{"id":25361,"date":"2022-09-15T07:29:26","date_gmt":"2022-09-15T07:29:26","guid":{"rendered":"https:\/\/zeepedia.com\/?p=25361"},"modified":"2022-09-17T07:34:38","modified_gmt":"2022-09-17T07:34:38","slug":"tradolan","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/tradolan\/","title":{"rendered":"Tradolan – Tramadol hydrochloride uses, dose and side effects"},"content":{"rendered":"\n

50 mg film-coated tablet
tramadol hydrochloride<\/a><\/p>\n\n\n\n

What Tradolan is and what it is used for<\/h2>\n\n\n\n

Tramadol hydrochloride, the active substance in Tradolan, is an analgesic that belongs to the opioid class that acts on the central nervous system. Tramadol hydrochloride acts as a pain reliever by affecting specific nerve cells in the spinal cord and brain.<\/p>\n\n\n\n

Tradolan is used to treat moderate to severe pain.<\/p>\n\n\n\n

Tramadol hydrochloride contained in Tradolan may also be approved to treat other conditions not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions and always follow their instructions.
<\/p>\n\n\n\n

What you need to know before using Tradolan<\/h2>\n\n\n\n

Do not use Tradolan<\/h2>\n\n\n\n

– if you are allergic to tramadol hydrochloride or any of the other ingredients of this medicine (listed in section 6).<\/p>\n\n\n\n

– if you have recently used alcohol, sleeping pills, painkillers, or\u00a0psychopharmaceuticals\u00a0(medicines that affect mood\/mood and emotional life).<\/p>\n\n\n\n

– if you are simultaneously using MAO inhibitors (certain medicines for the treatment of depression) or have taken such medicines in the last 14 days before treatment with Tradolan (see “Other medicines and Tradolan”).<\/p>\n\n\n\n

– if you suffer from epilepsy that is not well controlled with treatment.<\/p>\n\n\n\n

– as a substitute for drug withdrawal.<\/a><\/p>\n\n\n\n

Warnings and precautions<\/h2>\n\n\n\n

Talk to your doctor or pharmacist before using Tradolan.<\/p>\n\n\n\n

Take special care with Tradolan:<\/p>\n\n\n\n

– if you suspect that you are or have been addicted to other painkillers ( opioids ).<\/p>\n\n\n\n

– if you suffer from a reduced level of consciousness (if you feel faint).<\/p>\n\n\n\n

– if you are in a state of shock (cold sweating can be a sign of this).<\/p>\n\n\n\n

– if you have increased pressure in your head (after a skull or brain injury).<\/p>\n\n\n\n

– if you have breathing difficulties.<\/p>\n\n\n\n

– if you are prone to epileptic seizures or convulsions, as the risk of seizures may increase.<\/p>\n\n\n\n

– if you have impaired liver or kidney function.<\/p>\n\n\n\n

– if you suffer from depression and are taking antidepressants as some of them can interact with tramadol (see “Other medicines and Tradolan”).<\/p>\n\n\n\n

Sleep-related breathing disorders<\/p>\n\n\n\n

Tradolan can cause sleep-related breathing disorders such as sleep apnea (breathing pause<\/p>\n\n\n\n

during sleep) and sleep-related\u00a0hypoxemia\u00a0(low oxygen in the blood).\u00a0The symptoms can be breathing pauses during sleep, awakenings during the night due to shortness of breath, difficulty maintaining sleep, or severe drowsiness during the day.\u00a0Contact a doctor if you or someone else notices these symptoms.\u00a0The doctor may consider lowering your\u00a0dose.<\/p>\n\n\n\n

Talk to your doctor or pharmacist if you experience any of the following symptoms while taking Tradolan.\u00a0Extreme fatigue, loss of appetite, severe abdominal pain, nausea, vomiting, or low\u00a0blood pressure.\u00a0This can be a sign of adrenal cortex failure (low levels of\u00a0cortisol\u00a0).\u00a0Contact a doctor if you experience these symptoms.\u00a0The doctor will decide if you need to take hormone replacement<\/p>\n\n\n\n

