{"id":24620,"date":"2022-08-26T10:55:51","date_gmt":"2022-08-26T10:55:51","guid":{"rendered":"https:\/\/zeepedia.com\/?p=24620"},"modified":"2023-02-22T15:42:25","modified_gmt":"2023-02-22T15:42:25","slug":"temomedac","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/temomedac\/","title":{"rendered":"Temomedac &#8211; Temozolomide Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Temomedac 5 mg, 20 mg, 100 mg, 140 mg, 180 mg, 250 mg&nbsp;Temozolomide Hard Capsules<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Is Temomedac, And What Temomedac Used For?<\/h2>\n\n\n\n<p>Temomedac contains the medicine temozolomide.\u00a0<strong>Temomedac used for\u00a0tumors.<\/strong> This medicine is used to treat specific forms of brain tumors:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>In adults with newly diagnosed\u00a0glioblastoma multiforme.\u00a0Temomedac is first used together with radiation (concomitant treatment phase) and then alone (the monotherapy phase of treatment).<\/li><li>In children over 3 years and adult patients with malignant\u00a0gliomas, such as\u00a0glioblastoma multiforme\u00a0or\u00a0anaplastic astrocytoma.\u00a0This medicine  is used for these\u00a0tumors\u00a0if they return or continue to develop after standard treatment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What You Need To Know Before Taking Temomedac<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Take Temomedac<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to temozolomide or any of the other ingredients of this medicine (listed in section 6)<\/li><li>If you have had an\u00a0allergic reaction\u00a0to dacarbazine (an anti-cancer medicine, sometimes called DTIC).\u00a0Signs of\u00a0an allergic reaction\u00a0include:<ul><li>Feeling\u00a0itchy<\/li><li>Shortness of breath or wheezing<\/li><li>Swelling of the face, lips, tongue, or throat<\/li><\/ul><\/li><li>If certain types of\u00a0blood cells\u00a0are greatly reduced (myelosuppression), such as the white\u00a0blood cells\u00a0or platelets.\u00a0These\u00a0blood cells\u00a0are important when it comes to fighting\u00a0infection\u00a0and for functioning blood coagulation.\u00a0Your doctor will check your blood to make sure you have enough of these\u00a0blood cells\u00a0before you start treatment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Precautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before taking Temomedac.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Because you should be closely monitored for developing a serious form of\u00a0pneumonia\u00a0called\u00a0<em>Pneumocystis jirovecii\u00a0<\/em>pneumonia\u00a0(PCP), if you have recently received your diagnosis (\u00a0glioblastoma multiforme\u00a0), you may receive Temomedac for 42 days in combination with radiation.\u00a0If so, your doctor will also prescribe medication to help you prevent this type of\u00a0pneumonia\u00a0(PCP).<\/li><li>If you have ever had or possibly now have\u00a0hepatitis\u00a0B\u00a0infection. Temomedac can cause\u00a0hepatitis\u00a0B to become active again, and in some cases, this can lead to death.\u00a0Patients will be carefully examined by their doctor for signs of this\u00a0infection\u00a0before starting treatment.<\/li><li>If you have low numbers of\u00a0red blood cells\u00a0(anemia),\u00a0white blood cells\u00a0and\u00a0platelets\u00a0(\u00a0thrombocytes\u00a0), or blood clotting problems before starting treatment, or if you develop them during treatment.\u00a0Your doctor may decide to lower the\u00a0dose, stop it, or change treatment. You may also need other treatments.\u00a0In some cases, it may be necessary to discontinue treatment with this medicine.\u00a0Your blood will be tested regularly during treatment to monitor the\u00a0side effects\u00a0of Temomedac on your\u00a0blood cells.<\/li><li>As you may have a small risk of other\u00a0blood cell\u00a0changes, including\u00a0leukemia,<\/li><li>If you experience nausea and vomiting, which are very common\u00a0side effects\u00a0of Temomedac (see section 4), your doctor may prescribe medicine (an\u00a0antiemetic\u00a0) to prevent vomiting.<\/li><li>If you frequently vomit before and during treatment, ask your doctor when it is best to take Temomedac until the vomiting is under control.\u00a0If you vomit after taking your\u00a0dose, do not take a second\u00a0dose\u00a0on the same day.<\/li><li>If you develop a fever or symptoms of an\u00a0infection, contact your doctor immediately.<\/li><li>If you are over 70, you may be more susceptible to infection, bruise, or bleeding more easily.<\/li><li>If you have liver or kidney problems, your Temomedac\u00a0dose\u00a0may need to be adjusted.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People<\/h2>\n\n\n\n<p>Do not give this medicine to children younger than 3 years because there is no experience.\u00a0There is limited information on patients older than 3 years who have taken this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Temomedac<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding, And Fertility<\/h2>\n\n\n\n<p>If you are pregnant, think you may be pregnant, or plan to have a baby, ask your doctor or pharmacist for advice before using this medicine.\u00a0You should not be treated with Temomedac if you are pregnant unless your doctor tells you so.<\/p>\n\n\n\n<p>Effective contraceptive methods must be used by female patients who may become pregnant during treatment with this medicine and for at least 6 months after stopping treatment. You should stop breastfeeding while receiving treatment with this medicine.