{"id":25213,"date":"2022-09-12T07:44:10","date_gmt":"2022-09-12T07:44:10","guid":{"rendered":"https:\/\/zeepedia.com\/?p=25213"},"modified":"2022-09-13T06:56:58","modified_gmt":"2022-09-13T06:56:58","slug":"topimax","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/topimax\/","title":{"rendered":"Topimax &#8211; Topiramate uses, dose and side effects"},"content":{"rendered":"\n<p>25 mg, 50 mg, 100 mg, 200 mg&nbsp;film-coated tablets<br>topiramate<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Topimax is and what it is used for<\/h2>\n\n\n\n<p>Topimax belongs to a group of medicines called anti-epileptic medicines.&nbsp;It is used:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>alone for the treatment of epileptic seizures in adults and children over 6 years of age<\/li><li>together with other medicines for the treatment of epileptic seizures in adults and children 2 years of age or older<\/li><li>to prevent migraine headaches in adults<\/li><\/ul>\n\n\n\n<p>The topiramate contained in Topimax may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Topimax<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Topimax:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to topiramate or any of the other ingredients of this medicine (listed in section 6).<\/li><li>Migraine prevention: if you are pregnant or if you are a woman of&nbsp;childbearing&nbsp;age unless you are using an effective contraceptive method (see section &#8220;Pregnancy and breast-feeding&#8221; for further information).&nbsp;Talk to your doctor about the best method of birth control to use while taking Topimax.<\/li><\/ul>\n\n\n\n<p>If you are not sure if the above applies to you, talk to your doctor or pharmacist before using Topimax.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Topimax if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have kidney problems, especially\u00a0kidney stones, or receive kidney dialysis<\/li><li>have had abnormalities in blood or body fluids (metabolic\u00a0acidosis\u00a0)<\/li><li>have liver problems<\/li><li>have eye problems, especially\u00a0glaucoma<\/li><li>have growth problems<\/li><li>is on a high-fat diet (ketogenic diet)<\/li><li>taking Topimax to treat\u00a0epilepsy\u00a0and you are pregnant or a woman of\u00a0childbearing potential\u00a0(see section \u201cPregnancy and breast-feeding\u201d for further information)<\/li><\/ul>\n\n\n\n<p>If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before using Topimax.<\/p>\n\n\n\n<p>You mustn&#8217;t stop taking your medication without first consulting your doctor.<\/p>\n\n\n\n<p>You should also talk to your doctor before taking any medicine containing topiramate, which is given to you as an alternative to Topimax.<\/p>\n\n\n\n<p>You may lose weight if you use Topimax, so your weight should be checked regularly while using this medicine.&nbsp;If you lose too much weight or if a child using this medicine does not gain enough weight, consult your doctor.<\/p>\n\n\n\n<p>A small number of people treated with anti-epileptic drugs\u00a0such as Topimax have also had thoughts of harming themselves or committing suicide.\u00a0If you ever have these thoughts, contact your doctor immediately.<\/p>\n\n\n\n<p>Topimax can cause serious skin reactions.&nbsp;Tell your doctor immediately if you get a rash and\/or blisters (see also section 4 \u201cPossible side effects\u201d).<\/p>\n\n\n\n<p>Topimax can rarely cause high levels of ammonia in the blood (shown in blood tests).&nbsp;This can lead to altered brain function, especially if you are also taking a medicine called&nbsp;valproic acid&nbsp;or sodium valproate.&nbsp;As this can be a serious condition, tell your doctor immediately if you experience the following symptoms (see also section 4 \u201cPossible side effects\u201d):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have difficulty thinking, remembering information, or solving problems<\/li><li>is less alert or attentive<\/li><li>feeling very sleepy with low energy<\/li><\/ul>\n\n\n\n<p>At higher&nbsp;doses&nbsp;of Topimax, the risk of developing these symptoms may increase.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Topimax<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0Topimax and some other medicines can interact.\u00a0Sometimes the\u00a0dose\u00a0of one of your medicines or Topimax needs to be adjusted.<\/p>\n\n\n\n<p>You must especially inform the doctor or pharmacist if you are taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>other drugs that cause impaired or impaired thinking ability, concentration, or muscle coordination (e.g. drugs with a depressing effect on the\u00a0central nervous system\u00a0such as muscle relaxants and sedatives)<\/li><li>birth control pills.\u00a0Topimax can make your\u00a0birth control pills\u00a0less effective.