{"id":25592,"date":"2022-09-21T07:22:05","date_gmt":"2022-09-21T07:22:05","guid":{"rendered":"https:\/\/zeepedia.com\/?p=25592"},"modified":"2022-09-23T10:48:25","modified_gmt":"2022-09-23T10:48:25","slug":"tresuvi","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/tresuvi\/","title":{"rendered":"Tresuvi &#8211; Treprostinil uses, dose and side effects"},"content":{"rendered":"\n<p>1 mg\/ml, 2.5 mg\/ml, 5 mg\/ml and 10 mg\/ml&nbsp;infusion fluid&nbsp;, solution<br>treprostinil<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Tresuvi is and what it is used for<\/h2>\n\n\n\n<p><strong>What Tresuvi is<\/strong><\/p>\n\n\n\n<p>The active ingredient in Tresuvi is treprostinil.<\/p>\n\n\n\n<p>Treprostinil belongs to a group of drugs that work in almost the same way as naturally occurring\u00a0prostacyclins.\u00a0Prostacyclins\u00a0are hormone-like substances that lower\u00a0blood pressure\u00a0by causing the blood vessels to relax so that they widen, which makes blood flow easier.\u00a0Prostacyclin\u00a0er may also have an effect by preventing the blood from clotting.<\/p>\n\n\n\n<p><strong>What Tresuvi is used to treat<\/strong><\/p>\n\n\n\n<p>Tresuvi is used to treat\u00a0idiopathic\u00a0or hereditary\u00a0pulmonary\u00a0arterial\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/hypertension\/\">hypertension<\/a>\u00a0(PAH) in patients with moderately severe symptoms.\u00a0Pulmonary\u00a0arterial\u00a0hypertension\u00a0is a condition where the\u00a0blood pressure\u00a0is too high in the blood vessels between the heart and the lungs, causing shortness of breath, dizziness, fatigue, fainting, palpitations or abnormal heartbeats, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cough-in-children\/\">dry cough<\/a>, chest pain, and swollen ankles or legs.<\/p>\n\n\n\n<p>Tresuvi is initially given as a\u00a0continuous\u00a0subcutaneous\u00a0infusion\u00a0(\u00a0infusion\u00a0under the skin).\u00a0Some patients may not tolerate this due to pain and swelling at the administration site.\u00a0Your doctor will decide whether Tresuvi can instead be given as a\u00a0continuous\u00a0intravenous\u00a0infusion\u00a0(\u00a0infusion\u00a0into a vein).\u00a0This requires the insertion of a central\u00a0venous catheter, which is usually done in the neck, chest, or groin area.<\/p>\n\n\n\n<p><strong>How Tresuvi works<\/strong><\/p>\n\n\n\n<p>Tresuvi lowers&nbsp;blood pressure&nbsp;et in the pulmonary artery by improving blood flow and reducing the work of the heart.&nbsp;Improved blood flow leads to improved oxygen supply to the body and reduced strain on the heart, making it work more efficiently.&nbsp;Tresuvi improves the symptoms associated with PAH and the ability to exercise in patients who are limited in terms of activity.<\/p>\n\n\n\n<p>The treprostinil contained in Tresuvi may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Tresuvi<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Tresuvi<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to treprostinil or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have been diagnosed with a disease called &#8220;pulmonary veno-occlusive disease&#8221;.\u00a0This is a disease where the blood vessels that transport blood through the lungs become swollen and clogged, which causes increased pressure in the blood vessels between the heart and the lungs.<\/li><li>if you have severe liver disease<\/li><li>if you have heart problems, for example:<ul><li>myocardial infarction (heart attack) within the last six months<\/li><li>severe changes in heart rate<\/li><li>severe coronary artery disease or unstable angina<\/li><li>heart defect has been diagnosed, for example, a valve that causes the heart to work poorly<\/li><li>heart disease that is not treated or not closely monitored by doctors<\/li><\/ul><\/li><li>if you have a particularly high risk of bleeding \u2013 for example, active\u00a0peptic ulcers, injuries, or other bleeding conditions<\/li><li>if you have had a\u00a0stroke\u00a0within the last 3 months or any other interruption of the blood supply to the brain.