Epileptic seizures have been reported in patients taking the recommended dose of tramadol. The risk may increase if the dose of tramadol exceeds the recommended upper daily dose (400 mg).<\/p>\n\n\n\n

Please note that Tradolan can cause physical and psychological dependence.\u00a0When Tradolan is taken for a longer period, the effect may decrease and higher\u00a0doses\u00a0may become necessary (\u00a0tolerance development\u00a0).\u00a0Patients with a tendency to drug abuse or who are dependent on drugs will be treated with Tradolan only for short periods and under strict medical supervision.<\/p>\n\n\n\n

Tramadol is converted into the liver by an\u00a0enzyme.\u00a0Some people have a variation of this\u00a0enzyme\u00a0and it can affect different people in different ways.\u00a0Some people may not get enough pain relief, while others are at greater risk of serious\u00a0side effects.\u00a0If you experience any of the following\u00a0side effects, stop taking this medicine and see a doctor immediately: slow or shallow breathing, confusion, sleepiness, small\u00a0pupils, nausea or vomiting, constipation, and poor appetite.<\/p>\n\n\n\n

There is a small risk that you may get a so-called serotonin syndrome, which can occur after taking tramadol in combination with certain antidepressants or tramadol alone. Seek immediate medical attention if you experience any of the symptoms of this serious syndrome (see section 4, \u201cPossible side effects\u201d).<\/p>\n\n\n\n

If you stop taking Tramadol, especially after long-term treatment, your doctor will recommend tapering the dose to reduce withdrawal symptoms.<\/p>\n\n\n\n

Treatment with Tradolan can cause\u00a0caries\u00a0as a result of\u00a0dry mouth.\u00a0The teeth should be cleaned with fluoride<\/a> toothpaste 2 times a day.<\/p>\n\n\n\n

Inform your doctor if one or more of these problems occur during treatment with Tradolan or if they have affected you in the past.<\/p>\n\n\n\n

Children<\/strong><\/p>\n\n\n\n

Tradolan is not suitable for children under 12 years of age.<\/p>\n\n\n\n

Use in children with breathing problems<\/p>\n\n\n\n

Tramadol is not recommended for children with respiratory problems as the symptoms of tramadol poisoning may be worse in these children.<\/a><\/p>\n\n\n\n

Other medicines and Tradolan<\/h2>\n\n\n\n

Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n

Tradolan should not be taken with MAO inhibitors (a type of medicine used to treat depression)<\/p>\n\n\n\n

The pain-relieving effect of Tradolan can be reduced and the duration of action can be shortened, if you simultaneously take other medicines that contain:<\/p>\n\n\n\n

– carbamazepine (for epilepsy )<\/p>\n\n\n\n

– ondansetron<\/a> (for nausea)<\/p>\n\n\n\n

– fluoxetine , paroxetine (for depression). These can also increase the risk of convulsions (see below).<\/p>\n\n\n\n

Concomitant use of Tradolan and sedative drugs or drugs for sleep disorders such as\u00a0benzodiazepines\u00a0or similar drugs increases the risk of drowsiness, breathing difficulties (\u00a0respiratory depression\u00a0),\u00a0and coma,\u00a0and can be life-threatening.\u00a0Because of this, concomitant use should only be considered when other treatment options are not possible.<\/p>\n\n\n\n

If the doctor prescribes Tradolan at the same time as sedative drugs, the dose and duration of treatment must be limited by the doctor.<\/p>\n\n\n\n

Tell the doctor if you are taking any sedative medication and follow the doctor’s dosage recommendations carefully. It may be good to inform friends or relatives to be aware of the signs and symptoms described above. Contact a doctor if you experience any of these symptoms.<\/p>\n\n\n\n

