{"id":25432,"date":"2022-09-17T07:43:55","date_gmt":"2022-09-17T07:43:55","guid":{"rendered":"https:\/\/zeepedia.com\/?p=25432"},"modified":"2022-09-19T06:59:11","modified_gmt":"2022-09-19T06:59:11","slug":"tramadol-retard-actavis","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/tramadol-retard-actavis\/","title":{"rendered":"Tramadol Retard Actavis &#8211; Tramadol hydrochloride uses, dose and side effects"},"content":{"rendered":"\n<p>100 mg, 150 mg, and 200 mg\u00a0prolonged-release tablets\u00a0are<br>tramadol <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/cardizem-unotard\/\">hydrochloride<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Tramadol Retard Actavis is and what it is used for<\/h2>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis is an analgesic drug.&nbsp;Tramadol&nbsp;Retard&nbsp;Actavis relieves pain by&nbsp;inhibiting&nbsp;certain substances in the&nbsp;central nervous system&nbsp;(in the brain and spinal cord)<\/p>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis can be used by adults and adolescents over 12 years of age.&nbsp;It is used in the treatment of moderate to severe pain.<\/p>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis is not suitable for children under 12 years of age.<\/p>\n\n\n\n<p>The tramadol contained in Tramadol\u00a0Retard\u00a0Actavis may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Tramadol Retard Actavis<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Tramadol Retard Actavis<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to tramadol hydrochloride or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have recently drunk too much alcohol or taken too many sleeping pills, painkillers, opiates, or other medicines that act via the brain (\u00a0psychopharmaceuticals\u00a0).<\/li><li>if you use certain medicines against depression (so-called MAO inhibitors) or if you have used such medicine in the last 14 days.<\/li><li>if you suffer from\u00a0epilepsy\u00a0that is not well controlled by medication.<\/li><li>as a treatment for withdrawal symptoms in drug addiction.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Tramadol&nbsp;Retard&nbsp;Actavis<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have recently had a head injury or increased pressure in the head (e.g. after an accident).<\/li><li>if you suffer from kidney or liver disease (see section 3. How to take Tramadol\u00a0Retard\u00a0Actavis).<\/li><li>if you have breathing difficulties.<\/li><li>if you tend to have\u00a0epilepsy\u00a0or convulsions, as the risk of seizures may increase.\u00a0Seizures have been reported in patients taking tramadol at the recommended\u00a0dose.\u00a0The risk may increase when the tramadol dose exceeds the highest recommended daily dose (400 mg).<\/li><li>if you suffer from depression and take antidepressants because some of them can interact with tramadol (see &#8220;Other medicines and Tramadol\u00a0Retard\u00a0Actavis&#8221;).<\/li><li>if you are addicted to opiates.<\/li><li>if you are in a state of shock (cold sweating can be a sign of this).<\/li><li>if you use other drugs or substances that act via the brain, including alcohol.<\/li><\/ul>\n\n\n\n<p>After long-term treatment (&gt;3 months) <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/headache\/\">headaches<\/a> may occur or worsen.<\/p>\n\n\n\n<p>When tramadol has been used to treat tension-type or cluster headaches or&nbsp;migraine&nbsp;(for which tramadol is not approved), cases of headache due to drug overuse have been reported.<\/p>\n\n\n\n<p>Please note that Tramadol\u00a0Retard\u00a0Actavis can cause physical and psychological dependence.\u00a0When Tramadol\u00a0Retard\u00a0Actavis is taken for a longer period, the effect may decrease and higher\u00a0doses\u00a0may become necessary (\u00a0tolerance development\u00a0).\u00a0Patients with a tendency to drug abuse or drug dependence should only be treated with Tramadol\u00a0Retard\u00a0Actavis for short periods and under strict medical supervision.<\/p>\n\n\n\n<p>Tramadol is converted into the liver by an\u00a0enzyme.\u00a0Some people have a variation of this\u00a0enzyme\u00a0and it can affect different people in different ways.\u00a0Some people may not get enough pain relief, while others are at greater risk of serious\u00a0side effects.\u00a0If you experience any of the following\u00a0side effects, stop taking this medicine and see a doctor immediately: slow or shallow breathing, confusion, sleepiness, small\u00a0pupils, nausea or vomiting, constipation, and poor appetite.