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor before using Tresuvi if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have any liver disease<\/li><li>have any kidney disease<\/li><li>have been told that you are medically obese (\u00a0BMI\u00a0of more than 30 kg\/m\u00a0<sup>2<\/sup>\u00a0)<\/li><li>have\u00a0HIV\u00a0(human immunodeficiency virus)\u00a0infection<\/li><li>have high\u00a0blood pressure\u00a0in the hepatic veins (portal hypertension)<\/li><li>have a congenital heart defect that affects blood flow through the heart<\/li><li>follows a low-sodium diet.<\/li><\/ul>\n\n\n\n<p>During treatment with Tresuvi, tell your doctor:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if your\u00a0blood pressure\u00a0drops (\u00a0hypotension\u00a0)<\/li><li>if you experience rapidly increasing difficulty breathing or persistent <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cough-in-children\/\">cough<\/a> (this may be related to congestion in the lungs or\u00a0asthma\u00a0or another condition),\u00a0consult your doctor immediately<\/li><li>if you have heavy bleeding, treprostinil may increase the risk by preventing the blood from clotting<\/li><li>if you develop a <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">fever<\/a> while receiving treprostinil\u00a0intravenously\u00a0or if the site of the intravenous catheter becomes red, swollen, and\/or painful to the touch, these may be signs of\u00a0infection.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>There are limited data for children and adolescents.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Tresuvi<\/h2>\n\n\n\n<p>Tell your doctor if you are using, have recently used, or might be using other medicines.<\/p>\n\n\n\n<p>Tell your doctor if you are taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>medicines used to treat\u00a0<strong>high\u00a0blood pressure<\/strong>\u00a0(antihypertensives or other vasodilators)<\/li><li>medicines used to increase\u00a0<strong>urine output<\/strong>\u00a0(\u00a0diuretics\u00a0), including\u00a0furosemide<\/li><li>medicines that prevent the\u00a0<strong>blood from clottings<\/strong>\u00a0(blood thinners), such as\u00a0warfarin,\u00a0heparin,\u00a0or nitric oxide-based agents<\/li><li>non-steroidal anti-inflammatory drugs (\u00a0NSAIDs\u00a0) (eg\u00a0aspirin,\u00a0ibuprofen\u00a0)<\/li><li>medicines that can increase or decrease the effect of treprostinil (eg gemfibrozil, rifampicin, trimethoprim, deferasirox,\u00a0phenytoin, carbamazepine, phenobarbital, St. John&#8217;s\u00a0wort\u00a0) because your doctor may need to adjust the\u00a0dose\u00a0of Tresuvi.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Tresuvi is not recommended if you are pregnant, planning to become pregnant, or think you may be pregnant unless your doctor considers it necessary.\u00a0The safety of this medicine, when used during pregnancy, has not been established.<\/p>\n\n\n\n<p>The use of contraception is strongly recommended during treatment with Tresuvi.<\/p>\n\n\n\n<p>Use of Tresuvi is not recommended during breastfeeding unless your doctor considers it necessary.\u00a0You should stop breastfeeding if you have been prescribed Tresuvi, as it is not known whether this medicine is excreted in breast milk.<\/p>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, consult your doctor before using this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Tresuvi may cause low\u00a0blood pressure\u00a0with dizziness or fainting.\u00a0In such conditions, you should not drive or use machines and you should ask your doctor for advice.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Tresuvi contains sodium<\/h2>\n\n\n\n<p>Tell your doctor if you are on a low-salt diet.&nbsp;He\/she will take into account that a&nbsp;vial&nbsp;of Tresuvi contains the following amount of sodium:<\/p>\n\n\n\n<p>Tresuvi 1 mg\/ml&nbsp;solution for infusion&nbsp;:<\/p>\n\n\n\n<p>This medicine contains 36.8 mg of\u00a0sodium\u00a0(the main ingredient in common\/table salt) per 10 ml\u00a0vial.\u00a0This corresponds to 1.8% of the maximum recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n<p>Tresuvi 2.5 mg\/ml&nbsp;solution for infusion&nbsp;:<\/p>\n\n\n\n<p>This medicine contains 37.3 mg of\u00a0sodium\u00a0(the main ingredient in common\/table salt) per 10 ml\u00a0vial.\u00a0This corresponds to 1.9% of the maximum recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n<p>Tresuvi 5 mg\/ml&nbsp;solution for infusion&nbsp;:<\/p>\n\n\n\n<p>This medicine contains 39.1 mg of\u00a0sodium\u00a0(the main ingredient in common\/table salt) per 10 ml\u00a0vial.