\u00a0Talk to your doctor about the best method of birth control to use while taking Topimax.<\/li><\/ul>\n\n\n\n<p>Tell your doctor if your menstrual bleeding changes while you are taking&nbsp;the pill&nbsp;and Topimax.<\/p>\n\n\n\n<p>For a list of all medicines that you take.\u00a0Show this list to your doctor and pharmacist before starting a new medicine.<\/p>\n\n\n\n<p>Other medicines that you should discuss with your doctor or pharmacist include other medicines for\u00a0epilepsy,\u00a0risperidone, lithium,\u00a0hydrochlorothiazide,\u00a0metformin\u00a0, pioglitazone, glibenclamide, amitriptyline, propranolol,\u00a0diltiazem,\u00a0venlafaxine, flunarizine,\u00a0St. John&#8217;s wort (\u00a0Hypericum perforatum\u00a0) (a (traditional) herbal medicines used to treat depression), blood thinner\u00a0warfarin.<\/p>\n\n\n\n<p>If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before using Topimax.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Topimax with food and drink<\/h2>\n\n\n\n<p>You can take Topimax with or without food.&nbsp;Drink plenty of fluids during the day to prevent&nbsp;kidney stones&nbsp;when you take Topimax.&nbsp;You should avoid drinking alcohol while taking Topimax.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Migraine Prevention:<\/p>\n\n\n\n<p>Topimax can harm an unborn baby.\u00a0You must not use Topimax if you are pregnant.\u00a0You must not use Topimax prophylactically against\u00a0migraines\u00a0if you are a woman of\u00a0childbearing\u00a0age unless you use an effective contraceptive method.\u00a0Talk to your doctor about which method of contraception is best and if Topimax is right for you.\u00a0A pregnancy test must be done before starting treatment with Topimax.<\/p>\n\n\n\n<p>Treatment of epilepsy:<\/p>\n\n\n\n<p>If you are a woman of&nbsp;childbearing&nbsp;age, you should talk to your doctor about other treatment options instead of Topimax.&nbsp;If the decision is to use Topimax, you must use an effective method of contraception.&nbsp;Talk to your doctor about the best method of birth control while taking Topimax.&nbsp;A pregnancy test must be done before starting treatment with Topimax.<\/p>\n\n\n\n<p>Talk to your doctor if you are planning to become pregnant.<\/p>\n\n\n\n<p>As with other anti-epileptic drugs\u00a0, there is a risk of harm to the unborn child if Topimax is used during pregnancy.\u00a0Make sure you fully understand the risks and benefits of using Topimax for\u00a0epilepsy\u00a0during pregnancy.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you take Topimax during pregnancy, the baby is at a higher risk of congenital malformations, especially cleft lip and\u00a0palate.\u00a0Newborn boys can also have a misshapen penis (hypospadias).\u00a0These malformations can develop early in pregnancy, even before you know you are pregnant.<\/li><li>If you take Topimax during pregnancy, your baby may be smaller than expected at birth.\u00a0Talk to your doctor if you have any questions about this risk during pregnancy.<\/li><li>For your condition, there may be other drug treatments that have a lower risk of malformations.<\/li><li>Tell your doctor immediately if you become pregnant while taking Topimax.\u00a0You and the doctor decide whether you should continue taking Topimax during pregnancy.<\/li><\/ul>\n\n\n\n<p>Breast-feeding<\/p>\n\n\n\n<p>The active substance in Topimax (topiramate) is excreted in human breast milk.&nbsp;Effects in breastfed infants of treated mothers have been observed and include diarrhea, drowsiness, irritability, and poor weight gain.&nbsp;Therefore, your doctor will discuss with you whether you should refrain from breastfeeding or refrain from treatment with Topimax.&nbsp;The doctor will take into account the importance of the medicine for the mother and the risk to the child.<\/p>\n\n\n\n<p>Mothers who are breastfeeding while taking Topimax must inform the doctor as soon as possible if the baby experiences anything unusual.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Dizziness, fatigue, and vision problems may occur during treatment with Topimax.\u00a0Do not drive or use any tools or machinery without first talking to your doctor.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Topimax contains lactose<\/h2>\n\n\n\n<p>If you have an intolerance to some sugars, you should contact your doctor before taking this medicine.<\/p>\n\n\n\n<p><strong>Other ingredients<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;of sodium&nbsp;per tablet, i.e. it is almost &#8220;sodium-free&#8221;.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Topimax<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor will usually let you start with a low\u00a0dose\u00a0of Topimax and slowly increase the\u00a0dose\u00a0until you find the best\u00a0dose\u00a0for you.