{"id":26036,"date":"2022-10-10T14:14:26","date_gmt":"2022-10-10T14:14:26","guid":{"rendered":"https:\/\/zeepedia.com\/?p=26036"},"modified":"2022-10-11T08:16:08","modified_gmt":"2022-10-11T08:16:08","slug":"ursofalcon","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/ursofalcon\/","title":{"rendered":"Ursofalcon &#8211; Ursodeoxycholic acid uses, dose and side effects"},"content":{"rendered":"\n<p>500 mg&nbsp;film-coated tablets<br>ursodeoxycholic acid<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Ursofalk is and what it is used for<\/h2>\n\n\n\n<p>Ursofalk contains the active substance ursodeoxycholic acid, which is a naturally occurring bile acid found in small amounts in human bile.<\/p>\n\n\n\n<p>Ursofalk is used to dissolve small&nbsp;gallstones&nbsp;and in liver disease (primary&nbsp;biliary cirrhosis&nbsp;) to stimulate bile flow, among other things.<\/p>\n\n\n\n<p>Ursofalk is also used for a liver disease associated with a condition called&nbsp;cystic fibrosis&nbsp;(also called cystic fibrosis) in children aged 6 to 18 years.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Ursofalk<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Ursofalk<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to ursodeoxycholic acid or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have\u00a0acute\u00a0inflammation\u00a0of the gallbladder or bile ducts<\/li><li>if you have a blockage in the common bile duct or bile ducts.<\/li><li>if you often have biliary colic (cramp-like pain in the upper abdomen)<\/li><li>if your doctor has told you that you have\u00a0calcified\u00a0gallstones<\/li><li>if you have impaired gallbladder function<\/li><li>if your child has bile duct atresia (a rare disease in which the bile ducts outside the liver do not work) and has poor bile flow, even after\u00a0surgery.<\/li><\/ul>\n\n\n\n<p>Ask your doctor about the conditions mentioned above.\u00a0Also, ask your doctor if you have previously had any of these conditions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>During the first three months of treatment, the function of your liver will be tested to see how the treatment is working and to detect&nbsp;side effects&nbsp;in the liver.<\/p>\n\n\n\n<p>When treating to dissolve\u00a0gallstones, tests will be carried out after 6 to 10 months of treatment to check if the treatment is successful.<\/p>\n\n\n\n<p>Women taking Ursofalk for the dissolution of\u00a0gallstones\u00a0should only use non-hormonal contraceptives as hormonal contraceptives can increase the formation of\u00a0gallstones\u00a0(see also section pregnancy, breastfeeding, and\u00a0fertility\u00a0below).<\/p>\n\n\n\n<p>When treating the liver disease primary\u00a0biliary cirrhosis, in rare cases certain symptoms (e.g.\u00a0itching\u00a0) may worsen at the beginning of treatment.\u00a0If this occurs, talk to your doctor.\u00a0The treatment can be continued with a lower daily\u00a0dose.\u00a0Each week your doctor will then gradually increase the daily\u00a0dose\u00a0by one to the recommended daily\u00a0dose.<\/p>\n\n\n\n<p>If you get diarrhea, you must tell your doctor, your\u00a0dose\u00a0of Ursofalk may need to be changed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Ursofalk<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0It is especially important if you are taking the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>colestipol and cholestyramine (for high blood lipids)<\/li><li>antacids (against a sour stomach) containing aluminum hydroxide or aluminum oxide.<\/li><li>ciclosporin (to reduce the effect on the immune system during transplants)<\/li><li>ciprofloxacin\u00a0(for\u00a0infection\u00a0)<\/li><li>nitrendipine (for high\u00a0blood pressure\u00a0)<\/li><li>dapsone (for\u00a0HIV\u00a0)<\/li><li>estrogenic\u00a0hormones\u00a0(found in some\u00a0birth control pills\u00a0and medicines for menopause)<\/li><li>clofibrate (for high blood lipids)<\/li><li>rosuvastatin (for high blood lipids)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p>It is unknown whether Ursofalk affects the fetus or passes into breast milk.