{"id":25153,"date":"2022-09-09T12:33:59","date_gmt":"2022-09-09T12:33:59","guid":{"rendered":"https:\/\/zeepedia.com\/?p=25153"},"modified":"2022-09-12T07:29:19","modified_gmt":"2022-09-12T07:29:19","slug":"tobrex-depot","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/tobrex-depot\/","title":{"rendered":"Tobrex Depot &#8211; Tobramycin uses, dose and side effects"},"content":{"rendered":"\n<p>3 mg\/ml&nbsp;eye drops, solution<br>tobramycin<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Tobrex Depot is and what it is used for<\/h2>\n\n\n\n<p>Tobrex\u00a0Depot\u00a0contains the active substance tobramycin and is an\u00a0antibiotic.<\/p>\n\n\n\n<p>Tobrex&nbsp;Depot&nbsp;is used to treat superficial bacterial infections of the eye in adults and children over 1 year of age.<\/p>\n\n\n\n<p>Tobramycin contained in Tobrex\u00a0Depot\u00a0may also be approved to treat other conditions not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Tobrex Depot<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Tobrex Depot<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to tobramycin or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Tobrex\u00a0Depot.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you experience allergic reactions such as itchy eyelids, or swollen or red eyes while using Tobrex\u00a0Depot, stop using the eye drops and consult your doctor.\u00a0This allergic sensitivity can occur with other\u00a0aminoglycoside\u00a0antibiotics\u00a0that\u00a0are used topically or taken by mouth.<\/li><li>If you are using another antibiotic treatment at the same time as Tobrex\u00a0Depot, you should ask your doctor for advice.<\/li><li>If you have or have ever had a disease that affects the muscles such as\u00a0myasthenia gravis\u00a0(a disease that causes muscle weakness) or\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/parkinsons-disease\/\">Parkinson&#8217;s disease<\/a>, consult your doctor.\u00a0Antibiotics\u00a0of this type can worsen muscle weakness.<\/li><li>If your symptoms get worse or come back suddenly, consult your doctor.\u00a0If you use Tobrex\u00a0Depot\u00a0for a long time, you may become more susceptible to\u00a0eye infections.<\/li><li>If you wear contact lenses: You should not use contact lenses (hard or soft) during the treatment of an\u00a0eye <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/infection-and-inflammation\/\">infection<\/a>.<\/li><\/ul>\n\n\n\n<p><strong>Children<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Children under 1 year should not use Tobrex\u00a0Depot.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Tobrex Depot<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are using, have recently used, or might be using other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.\u00a0Tobrex\u00a0Depot\u00a0can be used during pregnancy and breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>If you experience temporary blurred vision or other visual disturbances after using Tobrex\u00a0Depot, you should not drive or operate machinery until your vision has cleared.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with a doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Tobrex Depot contains benzododecinium bromide<\/h2>\n\n\n\n<p>If you wear contact lenses:<\/p>\n\n\n\n<p>Take out your contact lenses (hard or soft) before using Tobrex&nbsp;Depot&nbsp;and wait at least 15 minutes before putting them back in.<\/p>\n\n\n\n<p>Tobrex\u00a0Depot\u00a0contains a\u00a0preservative\u00a0(benzododecinium bromide) which can irritate the eyes and has been found to discolor soft contact lenses.\u00a0Avoid contact with soft contact lenses.<\/p>\n\n\n\n<p>However, you should not use contact lenses (hard or soft) during the treatment of an eye infection.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Tobrex Depot<\/h2>\n\n\n\n<p>Always use this medicine as directed by your doctor or pharmacist.<\/p>\n\n\n\n<p>Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>The recommended&nbsp;dose&nbsp;is<\/strong><\/p>\n\n\n\n<p>Adults including the elderly<\/p>\n\n\n\n<p>The usual\u00a0dosage\u00a0is 1 drop in the infected eye(s) 2 times daily \u2013 morning and evening.\u00a0Do not use Tobrex\u00a0Depot\u00a0in both eyes unless your doctor has prescribed it.<\/p>\n\n\n\n<p>Use Tobrex\u00a0Depot\u00a0only as\u00a0eye drops.<\/p>\n\n\n\n<p><strong>How to use Tobrex&nbsp;Depot&nbsp;correctly:<\/strong><\/p>\n\n\n\n<p>Remove the loose collar from the cap when opening the bottle for the first time.&nbsp;Keep the bottle tightly closed when not in use.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20040607011577#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/3086fa9c-59ee-4c9a-b729-a5541e315f73\" alt=\"Administration\" title=\"Administration\"\/><\/a><\/figure>\n\n\n\n<ol class=\"wp-block-list\"><li>Take out the bottle of Tobrex\u00a0Depot.<\/li><li>Wash your hands and sit in front of a mirror.<\/li><li>Twist off the bottle cap.\u00a0<\/li><li>Hold the bottle with the tip down between your thumb and middle finger (picture 1).<\/li><li>Tilt your head back.\u00a0Pull down the lower eyelid with a clean finger until a &#8220;pocket&#8221; is formed between the lower eyelid and the eye.\u00a0This is where the drop should be placed.<\/li><li>Bring the dropper tip of the bottle to the eye.\u00a0Use a mirror if it helps.<\/li><li>Do not touch the eye or eyelid, surrounding areas, or other surfaces with the dropper tip.\u00a0It can contaminate the eye drops in the bottle.