The doctor assesses whether you can use Tradolan and with what\u00a0dose.<\/p>\n\n\n\n

The risk of side effects increases if you:<\/p>\n\n\n\n

– at the same time using sedatives, sleeping pills, other painkillers such as morphine and codeine (also as cough medicine), and alcohol with Tradolan. You may feel drowsy and faint. Tell the doctor if this happens.<\/p>\n\n\n\n

– at the same time taking medicines that can cause convulsions (seizures), for example, certain medicines for depression or mental illness.\u00a0The risk of seizures may increase.\u00a0Your doctor will inform you if Tradolan is suitable for you.<\/p>\n\n\n\n

– are taking certain antidepressants, as Tradolan may interact with these medicines and you may develop serotonin syndrome (see section 4, “Possible side effects”).<\/p>\n\n\n\n

– at the same time taking coumarin-type\u00a0anticoagulants\u00a0(blood-thinning drugs) such as\u00a0warfarin, together with Tradolan.\u00a0The effect of these medicines on the blood’s ability to clot can be affected and bleeding can occur.<\/p>\n\n\n\n

Tramadol with food and drink<\/h2>\n\n\n\n

Food does not affect the effect of Tradolan. Do not drink alcohol when using Tradolan as the side effects of this medicine can be increased.<\/a><\/p>\n\n\n\n

Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n

If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n

Pregnancy<\/p>\n\n\n\n

There is insufficient information on the safety of tramadol use during pregnancy. Therefore, Tradolan should not be used during pregnancy.<\/p>\n\n\n\n

Breast-feeding<\/p>\n\n\n\n

Tramadol is excreted in breast milk.\u00a0You should therefore not take Tradolan more than once during breastfeeding.\u00a0Alternatively, if you take Tradolan more than once, you should stop breastfeeding.<\/p>\n\n\n\n

Fertility<\/p>\n\n\n\n

Experience based on humans does not indicate that tramadol affects female or male\u00a0fertility.<\/p>\n\n\n\n

Driving ability and use of machinery<\/h2>\n\n\n\n

Tramadol can cause drowsiness, dizziness, and blurred vision and can therefore impair your ability to react.\u00a0Do not drive a car or other vehicle, and do not use electric tools or machines if you feel that your ability to react is affected.\u00a0You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with a doctor or pharmacist if you are unsure.
<\/p>\n\n\n\n

How to use Tradolan<\/h2>\n\n\n\n

Always use this medicine as directed by your doctor or pharmacist. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n

Does\u00a0one should be adjusted to the severity of your pain and your pain sensitivity.\u00a0Usually, you should take the lowest\u00a0dose\u00a0that provides pain relief.\u00a0You should not take more than 400 mg of tramadol hydrochloride per day without a doctor’s\u00a0prescription.<\/p>\n\n\n\n

If the doctor has not prescribed anything else, the recommended dose is:<\/p>\n\n\n\n

Adults and young people over 12 years of age<\/em> <\/p>\n\n\n\n

The usual starting dose is 1 tablet.\u00a0If sufficient pain relief is not achieved after 30-60 minutes, another 1 tablet can be taken.<\/p>\n\n\n\n

In acute pain conditions, 2 tablets can be taken as a starting dose.\u00a0Usually, 1-2 tablets 3-4 times per day are sufficient.\u00a0Your doctor can\u00a0prescribe\u00a0a different, more appropriate\u00a0dosage\u00a0of the drug if necessary.<\/p>\n\n\n\n

Elderly patients<\/em><\/p>\n\n\n\n

For elderly patients (over 75 years), it may take longer for tramadol to disappear from the body.\u00a0If this concerns you, your doctor may advise you to extend the time between\u00a0doses.<\/p>\n\n\n\n

Severe liver or kidney failure ( insufficiency )\/dialysis patients<\/em><\/p>\n\n\n\n

