{"id":25066,"date":"2022-09-06T07:36:17","date_gmt":"2022-09-06T07:36:17","guid":{"rendered":"https:\/\/zeepedia.com\/?p=25066"},"modified":"2022-09-07T07:40:35","modified_gmt":"2022-09-07T07:40:35","slug":"timosan","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/timosan\/","title":{"rendered":"Timosan &#8211; Timolol uses, dose and side effects"},"content":{"rendered":"\n<p>1 mg\/ml&nbsp;depot eye drops<br><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/azarga\/\">timolol<\/a><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Timosan is and what it is used for<\/h2>\n\n\n\n<p>Timosan contains\u00a0timolol, which is a\u00a0beta-blocker\u00a0that lowers eye pressure by reducing fluid formation in the anterior chamber.<\/p>\n\n\n\n<p>Thymosin\u00a0is used to lower the eye pressure in\u00a0chronic\u00a0glaucoma\u00a0(open-angle\u00a0glaucoma ) and cases of too high pressure in the eye.<\/p>\n\n\n\n<p>The timolol\u00a0contained in Timosan may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Timosan<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Timosan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to\u00a0timolol,\u00a0beta-blockers,\u00a0or any other ingredient in this medicine (listed in section 6)<\/li><li>if you currently have or have previously had respiratory problems, e.g.\u00a0asthma, severe\u00a0chronic\u00a0obstructive\u00a0bronchitis\u00a0(a serious lung disease that can cause wheezing, difficulty breathing, and\/or prolonged coughing)<\/li><li>if you have a low\u00a0heart rate,\u00a0heart failure,\u00a0or heart rhythm disturbances (irregular heart rhythm).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor before using Timosan if you currently have or have had it in the past<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>coronary heart disease (with symptoms such as chest pain, chest tightness, shortness of breath or shortness of breath),\u00a0heart failure, low\u00a0blood pressure<\/li><li>disturbances in the heart rhythm, e.g.\u00a0slow heartbeat<\/li><li>breathing problems,\u00a0asthma,\u00a0or\u00a0chronic obstructive pulmonary disease\u00a0(COPD)<\/li><li>a disease that causes impaired blood circulation (e.g.\u00a0Raynaud&#8217;s disease\u00a0or Raynaud&#8217;s syndrome)<\/li><li>diabetes, as\u00a0timolol\u00a0may mask signs and symptoms of low blood sugar<\/li><li>the overactive\u00a0thyroid gland, as\u00a0timolol\u00a0can mask disease signs and symptoms<\/li><li>atopy (hereditary tendency to develop\u00a0allergy\u00a0) or severe anaphylactic (allergic) reaction, as\u00a0timolol\u00a0may affect the effectiveness of\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/adrenaline-bradex\/\">adrenaline<\/a>\u00a0(used for treatment in\u00a0anaphylactic reaction\u00a0)<\/li><li>the disease of the cornea (the front layer of the eyeball), as\u00a0beta blockers\u00a0can cause dry eyes<\/li><\/ul>\n\n\n\n<p>If you are going to undergo an operation, you must inform the doctor that you are using Timosan, as\u00a0timolol\u00a0can affect the effectiveness of certain drugs used in anesthesia.<\/p>\n\n\n\n<p><strong>Children<\/strong><\/p>\n\n\n\n<p>Timosan is not recommended for children, as clinical experience is lacking.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Timosan<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might be taking other medicines. Timosan can affect or be affected by other medicines that you are using, including other\u00a0eye drops\u00a0for\u00a0glaucoma.<\/p>\n\n\n\n<p>Tell your doctor if you are using or intend to use:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>drugs that lower\u00a0blood pressure, etc<\/li><li>heart medications<\/li><li>quinidine\u00a0(used in heart disease and to treat certain types of\u00a0malaria\u00a0)<\/li><li>drugs against\u00a0diabetes.<\/li><li>medicines for depression that contain\u00a0fluoxetine\u00a0or\u00a0paroxetine<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, consult your doctor before using this medicine.<\/p>\n\n\n\n<p>Do not use Timosan if you are pregnant, unless your doctor considers it necessary.&nbsp;There is a risk that the fetus will be affected.<\/p>\n\n\n\n<p>Do not use Timosan if you are breastfeeding.\u00a0Thymosin can be transferred into breast milk.<\/p>\n\n\n\n<p>If you are breastfeeding, consult your doctor before taking any medicine.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Timosan can cause short-term transient blurred vision in connection with instillation.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Thymosan contains 0.05 mg benzalkonium chloride per ml<\/h2>\n\n\n\n<p>Timosan\u00a0eye drops\u00a0in a bottle contain the preservative benzalkonium chloride.\u00a0Benzalkonium chloride can be absorbed by soft contact lenses and can discolor the contact lenses.