<br><br>Talk to your doctor or pharmacist if you experience any of the following symptoms while taking Tramadol\u00a0RetardActavis: Extreme fatigue, loss of appetite, severe abdominal pain, nausea, vomiting, or low\u00a0blood pressure.\u00a0This can be a sign of adrenal cortex failure (low levels of\u00a0cortisol\u00a0).\u00a0Contact a doctor if you experience these symptoms.\u00a0The doctor will decide if you need to take hormone replacement.<\/p>\n\n\n\n<p>There is a small risk that you may get a so-called serotonin syndrome, which can occur after taking tramadol in combination with certain antidepressants or tramadol alone.&nbsp;Seek immediate medical attention if you experience any of the symptoms of this serious syndrome (see section 4, \u201cPossible side effects\u201d).<\/p>\n\n\n\n<p><br>Sleep-related breathing disorders<br>Tramadol\u00a0Retard\u00a0Actavis can cause sleep-related breathing disorders such as\u00a0sleep apnea\u00a0(breathing pauses during sleep) and sleep-related\u00a0hypoxemia\u00a0(low oxygen content in the blood).\u00a0The symptoms can be breathing pauses during sleep, awakenings during the night due to shortness of breath, difficulty maintaining sleep, or severe drowsiness during the day.\u00a0Contact a doctor if you or someone else notices these symptoms.\u00a0The doctor may consider lowering your\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Tramadol is not recommended for children and adolescents with respiratory problems because the symptoms of tramadol poisoning may be worse in these children and adolescents.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Tramadol Retard Actavis<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Do not take Tramadol&nbsp;Retard&nbsp;Actavis at the same time as or within 14 days of taking medicines called monoamine oxidase inhibitors (<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/aurorix\/\">moclobemide<\/a> or phenelzine for depression,&nbsp;selegiline&nbsp;for&nbsp;Parkinson&#8217;s disease&nbsp;).<\/p>\n\n\n\n<p>Concomitant use of Tramadol\u00a0Retard\u00a0Actavis and sedative drugs or drugs for sleep disorders such as\u00a0benzodiazepines\u00a0or similar drugs increases the risk of drowsiness, breathing difficulties (\u00a0respiratory depression\u00a0),\u00a0coma,\u00a0and can be life-threatening.\u00a0Because of this, concomitant use should only be considered when other treatment options are not possible.<\/p>\n\n\n\n<p>If the doctor prescribes Tramadol&nbsp;Retard&nbsp;Actavis at the same time as sedative drugs, the&nbsp;dose&nbsp;and duration of treatment must be limited by the doctor.<\/p>\n\n\n\n<p>Tell the doctor if you are taking any sedative medication and follow the doctor&#8217;s instructions carefully<\/p>\n\n\n\n<p>and dosage recommendations.\u00a0It may be helpful to inform friends or relatives to be aware of the signs and symptoms described above.\u00a0Contact a doctor if you experience any of these symptoms.<\/p>\n\n\n\n<p>The pain-relieving effect of Tramadol&nbsp;Retard&nbsp;Actavis can be weakened and\/or shortened if you also take medicines that contain:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>carbamazepine (used in the treatment of&nbsp;epilepsy&nbsp;)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/bunalict\/\">buprenorphine<\/a>, nalbuphine or pentazocine (pain relievers)<\/li><li>ondansetron (used for nausea)<\/li><\/ul>\n\n\n\n<p>The risk of&nbsp;side effects&nbsp;increases:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are taking medicines that can cause convulsions (seizures), such as some antidepressants and antipsychotic medicines.\u00a0The risk of having a seizure may increase if you take Tramadol\u00a0Retard\u00a0Actavis at the same time.\u00a0Your doctor will tell you if Tramadol\u00a0Retard\u00a0Actavis is right for you.<\/li><li>if you are taking certain antidepressants.\u00a0Tramadol\u00a0Retard\u00a0Actavis may affect these medicines and you may develop serotonin syndrome (see section 4, &#8220;Possible side effects&#8221;).<\/li><li>if you take Tramadol\u00a0Retard\u00a0Actavis together with sedatives such as sedatives, sleeping pills, antidepressants, and strong pain relievers (morphine,\u00a0codeine, pethidine).\u00a0You may feel very drowsy or faint.<\/li><li>if you take Tramadol\u00a0Retard\u00a0Actavis together with blood-thinning medicines such as\u00a0warfarin.