{"id":24664,"date":"2022-08-29T11:51:13","date_gmt":"2022-08-29T11:51:13","guid":{"rendered":"https:\/\/zeepedia.com\/?p=24664"},"modified":"2022-08-30T07:39:43","modified_gmt":"2022-08-30T07:39:43","slug":"tenofovir-disoproxil-glenmark","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/tenofovir-disoproxil-glenmark\/","title":{"rendered":"Tenofovir Disoproxil Glenmark &#8211; Tenofovir disoproxil uses, dose and side effects"},"content":{"rendered":"\n<p>245 mg&nbsp;film-coated tablets<br>tenofovir disoproxil<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Tenofovir disoproxil Glenmark is and what it is used for<\/h2>\n\n\n\n<p>Tenofovir disoproxil Glenmark contains the active substance\u00a0<em>tenofovir disoproxil<\/em>.\u00a0This active substance is an\u00a0antiretroviral\u00a0or antiviral medicine used to treat\u00a0HIV\u00a0or HBV\u00a0infection\u00a0or both.\u00a0Tenofovir is a\u00a0reverse transcriptase inhibitor of the nucleotide type, generally called an NRTI, and works by affecting the normal function of\u00a0enzymes\u00a0(in the case of\u00a0HIV\u00a0reverse transcriptase; in the case of HBV\u00a0DNA polymerase\u00a0) that the\u00a0virus\u00a0needs for its reproduction (propagation).\u00a0In\u00a0HIV should Tenofovir disoproxil Glenmark always be taken in combination with other medicines against\u00a0HIV?<\/p>\n\n\n\n<p><strong>Tenofovir disoproxil Glenmark is a treatment for\u00a0HIV<\/strong>\u00a0(human immunodeficiency virus\u00a0<strong>)\u00a0<\/strong>infection.\u00a0The tablets are suitable for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>adults<\/strong><\/li><li><strong>young people aged 12 to younger than 18 years who have already been treated<\/strong>\u00a0with other\u00a0HIV\u00a0drugs that no longer have a satisfactory effect due to the development of resistance or have caused\u00a0side effects.<\/li><\/ul>\n\n\n\n<p><strong>Tenofovir disoproxil Glenmark is also used as a treatment for\u00a0chronic\u00a0hepatitis\u00a0B, infection\u00a0with HBV<\/strong>\u00a0(\u00a0hepatitis\u00a0B\u00a0virus\u00a0).\u00a0The tablets are suitable for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>adults<\/strong><\/li><li><strong>young people aged 12 to younger than 18 years.<\/strong><\/li><\/ul>\n\n\n\n<p>You do not have to have&nbsp;HIV&nbsp;to be treated with Tenofovir disoproxil Glenmark for HBV.<\/p>\n\n\n\n<p>This medicine does not\u00a0cure\u00a0HIV\u00a0infection.\u00a0While taking Tenofovir\u00a0disoproxil Glenmark you may still develop\u00a0an infection\u00a0or other diseases associated with\u00a0HIV\u00a0infection.\u00a0You can also pass\u00a0HIV\u00a0or HBV on to others, so you must take precautions to avoid infecting other people.<\/p>\n\n\n\n<p>Tenofovir disoproxil contained in Tenofovir disoproxil Glenmark may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Tenofovir disoproxil Glenmark<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Tenofovir disoproxil Glenmark<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>if you are allergic<\/strong>\u00a0to tenofovir, tenofovir disoproxil, or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<p>If this applies to you,\u00a0<strong>tell your doctor immediately and stop taking Tenofovir disoproxil Glenmark<\/strong><strong>.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Tenofovir disoproxil Glenmark.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Be careful not to infect other people.\u00a0<\/strong>You can still transmit\u00a0HIV\u00a0when taking this medicine, although the risk is reduced with effective\u00a0antiviral\u00a0treatment.\u00a0Discuss with your doctor the necessary measures to avoid infecting others.\u00a0Tenofovir disoproxil Glenmark does not reduce the risk of transmitting HBV to others through sexual contact or blood infection.\u00a0You still need to take precautions to avoid this<strong>.<\/strong><\/li><li><strong>Talk to your doctor or pharmacist if you have had kidney disease in the past or if tests have shown that you have problems with your kidneys.\u00a0<\/strong>Tenofovir disoproxil Glenmark should not be given to adolescents with kidney problems.\u00a0Before starting the treatment, your doctor may\u00a0order\u00a0some blood tests to assess that your kidneys are working normally.\u00a0Tenofovir disoproxil Glenmark can affect your kidneys during treatment.\u00a0Your doctor may\u00a0order\u00a0blood tests during treatment to check how your kidneys are working.