Patients with severe liver and\/or\u00a0kidney failure\u00a0should not take Tradolan.\u00a0If you have mild or moderate liver and\/or\u00a0kidney failure, your doctor may recommend you extend the time between\u00a0doses.<\/p>\n\n\n\n

How and when should you take Tradolan?<\/h2>\n\n\n\n

The tablets should be swallowed with plenty of liquid<\/a> (e.g. \u00bd glass of water). The tablets should not be chewed. Tradolan tablets can be taken independently of a meal.<\/p>\n\n\n\n

You should not take Tradolan for longer than necessary.<\/p>\n\n\n\n

If you need to be treated for a longer period, your doctor will periodically check whether you should continue to take Tradolan and at what\u00a0dose.<\/p>\n\n\n\n

If you feel that the effect of Tradolan is too strong or too weak, contact your doctor or pharmacist.<\/a><\/p>\n\n\n\n

If you have taken too much Tradolan<\/h2>\n\n\n\n

If you have ingested too much medicine or if, for example, a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n

After very high\u00a0doses, the following symptoms may occur: pupil dilation, vomiting, drop in blood pressure, heart palpitations, collapse, loss of consciousness\/coma (deep unconsciousness) with fatal outcome, epileptic seizures, breathing difficulties, and respiratory arrest.\u00a0In these cases, doctors must be called immediately.<\/p>\n\n\n\n

If you forget to take Tradolan<\/h2>\n\n\n\n

If you have forgotten to take the tablets, the pain will likely return.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose, but simply continue taking the tablets as before.<\/p>\n\n\n\n

If you stop taking Tradolan<\/h2>\n\n\n\n

If you stop or stop treatment with Tradolan too soon, the pain is likely to come back. Contact your doctor if you wish to discontinue the treatment due to unwanted effects.<\/p>\n\n\n\n

You should not suddenly stop taking this medicine unless your doctor tells you to. If you want to stop taking your medicine, you should first discuss it with your doctor, especially if you have been taking it for a long time. The doctor will tell you when and how to stop, which can be done by gradually lowering the dose to reduce the risk of developing unnecessary side effects (withdrawal symptoms).<\/p>\n\n\n\n

Patients may feel unwell if they have been treated with tramadol for a long time and then suddenly stop the treatment.\u00a0They may feel worried, anxious, nervous, or become shaky.\u00a0They may be hyperactive, suffer from sleeping difficulties, or have stomach and intestinal disorders.\u00a0Very few people can suffer from panic attacks, hallucinations, and unusual sensations such as\u00a0itching, tingling, numbness, and ringing in the ears (\u00a0tinnitus\u00a0).\u00a0In very rare cases, unusual\u00a0central nervous system\u00a0symptoms have also been observed, such as confusion, delusions, altered personality perception (depersonalization), altered perception of reality (derealization), and persecutory mania (\u00a0paranoia).\u00a0If these symptoms occur after you have finished your treatment with Tradolan, you should contact your doctor.<\/p>\n\n\n\n

If you have any further questions about this medicine, ask your doctor or pharmacist.<\/a><\/p>\n\n\n\n

Possible side effects<\/h2>\n\n\n\n

Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n

You should see a doctor immediately if you experience any of the following symptoms:<\/p>\n\n\n\n

– swollen face, tongue, and\/or throat and\/or difficulty swallowing or if you get hives along with breathing difficulties (may affect up to 1 in 1,000 users).<\/p>\n\n\n\n

–\u00a0respiratory depression.\u00a0If the recommended\u00a0dose\u00a0is significantly exceeded, or if any medicine that lowers brain function is taken at the same time, the breathing rate may decrease (may affect up to 1 in 1,000 users).<\/p>\n\n\n\n

– serious skin reactions such as toxic epidermal necrolysis and Steven Johnson syndrome) (may affect up to 1 in 10,000 users)<\/p>\n\n\n\n

Very common<\/strong> (may affect more than 1 in 10 users):<\/p>\n\n\n\n