{"id":25366,"date":"2022-09-15T07:32:24","date_gmt":"2022-09-15T07:32:24","guid":{"rendered":"https:\/\/zeepedia.com\/?p=25366"},"modified":"2022-09-17T07:34:22","modified_gmt":"2022-09-17T07:34:22","slug":"trajenta","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/trajenta\/","title":{"rendered":"Trajenta &#8211; Linagliptin uses, dose and side effects"},"content":{"rendered":"\n<p>5 mg&nbsp;film-coated tablets<br>Linagliptin<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Trajenta is and what it is used for<\/h2>\n\n\n\n<p>Trajenta contains the active ingredient linagliptin.&nbsp;It belongs to a group of medicines called &#8220;oral <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/diabetes-type-1\/\">diabetes<\/a> medicines&#8221;.&nbsp;Oral diabetes medications are used to treat high <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/diabetes-type-1\/\">blood sugar levels<\/a>.&nbsp;They work by helping your body reduce <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/diabetes-type-1\/\">blood sugar<\/a> levels.<\/p>\n\n\n\n<p>Trajenta is used for type 2\u00a0diabetes\u00a0in adults if the disease cannot be adequately controlled with a diabetes medicine (\u00a0metformin\u00a0or sulphonylureas) or diet and exercise alone.\u00a0Trajenta can be used together with other diabetes medicines<\/p>\n\n\n\n<p>\u00a0for example\u00a0metformin, sulfonylureas (eg, glimepiride, glipizide), empagliflozin, or\u00a0insulin.<\/p>\n\n\n\n<p>It is important to follow the advice on diet and exercise that you have been given by your doctor or nurse.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Trajenta<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Trajenta<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to linagliptin or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using Trajenta if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have type 1\u00a0diabetes\u00a0(your body does not produce any\u00a0insulin\u00a0) or diabetic\u00a0ketoacidosis\u00a0(a complication of\u00a0diabetes\u00a0with high blood sugar, rapid weight loss, nausea, and vomiting).\u00a0Trajenta should not be used in the treatment of these conditions.<\/li><li>if you use an antidiabetic medicine called a sulphonylurea (eg glimepiride, glipizide) your doctor may want to lower the\u00a0dose\u00a0of a sulphonylurea when you use it with Trajenta to avoid your blood sugar getting too low.<\/li><li>if you have had allergic reactions to other medicines that you used to control the amount of sugar in your blood.<\/li><li>have or have had a disease of the pancreas.<\/li><\/ul>\n\n\n\n<p>Contact your doctor if you have symptoms of\u00a0acute\u00a0pancreatitis, such as severe and persistent stomach pain (abdominal pain).<\/p>\n\n\n\n<p>If you get blisters on your skin, it could be a sign of a condition called bullous\u00a0pemphigoid.\u00a0Your doctor may tell you to stop taking Trajenta.<\/p>\n\n\n\n<p>Diabetic skin lesions are a common complication of\u00a0diabetes.\u00a0You should follow the skin and foot care recommendations you receive from your doctor or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Trajenta is not recommended for children and adolescents under the age of 18.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Trajenta<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are using, have recently used, or might be using other medicines.<\/p>\n\n\n\n<p>It is especially important to tell the doctor if you are using medicines that contain any of the following active ingredients:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>carbamazepine, phenobarbital or\u00a0phenytoin\u00a0.\u00a0These are medicines used for cramps or\u00a0chronic\u00a0pain.<\/li><li>rifampicin.\u00a0It is an\u00a0antibiotic\u00a0used to treat\u00a0infections\u00a0such as\u00a0tuberculosis.