\u00a0The dose\u00a0of one of these medicines may need to be reduced, otherwise, there may be an increased risk of serious bleeding.<\/li><li>anticonvulsant drugs taken with tramadol may lower the seizure threshold and the risk of seizures may increase in these patients.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Tramadol Retard Actavis with alcohol<\/h2>\n\n\n\n<p>Do not drink alcohol during treatment with Tramadol Retard Actavis.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>Tramadol passes from the placenta to the fetus.\u00a0There is not enough information to know if it produces harmful effects on humans.\u00a0Long-term treatment during pregnancy can lead to the newborn child developing withdrawal symptoms.\u00a0Therefore, tramadol should not be used during pregnancy.\u00a0Consult with your doctor about what is most suitable for you.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Tramadol is excreted in breast milk.\u00a0You should therefore not take Tramadol\u00a0Retard\u00a0Actavis more than once during breastfeeding.\u00a0Alternatively, if you take Tramadol\u00a0Retard\u00a0Actavis more than once, you should stop breastfeeding.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Tramadol\u00a0Retard\u00a0Actavis can cause drowsiness, dizziness, and blurred vision.\u00a0This may affect your ability to drive and operate machinery.\u00a0These effects can be enhanced by alcohol or by medications that act on or work via the brain.\u00a0Do not drive or perform other activities that require alertness until you know how tramadol affects you.\u00a0See section 4. \u201cPossible side effects\u201d for a full list of possible\u00a0side effects\u00a0that may impair your attention and coordination.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Tramadol Retard Actavis<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Dose<\/p>\n\n\n\n<p>Does\u00a0one should be adjusted to the severity of your pain and your pain sensitivity.\u00a0Usually, you should take the lowest\u00a0dose\u00a0that provides pain relief.<\/p>\n\n\n\n<p>The usual\u00a0dose\u00a0is:<\/p>\n\n\n\n<p><em>Adults and adolescents over 12 years of age:<\/em><\/p>\n\n\n\n<p>The starting dose is:<\/p>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis 100 mg: one tablet (100 mg tramadol hydrochloride) twice daily.&nbsp;If it does not provide sufficient pain relief, the&nbsp;dose&nbsp;can be increased to:<\/p>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis 150 mg: one tablet (150 mg tramadol hydrochloride) twice daily or<\/p>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis 200 mg: one tablet (200 mg tramadol hydrochloride) twice daily.<\/p>\n\n\n\n<p>If the\u00a0dose\u00a0you are prescribed cannot be achieved with this tablet&#8217;s strength, the medicine is available in other strengths.<\/p>\n\n\n\n<p><em>Elderly patients<\/em><\/p>\n\n\n\n<p>For elderly patients (over 75 years), it may take longer for tramadol to disappear from the body.\u00a0If this concerns you, your doctor may advise you to extend the time between\u00a0doses.<\/p>\n\n\n\n<p><em>Severe liver or kidney failure\/dialysis patients<\/em><\/p>\n\n\n\n<p>Patients with severe liver and\/or\u00a0kidney failure\u00a0should not take Tramadol\u00a0Retard\u00a0Actavis.\u00a0If you have mild or moderate liver and\/or\u00a0kidney failure, your doctor may recommend you extend the time between\u00a0doses.<\/p>\n\n\n\n<p><em>How to take Tramadol&nbsp;Retard&nbsp;Actavis<\/em><\/p>\n\n\n\n<p>Tramadol\u00a0Retard\u00a0Actavis is a tablet with a special core designed to release the active substance slowly over a longer period.\u00a0Because of this, it may take a little longer before you notice the effect.<\/p>\n\n\n\n<p>Swallow the tablet whole (without chewing or crushing it) with a glass of water.\u00a0Preferably take the tablet in the morning and the evening.\u00a0The tablets can be taken on an empty stomach or during a meal.<\/p>\n\n\n\n<p><em>Duration of treatment with Tramadol&nbsp;Retard&nbsp;Actavis<\/em><\/p>\n\n\n\n<p>Your doctor will tell you how long to use Tramadol&nbsp;Retard&nbsp;Actavis.&nbsp;It depends on the cause of the pain.&nbsp;Do not use Tramadol&nbsp;Retard&nbsp;Actavis for longer than necessary.<\/p>\n\n\n\n<p>Talk to your doctor or pharmacist if you feel that the effect of Tramadol&nbsp;Retard&nbsp;Actavis is too strong or weak.