\u00a0Ursofalk should not be used during pregnancy or breastfeeding unless necessary.<\/p>\n\n\n\n<p>Before you start treatment with Ursofalk, a check must be made to rule out that you are pregnant.<\/p>\n\n\n\n<p><em>Women of&nbsp;childbearing&nbsp;age<\/em><\/p>\n\n\n\n<p>Women of\u00a0childbearing\u00a0age should only be treated with Ursofalk if contraception is used at the same time.\u00a0Non-hormonal contraceptives or\u00a0birth control pills\u00a0with\u00a0low-dose\u00a0estrogen\u00a0are recommended.<\/p>\n\n\n\n<p>If you take Ursofalk to dissolve\u00a0gallstones, only non-hormonal contraceptives should be used, as hormonal contraceptives can increase the formation of\u00a0gallstones.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Ursofalk has no or negligible effect on the ability to drive and use machines.<a><\/a><br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Ursofalk<\/h2>\n\n\n\n<p>Always use Ursofalk according to your doctor&#8217;s instructions.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><em>Dissolving gallstones:<\/em><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;for adults is 10-12 mg\/kg body weight daily, divided into 2 dosing occasions.<\/p>\n\n\n\n<p>It generally takes 6-24 months for&nbsp;gallstones&nbsp;to dissolve.&nbsp;If the size of the&nbsp;gallstones&nbsp;does not decrease after 12 months, treatment should be discontinued.<\/p>\n\n\n\n<p><em>Primary biliary cirrhosis:<\/em>&nbsp;Usual&nbsp;dose&nbsp;for adults is 12-16 mg\/kg body weight daily.<\/p>\n\n\n\n<p>During the first 3 months after starting treatment, Ursofalk tablets should be taken spread out over the day.&nbsp;When the liver values \u200b\u200bhave improved,&nbsp;dose&nbsp;one can be taken once a day, preferably in the evening.<\/p>\n\n\n\n<p>The use of Ursofalk in the treatment of primary biliary&nbsp;cirrhosis&nbsp;can be continued indefinitely.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use in children (6 years up to 18 years) for the treatment of a liver disease associated with cystic fibrosis<\/h2>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p>The recommended daily\u00a0dose\u00a0is 20 mg per kg of body weight, divided into 2-3\u00a0doses.\u00a0Your doctor may wish to increase the\u00a0dose\u00a0further to 30 mg per kg of body weight per day if necessary.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Body weight(kg)<\/td><td>Daily&nbsp;dose(mg\/kg body weight)<\/td><td>Ursofalk 500 mg film-coated tablet<\/td><\/tr><tr><td>Morning<\/td><td>Dinner<\/td><td>Evening<\/td><\/tr><tr><td>20 \u2013 29<\/td><td>17-25<\/td><td>\u00bd<\/td><td>&#8211;<\/td><td>\u00bd<\/td><\/tr><tr><td>30 \u2013 39<\/td><td>19-25<\/td><td>\u00bd<\/td><td>\u00bd<\/td><td>\u00bd<\/td><\/tr><tr><td>40 \u2013 49<\/td><td>20-25<\/td><td>\u00bd<\/td><td>\u00bd<\/td><td>1<\/td><\/tr><tr><td>50 \u2013 59<\/td><td>21-25<\/td><td>\u00bd<\/td><td>1<\/td><td>1<\/td><\/tr><tr><td>60 \u2013 69<\/td><td>22-25<\/td><td>1<\/td><td>1<\/td><td>1<\/td><\/tr><tr><td>70 \u2013 79<\/td><td>22-25<\/td><td>1<\/td><td>1<\/td><td>1\u00bd<\/td><\/tr><tr><td>80 \u2013 89<\/td><td>22-25<\/td><td>1<\/td><td>1\u00bd<\/td><td>1\u00bd<\/td><\/tr><tr><td>90 \u2013 99<\/td><td>23-25<\/td><td>1\u00bd<\/td><td>1\u00bd<\/td><td>1\u00bd<\/td><\/tr><tr><td>100 \u2013 109<\/td><td>23-25<\/td><td>1\u00bd<\/td><td>1\u00bd<\/td><td>2<\/td><\/tr><tr><td>&gt;110<\/td><td>&#8211;<\/td><td>1\u00bd<\/td><td>2<\/td><td>2<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>How to take Ursofalk<\/strong><\/p>\n\n\n\n<p>The tablets can be divided into two equal parts.