<\/li><li>Topimax tablets should be swallowed whole.\u00a0Avoid chewing the tablets as they may leave a bitter taste.<\/li><li>Topimax can be taken before, during, or after a meal.\u00a0Drink plenty of fluids during the day to prevent\u00a0kidney stones\u00a0from forming when you take Topimax.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Topimax<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>See a doctor immediately.\u00a0Take the medicine package with you.<\/li><li>You may feel sleepy, tired, or less alert, lack coordination, have difficulty speaking and concentrating, have double or blurred vision, feel dizzy due to low\u00a0blood pressure, feel depressed or agitated, or have stomach pains or seizures.<\/li><\/ul>\n\n\n\n<p>Overdose can occur if you take other medicines together with Topimax.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Topimax<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take a\u00a0dose, take it as soon as you remember.\u00a0If it is almost time for the next\u00a0dose, skip the missed\u00a0dose\u00a0and continue as usual.\u00a0If you miss two or more\u00a0doses, contact your doctor.<\/li><li>Do not take a double\u00a0dose\u00a0(two\u00a0doses\u00a0at the same time) to make up for a missed\u00a0dose.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Topimax<\/h2>\n\n\n\n<p>Do not stop taking this medicine unless your doctor tells you to.&nbsp;Your symptoms may return.&nbsp;If your doctor decides to stop treatment with this medicine, the&nbsp;dose&nbsp;can be gradually reduced over a few days.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Tell your doctor or see a doctor immediately if you experience the following side effects:<\/strong><\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 in 10 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Depression (new or worsening)<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Seizures<\/li><li>Anxiety, irritability, mood changes, confusion, disorientation<\/li><li>Difficulty concentrating, impaired thinking, memory loss, memory problems (new, sudden change, or increased severity)<\/li><li>Kidney stones, frequent or painful urination<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Increased acidity of the blood (may cause troubled breathing including shortness of breath, loss of appetite, nausea, vomiting, excessive tiredness, and fast or irregular heartbeat)<\/li><li>Decreased or lost ability to sweat (especially in young children exposed to high temperatures)<\/li><li>Have thoughts of serious self-harm, attempt to cause serious self-harm<\/li><li>Loss of part of the field of\u00a0vision\u00a0et<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 users)<\/strong>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Glaucoma\u00a0is a blockage of fluid in the eye and causes increased pressure in the eye, pain, or reduced vision<\/li><li>Having difficulty thinking, remembering information, or solving problems, being less alert or attentive, and feeling very sleepy with low energy \u2013 these symptoms may be a sign of high levels of ammonia in the blood (hyperammonemia) which can lead to altered brain function (hyperammonemia\u00a0encephalopathy\u00a0)<\/li><li>Serious skin reactions such as\u00a0Stevens-Johnson syndrome\u00a0or\u00a0toxic epidermal necrolysis\u00a0which may appear as a rash with or without blisters.\u00a0Skin irritation, sores, or swelling in the mouth, throat, nose, eyes, and around the genitals.\u00a0The skin rash can develop into serious widespread skin damage (skin detachment of the outer skin layers and superficial mucous membranes) with life-threatening consequences.<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurring in an unknown number of users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/eye-inflammation-in-children\/\">Eye inflammation<\/a> (\u00a0uveitis\u00a0) with symptoms such as\u00a0redness\u00a0in the eye, pain, sensitivity to light, watery eyes, small dots in the\u00a0field\u00a0of vision, or blurred vision.<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;include the following.