\u00a0This corresponds to 2.0% of the maximum recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n<p>Tresuvi 10 mg\/ml&nbsp;solution for infusion&nbsp;:<\/p>\n\n\n\n<p>This medicine contains 37.4 mg of\u00a0sodium\u00a0(the main ingredient in common\/table salt) per 10 ml\u00a0vial.\u00a0This corresponds to 1.9% of the maximum recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Tresuvi<\/h2>\n\n\n\n<p>Always use this medicine as directed by your doctor.&nbsp;Consult a doctor if you are unsure.<\/p>\n\n\n\n<p><strong><u>Mode of administration<\/u><\/strong><\/p>\n\n\n\n<p>Tresuvi is given as a&nbsp;continuous&nbsp;infusion&nbsp;either:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>subcutaneously\u00a0(under the skin) through a narrow tube (cannula) placed in the abdomen or thigh<\/li><li>intravenously\u00a0via a tube (\u00a0catheter\u00a0) which is usually placed in the neck, chest, or groin area.<\/li><\/ul>\n\n\n\n<p>In both cases, Tresuvi is pushed through the pipe using a portable pump.<\/p>\n\n\n\n<p>Before you leave the hospital or clinic, the doctor will tell you how to prepare Tresuvi and at what speed the pump should give you Tresuvi.&nbsp;You also get information on how to use the pump correctly and what to do if it stops working.&nbsp;You also get information about who to contact in an emergency.<\/p>\n\n\n\n<p>Flushing the infusion line while connected may cause an accidental overdose.<\/p>\n\n\n\n<p>Tresuvi is diluted only when given intravenously:<\/p>\n\n\n\n<p><strong>For\u00a0intravenous\u00a0infusion<\/strong>\u00a0only: If Tresuvi is given as a\u00a0continuous\u00a0intravenous\u00a0infusion, dilute the treprostinil solution only with sterile water for injections or with 9 mg\/ml (0.9%) sodium chloride solution for injections (provided by your doctor).<\/p>\n\n\n\n<p>Adult patients<\/p>\n\n\n\n<p>Tresuvi is available as 1 mg\/ml, 2.5 mg\/ml, 5 mg\/ml or 10 mg\/ml&nbsp;solution for infusion&nbsp;.&nbsp;Your doctor will determine the infusion rate and infusion dose that is appropriate for your condition.<\/p>\n\n\n\n<p>Obese patients<\/p>\n\n\n\n<p>If you are overweight (weighing 30% or more than your ideal body weight), your doctor will determine the first and subsequent&nbsp;doses&nbsp;based on your ideal body weight.&nbsp;See also section 2, \u201cWarnings and precautions\u201d.<\/p>\n\n\n\n<p>Elderly<\/p>\n\n\n\n<p>Your doctor will determine the infusion rate and infusion dose that is appropriate for your condition.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>There are limited data for children and adolescents.<\/p>\n\n\n\n<p>Dose adjustment<\/p>\n\n\n\n<p>The infusion rate can be lowered or increased individually\u00a0<strong>only under medical supervision<\/strong>.<\/p>\n\n\n\n<p>The goal of adjusting the infusion rate is to establish an effective maintenance rate that improves the symptoms of\u00a0pulmonary\u00a0arterial\u00a0hypertension\u00a0while minimizing\u00a0potential\u00a0side effects.<\/p>\n\n\n\n<p>If your symptoms increase you need complete rest or are confined to a bed or chair, or if any physical activity causes discomfort and your symptoms occur at rest, do not increase the\u00a0dose\u00a0without a doctor&#8217;s prescription.\u00a0This medicine may no longer be enough to treat your illness and other treatment may be needed.<\/p>\n\n\n\n<p><strong>How can\u00a0infection\u00a0in the bloodstream be prevented during treatment with Tresuvi given\u00a0intravenously?<\/strong><\/p>\n\n\n\n<p>As with any long-term&nbsp;intravenous&nbsp;treatment, there is a risk of&nbsp;infection&nbsp;in the bloodstream.&nbsp;Your doctor will instruct you on how to avoid this.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use too much Tresuvi&nbsp;<\/h2>\n\n\n\n<p>If you accidentally overdose on this medicine, you may experience nausea, vomiting, diarrhea, low\u00a0blood pressure\u00a0(dizziness, feeling of intoxication or fainting), flushing, and\/or headache.<\/p>\n\n\n\n<p>If any of these effects become severe, contact a doctor or hospital immediately.&nbsp;Your doctor may reduce the&nbsp;dose&nbsp;or stop the&nbsp;infusion&nbsp;until the symptoms have disappeared.&nbsp;Treatment with Tresuvi solution for infusion is restarted at a&nbsp;dose&nbsp;recommended by your doctor.