{"id":25365,"date":"2022-09-15T07:31:16","date_gmt":"2022-09-15T07:31:16","guid":{"rendered":"https:\/\/zeepedia.com\/?p=25365"},"modified":"2022-09-17T07:34:31","modified_gmt":"2022-09-17T07:34:31","slug":"tradolan-retard","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/tradolan-retard\/","title":{"rendered":"Tradolan Retard – Tramadol hydrochloride uses, dose and side effects"},"content":{"rendered":"\n

100 mg, 150 mg, 200 mg prolonged-release tablet
tramadol hydrochloride<\/a><\/a><\/p>\n\n\n\n

What Tradolan Retard is and what it is used for<\/h2>\n\n\n\n

Tramadol hydrochloride, the active substance in Tradolan\u00a0Retard, is an analgesic that belongs to the\u00a0opioid\u00a0class that acts on the\u00a0central nervous system.\u00a0Tramadol hydrochloride acts as a pain reliever by affecting specific nerve cells in the spinal cord and brain.<\/p>\n\n\n\n

Tradolan Retard is used for the treatment of moderate to severe pain.<\/p>\n\n\n\n

Tramadol hydrochloride contained in Tradolan\u00a0Retard\u00a0may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.
<\/p>\n\n\n\n

What you need to know before taking Tradolan Retard<\/h2>\n\n\n\n

Do not take Tradolan Retard<\/h2>\n\n\n\n

– if you are allergic to tramadol hydrochloride or any other ingredient in this medicine (listed in section 6);<\/p>\n\n\n\n

– if you have recently used alcohol, sleeping pills, painkillers, or\u00a0psychotropic drugs\u00a0(drugs that affect mood\/mood and emotional life);<\/p>\n\n\n\n

– if you simultaneously use MAO inhibitors (certain medicines for the treatment of depression) or have taken such medicines in the last 14 days before treatment with Tradolan Retard (see “Other medicines and Tradolan Retard”).<\/p>\n\n\n\n

– if you suffer from epilepsy that is not well controlled with treatment;<\/p>\n\n\n\n

– as a substitute for drug withdrawal.<\/a><\/p>\n\n\n\n

Warnings and precautions<\/h2>\n\n\n\n

Talk to a doctor or pharmacist before taking Tradolan\u00a0Retard.<\/p>\n\n\n\n

Take special care with Tradolan Retard:<\/p>\n\n\n\n

– if you suspect that you are or have been addicted to other painkillers (opioids\u00a0er);<\/p>\n\n\n\n

– if you suffer from a reduced level of consciousness (if you feel faint);<\/p>\n\n\n\n

– if you are in a state of shock (cold sweating can be a sign of this);<\/p>\n\n\n\n

– if you have increased pressure in the head (after a skull or brain injury);<\/p>\n\n\n\n

– if you have breathing difficulties;<\/p>\n\n\n\n

– if you are prone to epileptic seizures or convulsions, as the risk of seizures may increase;<\/p>\n\n\n\n

– if you have impaired liver or kidney function;<\/p>\n\n\n\n

– if you suffer from depression and take antidepressants because some of them can interact with tramadol (see “Other medicines and Tradolan Retard”).<\/p>\n\n\n\n

Sleep-related breathing disorders<\/p>\n\n\n\n

Tradolan\u00a0Retard\u00a0can cause sleep-related breathing disorders such as\u00a0sleep apnea\u00a0(breathing pauses during sleep) and sleep-related\u00a0hypoxemia\u00a0(low oxygen content in the blood).\u00a0The symptoms can be breathing pauses during sleep, awakenings during the night due to shortness of breath, difficulty maintaining sleep, or severe drowsiness during the day.\u00a0Contact a doctor if you or someone else notices these symptoms.\u00a0The doctor may consider lowering your\u00a0dose.<\/p>\n\n\n\n

Epileptic seizures have been reported in patients taking the recommended dose of tramadol. The risk may increase if the dose of tramadol exceeds the recommended upper daily dose (400 mg).<\/p>\n\n\n\n