\u00a0Remove contact lenses before using the medicine and wait at least 30 minutes before putting them back in.\u00a0Benzalkonium chloride can be irritating to the eyes, especially if you have dry eyes or problems with the cornea (the clear membrane at the front of the eye).\u00a0If you feel irritation, tingling, or pain in the eye after using the medicine, consult a doctor.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Timosan<\/h2>\n\n\n\n<p>Always use this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The dose&nbsp;is determined by the doctor who adjusts it individually for you.&nbsp;The recommended&nbsp;dose&nbsp;is one drop a day in the eye(s).&nbsp;Means given at the same time as Timosan in the eye should be given at least 10 minutes apart.<\/p>\n\n\n\n<p>After you have applied Timosan, press a finger into the corner of the eye closest to the nose (fig. 4) and hold the finger there for 2 minutes.&nbsp;In this way, you prevent&nbsp;timolol from&nbsp;reaching other parts of the body.<\/p>\n\n\n\n<p><strong>Before use:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>wash your hands<\/li><li>choose the position that feels most natural to you (e.g. you can sit down, lie on your back or stand in front of the mirror)<\/li><\/ul>\n\n\n\n<p><strong>Application:<\/strong><\/p>\n\n\n\n<p>1. Open the bottle.&nbsp;Avoid touching anything with the tip of the bottle to avoid contaminating the contents.<\/p>\n\n\n\n<p>2. Tilt your head back and hold the bottle above your eye.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20000505000035#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Santen\/Media\/Artelac1.jpg\" alt=\"Timosan picture 1\" title=\"Timosan picture 1\"\/><\/a><\/figure>\n\n\n\n<p>3. Pull the lower eyelid down, direct the gaze upwards and squeeze a drop into the eye.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20000505000035#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Santen\/Media\/Artelac2.jpg\" alt=\"Timosan picture 2\" title=\"Timosan picture 2\"\/><\/a><\/figure>\n\n\n\n<p>4. Close the eye and press the inner corner of the eye with your finger for 2 minutes.&nbsp;In this way, you avoid the eye medication running down the tear duct.&nbsp;Close the bottle.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20000505000035#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/Santen\/Media\/Fotil3.jpg\" alt=\"Timosan picture 3\" title=\"Timosan picture 3\"\/><\/a><\/figure>\n\n\n\n<p>The eye drop bottle is personal.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have used too much Timosan<\/h2>\n\n\n\n<p>Too large a\u00a0dose\u00a0of Timosan can be flushed out of the eye with lukewarm tap water.\u00a0If you have ingested too much medicine or if, for example,\u00a0a child has accidentally ingested the medicine, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Timosan<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Timosan<\/h2>\n\n\n\n<p>Do not stop treatment with Timosan without first talking to your doctor.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Stop taking Timosan and contact your doctor immediately if swelling occurs in e.g.\u00a0face, tongue, and\/or throat or if you experience\u00a0hives\u00a0or shortness of breath, or difficulty swallowing.<\/p>\n\n\n\n<p>You can usually continue to use the drops unless the\u00a0side effects\u00a0are severe.\u00a0Talk to your doctor or pharmacist if you are worried.\u00a0Do not stop treatment with Timosan without first talking to your doctor.<\/p>\n\n\n\n<p>Common (may affect up to 1 in 10 users): burning sensation in the eyes and redness (eye irritation) and visual disturbances such as blurred vision.<\/p>\n\n\n\n<p>Uncommon (may affect up to 1 in 100 users):&nbsp;inflammation&nbsp;of the eye&#8217;s&nbsp;conjunctiva&nbsp;or&nbsp;cornea&nbsp;(the front layer of the eyeball), dry eyes and a feeling of having &#8220;garbage&#8221; in the eye, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/headache\/\">headache<\/a>, dizziness, shortness of breath.<\/p>\n\n\n\n<p>Rare (may affect up to 1 in 1,000 users): e.g.&nbsp;decreased sensitivity of the cornea.<\/p>\n\n\n\n<p>As with other eye medicines,\u00a0timolol\u00a0is absorbed into the blood.\u00a0This can cause\u00a0side effects\u00a0similar to those seen with\u00a0beta-blockers\u00a0taken by mouth (orally) or given by\u00a0injection.\u00a0The occurrence of\u00a0side effects\u00a0after the medicine has been dropped into the eye is lower than when the medicine is taken by mouth or by\u00a0injection.