&nbsp;If they get worse, contact your doctor or pharmacist:<\/strong><\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 in 10 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Stuffy, runny nose, or <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sore-throat\/\">sore throat<\/a><\/li><li>Tingling, pain, and\/or numbness in various body parts<\/li><li>Drowsiness, fatigue<\/li><li>Dizziness<\/li><li>Nausea, diarrhea<\/li><li>Weight loss<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Anemia\u00a0(low blood count)<\/li><li>Allergic reactions (such as skin rash,\u00a0redness,\u00a0itching, facial swelling, hives)<\/li><li>Loss of appetite decreased appetite<\/li><li>Aggression, excitement, anger, abnormal behavior<\/li><li>Difficulty falling asleep or staying asleep<\/li><li>Problems with speech or speech difficulties, slurred speech<\/li><li>Clumsiness or lack of coordination, feeling unsteady walking<\/li><li>Decreased ability to complete routine tasks<\/li><li>Decreased, loss of, or nonexistent sense of taste<\/li><li>Involuntary tremors or shaking, rapid uncontrolled eye movements<\/li><li>Visual disturbances such as <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/distinction-and-double-vision-in-adults\/\">double vision<\/a>, blurred vision, reduced\u00a0visual acuity, difficulty focusing<\/li><li>Feeling of dizziness (\u00a0vertigo\u00a0), ringing in the ears, pain in the ears<\/li><li>Respiratory distress<\/li><li>Cough<\/li><li>Nosebleed<\/li><li>Fever, feeling unwell, weakness<\/li><li>Vomiting, constipation, abdominal pain or discomfort, indigestion, stomach or intestinal infection<\/li><li>Dry mouth<\/li><li>Hair loss<\/li><li>Itching<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">Joint pain<\/a> or swelling, muscle cramps or twitching, muscle pain or weakness, chest pain<\/li><li>Weight gain<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Decreased number of\u00a0platelets\u00a0(\u00a0blood cells\u00a0that help stop bleeding), decreased number of\u00a0white blood cells\u00a0that help protect you against\u00a0infection, decreased\u00a0potassium\u00a0in the blood<\/li><li>Increased liver enzymes, increased\u00a0eosinophils\u00a0(a type of\u00a0white blood cell\u00a0) in the blood<\/li><li>Swollen\u00a0glands\u00a0in the neck, armpit, or groin<\/li><li>Increased appetite<\/li><li>Elevated mood<\/li><li>Hearing, seeing, or feeling things that are not there, severe mental disorder (\u00a0psychosis\u00a0)<\/li><li>Not showing and\/or feeling emotions, unusual suspiciousness, panic attack<\/li><li>Reading, speaking, and writing difficulties<\/li><li>Restlessness, overactivity<\/li><li>Difficulty thinking reduced alertness or attention<\/li><li>Reduced or slow body movements, involuntary abnormal or repetitive muscle movements<\/li><li>Fainting<\/li><li>Abnormal or reduced sensation<\/li><li>Impaired, distorted, or no sense of smell<\/li><li>Unusual feeling or sensation that may precede a\u00a0migraine\u00a0or a certain type of attack<\/li><li>Dry eyes, light sensitivity, involuntary eyelid twitching, watery eyes<\/li><li>Impaired or lost hearing, loss of hearing in one ear<\/li><li>Slow or irregular heartbeat, feeling like your heart is pounding in your chest<\/li><li>Low\u00a0blood pressure\u00a0when standing (so some people taking Topimax may feel weak, dizzy, or may faint when standing or sitting up suddenly)<\/li><li>Redness, feeling of warmth<\/li><li>Pancreatitis\u00a0(\u00a0inflammation\u00a0of the pancreas)<\/li><li>Gas, heartburn, fullness or bloating,<\/li><li>Bleeding gums, increased salivation, drooling, bad breath<\/li><li>Intake of abnormally large amounts of fluid, increased thirst<\/li><li>Discolored skin<\/li><li>Muscle stiffness, pain in the side<\/li><li>Blood in the urine,\u00a0incontinence\u00a0(lack of control) of urine, urge to urinate, pain in the side or kidney pain<\/li><li>Difficulty getting or keeping\u00a0an erection, sexual\u00a0dysfunction<\/li><li>Flu-like symptoms<\/li><li>Cold fingers and toes<\/li><li>Feeling of intoxication<\/li><li>Learning problems<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Abnormally elevated mood<\/li><li>Unconsciousness<\/li><li>Blindness in one eye, temporary blindness,\u00a0night blindness<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/visual-impairment\/\">Visual impairment<\/a><\/li><li>Swelling in and around the eyes<\/li><li>Numbness, tingling, and discoloration (white, blue, then red) in fingers and toes when exposed to cold<\/li><li>Liver inflammation, liver failure<\/li><li>The abnormal smell on the skin<\/li><li>Discomfort in arms or legs<\/li><li>Kidney disease<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurring in an unknown number of users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Maculopathy\u00a0is a disease of the\u00a0macula, the small spot on the retina where vision is sharpest.\u00a0You should see a doctor if you notice a change or deterioration in your vision<\/li><\/ul>\n\n\n\n<p><strong>Children<\/strong><\/p>\n\n\n\n<p>Side effects&nbsp;in children are generally similar to those seen in adults, but the following&nbsp;side effects&nbsp;may be more common in children than in adults:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Concentration problems<\/li><li>Increased acidity in the blood<\/li><li>Have thoughts of serious self-harm<\/li><li>Fatigue<\/li><li>Decreased or increased appetite<\/li><li>Aggression, abnormal behavior<\/li><li>Difficulty falling asleep or staying asleep<\/li><li>The feeling of unsteady gait<\/li><li>The feeling of not feeling well<\/li><li>Decreased\u00a0potassium\u00a0in the blood<\/li><li>Not showing and\/or feeling emotions<\/li><li>Watery eyes<\/li><li>Slow or irregular heartbeats.