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Tresuvi<\/h2>\n\n\n\n<p>Always use Tresuvi as directed by your doctor or hospital specialist.&nbsp;Do not stop using Tresuvi unless your doctor tells you to.<\/p>\n\n\n\n<p>On the contrary, discontinuation or sudden dose reductions of treprostinil may cause pulmonary\u00a0arterial\u00a0hypertension\u00a0to return, with the risk of rapid and serious deterioration of your condition.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Very common (may affect more than 1 in 10 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dilated blood vessels with skin redness<\/li><li>pain or&nbsp;redness&nbsp;at the infusion site<\/li><li>skin discoloration or bruising at the infusion site<\/li><li>headache<\/li><li>rash<\/li><li>nausea<\/li><li>diarrhea<\/li><li>pain in the jaws.<\/li><\/ul>\n\n\n\n<p>Common (may affect up to 1 in 10 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness<\/li><li>vomiting<\/li><li>feeling intoxicated or fainting due to low\u00a0blood pressure<\/li><li>itching\u00a0or redness of the skin<\/li><li>swelling of the feet, ankles, and legs or fluid retention<\/li><li>bleeding such as epistaxis, coughing up blood, blood in the urine, bleeding in the gums, blood in the stool<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">joint pain<\/a><\/li><li>muscle pain<\/li><li>pain in the legs and\/or arms.<\/li><\/ul>\n\n\n\n<p>Has been reported (occurring in an unknown number of users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>infusion site\u00a0infection<\/li><li>wart formation at the infusion site<\/li><li>reduced number of\u00a0blood cells\u00a0(\u00a0platelets\u00a0) that cause the blood to clot (\u00a0thrombocytopenia\u00a0)<\/li><li>bleeding at the infusion site<\/li><li>tissue infection under the skin (\u00a0cellulitis\u00a0)<\/li><li>bone pain<\/li><li>skin rash with discoloration or raised nodules<\/li><li>too much blood pumped from the heart leads to shortness of breath, fatigue, swelling of the legs and abdomen due to fluid retention, and persistent cough.<\/li><\/ul>\n\n\n\n<p>Has been reported (occurring in an unknown number of users)<\/p>\n\n\n\n<p>Side effects&nbsp;associated with&nbsp;intravenous&nbsp;administration<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>inflammation\u00a0of the vein (\u00a0thrombophlebitis\u00a0)<\/li><li>bacterial infection in the bloodstream (bacteremia)* (see section 3)<\/li><li>severe bacterial infection in the blood (\u00a0septicemia\u00a0).<\/li><\/ul>\n\n\n\n<p>*life-threatening or fatal cases of bacterial infection in the bloodstream have been reported<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Tresuvi<\/h2>\n\n\n\n<p><strong>Keep this medicine out of the sight and reach of children.<\/strong><\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton and vial after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not use this medicine if you notice any damage to the vial, discoloration, or other signs of deterioration.\u00a0A\u00a0vial\u00a0of Tresuvi must be used or discarded within 30 days of the first opening.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p><em>Durability under&nbsp;continuous&nbsp;subcutaneous&nbsp;infusion<\/em><\/p>\n\n\n\n<p>A reservoir (\u00a0syringe\u00a0) of undiluted treprostinil administered\u00a0subcutaneously\u00a0is chemically, physically, and microbiologically stable for up to 72 hours at 37\u00b0C.\u00a0Other storage times and conditions of use are at the user&#8217;s own risk.<\/p>\n\n\n\n<p><em>Durability under&nbsp;continuous&nbsp;intravenous&nbsp;infusion<\/em><\/p>\n\n\n\n<p>A reservoir (\u00a0syringe\u00a0) of diluted treprostinil solution administered\u00a0intravenously\u00a0is chemically, physically, and microbiologically stable for up to 48 hours at 37\u00b0C in polyvinyl chloride, polypropylene, and glass (at concentrations of at least 0.004 mg\/ml).\u00a0However, to minimize the risk of\u00a0infection\u00a0in the bloodstream, the maximum time of use of diluted treprostinil must not exceed 24 hours.\u00a0Other storage times and conditions of use are at the user&#8217;s own risk.<\/p>\n\n\n\n<p>Any diluted solution left over must be discarded.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>The active substance is treprostinil.