{"id":25355,"date":"2022-09-15T07:25:52","date_gmt":"2022-09-15T07:25:52","guid":{"rendered":"https:\/\/zeepedia.com\/?p=25355"},"modified":"2022-09-17T07:34:59","modified_gmt":"2022-09-17T07:34:59","slug":"tractocile","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/tractocile\/","title":{"rendered":"Tractocile &#8211; Atosiban uses, dose and side effects"},"content":{"rendered":"\n<p>6.75 mg\/0.9 ml&nbsp;solution&nbsp;<\/p>\n\n\n\n<p>for injection<br>atosiban<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Tractocile is and what it is used for<\/h2>\n\n\n\n<p>Tractocile contains atosiban.&nbsp;Tractocile can be used to delay a premature birth of your baby.&nbsp;Tractocile is used in adult pregnant women from week 24 to week 33 of pregnancy.<\/p>\n\n\n\n<p>Tractocile works by making the contractions in the uterus less strong.&nbsp;It also makes contractions less frequent.&nbsp;This happens by&nbsp;inhibiting&nbsp;the effect of a natural&nbsp;hormone&nbsp;in the body called&nbsp;oxytocin&nbsp;, which causes the uterus to contract.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Tractocile<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Tractocile<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if your pregnancy is less than 24 weeks<\/li><li>if your pregnancy exceeds 33 weeks<\/li><li>if the water has broken (&nbsp;premature&nbsp;rupture of membranes) after 30 weeks of pregnancy or more<\/li><li>if your unborn child (fetus) has an abnormal heart rate<\/li><li>if you have uterine bleeding and the doctor wants the baby to be born right away<\/li><li>if you have something called &#8220;severe pre-eclampsia&#8221; and the doctor wants the baby to be born right away.&nbsp;Severe pre-&nbsp;eclampsia&nbsp;means high&nbsp;blood pressure&nbsp;, fluid retention and\/or egg whites in the urine.<\/li><li>if you have something called &#8220;eclampsia&#8221; which is similar to &#8220;severe pre-eclampsia&#8221; but you also get cramps.&nbsp;This means that the baby must be born immediately.<\/li><li>if your unborn child has died<\/li><li>if you have an&nbsp;infection&nbsp;or suspected&nbsp;infection&nbsp;in the uterus<\/li><li>if the&nbsp;placenta&nbsp;covers the birth canal<\/li><li>if the&nbsp;placenta&nbsp;is about to detach from the uterine wall<\/li><li>if you or your unborn child have other conditions where continuing the pregnancy is considered risky<\/li><li>if you are allergic to atosiban or any of the other ingredients of this medicine (listed in section 6)<\/li><\/ul>\n\n\n\n<p>Do not use Tractocile if any of the above applies to you.&nbsp;If you are not sure, talk to your doctor, midwife or pharmacist before receiving Tractocile.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor, midwife or pharmacist before receiving Tractocile:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you think your water has broken (&nbsp;premature&nbsp;rupture of membranes)<\/li><li>if you have kidney or liver problems<\/li><li>if you are between 24 and 27 weeks pregnant<\/li><li>if you are pregnant with more than one child<\/li><li>if the contractions return, the Tractocile treatment can be repeated 3 more times<\/li><li>if your unborn child is small in relation to the length of the pregnancy<\/li><li>the uterus may be less likely to contract when your baby is born, this may cause bleeding<\/li><li>if you are pregnant with more than one child and\/or are receiving medicines to delay the premature birth of your child such as blood pressure lowering medicines.&nbsp;This can increase the risk of&nbsp;pulmonary edema&nbsp;(&nbsp;accumulation&nbsp;of fluid in the lungs).<\/li><\/ul>\n\n\n\n<p>If any of the above apply to you (or if you are not sure), talk to your doctor, midwife or pharmacist before receiving Tractocile.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>There is no experience with the use of Tractocile in women under 18 years of age.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Tractocile<\/h2>\n\n\n\n<p>Tell your doctor, midwife or pharmacist if you are taking, have recently taken or might take any other medicines.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant and breast-feeding a previous child, you should stop breast-feeding while you are receiving Tractocile.<a><\/a><br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Tractocile<\/h2>\n\n\n\n<p>Tractocile is given in hospital by a doctor, midwife or nurse.&nbsp;They determine how much you need.&nbsp;They will also ensure that the solution is clear and free of particles.