<\/strong><br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Valaciclovir Mylan\u00a0<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The doctor determines the&nbsp;dose&nbsp;according to the reason for your treatment.&nbsp;Your doctor should discuss this with you.<\/p>\n\n\n\n<p><strong>Treatment of&nbsp;shingles<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;is 1000 mg (two 500 mg tablets) three times daily.<\/li><li>You must take Valaciclovir Mylan for seven days.<\/li><\/ul>\n\n\n\n<p><strong>Treatment of mouth ulcers<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended\u00a0dose\u00a0is 2000 mg (four 500 mg tablets) twice daily.<\/li><li>The second\u00a0dose\u00a0should be taken 12 hours (not earlier than 6 hours) after the first\u00a0dose.<\/li><li>You must take Valaciclovir Mylan for only one day (two\u00a0doses\u00a0).<\/li><\/ul>\n\n\n\n<p><strong>Treatment of&nbsp;HSV&nbsp;skin infections or genital&nbsp;herpes<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended\u00a0dose\u00a0is 500 mg (one 500 mg tablet) twice daily.<\/li><li>For the first infection, you must take Valaciclovir Mylan for five days, or up to ten days, if your doctor has prescribed this.\u00a0In case of recurrent\u00a0infection, the treatment period is normally 3-5 days.<\/li><\/ul>\n\n\n\n<p><strong>Help prevent&nbsp;HSV&nbsp;infection&nbsp;from&nbsp;returning after you&#8217;ve had them<\/strong><\/p>\n\n\n\n<p>\u2022 The recommended&nbsp;dose&nbsp;is one 500 mg tablet once daily.<\/p>\n\n\n\n<p>\u2022 Some people with frequent recurrent&nbsp;infections&nbsp;may benefit from taking one 250 mg tablet twice daily.&nbsp;For&nbsp;doses&nbsp;lower than 500 mg, Valaciclovir Mylan is not suitable.&nbsp;Lower strengths of other valaciclovir drugs are available.&nbsp;Your doctor will advise you on this.<\/p>\n\n\n\n<p>\u2022 You should take Valaciclovir Mylan until your doctor tells you to stop.<\/p>\n\n\n\n<p><strong>To prevent you from becoming infected with&nbsp;CMV&nbsp;(&nbsp;Cytomegalovirus&nbsp;)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended\u00a0dose\u00a0is 2000 mg (four tablets of 500 mg) four times daily.<\/li><li>You should have an interval of 6 hours between each\u00a0dose.<\/li><li>You should take Valaciclovir Mylan as soon as possible after your operation.<\/li><li>You should take Valaciclovir Mylan for about 3 months after your operation until your doctor prescribes you stop.<\/li><\/ul>\n\n\n\n<p><em><strong>Use for children under 12 years of age<\/strong><\/em><\/p>\n\n\n\n<p>Valaciclovir is not recommended for children under 12 years of age due to insufficient data regarding safety and efficacy.<\/p>\n\n\n\n<p><strong>Your doctor may adjust your&nbsp;dose&nbsp;of Valaciclovir Mylan:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are older than 65 years<\/li><li>if you have a weak immune system<\/li><li>if you have kidney problems.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor before taking Valaciclovir Mylan if any of the above applies to you.<\/p>\n\n\n\n<p><strong>How to take the medicine<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Take this medicine by mouth.<\/li><li>Swallow the tablets whole with water.<\/li><li>Take Valaciclovir Mylan at the same time each day.<\/li><li>Take Valaciclovir Mylan as directed by your doctor or pharmacist.<\/li><\/ul>\n\n\n\n<p><strong>Elderly people who are over 65 or have kidney problems.<\/strong><\/p>\n\n\n\n<p><strong>While you are taking\u00a0<\/strong><strong>Valaciclovir Mylan<\/strong>, you must drink water regularly\u00a0throughout the day.\u00a0This can help reduce the\u00a0side effects\u00a0that can affect the kidneys or nervous system.\u00a0Your doctor will check if you show any signs of this.\u00a0Side effects\u00a0from the nervous system can be that you feel confused, agitated, unusually sleepy, or drowsy.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Valaciclovir Mylan<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<p>Valaciclovir Mylan is usually not harmful unless you use too much for several days in a row.