{"id":26038,"date":"2022-10-10T14:15:50","date_gmt":"2022-10-10T14:15:50","guid":{"rendered":"https:\/\/zeepedia.com\/?p=26038"},"modified":"2023-01-12T13:52:18","modified_gmt":"2023-01-12T13:52:18","slug":"ursogrix","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/ursogrix\/","title":{"rendered":"Ursogrix &#8211; Ursodeoxycholic Acid Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Ursogrix 250 mg&nbsp;ursodeoxycholic acid hard capsules<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Ursogrix Is \u200b\u200bAnd What It Is Used For<\/h2>\n\n\n\n<p>This medicine contains ursodeoxycholic acid, which is a naturally occurring bile acid.\u00a0It is only found in small amounts in the bile of humans.<\/p>\n\n\n\n<p><strong>Ursogrix is \u200b\u200bused:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>To dissolve\u00a0gallstones\u00a0made up of\u00a0cholesterol\u00a0in patients<ul><li>Who have one or more\u00a0gallstones\u00a0that are invisible on X-ray, preferably with a diameter not exceeding 2 cm, in a normally functioning gallbladder<\/li><li>Who cannot undergo\u00a0surgery<\/li><li>Which supersaturation of\u00a0cholesterol\u00a0and chemical tests have demonstrated this on bile?<\/li><li>Before and after lithotripsy (crushing of\u00a0gallstones\u00a0with shock wave treatment).<\/li><\/ul><\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>For the treatment of conditions where the bile ducts in the liver have been damaged, leading to the accumulation of bile.&nbsp;This can cause scarring of the liver.&nbsp;The liver damage must not be so severe that the liver does not function normally.&nbsp;This condition is called primary biliary cholangitis (PBC, also called primary&nbsp;biliary cirrhosis&nbsp;).<\/li><li>For the treatment of liver disease associated with&nbsp;cystic fibrosis&nbsp;(<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cystic-fibrosis\/\">cystic fibrosis<\/a>) in children and adolescents between 6 and 18 years of age<\/li><\/ul>\n\n\n\n<p>Ursodeoxycholic acid found in Ursogrix tablets may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What You Need To Know Before You Use Ursogrix<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Use Ursogrix Tablets<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to ursodeoxycholic acid, bile acids, or any of the other ingredients of this medicine (listed in section 6)<\/li><li>If you have\u00a0acute\u00a0inflammation\u00a0of the gallbladder or bile ducts<\/li><li>If you have blocked bile ducts (blockage in the common bile duct or gallbladder duct)<\/li><li>If you often have cramp-like <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a> in the upper part of the abdomen (biliary colic)<\/li><li>If the doctor has said that you have\u00a0calcified\u00a0gallstones<\/li><li>If your gallbladder has reduced ability to contract<\/li><li>If your child has blocked bile ducts (bile duct atresia) and has poor bile flow, even after\u00a0surgery.<\/li><\/ul>\n\n\n\n<p>Ask your doctor about the conditions mentioned above.\u00a0Also, ask your doctor if you have previously had any of these conditions or are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Precautions<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Talk to your doctor or pharmacist before taking Ursogrix.\u00a0This medicine should only be used under medical supervision.<\/li><li>During the first 3 months of treatment, the function of your liver will be tested regularly every four weeks.\u00a0After that, tests will be conducted at 3-month intervals.<\/li><li>In treatment to dissolve\u00a0gallstones, the gallbladder will be checked after 6 to 10 months of treatment.<\/li><li>Women taking this medicine to dissolve\u00a0gallstones\u00a0should use effective, non-hormonal contraceptives because hormonal contraceptives (\u00a0birth control pills\u00a0) can increase the formation of\u00a0gallstones.<\/li><li>When treating the liver disease PBC, the symptoms (e.g.\u00a0itching\u00a0) may, in rare cases, increase at the beginning of the treatment.\u00a0If this occurs, tell your doctor.\u00a0The starting dose may need to be reduced.<\/li><li>If you get <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/diarrhea-in-children\/\">diarrhea<\/a>, you must tell your doctor.\u00a0The dose\u00a0may need to be reduced, or treatment with Ursogrix should be discontinued.