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Tramadol Retard Actavis<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<p>Possible symptoms that may occur are small\u00a0pupils, vomiting, drop in blood pressure, palpitations, collapse, impaired consciousness including\u00a0coma\u00a0(deep unconsciousness), epileptic seizures, and breathing difficulties.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Tramadol Retard Actavis<\/h2>\n\n\n\n<p>If you forget to take tablets, the pain is likely to return.\u00a0Do not take a double\u00a0dose\u00a0to make up for missed\u00a0doses, just continue taking the medicine as before.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Tramadol Retard Actavis<\/h2>\n\n\n\n<p>If you stop or stop treatment with Tramadol&nbsp;Retard&nbsp;Actavis too soon, the pain is likely to return.<\/p>\n\n\n\n<p>You should not suddenly stop taking this medicine unless your doctor tells you to.&nbsp;If you want to stop taking your medicine, you should first discuss it with your doctor, especially if you have been taking it for a long time.&nbsp;The doctor will tell you when and how to stop, which can be done by gradually lowering the&nbsp;dose&nbsp;to reduce the risk of developing unnecessary&nbsp;side effects&nbsp;(withdrawal symptoms).<\/p>\n\n\n\n<p>In general, no side effects occur when the treatment with Tramadol\u00a0Retard\u00a0Actavis ends.\u00a0However, in rare cases, people who have abruptly stopped taking Tramadol\u00a0Retard\u00a0Actavis have experienced discomfort.\u00a0They may experience restlessness, anxiety, nervousness, and shakiness.\u00a0They may become hyperactive, have difficulty falling asleep, and experience gastrointestinal distress.\u00a0A few people may suffer from panic attacks, hallucinations, unusual sensations such as\u00a0itching, tingling and numbness, and ringing in the ears (\u00a0tinnitus\u00a0).\u00a0If you experience any of these discomforts after stopping Tramadol\u00a0Retard\u00a0Actavis consult your doctor.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor or pharmacist.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;may occur:<\/p>\n\n\n\n<p><em>Very common (may affect more than 1 in 10 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Nausea and dizziness.<\/li><\/ul>\n\n\n\n<p><em>Common (may affect up to 1 in 10 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache, vomiting, constipation,\u00a0dry mouth, sweating.<\/li><\/ul>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Palpitations, irregular heartbeats, low\u00a0blood pressure\u00a0(especially when standing up), cardiovascular collapse, retching, feeling of pressure in the stomach, feeling of fullness,\u00a0itching, rashes and special rashes with severe\u00a0itching\u00a0(hives or\u00a0hives\u00a0), diarrhea.<\/li><\/ul>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Blurred vision, slower heart rate than normal, increased\u00a0blood pressure, changes in appetite,\u00a0itching\u00a0or tingling sensation for no reason, tremors, slower than normal breathing, convulsions, hallucinations, confusion, sleep disturbances, and nightmares.\u00a0Allergic reactions (e.g. shortness of breath), tightness in the chest due to spasm in the muscles of the respiratory tract (\u00a0bronchospasm\u00a0), gasping, sudden accumulation of fluid in the skin and mucous membranes (e.g. in the throat and tongue), difficulty breathing and\/or\u00a0itching and hypersensitivity.\u00a0The following have also been reported: mood changes, changes in activity level, disturbances in perception or ability to make decisions, muscle weakness, difficulty throwing water, involuntary muscle contractions, impaired coordination, and fainting.<\/li><\/ul>\n\n\n\n<p><em>Has been reported (occurring in an unknown number of users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dilated\u00a0pupils, low blood sugar, hiccups, serotonin syndrome, which may manifest as altered mental status (e.g. anxiety, hallucinations,\u00a0coma\u00a0) and other symptoms such as fever, increased heart rate, unstable\u00a0blood pressure, involuntary twitching, muscle stiffness, lack of coordination of movements and\/or symptoms from the gastrointestinal tract (eg nausea, vomiting, diarrhea) (see section 2 &#8220;What you need to know before you take Tramadol\u00a0Retard\u00a0Actavis&#8221;).