\u00a0Among the\u00a0side effects\u00a0listed are the following reactions seen within the group of beta-blockers\u00a0for use in the eyes:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic reactions affecting the whole body include\u00a0angioedema\u00a0(swelling under the skin, which can appear on the face, arms and legs, and can make it difficult to swallow and breathe), hives, local or general rash,\u00a0itching, sudden severe life-threatening\u00a0allergic reaction.<\/li><li>Low blood sugar level.<\/li><li>Difficulty sleeping (insomnia), depression, nightmares, memory loss, confusion, hallucination.<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/fainting\/\">Fainting<\/a>,\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/stroke\/\">stroke<\/a>, reduced blood supply to the brain, increased symptoms and signs of\u00a0myasthenia gravis\u00a0(muscle disease), abnormal sensations such as tingling and pins and needles.<\/li><li>Eye irritation (e.g. stinging,\u00a0itching, watery eyes), eyelid inflammation, detachment of the blood vessel-containing membrane under the retina after filtration surgery, which can cause visual disturbances, corneal\u00a0erosion\u00a0(damage to the front layer of the eyeball), drooping eyelids (which causes the eye remains half closed), double vision, reduced tear secretion, refractive changes (visual disturbances).<\/li><li>Low\u00a0heart rate, chest pain, palpitations,\u00a0edema\u00a0(fluid accumulation), altered\u00a0pulse\u00a0or heart rhythm,\u00a0chronic\u00a0heart failure\u00a0(heart disease with shortness of breath, swollen feet and legs, due to fluid accumulation), a type of heart rhythm disorder, heart attack,\u00a0heart failure.<\/li><li>Low\u00a0blood pressure, Raynaud&#8217;s phenomenon, cold hands, and feet.<\/li><li>Narrowing of the airways in the lungs (especially in patients with existing disease), cough.<\/li><li>Taste disturbances, nausea, digestive problems, diarrhea,\u00a0dry mouth, abdominal pain, and vomiting.<\/li><li>Hair loss, white\/silver colored (psoriasis-like) skin rash or worsening\u00a0psoriasis, and other forms of skin rash.<\/li><li>Muscle pain that is not exercise-related.<\/li><li>Impaired sexual function, decreased sex drive, Peyronie&#8217;s disease (which causes scar tissue and calluses in the penis).<\/li><li>Muscle weakness, muscle fatigue.<\/li><li>Tinnitus.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How Timosan should be stored<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Store at a maximum of 25 \u00b0C.\u00a0Do not freeze.<\/li><li>Store in the outer packaging.\u00a0Light sensitive.<\/li><li>The opened bottle is stable for 4 weeks.<\/li><li>The packaging should be stored upside down for better dripping.<\/li><li>Use before the expiry date stated on the packaging.\u00a0The expiration date is the last day of the specified month.<\/li><li>Do not use this medicine if you see signs that it has changed.<\/li><li>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<p><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is timolol maleate corresponding to 1 mg\/ml\u00a0timolol\u00a0.<\/li><li>Other ingredients are benzalkonium chloride (\u00a0preservative\u00a0) 0.05 mg\/ml, sorbitol, polyvinyl alcohol, carbomer, sodium acetate trihydrate, lysine monohydrate, and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>The dropper bottle is made of polyethylene and is equipped with a dropper and screw cap.<\/p>\n\n\n\n<p>Pack sizes: 1 x 5 ml and 3 x 5 ml.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Santen Oy<\/p>\n\n\n\n<p>Niittyhaankatu 20<\/p>\n\n\n\n<p>FI-33720 Tampere<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Santen Oy<\/p>\n\n\n\n<p>Kelloportinkatu 1<\/p>\n\n\n\n<p>FI-33100 Tampere<\/p>\n\n\n\n<p>Finland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Timosan contains\u00a0timolol\u00a0, which is a\u00a0beta-blocker\u00a0that lowers eye pressure by reducing fluid formation in the anterior chamber.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[5029,5248,5031,25938,25939,25942,5030,25940,8380,25941],"class_list":["post-25066","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-timolol","tag-timolol-eye-drops","tag-timolol-side-effects","tag-timosan","tag-timosan-eye-drops","tag-timosan-side-effects","tag-what-is-timolol","tag-what-is-timosan","tag-what-timolol-is-used-for","tag-what-timosan-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25066","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=25066"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25066\/revisions"}],"predecessor-version":[{"id":25096,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/25066\/revisions\/25096"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=25066"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=25066"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=25066"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}