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>There are no restrictions on using Ursogrix 250 mg hard capsules except in\u00a0cystic fibrosis\u00a0(aged 6\u201318 years).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Ursogrix<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>The effect of this medicine can be affected (&nbsp;interaction&nbsp;er):<\/p>\n\n\n\n<p>Ursogrix may have&nbsp;<strong>a reduced effect<\/strong>&nbsp;if it is used at the same time as the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cholestyramine, colestipol (for high blood fats), or antacids (<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/heartburn-gastric-reflux\/\">heartburn<\/a> medicines) containing aluminum hydroxide or smectite (aluminum oxide).\u00a0If you are taking a medicine containing any of these active substances, the medicine should be taken 2 hours before or after Ursogrix.<\/li><\/ul>\n\n\n\n<p>The following medicines may have\u00a0<strong>a reduced effect<\/strong>\u00a0if used simultaneously as Ursogrix.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Ciprofloxacin, dapsone (\u00a0antibiotic\u00a0), nitrendipine (for high\u00a0blood pressure\u00a0), and other similarly excreted drugs from the body.\u00a0The doctor may need to change the\u00a0dose\u00a0of these medicines.<\/li><\/ul>\n\n\n\n<p>The following medicines may have an\u00a0<strong>altered effect<\/strong>\u00a0if they are used simultaneously as Ursogrix.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Ciclosporin (to reduce the activity of the immune system).\u00a0If you are being treated with ciclosporin, your doctor will check the ciclosporin concentration in your blood.\u00a0The doctor adjusts the\u00a0dose\u00a0if necessary.<\/li><li>Rosuvastatin (against high blood fats).<\/li><\/ul>\n\n\n\n<p>If you are taking Ursogrix to dissolve\u00a0gallstones, tell your doctor if you are also taking medicines containing\u00a0estrogen\u00a0(e.g.\u00a0birth control pills\u00a0) or certain cholesterol-lowering medicines, e.g.\u00a0clofibrate.\u00a0These medicines can increase the formation of\u00a0gallstones\u00a0and thus counteract the dissolution of\u00a0gallstones\u00a0that Ursogrix does.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding, And Fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p><strong><em>Pregnancy<\/em><\/strong><\/p>\n\n\n\n<p>There is no or limited amount of data on the use of ursodeoxycholic acid in pregnant women.\u00a0It would be best if you did not take Ursogrix during pregnancy unless the doctor considers it necessary.\u00a0Based on animal studies, using ursodeoxycholic acid during pregnancy may affect fetal development.<\/p>\n\n\n\n<p><strong><em>Fertile women<\/em><\/strong><\/p>\n\n\n\n<p>Even if you are not pregnant, you should still discuss this with your doctor.\u00a0Fertile women (women who have the potential to become pregnant) should only be treated if they use a safe method of contraception.\u00a0Non-hormonal or oral contraceptives (\u00a0birth control pills\u00a0) with\u00a0low-dose\u00a0estrogen\u00a0are recommended.\u00a0If you are taking Ursogrix to dissolve\u00a0gallstones, you should use effective, non-hormonal contraception, as hormonal contraceptives can increase the formation of\u00a0gallstones.<\/p>\n\n\n\n<p>Before starting the treatment, the doctor will check that you are not pregnant.<\/p>\n\n\n\n<p><strong><em>Breast-feeding<\/em><\/strong><\/p>\n\n\n\n<p>There are only a few documented cases of using ursodeoxycholic acid during breastfeeding.\u00a0The levels of ursodeoxycholic acid in breast milk are very low.\u00a0Therefore, it is unlikely that this medicine would cause\u00a0side effects\u00a0in breastfed infants.<\/p>\n\n\n\n<p><strong><em>Fertility\/the ability to bear children<\/em><\/strong><\/p>\n\n\n\n<p>Animal studies have not shown any effect on fertility\/ability to give birth.<\/p>\n\n\n\n<p>So far, there is no information on the effects on&nbsp;human&nbsp;fertility<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving Ability And Use Of Machinery<\/h2>\n\n\n\n<p>No special precautions are necessary.<\/p>\n\n\n\n<p>You are responsible for assessing whether you can drive a motor vehicle or perform work requiring increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><br>How To Use Ursogrix<\/h2>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Ursogrix uses<\/span><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Always take this medicine as directed by your doctor.