<\/li><\/ul>\n\n\n\n<p>Adverse effects&nbsp;that may occur upon discontinuation of treatment are identical to those upon&nbsp;withdrawal&nbsp;from opiates and may include: restlessness, anxiety, fear, nervousness, insomnia, motor restlessness (hyperkinesia), shaking (&nbsp;tremor&nbsp;), and gastrointestinal disturbances.<\/p>\n\n\n\n<p>Allergic reactions (eg difficulty breathing, wheezing, skin swelling) and\u00a0shock\u00a0(sudden\u00a0circulatory failure\u00a0) have occurred very rarely (in fewer than 1 in 10,000 users).\u00a0<strong>Contact a doctor immediately if you experience symptoms such as the <\/strong>swollen face, tongue, and\/or throat with\/or without difficulty swallowing or\u00a0hives\u00a0with difficulty breathing.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Tramadol Retard Actavis<\/h2>\n\n\n\n<p>Store out of sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date stated on the blister card and\/or the can after &#8220;Exp:&#8221; or &#8220;EXP:&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in the original packaging.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to deal with medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<p>&#8211; The active substance is tramadol hydrochloride.<\/p>\n\n\n\n<p>One tablet of Tramadol&nbsp;Retard&nbsp;Actavis 100 mg contains 100 mg of tramadol hydrochloride.<\/p>\n\n\n\n<p>One tablet of Tramadol Retard Actavis 150 mg contains 150 mg of tramadol hydrochloride.<\/p>\n\n\n\n<p>One tablet of Tramadol&nbsp;Retard&nbsp;Actavis 200 mg contains 200 mg of tramadol hydrochloride.<\/p>\n\n\n\n<p>&#8211; Other ingredients are <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/calcichew-d-3-spearmint\/\">calcium<\/a> hydrogen phosphate (E341), hydroxypropyl cellulose (E463),\u00a0colloidal\u00a0silicon dioxide (E551), and magnesium stearate (E470b).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis 100 mg tablets are off-white, round, biconvex tablets.<\/p>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis 150 mg tablets are off-white, capsule-shaped tablets.<\/p>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis 200 mg tablets are off-white, capsule-shaped tablets.<\/p>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis 100 mg: packs of 10, 20, 30, 50, 60, 90, 100, 120, 180 or 500 tablets in blister cards or in plastic cans.<\/p>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis 150 mg: packs of 10, 20, 30, 50, 60, 90, 100, 120, 180 or 500 tablets in blister cards or in plastic cans.<\/p>\n\n\n\n<p>Tramadol&nbsp;Retard&nbsp;Actavis 200 mg: packs of 10, 20, 30, 50, 60, 90, 100, 120, 180 or 500 tablets in blister cards or in plastic cans.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><em><br>Marketing authorization holder<\/em><br>Actavis Group PTC EHF.<\/p>\n\n\n\n<p>Reykjavik travel guide 76-78<\/p>\n\n\n\n<p>IS-220 Hafnarfjordur<\/p>\n\n\n\n<p>Iceland<\/p>\n\n\n\n<p><em>Manufacturer<\/em><\/p>\n\n\n\n<p>Farmaceutisch Analytisch Laboratorium Duvien BV<\/p>\n\n\n\n<p>Dijkgraaf 30<\/p>\n\n\n\n<p>NL-6921 RL Pigeon<\/p>\n\n\n\n<p>Holland<br><\/p>\n\n\n\n<p>Medochemie Ltd, Facility A \u2013 Z<\/p>\n\n\n\n<p>Ayios Athanasios Industrial St<br>Limassol<\/p>\n\n\n\n<p>Cyprus<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tramadol\u00a0Retard\u00a0Actavis is an analgesic drug.\u00a0Tramadol\u00a0Retard\u00a0Actavis relieves pain by\u00a0inhibiting\u00a0certain substances in the\u00a0central nervous system\u00a0(in the brain and spinal cord)<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[5337,5339,5340,26271,26275,26274,5338,26272,14539,26273],"class_list":["post-25432","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-tramadol-hydrochloride","tag-tramadol-hydrochloride-side-effects","tag-tramadol-hydrochloride-tablet","tag-tramadol-retard-actavis","tag-tramadol-retard-actavis-side-effects","tag-tramadol-retard-actavis-tablet","tag-what-is-tramadol-hydrochloride","tag-what-is-tramadol-retard-actavis","tag-what-tramadol-hydrochloride-is-used-for","tag-what-tramadol-retard-actavis-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25432","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=25432"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25432\/revisions"}],"predecessor-version":[{"id":25481,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25432\/revisions\/25481"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=25432"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=25432"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=25432"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}