\u00a0If you are an adult, your doctor may advise you to take the tablets less often.\u00a0Do not reduce the prescribed\u00a0dose by\u00a0one unless your doctor has told you to do so.<br>Tenofovir disoproxil Glenmark is not usually taken together with other medicines that can damage the kidneys (see\u00a0<em>Other medicines and\u00a0<\/em><em>Tenofovir disoproxil Glenmark<\/em>\u00a0).\u00a0If this cannot be avoided, your doctor will check your kidney function once a week.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Skeletal problems.\u00a0<\/strong>Some adult patients with\u00a0HIV\u00a0receiving\u00a0combination\u00a0antiretroviral\u00a0therapy may develop a bone disease called\u00a0osteonecrosis\u00a0(bone tissue dies due to loss of blood supply to the bone).\u00a0Some of the many risk factors for developing the disease are long-term\u00a0combination\u00a0antiretroviral\u00a0therapy, use of\u00a0corticosteroids, alcohol consumption, severe impairment of the immune system, and higher body mass index.\u00a0Signs of\u00a0osteonecrosis\u00a0are joint stiffness and <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a> (especially in the hip, knee, and shoulders) and difficulty moving.\u00a0Tell your doctor if you experience any of these symptoms.<br>Bone problems (manifesting as persistent or worsening bone pain and sometimes leading to\u00a0fractures\u00a0) may also occur due to damage to renal tubule cells (see section 4, Possible\u00a0side effects\u00a0).\u00a0Tell your doctor if you have bone pain or\u00a0a fracture.<br>Tenofovir disoproxil can also cause loss of bone mass.\u00a0The most pronounced loss of bone mass was seen in\u00a0clinical trials\u00a0when patients were treated with tenofovir disoproxil in combination with a boosted\u00a0protease inhibitor.<br>Overall, the effects of tenofovir disoproxil on long-term bone health and future fracture risk in adults and children are uncertain.\u00a0Tell your doctor if you know you have osteoporosis.\u00a0Patients with osteoporosis are at higher risk of\u00a0fracture.<\/li><li>Inform your doctor if you already have or have had liver disease, including\u00a0hepatitis<strong>.\u00a0<\/strong>Patients with liver disease, including\u00a0chronic\u00a0hepatitis\u00a0B or C, who are treated with antiretroviral agents are at increased risk of severe and potentially fatal liver complications.\u00a0If you have\u00a0hepatitis\u00a0B, your doctor will carefully choose the best treatment for you.\u00a0If you have or have had liver disease or\u00a0chronic\u00a0hepatitis\u00a0B, your doctor may take blood tests to check liver function.\u00a0<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Be observant about\u00a0infection<\/strong>.\u00a0If you have\u00a0advanced stage\u00a0HIV\u00a0infection (\u00a0AIDS\u00a0) and have an\u00a0infection, you may develop symptoms of\u00a0infection\u00a0and\u00a0inflammation\u00a0or worsening of symptoms of an existing\u00a0infection when\u00a0treatment\u00a0with Tenofovir disoproxil Glenmark is started.\u00a0These symptoms may indicate that your body&#8217;s improved immune system is fighting\u00a0infection.\u00a0Watch for signs of\u00a0inflammation\u00a0or\u00a0infection\u00a0during the first period after you start taking Tenofovir disoproxil Glenmark.\u00a0If you discover signs of inflammation\u00a0or\u00a0infection,\u00a0you should immediately inform your doctor.<br>In addition to opportunistic\u00a0infections, autoimmune disorders (conditions where the immune system attacks healthy body tissue) can also occur after you start taking medicines to treat\u00a0your\u00a0HIV\u00a0infection.\u00a0Autoimmune disorders may occur several months after starting treatment.\u00a0If you notice any symptoms of\u00a0infection\u00a0or other symptoms such as muscle weakness, a weakness that starts in the hands or feet and moves to the trunk, palpitations, tremors, or hyperactivity, inform your doctor immediately to get the necessary treatment.<\/li><li><strong>Talk to your doctor or pharmacist if you are over 65.\u00a0<\/strong>Tenofovir disoproxil Glenmark has not been studied in patients over 65 years of age.\u00a0If you are older than that and have been prescribed Tenofovir disoproxil Glenmark, your doctor will monitor you closely.