Please note that Tradolan\u00a0Retard\u00a0can cause physical and psychological dependence.\u00a0When Tradolan\u00a0Retard\u00a0is taken for a longer period, the effect may decrease and higher\u00a0doses\u00a0may become necessary (\u00a0tolerance development\u00a0).\u00a0Patients with a tendency to drug abuse or who are dependent on drugs will be treated with Tradolan\u00a0Retard\u00a0only for short periods and under strict medical supervision.<\/p>\n\n\n\n

Extreme fatigue, loss of appetite, severe abdominal pain, nausea, vomiting, or low\u00a0blood pressure.\u00a0This can be a sign of adrenal cortex failure (low levels of\u00a0cortisol\u00a0).\u00a0Contact a doctor if you experience these symptoms.\u00a0The doctor will decide if you need to take hormone replacement.<\/p>\n\n\n\n

Tramadol is converted into the liver by an\u00a0enzyme.\u00a0Some people have a variation of this\u00a0enzyme\u00a0and it can affect different people in different ways.\u00a0Some people may not get enough pain relief, while others are at greater risk of serious\u00a0side effects.\u00a0If you experience any of the following\u00a0side effects, stop taking this medicine and see a doctor immediately: slow or shallow breathing, confusion, sleepiness, small\u00a0pupils, nausea or vomiting, constipation, and poor appetite.<\/p>\n\n\n\n

There is a small risk that you may get a so-called serotonin syndrome, which can occur after taking tramadol in combination with certain antidepressants or tramadol alone. Seek immediate medical attention if you experience any of the symptoms of this serious syndrome (see section 4, \u201cPossible side effects\u201d).<\/p>\n\n\n\n

If you stop taking Tramadol\u00a0Retard, especially after long-term treatment, your doctor will recommend tapering the\u00a0dose\u00a0to reduce withdrawal symptoms.<\/p>\n\n\n\n

Inform your doctor if one or more of these problems occur during treatment with Tradolan Retard or if they have affected you in the past.<\/a><\/p>\n\n\n\n

Children and young people<\/h2>\n\n\n\n

Tradolan Retard is not suitable for children under 12 years of age.<\/p>\n\n\n\n

Use in children and adolescents with breathing problems<\/p>\n\n\n\n

Tramadol is not recommended for children and adolescents with respiratory problems because the symptoms of tramadol poisoning may be worse in these children and adolescents.<\/a><\/p>\n\n\n\n

Other medicines and Tradolan Retard<\/h2>\n\n\n\n

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n

Tradolan Retard should not be taken together with MAO inhibitors (certain medicines for the treatment of depression).<\/p>\n\n\n\n

The pain-relieving effect of Tradolan Retard can be reduced and the duration of action can be shortened, if you simultaneously take other medicines that contain:<\/p>\n\n\n\n

– carbamazepine (for epilepsy );<\/p>\n\n\n\n

– ondansetron (for nausea).<\/p>\n\n\n\n

Concomitant use of Tradolan\u00a0Retard\u00a0and sedative drugs or drugs for sleep problems such as\u00a0benzodiazepines\u00a0or similar drugs increases the risk of sleepiness, breathing difficulties (\u00a0respiratory depression\u00a0),\u00a0and coma,\u00a0and can be life-threatening.\u00a0Because of this, concomitant use should only be considered when other treatment options are not possible.
If your doctor prescribes Tradolan\u00a0Retard\u00a0together with sedative drugs, the\u00a0dose\u00a0and duration of treatment must be limited by the doctor.
Tell your doctor about any sedative medications you take and follow your doctor’s dosage recommendations carefully.\u00a0It may be helpful to inform friends or relatives to be aware of the signs and symptoms listed above.\u00a0Contact a doctor if you experience such symptoms.<\/p>\n\n\n\n

The doctor assesses whether you can use Tradolan\u00a0Retard\u00a0and with what\u00a0dose.<\/p>\n\n\n\n

The risk of side effects increases if you<\/p>\n\n\n\n

– at the same time using sedatives, sleeping pills, other painkillers such as morphine and\u00a0codeine\u00a0(also as cough medicine), and alcohol with Tradolan\u00a0Retard.\u00a0You may feel drowsy and faint.\u00a0Tell the doctor if this happens.<\/p>\n\n\n\n