\u00a0When\u00a0dosing\u00a0with \u00bd tablet, the remaining part can be saved for the next\u00a0dose.<\/p>\n\n\n\n<p>Swallow the tablets without chewing or crushing them together with a glass of water or other liquid.\u00a0You must take the tablets regularly.<\/p>\n\n\n\n<p>If you weigh less than 47 kg or cannot swallow Ursofalk tablets, Ursofalk&nbsp;oral&nbsp;solution may be an alternative.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have used too much Ursofalk&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<p>In case of overdose, diarrhea may occur.&nbsp;Contact your doctor immediately if you have persistent diarrhea.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Ursofalk<\/h2>\n\n\n\n<p>Do not take double\u00a0doses\u00a0to make up for missed\u00a0doses.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Ursofalk<\/h2>\n\n\n\n<p>Always talk to your doctor before you stop taking Ursofalk.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people):<\/em>&nbsp;Diarrhoea, pale stools.<\/p>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 users):<\/em>\u00a0Severe pain in the upper right part of the stomach in the treatment of liver disease (primary\u00a0biliary cirrhosis\u00a0), deterioration of liver function in the treatment of liver disease (primary\u00a0biliary cirrhosis\u00a0) which may return to the normal at the end of treatment, calcium deposits in\u00a0gallstones\u00a0(shown by the test, you don&#8217;t get any further symptoms), hives.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How Ursofalk should be stored<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date stated on the packaging after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>The medicine must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to deal with drugs that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is ursodeoxycholic acid (UDCA).&nbsp;One film-coated tablet contains 500 mg of ursodeoxycholic acid.<\/li><li>Other ingredients are magnesium stearate, polysorbate 80, povidone K 25, microcrystalline cellulose,&nbsp;colloidal&nbsp;anhydrous silica, crospovidone (type A), talc, hypromellose and macrogol 6000.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>White, oval, biconvex tablet with a score on both sides.<\/p>\n\n\n\n<p>Packs of 50 and 100 film-coated tablets.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p>Dr. Falk Pharma GmbH<\/p>\n\n\n\n<p>Leinenweberstrasse.&nbsp;5<\/p>\n\n\n\n<p>79108 Freiburg<\/p>\n\n\n\n<p>Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ursofalk contains the active substance ursodeoxycholic acid, which is a naturally occurring bile acid found in small amounts in human bile.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22501],"tags":[26803,26806,26813,26814,26818,26817,26804,26815,26805,26816],"class_list":["post-26036","post","type-post","status-publish","format-standard","hentry","category-medicines","category-u","tag-ursodeoxycholic-acid","tag-ursodeoxycholic-acid-side-effects","tag-ursodeoxycholic-acid-tablet","tag-ursofalcon","tag-ursofalcon-side-effects","tag-ursofalcon-tablet","tag-what-is-ursodeoxycholic-acid","tag-what-is-ursofalcon","tag-what-ursodeoxycholic-acid-is-used-for","tag-what-ursofalcon-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26036","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=26036"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26036\/revisions"}],"predecessor-version":[{"id":26073,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/26036\/revisions\/26073"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=26036"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=26036"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=26036"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}