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Tenofovir disoproxil Glenmark is&nbsp;<strong>suitable<\/strong>&nbsp;for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>HIV\u00a0-1 -infected young people aged 12 to less than 18 years who weigh at least 35 kg and who have already been treated<\/strong>\u00a0with other\u00a0HIV\u00a0drugs that no longer have the full effect due to the development of resistance or have caused\u00a0side effects.<\/li><li><strong>HBV-infected adolescents aged 12 to younger than 18 years who weigh at least 35 kg.<\/strong><\/li><\/ul>\n\n\n\n<p>Tenofovir disoproxil Glenmark is&nbsp;<strong>not<\/strong>&nbsp;suitable for the following groups:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Not for\u00a0HIV\u00a0-1-infected children<\/strong>\u00a0under 12 years of age\u00a0<\/li><li><strong>Not for HBV-infected children<\/strong>\u00a0under 12 years of age<strong>.<\/strong><\/li><\/ul>\n\n\n\n<p>For\u00a0dosage, see section 3,\u00a0How to take Tenofovir disoproxil Glenmark.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Tenofovir disoproxil Glenmark<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Do not stop taking any anti-HIV<\/strong>\u00a0medicine prescribed by your doctor when you start taking Tenofovir disoproxil Glenmark if you have both HBV and\u00a0HIV.<\/li><li>Do not take Tenofovir disoproxil Glenmark\u00a0if you are already taking other medicines containing tenofovir disoproxil or tenofovir alafenamide.\u00a0Do not take Tenofovir disoproxil Glenmark with medicines containing adefovir dipivoxil (a medicine used to treat\u00a0chronic\u00a0hepatitis\u00a0B).<\/li><li>You must tell your doctor if you are taking other medicines that can damage your kidneys. Such drugs are:<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>aminoglycosides, pentamidine or vancomycin (against a bacterial\u00a0infection\u00a0),<\/li><li>amphotericin B (for fungal infection),<\/li><li>foscarnet, ganciclovir, or cidofovir (for viral infection),<\/li><li>interleukin-2\u00a0(for the treatment of <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/getting-a-cancer-message\/\">cancer<\/a>),<\/li><li>adefovir dipivoxil (for HBV),<\/li><li>tacrolimus (for\u00a0suppressing\u00a0the immune system),<\/li><li>non-steroidal anti-inflammatory drugs (\u00a0NSAIDs, to relieve bone or muscle pain).<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Other medicines containing didanosine (for\u00a0HIV\u00a0infection\u00a0): If you take Tenofovir\u00a0disoproxil<\/strong>\u00a0Glenmark together with other antiviral medicines containing didanosine, the blood levels of didanosine may increase and the CD4 cell count may decrease.\u00a0Rare cases of pancreatitis and lactic acidosis (excess\u00a0lactic acid\u00a0in the blood), in some cases with a fatal outcome, have been reported during concomitant treatment with medicines containing tenofovir disoproxil and didanosine.\u00a0Your doctor will carefully consider whether you can be treated with a combination of tenofovir and didanosine.<\/li><li><strong>It is also important that you tell your doctor<\/strong>\u00a0if you are taking ledipasvir\/sofosbuvir, sofosbuvir\/velpatasvir or sofosbuvir\/velpatasvir\/voxilaprevir to treat\u00a0hepatitis\u00a0C\u00a0infection\u00a0.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Tenofovir disoproxil Glenmark with food and drink<\/h2>\n\n\n\n<p><strong>Take Tenofovir disoproxil Glenmark with food<\/strong>&nbsp;(eg a meal or a snack).<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If you are pregnant, you must not take\u00a0<\/strong>\u00a0<strong>Tenofovir disoproxil Glenmark unless<\/strong>\u00a0you have specifically discussed this with your doctor.\u00a0Although there are limited clinical data on the use of tenofovir disoproxil during pregnancy, it is usually not used unless necessary.<\/li><li>If you become\u00a0or are planning to become\u00a0pregnant, you must contact your doctor to discuss the potential benefits and risks of your antiretroviral treatment for you and your baby.<\/li><li>If you have taken Tenofovir disoproxil Glenmark\u00a0during your pregnancy, the doctor may request that the baby regularly give blood samples and undergo other examinations to check the baby&#8217;s development.\u00a0For children whose\u00a0mothers\u00a0took drugs such as NRTIs during pregnancy, the benefit of protection against\u00a0HIV\u00a0is greater than the risk of\u00a0side effects.