<\/li><li>Do not squeeze the bottle: it is designed so that light pressure on the bottom is sufficient (picture 2).<\/li><li>Gently press the bottom of the bottle to release one drop of Tobrex\u00a0Depot\u00a0at a time (picture 3).<\/li><li>After using Tobrex\u00a0Depot, close the eye and gently press with a finger in the corner of the eye near the nose for 2 minutes (picture 4).<\/li><li>If you are using Tobrex\u00a0Depot\u00a0in both eyes, repeat steps 5-9 for the other eye.<\/li><li>Screw the bottle cap tightly immediately after use.<\/li><li>Use only one bottle at a time.<\/li><\/ol>\n\n\n\n<p>If a drop misses the eye, try again.<\/p>\n\n\n\n<p>If you use other eye medicines in the form of drops or ointments, you must wait at least 5 minutes between each medicine.&nbsp;Eye ointments should be used last.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Tobrex&nbsp;Depot&nbsp;can be used for children 1 year and older.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have used too much Tobrex Depot<\/h2>\n\n\n\n<p>Rinse the eye with lukewarm water.\u00a0Do not take any more drops until it is time for your next\u00a0dose.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if, for example,&nbsp;a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Tobrex Depot<\/h2>\n\n\n\n<p>If you forget to take a\u00a0dose, take it as soon as you remember.\u00a0If it is almost time for your next\u00a0dose, skip the missed\u00a0dose.<\/p>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Tobrex Depot<\/h2>\n\n\n\n<p>Do not stop using this medicine prematurely, even if your symptoms have disappeared.&nbsp;If you stop using this medicine too soon, the symptoms may come back.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><em>Common (affects&nbsp;<\/em><em>up to&nbsp;<\/em><em>1&nbsp;<\/em><em>in&nbsp;<\/em><em>10 users):<\/em><\/p>\n\n\n\n<p>Effects in the eyes: eye discomfort, itchy eyes, red eyes, increased tear production.<\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1&nbsp;<\/em><em>in 100&nbsp;<\/em><em>users):<\/em><\/p>\n\n\n\n<p>Effects on the eyes:\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/infection-and-inflammation\/\">inflammation<\/a>\u00a0of the surface of the eye, damage to the cornea, visual impairment, blurred vision, red eyelids, swollen eyes and eyelids, eye pain, dry eyes, watery eyes, and eye allergy.<\/p>\n\n\n\n<p>General side effects:\u00a0allergy\u00a0(hypersensitivity), <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/headache\/\">headache<\/a>, hives, skin inflammation, reduced growth or fewer number of eyelash hairs, loss of skin pigment,\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/dry-skin-and-itching\/\">itching<\/a>,\u00a0and dry skin.<\/p>\n\n\n\n<p><em>Frequency not known (cannot be estimated from available data):<\/em><\/p>\n\n\n\n<p>Effects in the eyes: eye irritation, itchy eyelids.<\/p>\n\n\n\n<p>General side effects: skin rash<strong>.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How Tobrex Depot should be stored<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date stated on the packaging after &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Discard the bottle 4 weeks after opening.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is tobramycin.\u00a0One ml of solution contains 3 mg tobramycin.<\/li><li>Other ingredients are xanthan gum, benzododecinium bromide, mannitol, trometamol, boric acid, polysorbate 80, sulfuric acid, and\/or sodium hydroxide, and purified water.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Tobrex&nbsp;Depot&nbsp;is a clear and colorless solution supplied in a 5 ml plastic bottle (DROPTAINER) with a screw cap.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder:<\/h2>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Alcon-Couvreur NV<\/p>\n\n\n\n<p>Rijksweg 14<\/p>\n\n\n\n<p>2870 Puurs<\/p>\n\n\n\n<p>Belgium<\/p>\n\n\n\n<p>Siegfried El Masnou, SA<\/p>\n\n\n\n<p>Camille Fabra 58<\/p>\n\n\n\n<p>El Masnou 08320<\/p>\n\n\n\n<p>Barcelona<\/p>\n\n\n\n<p>Spain<\/p>\n\n\n\n<p>Novartis Pharma GmbH<\/p>\n\n\n\n<p>Roonstrasse 25<\/p>\n\n\n\n<p>90429 Nuremberg<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>Novartis Farmac\u00e9utica SA<\/p>\n\n\n\n<p>Gran Via de Les Corts Catalanes, 764<\/p>\n\n\n\n<p>08013 Barcelona<\/p>\n\n\n\n<p>Spain<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tobrex\u00a0Depot\u00a0contains the active substance tobramycin and is an\u00a0antibiotic\u00a0.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[18611,26030,18607,18610,26026,26029,18608,26027,18609,26028],"class_list":["post-25153","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-benefits-of-tobramycin","tag-benefits-of-tobrex-depot","tag-tobramycin","tag-tobramycin-side-effects","tag-tobrex-depot","tag-tobrex-depot-side-effects","tag-what-is-tobramycin","tag-what-is-tobrex-depot","tag-what-tobramycin-is-used-for","tag-what-tobrex-depot-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25153","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=25153"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25153\/revisions"}],"predecessor-version":[{"id":25194,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25153\/revisions\/25194"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=25153"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=25153"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=25153"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}