{"id":25628,"date":"2022-09-23T11:02:27","date_gmt":"2022-09-23T11:02:27","guid":{"rendered":"https:\/\/zeepedia.com\/?p=25628"},"modified":"2022-09-24T08:03:10","modified_gmt":"2022-09-24T08:03:10","slug":"triaxis","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/triaxis\/","title":{"rendered":"Triaxis uses, dose and side effects"},"content":{"rendered":"\n<p>solution for injection,\u00a0suspension\u00a0in pre-filled\u00a0syringe<br>Vaccine against\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/diphtheria\/\">diphtheria<\/a>, tetanus, and pertussis (acellular, component),\u00a0adsorbed, with reduced antigen content<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Triaxis is and what it is used for<\/h2>\n\n\n\n<p>Triaxis (Tdap) is a vaccine.\u00a0Vaccines are used to protect against infectious diseases.\u00a0They work by causing the body to produce its protection against the bacteria that cause these diseases.<\/p>\n\n\n\n<p>This vaccine is used to boost protection against\u00a0diphtheria, tetanus, and pertussis in children from 4 years of age, adolescents, and adults, after a complete basic immunization.<\/p>\n\n\n\n<p>The use of Triaxis during pregnancy provides protection that can be transferred to the baby in the womb and protect the baby against <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cough-in-children\/\">whooping cough<\/a> during the first months of life.<\/p>\n\n\n\n<p><strong>Limitations of Coverage<\/strong><\/p>\n\n\n\n<p>Triaxis prevents these diseases only if they are caused by the bacteria that the vaccine targets.\u00a0You or your child can still get similar illnesses if they are caused by other bacteria or\u00a0viruses.<\/p>\n\n\n\n<p>Triaxis does not contain any live bacteria or&nbsp;viruses&nbsp;and it cannot cause any of the infectious diseases it protects against.<\/p>\n\n\n\n<p>Remember that no vaccine can provide complete, lifelong protection to all people vaccinated.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before Triaxis is given to you or your child<\/h2>\n\n\n\n<p>To be sure that Triaxis is suitable for you or your child, you must tell the doctor or nurse if any of the points below apply to you or your child.\u00a0If there is something you do not understand, ask the doctor or nurse to explain it.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Triaxis if you or your child<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>have had an allergic reaction:<ul><li>against vaccines against\u00a0diphtheria, tetanus, or whooping cough<\/li><li>against any of the other ingredients (specified in section 6)<\/li><li>against any residual substance from manufacturing (formaldehyde, glutaraldehyde), of which there may be trace amounts.<\/li><\/ul><\/li><li>ever had a serious reaction affecting the brain within a week of a previous\u00a0dose\u00a0of a pertussis vaccine<\/li><li>has an\u00a0acute\u00a0severe febrile illness.\u00a0Vaccination should be postponed until you or your child has recovered.\u00a0A mild illness without a <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">fever<\/a> is usually not a reason to postpone vaccination.\u00a0The doctor decides whether you or your child should receive Triaxis.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to a doctor or nurse before the vaccination if you or your child have<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>received a booster dose of a vaccine against\u00a0diphtheria\u00a0and tetanus within the last 4 weeks.\u00a0In this case, you or your child should not receive Triaxis and your doctor will decide based on official recommendations when you or your child can receive another\u00a0injection.<\/li><li>had\u00a0Guillain-Barr\u00e9 syndrome\u00a0(temporary loss of movement and feeling in all or part of the body) within 6 weeks of a previous\u00a0dose\u00a0of a tetanus vaccine.\u00a0The doctor decides whether you or your child should receive Triaxis.<\/li><li>an uncontrolled disease affecting the nervous system or uncontrolled epileptic seizures.\u00a0The doctor only starts treatment and vaccinates when the condition has stabilized.