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are a mother and you have HBV and your baby has received treatment to prevent the transmission of\u00a0hepatitis\u00a0B at birth, you may be able to breastfeed your baby, but talk to your doctor first for more information<\/li><li>If you are an\u00a0HIV\u00a0-infected mother, you should not breastfeed your baby to avoid transmission of the\u00a0virus\u00a0to the baby through breast milk.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Tenofovir disoproxil Glenmark can cause dizziness.&nbsp;<strong>Do not drive or cycle or<\/strong>&nbsp;use tools or machines if you feel dizzy while taking Tenofovir disoproxil Glenmark.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Tenofovir disoproxil Glenmark&nbsp;<\/strong><strong>contains&nbsp;lactose<\/strong><\/p>\n\n\n\n<p><strong>Talk to your doctor before taking\u00a0<\/strong>\u00a0<strong>Tenofovir disoproxil Glenmark<\/strong><strong>.\u00a0<\/strong>If you have an intolerance to certain sugars, you should consult your doctor before taking this medicine.<\/p>\n\n\n\n<p><strong>Tenofovir disoproxil Glenmark&nbsp;<\/strong><strong>contains&nbsp;phosphate<\/strong><\/p>\n\n\n\n<p>Talk to your doctor if you cannot take\u00a0phosphate\u00a0or if you have a phosphate-reduced diet.\u00a0Each tablet contains 46 mg\u00a0of phosphate.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Tenofovir disoproxil Glenmark<\/h2>\n\n\n\n<p><strong>Always take this medicine as directed by your doctor or pharmacist<\/strong>.\u00a0Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Adults:<\/strong>&nbsp;1 tablet a day with food (e.g. a meal or a snack).<\/li><li><strong>Adolescents aged 12 to less than 18 years weighing at least 35 kg:<\/strong>&nbsp;1 tablet a day with food (eg a meal or a snack).<\/li><\/ul>\n\n\n\n<p>If you have particular difficulty swallowing, you can crush the tablet with the tip of a spoon.\u00a0Then mix the powder with about 100 ml (half a glass) of water, orange juice, or grape juice and drink immediately.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Always take the\u00a0dose\u00a0prescribed by the doctor<\/strong>\u00a0to ensure that the medicine is effective and to reduce the development of\u00a0resistance\u00a0to the treatment.\u00a0Do not change the\u00a0dose\u00a0unless your doctor tells you to.<\/li><li><strong>If you are an adult and have kidney problems<\/strong>, your doctor may advise you to take Tenofovir disoproxil Glenmark less often.<\/li><li>If you have HBV, your doctor may offer you an\u00a0HIV\u00a0test to see if you have both HBV and\u00a0HIV.<\/li><\/ul>\n\n\n\n<p>Read the package leaflets of the other antiretroviral medicines for information on how to take these medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Tenofovir disoproxil Glenmark<\/h2>\n\n\n\n<p>If you accidentally take too many Tenofovir disoproxil Glenmark tablets, you may be at risk of possible\u00a0side effects\u00a0from this medicine (see section 4,\u00a0<em>Possible\u00a0side effects\u00a0)<\/em>.\u00a0Contact your doctor or nearest emergency department for advice.\u00a0Save the packaging so you can easily describe what you have taken.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Tenofovir disoproxil Glenmark<\/h2>\n\n\n\n<p>You mustn&#8217;t miss a\u00a0dose\u00a0of Tenofovir disoproxil Glenmark.\u00a0If you miss a\u00a0dose, work out when you should have taken it.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If it is less than 12 hours<\/strong>\u00a0after the time it is usually taken, take it as soon as possible, then take the next\u00a0dose\u00a0at its regular time.<\/li><li><strong>If it has been more than 12 hours<\/strong>\u00a0since you should have taken it, do not take the missed\u00a0dose.\u00a0Wait and take the next\u00a0dose\u00a0at its regular time.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed tablet.<\/li><\/ul>\n\n\n\n<p><strong>If you vomit less than 1 hour after a&nbsp;dose&nbsp;of Tenofovir disoproxil Glenmark,<\/strong>&nbsp;take another tablet.&nbsp;You do not need to take another tablet if you vomit more than 1 hour after taking Tenofovir disoproxil Glenmark.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Tenofovir disoproxil Glenmark<\/h2>\n\n\n\n<p>Do not stop taking this medicine without consulting a doctor.&nbsp;Discontinuing treatment with Tenofovir disoproxil Glenmark may result in a reduced effect of the treatment recommended by your doctor.