<\/li><\/ul>\n\n\n\n<p>Other&nbsp;side effects&nbsp;that may occur in children are:<\/p>\n\n\n\n<p><strong>Common (&nbsp;<\/strong><strong>may affect&nbsp;<\/strong><strong>up to 1 in 10 users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness<\/li><li>Vomiting<\/li><li>Fever<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Increased&nbsp;eosinophils&nbsp;(a type of&nbsp;white blood cell&nbsp;) in the blood<\/li><li>Overactivity<\/li><li>Feeling of warmth<\/li><li>Learning problems.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How Topimax should be stored<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the printed package\/can\/carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Blister: Store at a maximum of 25\u00b0C.&nbsp;Store in the original packaging.&nbsp;Moisture sensitive.&nbsp;<\/p>\n\n\n\n<p>Can: Store at a maximum of 25\u00b0C.&nbsp;Store in the original packaging.&nbsp;Close the jar well.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is topiramate.<\/li><li>Each Topimax tablet contains 25, 50, 100, or 200 mg of topiramate.<\/li><li>Other ingredients are:<ul><li>tablet core:\u00a0lactose monohydrate, pregelatinized maize starch, microcrystalline cellulose, sodium starch glycolate (type A), magnesium stearate<\/li><li>film coating: OPADRY\u00ae, white, yellow, pink\u00a01, carnauba wax<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><sup>1<\/sup>\u00a0OPADRY contains hypromellose, macrogol, polysorbate 80, and as dyes titanium dioxide E171 (all strengths), yellow iron oxide E172 (50 and 100 mg), and red iron oxide E172 (200 mg).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>25 mg: White round tablets, 6 mm in diameter, debossed with \u201cTOP\u201d on one side and \u201c25\u201d on the other side.<\/p>\n\n\n\n<p>50 mg: Light yellow round tablets, 7 mm in diameter, debossed \u201cTOP\u201d on one side and \u201c50\u201d on the other side.<\/p>\n\n\n\n<p>100 mg: Yellow round tablets, 9 mm in diameter, debossed with \u201cTOP\u201d on one side and \u201c100\u201d on the other side.<\/p>\n\n\n\n<p>200 mg: Salmon pink round tablets, 10 mm in diameter, debossed \u201cTOP\u201d on one side and \u201c200\u201d on the other side.<\/p>\n\n\n\n<p>Opaque plastic bottle with sealed lid containing 20, 28, 30, 50, 56, 60, 100 or 200 (2 x 100) tablets.&nbsp;Each can contains a desiccant container that should not be swallowed.<\/p>\n\n\n\n<p>Printed packaging of aluminum-aluminum foil in maps.\u00a0Pack sizes of 10, 20, 28, 30, 50, 56, 60, 100 or 200 (2 x 100) tablets.\u00a0Individual (alu\/alu) blister cards are packed in an outer carton.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Janssen-Cilag AB<\/p>\n\n\n\n<p>Box 4042<\/p>\n\n\n\n<p>SE-169 04 Solna<\/p>\n\n\n\n<p>Phone: +46 8 626 50 00<\/p>\n\n\n\n<p>jacse@its.jnj.com<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Janssen Pharmaceutica NV<\/p>\n\n\n\n<p>Turnhoutseweg 30<\/p>\n\n\n\n<p>B-2340 Beerse<\/p>\n\n\n\n<p>Belgium<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Janssen-Cilag SpA<\/p>\n\n\n\n<p>Via C. Janssen<\/p>\n\n\n\n<p>Loc.&nbsp;Borgo S. Michele<\/p>\n\n\n\n<p>04100 Latina (LT)<\/p>\n\n\n\n<p>Italy<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Lusomedicamenta \u2013 Sociedade T\u00e9cnica Farmac\u00eautica SA<\/p>\n\n\n\n<p>Estrada Consiglieri Pedroso n\u00ba 69 B<\/p>\n\n\n\n<p>Queluz de Baixo, 2730-055 Barcarena<\/p>\n\n\n\n<p>Portugal<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Topimax belongs to a group of medicines called anti-epileptic medicines.\u00a0It is used:<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[26051,26055,26054,26043,26046,26045,26052,26041,26053,26044],"class_list":["post-25213","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-topimax","tag-topimax-side-effects","tag-topimax-tablet","tag-topiramate","tag-topiramate-side-effects","tag-topiramate-tablet","tag-what-is-topimax","tag-what-is-topiramate","tag-what-topimax-is-used-for","tag-what-topiramate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25213","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=25213"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25213\/revisions"}],"predecessor-version":[{"id":25255,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25213\/revisions\/25255"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=25213"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=25213"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=25213"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}