<\/p>\n\n\n\n<p>Tresuvi 1 mg\/ml&nbsp;solution for infusion&nbsp;:<\/p>\n\n\n\n<p>Each ml contains 1 mg treprostinil, as treprostinil sodium.<\/p>\n\n\n\n<p>Tresuvi 2.5 mg\/ml&nbsp;solution for infusion&nbsp;:<\/p>\n\n\n\n<p>Each ml contains 2.5 mg treprostinil, as treprostinil sodium.<\/p>\n\n\n\n<p>Tresuvi 5 mg\/ml&nbsp;solution for infusion&nbsp;:<\/p>\n\n\n\n<p>Each ml contains 5 mg of treprostinil, as treprostinil sodium.<\/p>\n\n\n\n<p>Tresuvi 10 mg\/ml&nbsp;solution for infusion&nbsp;:<\/p>\n\n\n\n<p>Each ml contains 10 mg of treprostinil, as treprostinil sodium<\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<p>sodium citrate, sodium chloride, sodium hydroxide,\u00a0hydrochloric acid\u00a0(for\u00a0pH\u00a0adjustment ), meta cresol, and water for injections.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Tresuvi is a clear, colorless to a slightly yellow solution without visible particles, contained in a 10 ml clear glass\u00a0vial\u00a0sealed with a rubber stopper and color-coded cap:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tresuvi 1 mg\/ml&nbsp;solution for infusion&nbsp;has a yellow rubber cap.<\/li><li>Tresuvi 2.5 mg\/ml&nbsp;solution for infusion&nbsp;has a blue rubber cap.<\/li><li>Tresuvi 5 mg\/ml&nbsp;solution for infusion&nbsp;has a green rubber cap.<\/li><li>Tresuvi 10 mg\/ml&nbsp;solution for infusion&nbsp;has a red rubber cap.<\/li><\/ul>\n\n\n\n<p>Each carton contains one\u00a0vial.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Orpha-Devel Handels und Vertriebs GmbH<\/p>\n\n\n\n<p>Wintergasse 85\/1B<\/p>\n\n\n\n<p>3002 Purkersdorf<\/p>\n\n\n\n<p>Austria<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>AOP Orphan Pharmaceuticals GmbH<\/p>\n\n\n\n<p>Leopold-Ungar-Platz 2<\/p>\n\n\n\n<p>1190 Vienna<\/p>\n\n\n\n<p>Austria<\/p>\n\n\n\n<p><strong>This medicine is approved in the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Austria<\/td><td>Treprostinil Orpha-Devel, Infusionsl\u00f6sung<\/td><\/tr><tr><td>Belgium<\/td><td>Tresuvi, Solution for&nbsp;perfusion<\/td><\/tr><tr><td>Croatia<\/td><td>Tresuvi, Otopina za infuzuu<\/td><\/tr><tr><td>Estonia<\/td><td>Tresuvi, Infusion store<\/td><\/tr><tr><td>France<\/td><td>Treposuvi, Solution pour&nbsp;perfusion<\/td><\/tr><tr><td>Germany<\/td><td>Tresuvi, Infusion solution<\/td><\/tr><tr><td>Ireland<\/td><td>Treposuvi, a Solution for\u00a0infusion<\/td><\/tr><tr><td>Italy<\/td><td>Tresuvi, Soluzione per infusione<\/td><\/tr><tr><td>Latvia<\/td><td>Treposuvi, sh\u0127idums inf\u016bzij\u0101m<\/td><\/tr><tr><td>Lithuania<\/td><td>Treposuvi, sh\u0102dums inf\u016bzij\u0101m Treposuvi, sh\u0102dums inf\u016bzij\u0101m<\/td><\/tr><tr><td>Malta<\/td><td>Tresuvi, Solution for&nbsp;infusion<\/td><\/tr><tr><td>Netherlands<\/td><td>Treposuvi, Oplossing voor infusion<\/td><\/tr><tr><td>Sweden<\/td><td>Tresuvi,\u00a0Infusion liquid, solution<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Treprostinil belongs to a group of drugs that work in almost the same way as the naturally occurring\u00a0prostacyclins\u00a0.\u00a0Prostacyclins\u00a0are hormone-like substances that lower\u00a0blood pressure\u00a0by causing the blood vessels to relax so that they widen, which makes blood flow easier.\u00a0Prostacyclin\u00a0er may also have an effect by preventing the blood from clotting.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[22640,26395,22636,22639,26391,26393,22637,26392,22638,26394],"class_list":["post-25592","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-benefits-of-treprostinil","tag-benefits-of-tresuvi","tag-treprostinil","tag-treprostinil-side-effects","tag-tresuvi","tag-tresuvi-side-effects","tag-what-is-treprostinil","tag-what-is-tresuvi","tag-what-treprostinil-is-used-for","tag-what-tresuvi-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25592","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=25592"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25592\/revisions"}],"predecessor-version":[{"id":25618,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25592\/revisions\/25618"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=25592"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=25592"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=25592"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}