<\/p>\n\n\n\n<p>If you have\u00a0hepatitis\u00a0B or\u00a0HIV\u00a0infection\u00a0and\u00a0hepatitis\u00a0B\u00a0infection\u00a0at the same time,\u00a0you mustn&#8217;t stop Tenofovir disoproxil Glenmark treatment without first talking to your doctor.\u00a0Some patients&#8217; blood tests or symptoms have shown that their\u00a0hepatitis\u00a0has worsened when treatment with Tenofovir disoproxil Glenmark has been stopped.\u00a0You may need to provide blood samples for several months after the end of treatment.\u00a0In patients with advanced liver disease or\u00a0cirrhosis, discontinuation of treatment is not recommended as this may lead to a worsening of the hepatitis infection in some patients.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Talk to your doctor before you stop taking Tenofovir disoproxil Glenmark for any reason, especially if you experience any\u00a0side effects\u00a0or have another illness.<\/li><li>Tell your doctor immediately about any new and unexpected symptoms that appear after stopping treatment, especially symptoms that you usually associate with your\u00a0hepatitis\u00a0B\u00a0infection.<\/li><li>Contact your doctor before you start taking Tenofovir disoproxil Glenmark again.<\/li><\/ul>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>During\u00a0HIV\u00a0treatment, weight gain and increased levels of\u00a0lipids\u00a0and\u00a0glucose\u00a0in the blood may occur.\u00a0This is partly related to restored health and lifestyle, but in the case of blood lipids, there can sometimes be a connection with the\u00a0HIV\u00a0drugs.\u00a0The doctor will do tests to find such changes.<\/p>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Any serious side effects: inform your doctor immediately<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swelling of the face, lips, tongue, or throat is a\u00a0<strong>rare\u00a0<\/strong>side effect\u00a0(may affect up to 1 in 1,000 people)<\/li><li><strong>Lactic acidosis<\/strong>\u00a0(excess\u00a0lactic acid\u00a0in the blood) is a\u00a0<strong>rare<\/strong>\u00a0(may affect up to 1 in 1,000 users) but serious\u00a0side effect\u00a0that can be fatal.\u00a0The following\u00a0side effects\u00a0can be signs of lactic acidosis:<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>deep, rapid breathing<\/li><li>drowsiness<\/li><li>nausea, vomiting, and abdominal pain<\/li><\/ul>\n\n\n\n<p>If you think you may have&nbsp;<strong>lactic acidosis, contact your doctor immediately.<\/strong><\/p>\n\n\n\n<p><strong>Other possible serious\u00a0side effects\u00a0are<\/strong><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;are&nbsp;<strong>less common<\/strong>&nbsp;(may affect up to 1 in 100 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>pain in the stomach<\/strong>&nbsp;(abdomen) caused by&nbsp;inflammation&nbsp;of the pancreas<\/li><li>damage to the kidney (renal tubule cells)<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;are&nbsp;<strong>rare<\/strong>&nbsp;(may affect up to 1 in 1,000 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>kidney inflammation, that you\u00a0<strong>urinate a lot, and that you feel thirsty<\/strong><\/li><li><strong>changes in urine<\/strong>\u00a0and\u00a0<strong><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/back-hurts\/\">back pain<\/a><\/strong>\u00a0caused by kidney problems, including\u00a0kidney failure<\/li><li>decreased bone hardness (which causes\u00a0<strong>bone pain<\/strong>\u00a0and sometimes leads to\u00a0fractures\u00a0), which can occur due to damage to renal tubule cells<\/li><li><strong>fatty liver<\/strong><\/li><\/ul>\n\n\n\n<p><strong>If you think you may have any of these serious\u00a0side effects, talk to your doctor.<\/strong><\/p>\n\n\n\n<p><strong>The most common&nbsp;side&nbsp;effects<\/strong><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;are&nbsp;<strong>very common<\/strong>&nbsp;(may affect more than 1 in 10 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>diarrhea, vomiting, nausea, dizziness, skin rash, feeling weak<\/li><\/ul>\n\n\n\n<p><em>Samples may also show:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>lowered phosphate level in the blood<\/li><\/ul>\n\n\n\n<p><strong>Other possible\u00a0side effects\u00a0are<\/strong><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;are&nbsp;<strong>common<\/strong>&nbsp;(may affect up to 1 in 10 