0.75 mg, 1.5 mg, 3 mg, and 4.5 mg\u00a0solution for injection\u00a0in a pre-filled pen
dulaglutide<\/p>\n\n\n\n
Trulicity contains an active substance called dulaglutide. It is used to lower blood sugar ( glucose ) in adults with type 2 diabetes and may help prevent heart disease.<\/p>\n\n\n\n
In type 2\u00a0diabetes, your body does not produce enough\u00a0insulin, and the\u00a0insulin\u00a0your body produces does not work as well as it should.\u00a0When this happens, the sugar (\u00a0glucose\u00a0) accumulates in the blood.<\/p>\n\n\n\n
Trulicity is used:<\/p>\n\n\n\n
– alone if your blood sugar is not well controlled with diet and exercise alone and you cannot take metformin (another diabetes medicine).<\/p>\n\n\n\n
– or together with other medicines against\u00a0diabetes\u00a0when these are not enough to control your blood sugar level.\u00a0The other medicines can be those that are taken by mouth and\/or\u00a0the insulin\u00a0that you take by\u00a0injection.<\/p>\n\n\n\n
You must continue to follow the advice on diet and exercise that you receive from the doctor, pharmacist, or nurse.
<\/p>\n\n\n\n
– if you are allergic to dulaglutide or any other ingredient in this medicine (listed in section 6).<\/a><\/p>\n\n\n\n Talk to your doctor, pharmacist, or nurse before using Trulicity if:<\/p>\n\n\n\n – You are receiving dialysis because this medicine is not recommended.<\/p>\n\n\n\n – You have type 1\u00a0diabetes\u00a0(the type where the body does not produce any\u00a0insulin\u00a0) and this medicine may not be suitable for you.<\/p>\n\n\n\n – You have diabetic ketoacidosis (a complication of diabetes that occurs when the body cannot break down glucose because there is not enough insulin ). Signs of this are rapid weight loss, nausea or vomiting, a sweet-smelling breath, a sweet or metallic taste in your mouth, or a different smell to your urine or sweat.<\/p>\n\n\n\n – You have severe indigestion or problems with food staying in the stomach longer than normal (including gastroparesis).<\/p>\n\n\n\n – You have had pancreatitis (inflammation of the pancreas), which causes severe pain in the stomach and back that does not go away.<\/p>\n\n\n\n – You take a sulphonylurea or\u00a0insulin\u00a0for your\u00a0diabetes\u00a0because you can get low blood sugar (hypoglycemia).\u00a0Your doctor may need to change the\u00a0dose\u00a0of one of these other medicines to reduce the risk of this.<\/p>\n\n\n\n Trulicity is not insulin\u00a0and therefore should not be used as a substitute for\u00a0insulin.<\/p>\n\n\n\n When you start treatment with Trulicity, in some cases you may experience fluid loss\/dehydration, e.g.\u00a0in case of vomiting, nausea, and\/or diarrhea which can lead to reduced kidney function.\u00a0It is important to avoid dehydration by drinking plenty of fluids.\u00a0Contact your doctor if you have any questions or concerns.<\/p>\n\n\n\n When you start treatment with Trulicity, in some cases you may experience fluid loss\/dehydration, e.g.\u00a0in case of vomiting, nausea, and\/or diarrhea which can lead to reduced kidney function.\u00a0It is important to avoid dehydration by drinking plenty of fluids.\u00a0Contact your doctor if you have any questions or concerns.<\/p>\n\n\n\n Trulicity is not recommended for children and adolescents under 18 years of age as it has not been studied in these patients.<\/a><\/p>\n\n\n\n As Trulicity may decrease the rate of gastric emptying, which in turn may affect other medicines, tell your doctor, pharmacist or nurse if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n It is not known whether dulaglutide can harm your unborn baby.\u00a0Women of childbearing potential should use contraception during treatment with dulaglutide.\u00a0Tell your doctor if you are pregnant, think you may be pregnant, or are planning to become pregnant, as Trulicity should not be used during pregnancy.\u00a0Talk to your doctor about how best to control your blood sugar when you’re pregnant.<\/p>\n\n\n\n Talk to your doctor before taking this medicine if you want to breastfeed or are already breastfeeding.\u00a0Trulicity should not be used if you are breastfeeding.\u00a0It is not known whether dulaglutide passes into breast milk.<\/p>\n\n\n\n Trulicity has little or no effect on the ability to drive or use machines.\u00a0However, if you use Trulicity with a sulphonylurea or\u00a0insulin, you may experience low blood sugar (hypoglycemia), which may impair your ability to concentrate.\u00a0Avoid driving any vehicle or using machinery if you get signs of low blood sugar.\u00a0See section 2, \u201cWarnings and precautions\u201d, for information about the increased risk of low blood sugar, and section 4 for warning signs of low blood sugar.\u00a0Talk to your doctor if you need more information.<\/p>\n\n\n\n This medicine contains less than 1 mmol (23 mg) of\u00a0sodium\u00a0per\u00a0dose, i.e. it is almost ‘sodium-free’. Always use this medicine as directed by your doctor or pharmacist. Ask your doctor or pharmacist if you are not sure how to use this medicine.<\/p>\n\n\n\n Your doctor may recommend a dose of 0.75 mg once a week for your diabetes treatment. This is based on your individual needs, or if Trulicity is used alone.<\/p>\n\n\n\n When used alone, the doctor recommends a\u00a0dose\u00a0of\u00a00.75\u00a0mg once per week.\u00a0When used together with other diabetes medicines, the doctor may recommend a\u00a0dose\u00a0of\u00a01.5 mg once a week.<\/p>\n\n\n\n If your blood sugar is not controlled well enough, the doctor may increase the dose by one to 3 mg once a week.<\/p>\n\n\n\n If blood sugar control is still not sufficient, the dose can be further increased to 4.5 mg once weekly.<\/p>\n\n\n\n Each pen contains a weekly dose of Trulicity (0.75 mg, 1.5 mg, 3 mg, or 4.5 mg).\u00a0The pens are for single use only.<\/p>\n\n\n\n You can use the pen at any time of the day, with or without food. Take it on the same day of the week if you can. You can tick the day of the week you inject the first dose on the box or in a calendar to make it easier to remember.<\/p>\n\n\n\n Trulicity is injected under the skin ( subcutaneous injection ) in the abdomen or upper leg (thigh). If you receive an injection from someone else, it can be given in the upper arm.<\/p>\n\n\n\n If you want, you can inject in the same area of \u200b\u200bthe body every week. However, be sure to choose a new injection site within that area each time.<\/p>\n\n\n\n You must test your blood sugar as instructed by your doctor, pharmacist, or nurse if you are taking Trulicity together with a sulphonylurea or\u00a0insulin.<\/p>\n\n\n\n Read the user manual of the pen carefully before using Trulicity.<\/a><\/p>\n\n\n\n If you have used too much Trulicity, talk to your doctor immediately.\u00a0Too much of this medicine can cause your blood sugar to be too low (hypoglycemia) and make you feel sick or vomit.<\/p>\n\n\n\nWarnings and precautions<\/h2>\n\n\n\n
Children and young people<\/h2>\n\n\n\n
Other medicines and Trulicity<\/h2>\n\n\n\n
Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n
Driving ability and use of machinery<\/h2>\n\n\n\n
Trulicity contains sodium<\/h2>\n\n\n\n
<\/p>\n\n\n\nHow to use Trulicity<\/h2>\n\n\n\n
If you use too much Trulicity <\/h2>\n\n\n\n
If you forget to use Trulicity<\/h2>\n\n\n\n