<\/li><li>weak or impaired immune system due to<ul><li>medication (eg\u00a0steroids,\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/treatment-of-cancer-in-children\/\">chemotherapy<\/a>,\u00a0or radiotherapy).<\/li><li>HIV\u00a0infection\u00a0or\u00a0AIDS.\u00a0_<\/li><li>any other disease.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>The vaccine may not protect as well as it protects people with healthy immune systems.&nbsp;If possible, vaccination should be postponed until such illness or treatment has ceased.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>any problem with the blood that makes bruising easy, or bleeding for a long time after a minor injury (for example, due to a blood disorder such as&nbsp;hemophilia&nbsp;or&nbsp;thrombocytopenia&nbsp;or treatment with blood-thinning medicines).<\/li><\/ul>\n\n\n\n<p>Fainting may occur after, or even before, any needle injection.\u00a0Therefore, tell the doctor or nurse if you or your child has fainted during a previous\u00a0injection.<\/p>\n\n\n\n<p>Tell your doctor, pharmacist, or nurse before using Triaxis if you or your child have had an\u00a0allergic reaction\u00a0to latex.\u00a0The tip covers of the pre-filled syringes contain a\u00a0derivative\u00a0of natural rubber (latex), which can cause an\u00a0allergic reaction.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Triaxis<\/h2>\n\n\n\n<p>Tell the doctor, nurse, or pharmacist if you or your child are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>As Triaxis does not contain live bacteria, it can generally be given at the same time as other vaccines or immunoglobulins but a different injection site.\u00a0Studies have shown that Triaxis can be used at the same time as any of the following vaccines: a hepatitis B vaccine, a <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/polio\/\">polio<\/a> vaccine (injected or taken by mouth), an inactivated influenza vaccine, and a\u00a0recombinant\u00a0human papillomavirus vaccine.\u00a0Injection\u00a0of several vaccines at the same time must be done in different parts of the body.<\/p>\n\n\n\n<p>If you or your child are receiving drug treatment that affects your or your child&#8217;s blood or immune system (such as blood-thinning drugs,\u00a0corticosteroids,\u00a0or\u00a0chemotherapy\u00a0), read the section &#8220;Warnings and precautions&#8221; above.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>Tell the doctor or nurse if you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby.\u00a0The doctor will help you decide if you should receive Triaxis during pregnancy.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>It has not been studied whether the vaccine affects the ability to drive or use machines.&nbsp;The vaccine has no or negligible effect on the ability to drive and use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with a doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How and when Triaxis is given<\/h2>\n\n\n\n<p><strong>When you or your child is given the vaccine<\/strong><\/p>\n\n\n\n<p>The doctor will decide whether Triaxis is suitable for you or your child depending on:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>which vaccines you or your child have received in the past<\/li><li>how many&nbsp;doses&nbsp;of similar vaccines you or your child have received before<\/li><li>when you or your child received the last&nbsp;dose&nbsp;of one of the similar vaccines<\/li><\/ul>\n\n\n\n<p>The doctor decides how long you should wait between vaccinations.<\/p>\n\n\n\n<p>If you are pregnant, your doctor will help you decide whether you should receive Triaxis during pregnancy.<\/p>\n\n\n\n<p><strong>Dosage&nbsp;and method of administration<\/strong><\/p>\n\n\n\n<p>Who gives you Triaxis?<\/p>\n\n\n\n<p>Triaxis should be given by healthcare professionals trained in giving vaccines and in a clinic or practice equipped to manage any rare serious&nbsp;allergic reaction&nbsp;to the vaccine.<\/p>\n\n\n\n<p>Dosage<\/p>\n\n\n\n<p>All age groups for which Triaxis is intended receive one&nbsp;injection&nbsp;(half a milliliter).<\/p>\n\n\n\n<p>If you or your child suffers an injury that requires preventive measures against tetanus, the doctor may decide to give Triaxis with or without\u00a0tetanus\u00a0immunoglobulin.