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<p>It is not known whether Trajenta is harmful to an unborn baby.&nbsp;Therefore, the use of Trajenta should be avoided if you are pregnant.<\/p>\n\n\n\n<p>It is not known whether Trajenta passes into breast milk.\u00a0Your doctor must decide if breastfeeding should be discontinued or if you should discontinue\/abstain from Trajenta treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Trajenta has no or negligible influence on the ability to drive or use machines.<\/p>\n\n\n\n<p>Using Trajenta together with medicines called sulphonylureas and\/or\u00a0insulin\u00a0can cause low blood sugar (hypoglycemia) which can affect your ability to drive and use machines and work without a secure footing.\u00a0However, more frequent testing of blood glucose levels may be recommended to minimize the risk of\u00a0hypoglycemia, especially when Trajenta is combined with sulfonylurea and\/or\u00a0insulin.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Trajenta<\/h2>\n\n\n\n<p>Always use this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one Trajenta tablet 5 mg once a day.<\/p>\n\n\n\n<p>You can take Trajenta with or without food.<\/p>\n\n\n\n<p>Your doctor may prescribe Trajenta together with another oral diabetes medicine.&nbsp;Remember to use all medications as directed by your doctor to achieve the best results for your health.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Trajenta<\/h2>\n\n\n\n<p>Talk to your doctor immediately if you have taken more Trajenta than you should.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Trajenta<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take a\u00a0dose\u00a0of Trajenta, take it as soon as you remember.\u00a0If it is almost time for the next\u00a0dose, skip the missed\u00a0dose.<\/li><li>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.\u00a0Never take two\u00a0doses\u00a0on the same day.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Trajenta<\/h2>\n\n\n\n<p>Do not stop using Trajenta without first consulting your doctor.&nbsp;Your blood sugar levels may increase when you stop using Trajenta.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><em>Some symptoms require immediate medical attention<\/em><\/p>\n\n\n\n<p>You should stop using Trajenta and see a doctor immediately if you experience any of the following symptoms of low blood sugar: tremors, sweating, restlessness, blurred vision, tingling lips, paleness, mood swings, or confusion (hypoglycemia).\u00a0Hypoglycemia\u00a0(frequency: very common, may affect more than 1 in 10 users) is an identified\u00a0side effect\u00a0when Trajenta is taken together with\u00a0metformin\u00a0and sulphonylurea.<\/p>\n\n\n\n<p>Some patients have experienced allergic reactions (hypersensitivity, frequency: uncommon, may affect up to 1 in 100 users) when using Trajenta alone or with other\u00a0diabetes\u00a0medicines, which may be serious, including wheezing and shortness of breath (bronchial hyperreactivity, frequency not known, the frequency cannot be estimated from available data).\u00a0Some patients have experienced skin rashes (frequency: uncommon), hives (\u00a0urticaria, frequency: rare, may affect up to 1 in 1,000 users), and swelling of the face, lips, tongue, and throat which may cause difficulty in breathing or swallowing (\u00a0angioedema, frequency: rare).\u00a0If you experience any of the symptoms listed above, stop taking Trajenta and contact your doctor immediately.\u00a0Your doctor may\u00a0prescribe\u00a0one medicine to treat your allergic reaction and another medicine for your\u00a0diabetes.<\/p>\n\n\n\n<p>Some patients have experienced\u00a0inflammation\u00a0of the pancreas (\u00a0pancreatitis, rare, may affect up to 1 in 1,000 users) when using Trajenta alone or with other medicines to treat\u00a0diabetes.