– taking medicines that can cause convulsions (seizures), such as certain antidepressants and antipsychotic medicines.\u00a0The risk of having a seizure may increase if you take Tradolan\u00a0Retard\u00a0at the same time.\u00a0Your doctor will tell you whether Tradolan\u00a0Retard\u00a0is a suitable medicine for you.<\/p>\n\n\n\n

– are taking certain antidepressants, as Tradolan Retard can interact with these medicines and you may develop serotonin syndrome (see section 4, “Possible side effects”).<\/p>\n\n\n\n

– taking\u00a0anticoagulants\u00a0of the coumarin type (blood-thinning drugs), eg\u00a0warfarin, together with Tradolan Retard.\u00a0The effect of these medicines on the blood’s ability to clot can be affected and bleeding can occur.<\/p>\n\n\n\n

Tradolan Retard with food and alcohol<\/h2>\n\n\n\n

Food does not affect the effect of Tradolan\u00a0Retard.\u00a0Do not drink alcohol when using Tradolan\u00a0Retard, as the\u00a0side effects\u00a0of this medicine may be increased.<\/p>\n\n\n\n

Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n

Pregnancy<\/p>\n\n\n\n

There is very little information on the safety of tramadol use during pregnancy.\u00a0Therefore, Tradolan\u00a0Retard\u00a0should not be used during pregnancy.\u00a0Long-term treatment during pregnancy may lead to habituation in the newborn (which may lead to changes in the respiratory rate in newborns).\u00a0Therefore, if you are pregnant, your doctor will only prescribe Tradolan\u00a0Retard\u00a0if necessary.<\/p>\n\n\n\n

Breast-feeding<\/p>\n\n\n\n

Tramadol is excreted in breast milk.\u00a0You should therefore not take Tradolan\u00a0Retard\u00a0more than once during breastfeeding.\u00a0Alternatively, if you take Tradolan\u00a0Retard\u00a0more than once, you should stop breastfeeding.<\/p>\n\n\n\n

Fertility<\/p>\n\n\n\n

Experience based on humans does not indicate that tramadol affects female or male\u00a0fertility.<\/p>\n\n\n\n

Driving ability and use of machinery<\/h2>\n\n\n\n

Tramadol can cause drowsiness, dizziness<\/a>, and blurred vision and can therefore impair your ability to react.\u00a0Do not drive a car or other vehicle, and do not use electric tools or machines if you feel that your ability to react is affected.\u00a0You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with a doctor or pharmacist if you are unsure.<\/p>\n\n\n\n

Tradolan Retard contains tartrazine<\/h2>\n\n\n\n

Tradolan Retard prolonged-release tablets 150 mg and 200 mg contain the dye tartrazine (E 102) which can cause allergic reactions.
<\/a><\/p>\n\n\n\n

How to use Tradolan Retard<\/h2>\n\n\n\n

Always take this medicine as directed by your doctor or pharmacist. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n

Does\u00a0one should be adjusted to the severity of your pain and your pain sensitivity.\u00a0Usually, you should take the lowest\u00a0dose\u00a0that provides pain relief.\u00a0You should not take more than 400 mg of tramadol hydrochloride per day without a doctor’s\u00a0prescription.<\/p>\n\n\n\n

If the doctor has not prescribed anything else, the recommended dose is:<\/p>\n\n\n\n

Adults and young people from the age of 12<\/strong><\/p>\n\n\n\n

Take one Tradolan Retard 100 mg tablet twice daily, preferably in the morning and in the evening (equivalent to 200 mg tramadol hydrochloride per day).<\/p>\n\n\n\n

Your doctor can prescribe a different, more appropriate dosage of the drug if necessary.<\/p>\n\n\n\n

If necessary, the dose can be increased up to 150 mg or 200 mg 2 times daily (equivalent to 300 mg to 400 mg tramadol hydrochloride per day).<\/p>\n\n\n\n

Children<\/strong><\/p>\n\n\n\n

Tradolan Retard should not be given to children under 12 years of age.<\/p>\n\n\n\n

Elderly patients<\/strong><\/p>\n\n\n\n

For elderly patients (over 75 years), it may take longer for tramadol to disappear from the body.\u00a0If this applies to you, your doctor may recommend that you extend the time between\u00a0doses.<\/p>\n\n\n\n