\u00a0If you take too many tablets, you may feel sick, vomit, become confused, agitated, or unusually sleepy.\u00a0You may see, feel or hear things that are not there (hallucinations), have kidney problems that manifest as urinating little or no urine or lose consciousness (\u00a0coma\u00a0).\u00a0Talk to your doctor or pharmacist if you have taken too much Valaciclovir Mylan.\u00a0Take the medicine package with you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Valaciclovir Mylan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take Valaciclovir Mylan, take it as soon as you remember.\u00a0However, if it is almost time for the next\u00a0dose, skip the missed\u00a0dose.<\/li><li>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Valaciclovir Mylan<\/h2>\n\n\n\n<p>Do not stop taking this medicine without consulting your doctor.<\/p>\n\n\n\n<p><strong>If you have further questions about this medicine, contact your doctor or pharmacist.<\/strong><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Side effects&nbsp;usually occur at the beginning of treatment and become milder or disappear within a few weeks.&nbsp;Sometimes it is difficult to distinguish between the symptoms of the disease and a side effect.<\/p>\n\n\n\n<p><strong>Contact your doctor or go to the nearest hospital emergency department immediately if you think you have any of the following\u00a0side effects.\u00a0Stop taking this medicine.<\/strong><\/p>\n\n\n\n<p><em>Rare (affects up to 1 in 1,000 users)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>severe allergic reactions (\u00a0anaphylaxis\u00a0).\u00a0The rapid development of symptoms such as:<\/li><li>redness, itchy rash<\/li><li>swelling of the lips, face, neck, and throat, causing difficulty breathing (\u00a0angioedema\u00a0)<\/li><li>drop in blood pressure leading to collapse<\/li><li>kidney problems, which manifest themselves as urinating little or no urine\u00a0<\/li><li>seizures (convulsions)<\/li><li>altered brain function (\u00a0encephalopathy\u00a0)<\/li><li>unconsciousness (\u00a0coma\u00a0)<\/li><li>confused or disturbed thoughts<\/li><\/ul>\n\n\n\n<p><em>Has been reported (occurring in an unknown number of users)<\/em><\/p>\n\n\n\n<p>Drug reaction with\u00a0eosinophilia\u00a0and systemic symptoms, also known as DRESS or drug hypersensitivity syndrome, is characterized by widespread rash, high body temperature, elevated liver enzymes, blood abnormalities (\u00a0eosinophilia\u00a0), enlarged\u00a0lymph nodes, and possible involvement of other organs.\u00a0See also section 2.<\/p>\n\n\n\n<p><strong>Additional\u00a0side effects\u00a0are<\/strong><\/p>\n\n\n\n<p><em>Very common (affects more than 1 in 10 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache<\/li><\/ul>\n\n\n\n<p><em>Common (affects up to 1 in 10 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>nausea<\/li><li>dizziness<\/li><li>vomiting<\/li><li>diarrhea<\/li><li>skin reactions, including after exposure to sunlight&nbsp;<em>(&nbsp;photosensitivity&nbsp;)<\/em><\/li><li>rash.<\/li><\/ul>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>confusion<\/li><li>hallucinations (seeing or hearing things that aren&#8217;t there)<\/li><li>drowsiness<\/li><li>tremor\u00a0_<\/li><li>the feeling of outrage.<\/li><\/ul>\n\n\n\n<p>These\u00a0side effects\u00a0from the nervous system usually occur in people with kidney problems, in the elderly, or in organ transplant patients who take high\u00a0doses\u00a0of valaciclovir, ie 8 g or more per day.\u00a0It usually gets better when Valaciclovir Mylan is stopped or when the\u00a0dose\u00a0is reduced.<\/p>\n\n\n\n<p>Other less common side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>shortness of breath (&nbsp;dyspnea&nbsp;)<\/li><li>stomach upset<\/li><li>skin rash, sometimes itchy,&nbsp;hives&nbsp;(&nbsp;urticaria&nbsp;)<\/li><li>low back pain (kidney pain)<\/li><li>blood in the urine.<\/li><\/ul>\n\n\n\n<p>Less common&nbsp;side effects&nbsp;that can be detected in blood tests:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>decrease in the number of\u00a0white blood cells\u00a0(\u00a0leukopenia\u00a0)<\/li><li>decrease in the number of\u00a0platelets, which help the blood clot (\u00a0thrombocytopenia\u00a0)<\/li><li>increase in substances produced by the liver.