<\/p>\n\n\n\n<p>STOP taking Trajenta and contact your doctor immediately if you notice any of the following serious side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe and persistent pain in the abdomen (stomach) that may radiate to the back, as well as nausea and vomiting, as this may be a sign of&nbsp;inflammation&nbsp;of the pancreas (&nbsp;pancreatitis&nbsp;).<\/li><\/ul>\n\n\n\n<p>Some patients have experienced the following&nbsp;side effects&nbsp;when using Trajenta alone or with other medicines to treat diabetes:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Common: increased level of&nbsp;lipase&nbsp;in the blood.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Uncommon:&nbsp;inflammation&nbsp;of the nose or throat (&nbsp;nasopharyngitis&nbsp;), <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cough-in-children\/\">cough<\/a>, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/constipation\/\">constipation<\/a> (in combination with&nbsp;insulin&nbsp;), increased level of amylase in the blood.<\/li><li>Rare: blistering of the skin (bullous&nbsp;pemphigoid&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Trajenta<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton and blister cards after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>This medicine does not require any special storage conditions.<\/p>\n\n\n\n<p>Do not use Trajenta if the package is damaged or the seal is broken.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to deal with medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is linagliptinEach film-coated tablet (tablet) contains 5 mg of linagliptin<\/li><li>Other ingredients are tablet core:\u00a0Mannitol, pregelatinized\u00a0starch\u00a0(corn), corn starch, copovidone, magnesium stearate film<em> coating:<\/em>\u00a0Hypromellose, titanium dioxide (E171), talc, macrogol (6000), red iron oxide (E172)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Trajenta 5 mg tablets are 8 mm diameter round, light red, film-coated tablets debossed with \u201cD5\u201d on one side and the Boehringer Ingelheim logo on the other side.<\/li><li>Trajenta is available in perforated aluminum\/aluminum single-dose blisters.&nbsp;The pack sizes are 10 x 1, 14 x 1, 28 x 1, 30 x 1, 56 x 1, 60 x 1, 84 x 1, 90 x 1, 98 x 1, 100 x 1 and 120 x 1 tablets.<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder:<\/strong><\/p>\n\n\n\n<p>Boehringer Ingelheim International GmbH<\/p>\n\n\n\n<p>Binger Strasse 173<\/p>\n\n\n\n<p>D-55216 Ingelheim am Rhein<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Boehringer Ingelheim Pharma GmbH &amp; Co.&nbsp;KG<\/p>\n\n\n\n<p>Binger Strasse 173<\/p>\n\n\n\n<p>D-55216 Ingelheim am Rhein<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>alternatively<\/p>\n\n\n\n<p>Boehringer Ingelheim Hellas Single Member SA<\/p>\n\n\n\n<p>5th km Paiania \u2013 Markopoulo<\/p>\n\n\n\n<p>Koropi Attiki, 19441<\/p>\n\n\n\n<p>Greece<\/p>\n\n\n\n<p>alternatively<\/p>\n\n\n\n<p>Dragenopharm Apotheker P\u00fcschl GmbH<\/p>\n\n\n\n<p>G\u00f6llstrasse 1<\/p>\n\n\n\n<p>84529 Tittmoning<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgi\u00eb\/Belgique\/Belgien<\/strong>SCS Boehringer Ingelheim Comm.VT\u00e9l\/Tel: +32 2 773 33 11<\/td><td><strong>Lithuania<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KG Lietuvos filialasTel.: +370 5 2595942<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>B\u00f6ringer Ingelheim \u0420\u0426\u0412 \u0413\u043c\u0431\u0425 \u0438 \u041a\u043e \u041a\u0413 &#8211; branch \u0411\u044a\u043b\u0433\u0430\u0440\u0441\u043a\u0438Phone: +359 2 958 79 98<\/td><td><strong>Luxembourg\/Luxembourg<\/strong>SCS Boehringer Ingelheim Comm.VT\u00e9l\/Tel: +32 2 773 33 11<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Boehringer Ingelheim coil.