\u00a0Ask your doctor or pharmacist if you are unsure.<\/li><\/ul>\n\n\n\n<p><strong><em>For dissolution of cholesterol gallstones (without or with shock wave therapy)<\/em><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Dosage<\/strong><ul><li>The recommended\u00a0dose\u00a0is 2\u20134 capsules of Ursogrix (8\u201310 mg ursodeoxycholic acid\/kg body weight).<\/li><li>Does\u00a0one should be taken with a meal as follows:<ul><li>A daily\u00a0dose\u00a0of 2 capsules: both capsules are taken with food in the evening.<\/li><li>A daily\u00a0dose\u00a0of 3 capsules: 1 capsule in the morning and 2 in the evening.<\/li><li>A daily\u00a0dose\u00a0of 4 capsules: 2 in the morning and 2 in the evening.<\/li><\/ul><\/li><\/ul><\/li><\/ul>\n\n\n\n<p>OR<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Taken as a daily\u00a0dose\u00a0of 2\u20134 capsules in the evening before bedtime.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>How To Take Ursogrix<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Swallow the capsules whole with a glass of water or other liquid.\u00a0Take the capsules regularly.<\/li><li><strong>Treatment time<\/strong><ul><li>Gallstones\u00a0generally take 6\u201324 months to dissolve.\u00a0The treatment time depends on the size of the existing\u00a0gallstones\u00a0at the start of the treatment.\u00a0If the size of the\u00a0gallstones\u00a0has not decreased after 12 months, treatment should be discontinued.<\/li><li>At 6-month intervals, the doctor must check whether the treatment has any effect.\u00a0At each check-up, it must be followed up on whether calcification caused stone formation since the last time.\u00a0If this is the case, the doctor will stop the treatment.<\/li><li>Even if your symptoms have stopped, you should continue the treatment.\u00a0Interruption of the treatment leads to a longer total treatment time.\u00a0Treatment should continue for 3\u20134 months after the\u00a0gallstones\u00a0have dissolved.<\/li><\/ul><\/li><li><strong><em>For the treatment of primary biliary cholangitis (\u00a0chronic\u00a0inflammatory disease of the bile ducts)<\/em><\/strong><\/li><\/ul>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p><strong>Grades I\u2013III<\/strong><\/p>\n\n\n\n<p>The daily\u00a0dose\u00a0depends on body weight.\u00a0During the first three months after starting treatment, you must take Ursogrix in the morning, afternoon, and evening.\u00a0When liver function has improved, the daily\u00a0dose\u00a0can be taken once daily in the evening.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Body weight (kg)<\/td><td><strong>Ursogrix 250 mg hard capsules<\/strong><\/td><\/tr><tr><td><strong>Dosage&nbsp;during the first 3 months<\/strong><\/td><td><strong>Dosage&nbsp;after the first 3 months<\/strong><\/td><\/tr><tr><td>Morning<\/td><td>Afternoon<\/td><td>Evening<\/td><td>Evening(once daily)<\/td><\/tr><tr><td>47\u201362<\/td><td>1<\/td><td>1<\/td><td>1<\/td><td>3<\/td><\/tr><tr><td>63\u201378<\/td><td>1<\/td><td>1<\/td><td>2<\/td><td>4<\/td><\/tr><tr><td>79\u201393<\/td><td>1<\/td><td>2<\/td><td>2<\/td><td>5<\/td><\/tr><tr><td>94\u2013109<\/td><td>2<\/td><td>2<\/td><td>2<\/td><td>6<\/td><\/tr><tr><td>over 110<\/td><td>2<\/td><td>2<\/td><td>3<\/td><td>7<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Grade IV<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>At the beginning of the treatment, 2-3 Ursogrix capsules daily with a meal:<ul><li>A daily\u00a0dose\u00a0of 2 capsules: 1 capsule in the morning and 1 capsule in the evening. <\/li><li>A daily\u00a0dose\u00a0of 3 capsules: 1 capsule in the morning and 2 in the evening.<\/li><\/ul><\/li><li>If this\u00a0dosage\u00a0has a good effect (according to the blood test or the doctor&#8217;s judgment), the doctor will increase the\u00a0dose\u00a0one (\u00a0dosage\u00a0according to the treatment of grades I\u2013III).<\/li><li>Swallow the capsules whole with a glass of water or other liquid.\u00a0Take the capsules regularly.<\/li><li><strong>Treatment time<\/strong><ul><li>The use of Ursogrix in treating primary biliary cholangitis can be continued indefinitely.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>ATTENTION!