<\/p>\n\n\n\n<p>Tractocile is given into a vein (&nbsp;intravenously&nbsp;) in three stages:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the first&nbsp;injection&nbsp;one of 6.75 mg in 0.9 ml is slowly injected into a vein over one minute<\/li><li>then a&nbsp;continuous&nbsp;infusion&nbsp;(drip) is given at a&nbsp;dose&nbsp;of 18 mg\/hour for 3 hours<\/li><li>then another&nbsp;continuous&nbsp;infusion&nbsp;(drip) is given at a&nbsp;dose&nbsp;of 6 mg\/hour for up to 45 hours or until uterine contractions subside.<\/li><\/ul>\n\n\n\n<p>The treatment should not exceed 48 hours in total.<\/p>\n\n\n\n<p>Tractocile can be used again, should the contractions return.&nbsp;Treatment with Tractocile can be repeated up to three times.<\/p>\n\n\n\n<p>During treatment with Tractocile, your contractions and fetal heart rate may be monitored.<\/p>\n\n\n\n<p>More than three additional treatments should not be given during a pregnancy.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects&nbsp;, although not everybody gets them.<\/p>\n\n\n\n<p>The&nbsp;side effects&nbsp;seen in the mother are generally mild.&nbsp;There are no known&nbsp;side effects&nbsp;in the unborn or the newborn child.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;can occur with this medicine:<\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(affects more than 1 in 10 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Nausea<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(affects less than 1 in 10 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache.<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/dizziness\/\">Dizziness<\/a>.<\/li><li>Hot flashes.<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/stomach-disease-diarrhea-and-vomiting\/\">Vomiting<\/a>.<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/palpitation\/\">Palpitation<\/a>.<\/li><li>Low&nbsp;blood pressure&nbsp;.&nbsp;Symptoms may include dizziness or feeling intoxicated.<\/li><li>Injection site reaction.<\/li><li>High <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/diabetes-type-1\/\">blood sugar<\/a>.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(affects less than 1 in 100 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">Fever<\/a>.<\/li><li>Insomnia.<\/li><li>Itching&nbsp;.<\/li><li>Rash.<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(affects less than 1 in 1,000 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The uterus may be less likely to contract when your baby is born.&nbsp;This can cause bleeding.<\/li><li>Allergic reactions<\/li><\/ul>\n\n\n\n<p>You may experience shortness of breath or&nbsp;pulmonary edema&nbsp;(&nbsp;accumulation&nbsp;of fluid in the lungs), especially if you are pregnant with more than one child and\/or are receiving medicines that may delay the premature birth of your baby such as blood pressure lowering medicines.<\/p>\n\n\n\n<p>If you experience&nbsp;side effects&nbsp;, talk to your doctor, midwife or pharmacist.&nbsp;This also applies to any&nbsp;side effects&nbsp;that are not mentioned in this information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Tractocile<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Use before the expiry date stated on the label after &#8220;Exp.&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Store in a refrigerator (2\u00b0C &#8211; 8\u00b0C).<\/li><li>Store in the original packaging.&nbsp;Light sensitive.<\/li><li>Once a&nbsp;vial&nbsp;has been opened, the product must be used immediately.<\/li><li>Do not use this medicine if you observe particles and discoloration before&nbsp;administration&nbsp;.<\/li><\/ul>\n\n\n\n<p><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is atosiban.<\/li><li>Each&nbsp;vial&nbsp;of Tractocile 6.75 mg\/0.9 ml&nbsp;solution for injection&nbsp;contains atosiban acetate corresponding to 6.75 mg of atosiban in 0.9 ml.<\/li><li>Other ingredients are mannitol,&nbsp;hydrochloric acid&nbsp;and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Tractocile 6.75 mg\/0.9 ml&nbsp;solution for injection&nbsp;is a clear, colorless solution without particles.&nbsp;One pack contains a&nbsp;vial&nbsp;with 0.9 ml of solution.