{"id":25935,"date":"2022-09-30T12:43:39","date_gmt":"2022-09-30T12:43:39","guid":{"rendered":"https:\/\/zeepedia.com\/?p=25935"},"modified":"2022-10-01T08:04:47","modified_gmt":"2022-10-01T08:04:47","slug":"typhim-vi","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/typhim-vi\/","title":{"rendered":"Typhim Vi uses, dose and side effects"},"content":{"rendered":"\n<p>25 micrograms\/0.5 ml solution for injection in a pre-filled syringe<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Typhim Vi is and what it is used for<\/h2>\n\n\n\n<p>Typhim Vi is a vaccine used to protect against&nbsp;typhoid fever&nbsp;.<\/p>\n\n\n\n<p>Typhim Vi is used to vaccinate people traveling to areas where there is a high risk of contracting&nbsp;typhoid fever&nbsp;caused by&nbsp;<em>Salmonella&nbsp;typhi<\/em>&nbsp;&nbsp;&#8211; bacteria.<\/p>\n\n\n\n<p>When vaccinated, the immune system (the body&#8217;s natural defense system) produces protection against&nbsp;typhoid fever&nbsp;.<\/p>\n\n\n\n<p><strong>Limitations in the vaccine&#8217;s protection<\/strong><\/p>\n\n\n\n<p>Please note that Typhim Vi only protects against this disease if it has been caused by the same&nbsp;bacteria&nbsp;that has been used to make the vaccine.&nbsp;You or your child can still get an infectious disease if it is caused by other bacteria.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Typhim Vi<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Typhim Vi<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you or your child are allergic to the active substance or any other ingredient in this vaccine (listed in section 6)<\/li><li>if you or your child has a high fever or an&nbsp;acute&nbsp;infection&nbsp;.&nbsp;Vaccination with Typhim We must be postponed until after you or your child has recovered.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist or nurse before you are vaccinated with Typhim Vi.<\/p>\n\n\n\n<p>Talk to your doctor before vaccination about:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you or your child is allergic (hypersensitive) to formaldehyde or casein.&nbsp;Formaldehyde and casein are used during the production of Typhim Vi and there may be traces of these substances in the vaccine.<\/li><li>you or your child have problems with the immune system or you or your child is receiving immunosuppressive treatment.&nbsp;It is recommended to postpone vaccination until such illness or treatment is over.&nbsp;It is recommended to give Typhim Vi to people who have&nbsp;chronic&nbsp;problems with their immune system&nbsp;(including&nbsp;HIV&nbsp;infection&nbsp;), but protection against&nbsp;infection&nbsp;after vaccination may not be as good in people with good immunity against&nbsp;infection&nbsp;.<\/li><li>you or your child have&nbsp;thrombocytopenia&nbsp;(reduced number of&nbsp;blood platelets&nbsp;) or a bleeding disorder as bleeding may occur at the injection site.<\/li><\/ul>\n\n\n\n<p>Fainting can occur (mainly in young people) after, or even before, a needle stick.&nbsp;Therefore, tell the doctor or nurse if your child has fainted during a previous&nbsp;injection&nbsp;.<\/p>\n\n\n\n<p><strong><em>Typhim We contain&nbsp;sodium<\/em><\/strong><\/p>\n\n\n\n<p>Typhim Vi contains less than 1 mmol (23 mg) of&nbsp;sodium per&nbsp;dose&nbsp;, i.e. is almost &#8216;sodium-free&#8217;.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Typhim Vi<\/h2>\n\n\n\n<p>Tell the doctor or pharmacist if you or your child are taking, have recently taken or might take other medicines or receive other vaccines.<\/p>\n\n\n\n<p>Typhim Vi can be given at the same time as other common vaccines such as vaccines against yellow fever,&nbsp;diphtheria&nbsp;, tetanus, poliomyelitis, rabies produced on vero cells,&nbsp;meningitis&nbsp;A+C,&nbsp;hepatitis&nbsp;A and B, if they are given in different parts of the body (e.g. the other arm or the leg).