<\/strong><\/p>\n\n\n\n<p>If you have primary biliary cholangitis, the symptoms, e.g.&nbsp;itching, increase at the beginning of the treatment.&nbsp;This happens only in rare cases.&nbsp;If this occurs, treatment can be continued with a reduced daily&nbsp;dose&nbsp;of Ursogrix.&nbsp;The doctor will increase the daily&nbsp;dose&nbsp;by one after each week until the desired&nbsp;dose&nbsp;is reached.<\/p>\n\n\n\n<p><strong><em>Use in children and adolescents (aged 6 to 18 years) for treating<\/em><\/strong> a <strong><em>liver disease associated with\u00a0cystic fibrosis.<\/em><\/strong><\/p>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p>The recommended daily&nbsp;dose&nbsp;is 20 mg\/kg body weight divided into 2\u20133&nbsp;doses.&nbsp;If necessary, the doctor can increase the&nbsp;dose&nbsp;to 30 mg\/kg body weight daily.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Body weight (kg)<\/td><td>Daily&nbsp;dose&nbsp;(mg\/kg body weight)<\/td><td><strong>Ursogrix 250 mg hard capsules<\/strong><\/td><\/tr><tr><td>Morning<\/td><td>Afternoon<\/td><td>Evening<\/td><\/tr><tr><td>20\u201329<\/td><td>17\u201325<\/td><td>1<\/td><td>&#8212;<\/td><td>1<\/td><\/tr><tr><td>30\u201339<\/td><td>19\u201325<\/td><td>1<\/td><td>1<\/td><td>1<\/td><\/tr><tr><td>40\u201349<\/td><td>20\u201325<\/td><td>1<\/td><td>1<\/td><td>2<\/td><\/tr><tr><td>50\u201359<\/td><td>21\u201325<\/td><td>1<\/td><td>2<\/td><td>2<\/td><\/tr><tr><td>60\u201369<\/td><td>22\u201325<\/td><td>2<\/td><td>2<\/td><td>2<\/td><\/tr><tr><td>70\u201379<\/td><td>22\u201325<\/td><td>2<\/td><td>2<\/td><td>3<\/td><\/tr><tr><td>80\u201389<\/td><td>22\u201325<\/td><td>2<\/td><td>3<\/td><td>3<\/td><\/tr><tr><td>90\u201399<\/td><td>23\u201325<\/td><td>3<\/td><td>3<\/td><td>3<\/td><\/tr><tr><td>100\u2013109<\/td><td>23\u201325<\/td><td>3<\/td><td>3<\/td><td>4<\/td><\/tr><tr><td>&gt; 110<\/td><td><\/td><td>3<\/td><td>4<\/td><td>4<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>How to take<\/strong>:<\/p>\n\n\n\n<p>Swallow the capsules whole with a glass of water or other liquid.&nbsp;Take the capsules regularly.<\/p>\n\n\n\n<p>If you have trouble swallowing or weigh less than 47 kg, other pharmaceutical forms of ursodeoxycholic acid are available.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you think Ursogrix has too strong or too weak an effect.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Use Too Much Ursogrix \u00a0<\/h2>\n\n\n\n<p>If you have ingested too much medicine or, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<p><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/stomach-disease-diarrhea-and-vomiting\/\">Diarrhea<\/a> may occur in case of overdose.\u00a0Tell your doctor immediately if you have persistent diarrhea.\u00a0If you have diarrhea, drink enough to restore fluid and salt balance.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Use Ursogrix<\/h2>\n\n\n\n<p>Do not take more capsules the next time, but continue the treatment with the prescribed&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Stop Using Ursogrix<\/h2>\n\n\n\n<p>Always talk to your doctor before stopping treatment with Ursogrix or if you intend to stop treatment early. If you have any further questions about this medicine, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible Ursogrix Side Effects<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them.<\/p>\n\n\n\n<p><em>Common<\/em>&nbsp;(may affect up to 1 in 10 patients):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Soft, loose stools or diarrhea.<\/li><\/ul>\n\n\n\n<p><em>Very rare<\/em>\u00a0Ursogrix side effects(may affect up to 1 in 10,000 patients):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>In the treatment of primary biliary cholangitis:<ul><li>Severe pain in the upper right part of the stomach, severe scarring of the liver that partially resolves after treatment ends<\/li><\/ul><\/li><li>Calcification of\u00a0gallstones\u00a0ar<\/li><li>Hives<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How To Store Ursogrix<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Store at a maximum of 30 \u00b0C.<\/li><li>Store in the original packaging.\u00a0Moisture sensitive.<\/li><li>Keep this medicine out of sight and reach of children.<\/li><li>Use before the expiry date, which is stated on the carton after EXP.\u00a0The expiration date is the last day of the specified month.