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder:<\/em><\/p>\n\n\n\n<p>Ferring Pharmaceuticals A\/S<\/p>\n\n\n\n<p>Amager Strandvej 405<\/p>\n\n\n\n<p>2770 Kastrup<\/p>\n\n\n\n<p>Denmark<\/p>\n\n\n\n<p>Phone: +45 88 33 88 34<\/p>\n\n\n\n<p><em>Manufacturer:<\/em><\/p>\n\n\n\n<p>Ferring GmbH<\/p>\n\n\n\n<p>Wittland 11<\/p>\n\n\n\n<p>D-24109 Kiel<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>Contact the representative of the Marketing Authorization Holder if you would like to know more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><th scope=\"col\"><\/th><th scope=\"col\"><\/th><\/tr><tr><td><strong>Belgi\u00eb\/Belgique\/Belgien<\/strong>Ferring NWTel\/Tel: +32- 53 72 92 00ferringnvsa@ferring.be<\/td><td><strong>Lithuania<\/strong>CentralPharma Communication UABTel: +370 5 243 0444centralpharma@centralpharma.lt<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Farmont EOODPhone: +359 2 807 5022farmont@farmont.bg<\/td><td><strong>Luxembourg\/Luxembourg<\/strong>Ferring NWBelgique\/BelgiumTel\/Tel: +32 53 72 92 00ferringnvsa@ferring.be<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Ferring Pharmaceuticals CZ sroPhone: +420 234 701 333cz1-info@ferring.com<\/td><td><strong>Magyarorsz\u00e1g<\/strong>Ferring Magyarorsz\u00e1g Gy\u00f3gyszerkereskedelmi Kft.Phone: +36 1 236 3800ferring@ferring.hu<\/td><\/tr><tr><td><strong>Denmark<\/strong>Ferring L\u00e6gemidler A\/SPhone: +45 88 16 88 17<\/td><td><strong>Malta<\/strong>EJ Busuttil Ltd.Phone: +356 21447184info@ejbusuttil.com<\/td><\/tr><tr><td><strong>Deutschland<\/strong>Ferring Arzneimittel GmbHPhone: +49 431 5852 0info-service@ferring.de<\/td><td><strong>The Netherlands<\/strong>Ferring BVPhone: +31 235680300infoNL@ferring.com<\/td><\/tr><tr><td><strong>Estonia<\/strong>CentralPharma Communication O\u00dc Tel: +372 601 5540centralpharma@centralpharma.ee<\/td><td><strong>Norway<\/strong>Ferring Legemidelr ASPhone: +47 22 02 08 80mail@oslo.ferring.com<\/td><\/tr><tr><td><strong>Greece<\/strong>Ferring \u0395\u03bb\u03bb\u03ac\u03c2 \u039c\u0395\u03a0\u0395Tel: +30 210 68 43 449<\/td><td><strong>Austria<\/strong>Ferring Arzneimittel Ges.mbHPhone: +43 1 60 8080office@ferring.at<\/td><\/tr><tr><td><strong>Spain<\/strong>Ferring SAUPhone: +34 91 387 70 00registros@ferring.com<\/td><td><strong>Polish<\/strong>Ferring Pharmaceuticals Poland Sp.&nbsp;z o. oPhone: +48 22 246 06 80PL0-Recepcja@ferring.com<\/td><\/tr><tr><td><strong>France<\/strong>Ferring SASPhone: +33 1 49 08 67 60information.medicale@ferring.com<\/td><td><strong>Portugal<\/strong>Ferring Portuguesa \u2013 Produtos Farmac\u00eauticos, Sociedade Unipessoal, Lda.Phone: +351 21 940 51 90<\/td><\/tr><tr><td><strong>Hrvatska<\/strong>Clinres farmacija dooPhone: +385 1 2396 900<\/td><td><strong>Romania<\/strong>Ferring Pharmaceuticals Romania SRLPhone: +40 356 113 270<\/td><\/tr><tr><td><strong>Ireland<\/strong>Ferring Ireland Ltd.Phone: +353 1 4637355EnquiriesIrelandMailbox@ferring.com<\/td><td><strong>Slovenija<\/strong>SALUS, Veletrgovina, dooPhone: +386 1 5899 179regulatory@salus.si<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hf.Telephone: +354 535 70 00<\/td><td><strong>Slovenian Republic<\/strong>Ferring Slovakia s.r.oPhone: +421 2 5441 1847SK0-Recepcia@ferring.com<\/td><\/tr><tr><td><strong>Italy<\/strong>Ferring S.p.APhone: +3902 640 00 11<\/td><td><strong>Finland\/Finland<\/strong>Ferring L\u00e4\u00e4kkeet OyPhone\/Tel: +358 207 401 440info@ferring.fi<\/td><\/tr><tr><td><strong>Cyprus<\/strong>A. Potamitis Medicare LtdPhone: +357 22583333a.potamitismedicare@cytanet.com.cy<\/td><td><strong>Sweden<\/strong>Ferring L\u00e4kemedel ABPhone: +46 40 691 69 00info@ferring.se<\/td><\/tr><tr><td><strong>Latvia<\/strong>CentralPharma Communication Tel: +371 674 50497 centralpharma@centralpharma.lv<\/td><td><strong>United Kingdom (Northern Ireland)<\/strong>Ferring Ireland Ltd.Phone: +353 1 4637355EnquiriesIrelandMailbox@ferring.com<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Tractocile contains atosiban.\u00a0Tractocile can be used to delay a premature birth of your baby.\u00a0Tractocile is used in adult pregnant women from week 24 to week 33 of pregnancy.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[9759,26220,26218,26224,26219,26222,9769,9760,26221,26223],"class_list":["post-25355","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-atosiban","tag-atosiban-side-effects","tag-benefits-of-atosiban","tag-benefits-of-tractocile","tag-tractocile","tag-tractocile-side-effects","tag-what-atosiban-is-used-for","tag-what-is-atosiban","tag-what-is-tractocile","tag-what-tractocile-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25355","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=25355"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25355\/revisions"}],"predecessor-version":[{"id":25429,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25355\/revisions\/25429"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=25355"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=25355"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=25355"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}