<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this vaccine.<\/p>\n\n\n\n<p>Typhim Vi should only be used by pregnant women when absolutely necessary, and after the risks to the fetus have been weighed against the benefits to the mother.<\/p>\n\n\n\n<p>As it is not known whether the vaccine is excreted in human milk, caution should be exercised when Typhim Vi is administered to lactating women.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>No known risks.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Typhim We contain polysaccharide vaccine against typhoid fever<\/h2>\n\n\n\n<p><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Typhim Vi<\/h2>\n\n\n\n<p><strong>Dosage&nbsp;<em>:<\/em><\/strong><\/p>\n\n\n\n<p><strong>Adults and children from 2 years of age<\/strong>&nbsp;receive a&nbsp;dose&nbsp;of 0.5 ml.<\/p>\n\n\n\n<p>Children under 2 years of age: As with other polysaccharide vaccines, the antibody response may be insufficient in children under 2 years of age.<\/p>\n\n\n\n<p>Vaccination should be done at least two weeks before potential exposure to&nbsp;<em>Salmonella typhi&nbsp;<\/em><em>.<\/em><\/p>\n\n\n\n<p>Renewed vaccination is recommended after 3 years if there is a risk of exposure to infection.<\/p>\n\n\n\n<p><strong>Method of administration and route of administration<\/strong><\/p>\n\n\n\n<p>Typhim Vi is given as an&nbsp;injection&nbsp;into a muscle or deep under the skin.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this vaccine can cause&nbsp;side effects&nbsp;, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Serious allergic reactions:<\/strong><\/p>\n\n\n\n<p>Anaphylactic and anaphylactoid reactions, including anaphylactic&nbsp;shock&nbsp;, which may be associated with one or more of the following symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>hives&nbsp;, skin rash<\/li><li>swelling of the face or neck<\/li><li>difficulty breathing, bluish tongue or bluish lips<\/li><li>low&nbsp;blood pressure&nbsp;, rapid heartbeat and weak&nbsp;pulse&nbsp;, cold skin, dizziness and possible fainting.<\/li><\/ul>\n\n\n\n<p>When such signs or symptoms occur, it is usually very soon after an&nbsp;injection&nbsp;is given, while the person is still in the clinic or doctor&#8217;s office.&nbsp;If you observe any of these symptoms after leaving the clinic or reception where an&nbsp;injection&nbsp;was given, you must contact a doctor IMMEDIATELY.<\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;ar<\/strong><\/p>\n\n\n\n<p>Most&nbsp;side effects&nbsp;occur within 3 days after the vaccination.&nbsp;Most&nbsp;side effects&nbsp;disappear by themselves within 1\u20133 days after they appear.&nbsp;Side effects&nbsp;have been reported with the following frequency of occurrence (&nbsp;side effects&nbsp;apply to both adults and children from the age of 2 with some exceptions, see footnotes):<\/p>\n\n\n\n<p><strong>Very common: may affect more than 1 in 10 users<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pain at the injection site,&nbsp;redness&nbsp;at the injection site&nbsp;<sup>1<\/sup>&nbsp;, swelling at the injection site&nbsp;<sup>1<\/sup>&nbsp;, induration at the injection site&nbsp;<sup>1<\/sup><\/li><li>Headache&nbsp;<sup>1<\/sup><\/li><li>Muscle pain<\/li><li>General malaise (nausea)&nbsp;<sup>2<\/sup><\/li><li>Fatigue&nbsp;<sup>2<\/sup>&nbsp;, abnormal weakness&nbsp;<sup>2<\/sup>&nbsp;.<\/li><\/ul>\n\n\n\n<p><strong>Common: may affect up to 1 in 10 users<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fever&nbsp;<sup>3<\/sup><\/li><\/ul>\n\n\n\n<p><strong>Uncommon: may affect up to 1 in 100 users<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Itching&nbsp;at the injection site&nbsp;<sup>4<\/sup><\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurring in an unknown number of users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Serum sickness: joint pain, skin rash, enlarged&nbsp;lymph nodes&nbsp;and general malaise.