<\/li><\/ul>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>unsteady gait or lack of coordination (\u00a0ataxia\u00a0)<\/li><li>slow and slurred speech (dysarthria)<\/li><\/ul>\n\n\n\n<p>These\u00a0side effects\u00a0from the nervous system usually occur in people with kidney problems, in the elderly, or in organ transplant patients who take high\u00a0doses\u00a0of valaciclovir, ie 8 g or more per day.\u00a0It usually gets better when Valaciclovir Mylan is stopped or when the\u00a0dose\u00a0is reduced.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Valaciclovir Mylan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Use before the expiry date which is stated on the carton after EXP.\u00a0The expiration date is the last day of the specified month.<\/li><li>The medicine does not require any special storage instructions.<\/li><li>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medications that are no longer used.\u00a0These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<p><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is valaciclovir hydrochloride hydrate.\u00a0Each tablet contains valaciclovir hydrochloride hydrate equivalent to 500 mg of valaciclovir.<\/li><li>Other ingredients in the tablet core are: microcrystalline cellulose, crospovidone, povidone, and magnesium stearate<\/li><li>Ingredients in the coating are: titanium dioxide (E171), macrogol 400, polysorbate 80 (E433), and hypromellose (E464)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Valaciclovir Mylan is a white to off-white, capsule-shaped, biconvex film-coated tablet.<\/p>\n\n\n\n<p>500 mg film-coated tablets are marked \u201cVC 500\u201d on one side and \u201cG\u201d on the other side<\/p>\n\n\n\n<p>Valaciclovir Mylan is available in blister packs of 10, 21, 24, 30, 42, 60, 90, 100, and 112.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder:<\/h2>\n\n\n\n<p>Mylan AB<\/p>\n\n\n\n<p>Box 23033<\/p>\n\n\n\n<p>104 35 Stockholm<\/p>\n\n\n\n<p>Phone: 08-555 227 50<\/p>\n\n\n\n<p>Fax: 08-555 227 51<\/p>\n\n\n\n<p>e-mail:&nbsp;<a href=\"http:\/\/inform@mylan.se\/\" target=\"_blank\" rel=\"noreferrer noopener\">inform@mylan.se<\/a><\/p>\n\n\n\n<p><strong>Manufacturer:<\/strong><\/p>\n\n\n\n<p>McDermott Laboratories Ltd T\/A Gerard Laboratories, 35\/36 Baldoyle Industrial Estate, Grange Road, Dublin 13, Ireland<\/p>\n\n\n\n<p>Mylan Hungary Kft, Mylan utca 1, Komarom 2900, Hungary<\/p>\n\n\n\n<p>Generics [UK] Ltd, Station Close, Potters Bar, Hertfordshire.&nbsp;EN6 1TL, United Kingdom<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Valaciclovir Mylan contains the active substance valaciclovir hydrochloride hydrate.\u00a0Valaciclovir Mylan belongs to a group of medicines called antivirals.\u00a0It works by killing or stopping the growth of\u00a0viruses\u00a0called\u00a0herpes\u00a0simplex (\u00a0HSV\u00a0),\u00a0varicella zoster\u00a0(\u00a0VZV\u00a0), and\u00a0cytomegalovirus\u00a0(\u00a0CMV\u00a0).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22502],"tags":[26835,26851,26854,26853,26839,26838,26836,26850,26837,26852],"class_list":["post-26084","post","type-post","status-publish","format-standard","hentry","category-medicines","category-v","tag-valaciclovir","tag-valaciclovir-mylan","tag-valaciclovir-mylan-side-effects","tag-valaciclovir-mylan-tablet","tag-valaciclovir-side-effects","tag-valaciclovir-tablet","tag-what-is-valaciclovir","tag-what-is-valaciclovir-mylan","tag-what-valaciclovir-is-used-for","tag-what-valaciclovir-mylan-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26084","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=26084"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26084\/revisions"}],"predecessor-version":[{"id":26140,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26084\/revisions\/26140"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=26084"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=26084"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=26084"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}