<\/p>\n\n\n\n<p>Triaxis can be used for booster vaccination.&nbsp;The doctor will advise you about booster vaccination.<\/p>\n\n\n\n<p>Mode of administration<\/p>\n\n\n\n<p>The doctor or nurse will give you the vaccine into a muscle in your upper arm (the deltoid muscle).<\/p>\n\n\n\n<p>The doctor or nurse will\u00a0<strong>not<\/strong>\u00a0give you the vaccine in a blood vessel, in the buttocks, or under the skin.\u00a0In the case of a disturbance in the clotting ability of the blood, they may decide to inject under the skin, but this can cause more local\u00a0side effects, including a small lump under the skin.<\/p>\n\n\n\n<p>If you have any further questions about the use of this medicine, contact your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong><u>Severe allergic reactions<\/u><\/strong><\/p>\n\n\n\n<p><strong>If any of these symptoms occur after you leave the place where you or your child received an\u00a0injection, you must IMMEDIATELY contact a doctor:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>breathing difficulties<\/li><li>bluing of the tongue or lips<\/li><li>rash<\/li><li>swelling of the face or neck<\/li><li>low&nbsp;blood pressure&nbsp;that causes dizziness or collapse<\/li><\/ul>\n\n\n\n<p>If these signs or symptoms occur, they usually develop very quickly after the&nbsp;injection&nbsp;has been given and while you or your child are still in the clinic or doctor&#8217;s office.&nbsp;As with all vaccines, in very rare cases (in 1 in 10,000 patients) serious allergic reactions may occur.<\/p>\n\n\n\n<p><strong><u>Other\u00a0side effects\u00a0are<\/u><\/strong><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;were observed during&nbsp;clinical trials&nbsp;conducted in specific age groups.<\/p>\n\n\n\n<p>Children aged 4 to 6 years<\/p>\n\n\n\n<p>Very common (may affect more than 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>decreased appetite<\/li><li>headache<\/li><li>diarrhea<\/li><li>fatigue<\/li><li>pain<\/li><li>redness<\/li><li>swelling in the area where the vaccine was injected.<\/li><\/ul>\n\n\n\n<p>Common (may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>nausea<\/li><li>vomiting<\/li><li>rash<\/li><li>aches (in the whole body) or muscle weakness<\/li><li>aching or swollen joints<\/li><li>fever<\/li><li>overindulge<\/li><li>complaints from&nbsp;lymph nodes&nbsp;in the armpit.<\/li><\/ul>\n\n\n\n<p>Young people aged 11 to 17 years<\/p>\n\n\n\n<p>Very common (may affect more than 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache<\/li><li>diarrhea<\/li><li>nausea<\/li><li>aches (in the whole body) or muscle weakness<\/li><li>aching or swollen joints<\/li><li>fatigue\/weakness<\/li><li>general malaise<\/li><li>overindulge<\/li><li>pain<\/li><li>redness&nbsp;and swelling in the area where the vaccine was injected.<\/li><\/ul>\n\n\n\n<p>Common (may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>vomiting<\/li><li>rash<\/li><li>fever<\/li><li>complaints from&nbsp;lymph nodes&nbsp;in the armpit.<\/li><\/ul>\n\n\n\n<p>Adults aged 18 to 64 years<\/p>\n\n\n\n<p>Very common (may affect more than 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache<\/li><li>diarrhea<\/li><li>aches (in the whole body) or muscle weakness<\/li><li>fatigue\/weakness<\/li><li>general malaise<\/li><li>pain<\/li><li>redness&nbsp;and swelling in the area where the vaccine was injected.<\/li><\/ul>\n\n\n\n<p>Common (may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>nausea<\/li><li>vomiting<\/li><li>rash<\/li><li>aching or swollen joints<\/li><li>fever<\/li><li>overindulge<\/li><li>complaints from&nbsp;lymph nodes&nbsp;in the armpit.<\/li><\/ul>\n\n\n\n<p>The following additional\u00a0side effects\u00a0have been reported in the various recommended age groups during the commercial use of Triaxis.\u00a0The frequency of these\u00a0side effects\u00a0cannot be calculated precisely, as it would be based on voluntary reporting about an estimated number of vaccinated persons.