&nbsp;If these symptoms occur, this usually occurs within 2-4 weeks after vaccination.<\/li><li>Fainting as a result of&nbsp;injection&nbsp;(vasovagal syncope)<\/li><li>Cough, wheezing, difficulty breathing (&nbsp;asthma&nbsp;)<\/li><li>Nausea, vomiting, diarrhoea, stomach pain<\/li><li>Skin rash, sometimes with swelling and&nbsp;itching&nbsp;(&nbsp;pruritus&nbsp;, rash,&nbsp;hives&nbsp;)<\/li><li>Joint pain.<\/li><\/ul>\n\n\n\n<p>1) common&nbsp;side effects&nbsp;in adults<\/p>\n\n\n\n<p>2) common&nbsp;side effects&nbsp;in children and adolescents (2\u201317 years of age)<\/p>\n\n\n\n<p>3) has not been reported in adults<\/p>\n\n\n\n<p>4) has not been reported in children and adolescents (2\u201317 years of age).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How Typhim Vi should be stored<\/h2>\n\n\n\n<p>Store out of sight and reach of children.<\/p>\n\n\n\n<p>Store in a refrigerator (2 \u00b0C\u20138 \u00b0C).&nbsp;Do not freeze.&nbsp;Store the syringe in the outer carton.&nbsp;Light sensitive.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton and on the syringe label after EXP.<\/p>\n\n\n\n<p>The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>The medicine must not be thrown into the drain or among household waste.&nbsp;Ask the pharmacist how to deal with medicines that are no longer used.&nbsp;These measures will help to protect the environment.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is purified Vi capsular polysaccharide of&nbsp;<em>Salmonella typhi<\/em>&nbsp;(Ty2 strain).&nbsp;Each&nbsp;dose&nbsp;(0.5 ml) contains 25 micrograms Vi polysaccharide of&nbsp;<em>Salmonella typhi<\/em>&nbsp;(Ty2 strain).<\/li><li>Other ingredients are phenol, sodium chloride, disodium hydrogen phosphate dihydrate, sodium dihydrogen phosphate dihydrate and water for&nbsp;injection&nbsp;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Typhim Vi is a clear, colorless solution.<\/p>\n\n\n\n<p><em>Package sizes:<\/em><\/p>\n\n\n\n<p>1 and 10 pre-filled syringes with attached or separate injection needle.<\/p>\n\n\n\n<p>1 and 10 pre-filled syringes without injection needle.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Sanofi Pasteur Europe<\/p>\n\n\n\n<p>14 Espace Henry Vall\u00e9e<\/p>\n\n\n\n<p>69007 Lyon<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong>&nbsp;:<\/p>\n\n\n\n<p>Sanofi Pasteur<\/p>\n\n\n\n<p>1541 Avenue Marcel M\u00e9rieux<\/p>\n\n\n\n<p>69280 Marcy L&#8217;\u00c9toile<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p>Sanofi Pasteur<\/p>\n\n\n\n<p>Incarville Industrial Park<\/p>\n\n\n\n<p>27100 Val de Reuil<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p><strong>Local representative:<\/strong><\/p>\n\n\n\n<p>Sanofi AB<\/p>\n\n\n\n<p>Box 30052<\/p>\n\n\n\n<p>104 25 Stockholm<\/p>\n\n\n\n<p>Phone: +46 8-634 50 00<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Typhim Vi is a vaccine used to protect against\u00a0typhoid fever\u00a0.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[26692,2212,26688,26693,26691,2356,26689,26690],"class_list":["post-25935","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-benefits-of-typhim-vi","tag-medicine","tag-typhim-vi","tag-typhim-vi-side-effects","tag-typhim-vi-vaccine","tag-vaccine","tag-what-is-typhim-vi","tag-what-typhim-vi-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25935","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=25935"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25935\/revisions"}],"predecessor-version":[{"id":25982,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25935\/revisions\/25982"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=25935"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=25935"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=25935"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}