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache, stomach (abdominal) pain, feeling tired, feeling bloated, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/flatulence\/\">flatulence<\/a><\/li><\/ul>\n\n\n\n<p><em>Samples may also show:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>liver problems<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;are&nbsp;<strong>less common<\/strong>&nbsp;(may affect up to 1 in 100 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>muscle breakdown, muscle pain, or muscle weakness<\/li><\/ul>\n\n\n\n<p><em>Samples may also show:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>lowered potassium levels in the blood<\/li><li>increased creatinine level in the blood<\/li><li>pancreatic disorders<\/li><\/ul>\n\n\n\n<p>The breakdown of muscles decreased bone hardness (which causes bone pain and sometimes leads to\u00a0fractures\u00a0), muscle pain, muscle weakness, and lowered\u00a0potassium\u00a0or phosphate levels in the blood can occur due to damage to kidney tubule cells.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;are&nbsp;<strong>rare<\/strong>&nbsp;(may affect up to 1 in 1,000 users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>pain in the stomach (abdomen) caused by&nbsp;inflammation&nbsp;of the liver<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Tenofovir disoproxil Glenmark<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the label and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store at a maximum of 25&nbsp;<sup>o<\/sup>&nbsp;C.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>The active substance<\/strong>\u00a0is tenofovir disoproxil.\u00a0Each film-coated tablet contains tenofovir disoproxil phosphate equivalent to 245 mg of tenofovir disoproxil.<\/li><li>Other ingredients are microcrystalline cellulose, croscarmellose sodium, stearic acid,\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/lactose-intolerance\/\">lactose<\/a> monohydrate, hypromellose (E464), titanium dioxide (E171), triacetin, and indigo carmine aluminum lacquer (E132).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Tenofovir disoproxil Glenmark 245 mg tablets are blue, oval, biconvex film-coated tablets marked with \u201cT1\u201d on one side.&nbsp;No markings on the other, approximately 16.7 x 9.3mm in size.<\/p>\n\n\n\n<p>Tenofovir disoproxil Glenmark is supplied in white plastic bottles.&nbsp;Each can contains two silica gel desiccant bags.&nbsp;The bags must be in the jar to protect the tablets and should not be swallowed.<\/p>\n\n\n\n<p>The following pack sizes are available:<\/p>\n\n\n\n<p>Outer cartons containing 1 jar of 30 film-coated tablets.<\/p>\n\n\n\n<p>Outer cartons containing 3 cans of 30 film-coated tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Glenmark Arzneimittel GmbH, Industriestr.&nbsp;31, 82194 Gr\u00f6benzell, Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Glenmark Pharmaceuticals sro, Fibichova 143, 566 17 Vysok\u00e9 M\u00fdto, Czech Republic<\/p>\n\n\n\n<p>Glenmark Arzneimittel GmbH, Industriestr.&nbsp;31, 82194 Gr\u00f6benzell, Germany<\/p>\n\n\n\n<p>Pharmadox Healthcare Ltd, KW20A Kordin Industrial Park, Paola PLA 3000, Malta<\/p>\n","protected":false},"excerpt":{"rendered":"<p>245 mg\u00a0film-coated tablets<br \/>\ntenofovir disoproxil<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[3389,25592,25596,25594,4331,4332,4330,25593,25595,13322],"class_list":["post-24664","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-tenofovir-disoproxil","tag-tenofovir-disoproxil-glenmark","tag-tenofovir-disoproxil-glenmark-side-effects","tag-tenofovir-disoproxil-glenmark-tablet","tag-tenofovir-disoproxil-side-effects","tag-tenofovir-disoproxil-tablet","tag-what-is-tenofovir-disoproxil","tag-what-is-tenofovir-disoproxil-glenmark","tag-what-tenofovir-disoproxil-glenmark-is-used-for","tag-what-tenofovir-disoproxil-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24664","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=24664"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24664\/revisions"}],"predecessor-version":[{"id":24706,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24664\/revisions\/24706"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=24664"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=24664"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=24664"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}