Severe liver or kidney disease ( insufficiency )\/dialysis patients<\/strong><\/p>\n\n\n\n

Patients with severe liver and\/or\u00a0kidney failure\u00a0should not take Tradolan\u00a0Retard.\u00a0If you have mild or moderate liver and\/or\u00a0kidney failure, your doctor may recommend you extend the time between\u00a0doses.<\/p>\n\n\n\n

How and when should you take Tradolan\u00a0Retard?<\/strong><\/p>\n\n\n\n

Tradolan\u00a0Retard\u00a0tablets 150 mg and 200 mg can be divided into two equal\u00a0doses.<\/p>\n\n\n\n

Tradolan Retard tablets should be swallowed whole, not chewed, together with sufficient liquid, preferably in the morning and in the evening. You can take the tablets both on an empty stomach and with meals.<\/p>\n\n\n\n

You should not take Tradolan Retard longer than necessary.<\/p>\n\n\n\n

If you need to be treated for a longer period, your doctor will periodically check whether you should continue to take Tradolan\u00a0Retard\u00a0and at what\u00a0dose.<\/p>\n\n\n\n

If you feel that the effect of Tradolan Retard is too strong or too weak, contact your doctor or pharmacist.<\/a><\/p>\n\n\n\n

If you have used too much Tradolan Retard<\/h2>\n\n\n\n

If you have ingested too much medicine or if, for example, a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n

If you have taken an extra dose by mistake, there will normally be no ill effects. You should take your next dose as prescribed by your doctor. <\/p>\n\n\n\n

After very high\u00a0doses, pupil dilation, vomiting, drop in blood pressure, palpitations, collapse, loss of consciousness,\u00a0coma\u00a0(deep unconsciousness), epileptic seizures, difficulty breathing, and respiratory arrest may occur.\u00a0In these cases, doctors must be called immediately.<\/p>\n\n\n\n

If you forget to take Tradolan Retard<\/h2>\n\n\n\n

If you have forgotten to take the tablets, the pain will likely return.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose, but simply continue taking the tablets as before.<\/p>\n\n\n\n

If you stop taking Tradolan Retard<\/h2>\n\n\n\n

If you interrupt or stop treatment with Tradolan\u00a0Retard\u00a0too soon, the pain will likely return.\u00a0Contact your doctor if you wish to discontinue the treatment due to unwanted effects.<\/p>\n\n\n\n

You should not suddenly stop taking this medicine unless your doctor tells you to. If you want to stop taking your medicine, you should first discuss it with your doctor, especially if you have been taking it for a long time. The doctor will tell you when and how to stop, which can be done by gradually lowering the dose to reduce the risk of developing unnecessary side effects (withdrawal symptoms).<\/p>\n\n\n\n

Patients have felt unwell if they have been treated with tramadol for a long time and then suddenly stopped the treatment.\u00a0They may feel worried, anxiety, nervousness, or become shaky.\u00a0They may be hyperactive, suffer from sleeping difficulties, or have stomach and intestinal disorders.\u00a0Very few people can suffer from panic attacks, hallucinations, and unusual sensations such as\u00a0itching, tingling, numbness, and ringing in the ears (\u00a0tinnitus\u00a0).\u00a0In very rare cases, unusual\u00a0central nervous system\u00a0symptoms have also been observed, such as confusion, delusions, altered personality perception (depersonalization), altered perception of reality (derealization), and persecutory mania (\u00a0paranoia).\u00a0If these symptoms occur after you have finished your treatment with Tradolan\u00a0Retard, you should contact your doctor.<\/p>\n\n\n\n

If you have further questions about this medicine, contact your doctor or pharmacist.f<\/p>\n\n\n\n

Possible side effects<\/h2>\n\n\n\n

Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n

You should see a doctor immediately if you develop symptoms such as a swollen face, tongue, and\/or throat and\/or difficulty swallowing or if you develop hives along with breathing difficulties.<\/p>\n\n\n\n

The most common side effects during treatment with Tradolan Retard are nausea and dizziness, which occur in more than 1 in 10 users.<\/p>\n\n\n\n

Very common<\/strong>  (may affect more than 1 in 10 users): <\/p>\n\n\n\n