\u00a0s iPhone: +420 234 655 111<\/td><td><strong>Magyarorsz\u00e1g<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KG Magyarorsz\u00e1gi Fi\u00f3ktelepeTel.: +36 1 299 8900<\/td><\/tr><tr><td><strong>Denmark<\/strong>Boehringer Ingelheim Danmark A\/SPhone: +45 39 15 88 88<\/td><td><strong>Malta<\/strong>Boehringer Ingelheim Ireland Ltd.Phone: +353 1 295 9620<\/td><\/tr><tr><td><strong>Deutschland<\/strong>Boehringer Ingelheim Pharma GmbH &amp; Co.&nbsp;KGPhone: +49 (0) 800 77 90 900<\/td><td><strong>The Netherlands<\/strong>Boehringer Ingelheim bvPhone: +31 (0) 800 22 55 889<\/td><\/tr><tr><td><strong>Estonia<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KG, Eesti branchPhone: +372 60 80 940<\/td><td><strong>Norway<\/strong>Boehringer Ingelheim Norway KSPhone: +47 66 76 13 00<\/td><\/tr><tr><td><strong>Greece<\/strong>Boehringer Ingelheim Ellas AETel: +30 2 10 89 06 300<\/td><td><strong>Austria<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KGPhone: +43 1 80 105-7870<\/td><\/tr><tr><td><strong>Spain<\/strong>Boehringer Ingelheim Espa\u00f1a, SAPhone: +34 93 404 51 00<\/td><td><strong>Polish<\/strong>Boehringer Ingelheim Sp.zo.o.Tel.: +48 22 699 0 699<\/td><\/tr><tr><td><strong>France<\/strong>Boehringer Ingelheim France SASTel: +33 3 26 50 45 33<\/td><td><strong>Portugal<\/strong>Boehringer Ingelheim Portugal, Lda.Phone: +351 21 313 53 00<\/td><\/tr><tr><td><strong>Hrvatska<\/strong>Boehringer Ingelheim Zagreb dooPhone: +385 1 2444 600<\/td><td><strong>Romania<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KG Viena &#8211; Sucursala BucurestiPhone: +40 21 302 2800<\/td><\/tr><tr><td><strong>Ireland<\/strong>Boehringer Ingelheim Ireland Ltd.Phone: +353 1 295 9620<\/td><td><strong>Slovenija<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KG, Podru\u017enica LjubljanaPhone: +386 1 586 40 00<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hf.Phone: +354 535 7000<\/td><td><strong>Slovenian Republic<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KG, organiza\u010dn\u00e1 zlo\u017ekaPhone: +421 2 5810 1211<\/td><\/tr><tr><td><strong>Italy<\/strong>Boehringer Ingelheim Italia SpAPhone: +39 02 5355 1<\/td><td><strong>Finland\/Finland<\/strong>Boehringer Ingelheim Finland KyPhone\/Tel: +358 10 3102 800<\/td><\/tr><tr><td><strong>Cyprus<\/strong>Boehringer Ingelheim Ellas AETel: +30 2 10 89 06 300<\/td><td><strong>Sweden<\/strong>Boehringer Ingelheim ABPhone: +46 8 721 21 00<\/td><\/tr><tr><td><strong>Latvia<\/strong>Boehringer Ingelheim RCV GmbH &amp; Co KGLatvijas filialePhone: +371 67 240 011<\/td><td><strong>United Kingdom (Northern Ireland)<\/strong>Boehringer Ingelheim Ireland Ltd.Phone: +353 1 295 9620<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Trajenta contains the active ingredient linagliptin.\u00a0It belongs to a group of medicines called &#8220;oral diabetes medicines&#8221;.\u00a0Oral diabetes medications are used to treat high blood sugar levels.\u00a0They work by helping your body reduce blood sugar levels.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[14125,14902,14128,26193,26195,26197,14126,26194,14127,26196],"class_list":["post-25366","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-linagliptin","tag-linagliptin-side-effects-2","tag-linagliptin-tablet","tag-trajenta","tag-trajenta-side-effects","tag-trajenta-tablet","tag-what-is-linagliptin","tag-what-is-trajenta","tag-what-linagliptin-is-used-for","tag-what-trajenta-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25366","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=25366"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25366\/revisions"}],"predecessor-version":[{"id":25425,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25366\/revisions\/25425"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=25366"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=25366"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=25366"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}