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic\/severe allergic reactions (you can read about how to recognize such a reaction at the beginning of section 4), tingling or numbness, paralysis of part or the whole body (\u00a0Guillain-Barr\u00e9 syndrome\u00a0), nerve inflammation in the arm (brachial\u00a0neuritis\u00a0), loss of function of the nerve that controls the facial muscles (facial paralysis), seizures (convulsions), fainting,\u00a0inflammation\u00a0of the spinal cord (\u00a0myelitis\u00a0),\u00a0inflammation\u00a0of the heart muscle (\u00a0myocarditis\u00a0),\u00a0itching, hives,\u00a0inflammation\u00a0of a muscle (myositis), extensive swelling of the arm with\u00a0redness, warmth and tenderness or pain in the area where the vaccine was injected, bruising or boils in the area where the vaccine was injected.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Triaxis<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date stated on the label after \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in a refrigerator (2\u00b0C-8\u00b0C).\u00a0Do not freeze.\u00a0The frozen vaccines must be discarded.<\/p>\n\n\n\n<p>Store the syringe in the outer carton.&nbsp;Light sensitive.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>The active substances in each&nbsp;dose&nbsp;(0.5 ml) of vaccine are:<\/td><\/tr><tr><td>Diphtheria toxoid<\/td><td>not less than 2 international units (2 Lf)<\/td><\/tr><tr><td>Tetanus toxoid<\/td><td>not less than 20 international units (5 Lf)<\/td><\/tr><tr><td>Pertussis antigens<\/td><\/tr><tr><td>Pertussis toxoid<\/td><td>2.5 micrograms<\/td><\/tr><tr><td>Filamentous hemagglutinin<\/td><td>5 micrograms<\/td><\/tr><tr><td>Pertactin<\/td><td>3 micrograms<\/td><\/tr><tr><td>Fimbria types 2 and 3<\/td><td>5 micrograms<\/td><\/tr><tr><td>Adsorbed&nbsp;on aluminum phosphate<\/td><td>1.5 mg (0.33 mg Al&nbsp;<sup>3+<\/sup>&nbsp;)<\/td><\/tr><tr><td>This vaccine contains aluminum phosphate as an\u00a0adjuvant.\u00a0Adjuvants\u00a0are ingredients found in some vaccines to accelerate, enhance and\/or prolong the protective effect of the vaccine. Other ingredients are: phenoxyethanol, water for injections<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Triaxis is available as a&nbsp;suspension&nbsp;for&nbsp;injection&nbsp;in a pre-filled&nbsp;syringe&nbsp;(0.5 ml):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>without needle &#8211; packs of 1 or 10<\/li><li>with 1 or 2 separate needles \u2013 packs of 1 or 10<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<p>The normal appearance of the vaccine is a cloudy white&nbsp;suspension&nbsp;that may settle on storage.&nbsp;After thorough shaking, it is a&nbsp;homogeneous&nbsp;white liquid.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder:<\/h2>\n\n\n\n<p>Sanofi Pasteur Europe<\/p>\n\n\n\n<p>14 Espace Henry Vall\u00e9e<\/p>\n\n\n\n<p>69007 Lyon<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p><strong>Manufacturer:<\/strong><\/p>\n\n\n\n<p>Sanofi Pasteur<\/p>\n\n\n\n<p>14 Espace Henry Vall\u00e9e<\/p>\n\n\n\n<p>69007 Lyon<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p><strong>Local representative:<\/strong><\/p>\n\n\n\n<p>Sanofi AB<\/p>\n\n\n\n<p>Box 30052<\/p>\n\n\n\n<p>104 25 Stockholm<\/p>\n\n\n\n<p>Phone: +46 8-634 50 00<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Triaxis (Tdap) is a vaccine.\u00a0Vaccines are used to protect against infectious diseases.\u00a0They work by causing the body to produce its own protection against the bacteria that cause these diseases.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[26476,26473,26475,26474,2356,26477,26472,26471],"class_list":["post-25628","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-benefits-of-triaxis","tag-triaxis","tag-triaxis-side-effects","tag-triaxis-vaccine","tag-vaccine","tag-vaccine-against-diphtheria","tag-what-is-triaxis","tag-what-triaxis-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25628","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=25628"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25628\/revisions"}],"predecessor-version":[{"id":25674,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25628\/revisions\/25674"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=25628"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=25628"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=25628"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}