<\/li><\/ul>\n\n\n\n<p>Medicines must not be thrown into the drain or among household waste.\u00a0Ask the pharmacist how to dispose of medications that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is ursodeoxycholic acid.<\/li><li>Each hard capsule contains 250 mg of ursodeoxycholic acid.<\/li><li>Other ingredients are corn starch, silicon dioxide (E 551), magnesium stearate (E 470B), hard gelatin capsule (capsule shell): titanium dioxide (E 171), and gelatin (E 441).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">AppearanceAand Package Sizes Of The Medicine<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>White, hard gelatin capsule containing white or almost white powder.\u00a0Capsule size 0, approximately 21.7mm x 7.64mm.<\/li><li>The capsules are packed in PVC\/aluminum blisters.<\/li><li>10 capsules per blister.<\/li><li>5, 6, or 10 blisters (50, 60, or 100 capsules) are packed in a carton.<\/li><li>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>AS GRINDEKS.&nbsp;Krustpils iela 53, R\u012bga, LV-1057, Latvia<\/p>\n\n\n\n<p><strong>Local Representative<\/strong><\/p>\n\n\n\n<p>2care4 Generics ApS<\/p>\n\n\n\n<p>Stenhuggervej 12-14<\/p>\n\n\n\n<p>DK-6710 Esbjerg V<\/p>\n\n\n\n<p>Denmark<\/p>\n\n\n\n<p><strong>This medicine is approved in the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Austria<\/td><td>Ursogrix 250 mgThe resin capsule<\/td><\/tr><tr><td>Belgium<\/td><td>URSOGRIX 250 mg hard capsules<\/td><\/tr><tr><td>Bulgaria<\/td><td>Ursogrix250 mg hard capsules\u0423\u0440\u0441\u043e\u0433\u0440\u0438\u043a\u0441 250 mg solidcapsule<\/td><\/tr><tr><td><br>Czech Republic<\/td><td>URSOGRIX<\/td><\/tr><tr><td>Croatia<\/td><td>URSOGRIX 250 mg hard capsule<\/td><\/tr><tr><td>Denmark<\/td><td>Ursogrix<\/td><\/tr><tr><td>Estonia<\/td><td>URSOGRIX<\/td><\/tr><tr><td>France<\/td><td>ACIDE URSODESOXYCHOLIQUE GRINDEKS 250 mg, gelule<\/td><\/tr><tr><td>Germany<\/td><td>Ursogrix 250 mg hard capsule<\/td><\/tr><tr><td>Greece<\/td><td>Ursogrix 250 mg \u03a3\u03ba\u03bb\u03b7\u03c1\u03ac \u03ba\u03b1\u03c8\u03ac\u03ba\u03b9\u03b1<\/td><\/tr><tr><td>Hungary<\/td><td>Urzodezoxikol sap Grindeks250 mg hard capsule<\/td><\/tr><tr><td>Ireland<\/td><td>Ursogrix 250 mg hard capsules<\/td><\/tr><tr><td>Latvia<\/td><td>URSOGRIX 250 mg ciet\u0101s kapsulas<\/td><\/tr><tr><td>Lithuania<\/td><td>URSOGRIX 250 mg kietosios kapsul\u0117s<\/td><\/tr><tr><td>Netherlands<\/td><td>GRINTEROL 250 mg hard capsules<\/td><\/tr><tr><td>Norway<\/td><td>URSOGRIX 250 mg hard capsules<\/td><\/tr><tr><td>Poland<\/td><td>URSOXYN<\/td><\/tr><tr><td>Portugal<\/td><td>GRINTEROL 250 mg capsules duras<\/td><\/tr><tr><td>Romania<\/td><td>Ursogrix 250 mg capsule<\/td><\/tr><tr><td>Slovakia<\/td><td>Ursogrix 250 mg hard capsules<\/td><\/tr><tr><td>Spain<\/td><td>\u00c1cido Ursodesoxic\u00f3lico Grindeks250 mg capsules duras<\/td><\/tr><tr><td>Sweden<\/td><td>Ursogrix 250 mg hard capsules<\/td><\/tr><tr><td>UK<\/td><td>Ursodeoxycholic Acid 250 mg Capsules, hard<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Whether you are taking Ursogrix to dissolve gallstones, let your doctor know if you are also taking oestrogen-containing medications that decrease cholesterol, such as clofibrate<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22501],"tags":[26812,26803,26807,26806,26809,26811,26804,26808,26805,26810],"class_list":["post-26038","post","type-post","status-publish","format-standard","hentry","category-medicines","category-u","tag-benefits-of-ursogrix","tag-ursodeoxycholic-acid","tag-ursodeoxycholic-acid-benefits","tag-ursodeoxycholic-acid-side-effects","tag-ursogrix","tag-ursogrix-side-effects","tag-what-is-ursodeoxycholic-acid","tag-what-is-ursogrix","tag-what-ursodeoxycholic-acid-is-used-for","tag-what-ursogrix-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26038","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=26038"}],"version-history":[{"count":40,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26038\/revisions"}],"predecessor-version":[{"id":44536,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26038\/revisions\/44536"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=26038"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=26038"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=26038"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}