<\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Male\u00a0fertility<\/span><\/strong>:<\/p>\n\n\n\n<p>Temomedac can cause permanent&nbsp;infertility.&nbsp;Male patients should use an effective method of contraception and not have children for at least 3 months after the end of treatment.&nbsp;It is recommended to consult about sperm freezing before starting treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving Ability And Use Of Machinery:<\/h2>\n\n\n\n<p>This medicine may make you feel tired or sleepy.\u00a0If this is the case, do not drive, use machinery, or cycle until you know how this medicine affects you (see section 4).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Temomedac Contains lactose<\/h2>\n\n\n\n<p>Temomedac contains\u00a0lactose\u00a0(a type of sugar).\u00a0If you are intolerant to certain sugars, you should consult your doctor before taking this medication.<\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Temomedac contains\u00a0sodium<\/span><\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)\u00a0of sodium\u00a0per hard capsule, i.e., it is almost &#8216;sodium-free.&#8217;<\/p>\n\n\n\n<p><em><strong><span style=\"text-decoration: underline;\">Additional information for Temomedac 20 mg hard capsules<\/span><\/strong><\/em><\/p>\n\n\n\n<p>The additive para-orange (E 110) found in the capsule shell can cause allergic reactions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How To Take Temomedac?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Always take this medicine as directed by your doctor or pharmacist.\u00a0Ask your doctor or pharmacist if you are unsure.<\/li><li><strong>Dosage\u00a0and duration of treatment<\/strong><ul><li>Your doctor will determine the Temomedac\u00a0dose.\u00a0It is based on your body size (height and weight) and whether you have a recurrent\u00a0tumor\u00a0and have previously received\u00a0chemotherapy.<\/li><li>You may be prescribed other medicines (antiemetics) to be taken before and after you take this medicine to prevent or control nausea and vomiting.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><em><u>Patients with newly diagnosed&nbsp;glioblastoma multiforme<\/u><\/em><\/p>\n\n\n\n<p>If you are a newly diagnosed patient, the treatment will take place in two phases:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Treatment together with radiation (concurrent phase) first<\/li><li>Followed by treatment with Temomedac alone (monotherapy phase).<\/li><\/ul>\n\n\n\n<p>During the concurrent phase, your doctor will start you with Temomedac at 75 mg\/m\u00a02\u00a0(usual\u00a0dose\u00a0).\u00a0With radiotherapy, you will take this dose daily for 42 days (up to 49 days).<\/p>\n\n\n\n<p>Temomedac\u00a0dose\u00a0one can be postponed or interrupted depending on your blood values \u200b\u200band how well you tolerate the drug during the concurrent phase. When the radiation treatment is finished, you will have a treatment break of 4 weeks.\u00a0It will allow your body to recover.<\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">You will then begin the monotherapy phase.<\/span><\/strong><\/p>\n\n\n\n<p>During the monotherapy phase, the\u00a0dose\u00a0and how you take Temomedac will differ.\u00a0Your doctor will work out exactly what\u00a0amount\u00a0you should have.\u00a0You can have up to 6 treatment periods (cycles).\u00a0Each of these lasts for 28 days.\u00a0You will take only the new\u00a0dose\u00a0once a day for the first 5 days (\u201cdosing days\u201d) of each cycle.<\/p>\n\n\n\n<p>The first\u00a0dose\u00a0will be 150 mg\/m\u00a02.\u00a0After that, you will have 23 days without Temomedac.\u00a0In total, there will be a 28-day treatment cycle.<\/p>\n\n\n\n<p>After day 28, the next cycle begins.\u00a0You will again take Temomedac once a day for 5 days, followed by 23 days without Temomedac.\u00a0The dose\u00a0of this medicine can be adjusted, postponed, or discontinued depending on your blood levels and how well you tolerate the medicine during each treatment cycle.<\/p>\n\n\n\n<p><em><strong>Patients with\u00a0tumors\u00a0that have come back or worsened (malignant\u00a0glioma, such as\u00a0glioblastoma multiforme\u00a0or\u00a0anaplastic astrocytoma\u00a0) receiving Temomedac alone<\/strong><\/em><\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">A treatment cycle with Temomedac lasts 28 days.<\/span><\/strong><\/p>\n\n\n\n<p>You will take Temomedac alone once daily for the first 5 days.&nbsp;The daily&nbsp;dose&nbsp;depends on whether you have previously received&nbsp;chemotherapy&nbsp;or not.<\/p>\n\n\n\n<p>If you have not previously been treated with\u00a0chemotherapy, the first\u00a0dose\u00a0of Temomedac will be 200 mg\/m\u00a02\u00a0once daily for the first 5 days.\u00a0If you have previously been treated with\u00a0chemotherapy, the first\u00a0dose\u00a0of this medicine will be 150 mg\/m\u00a0<sup>2<\/sup>\u00a0once daily for the first 5 days.\u00a0After that, you will have 23 days without this medicine.\u00a0In total, there will be a treatment cycle of 28 days.<\/p>\n\n\n\n<p>After day 28, the next treatment cycle begins.\u00a0You will again receive Temomedac once daily for 5 days, followed by 23 days without this medicine.<\/p>\n\n\n\n<p>Before each new treatment cycle, your blood will be tested to see if the Temomedac&nbsp;dose&nbsp;needs to be adjusted.&nbsp;Depending on the results of your blood tests, your doctor may adjust the&nbsp;dosage&nbsp;from one to the next cycle.<\/p>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">How to take Temomedac<\/span><\/strong>?<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Take the prescribed\u00a0dose\u00a0of this medicine once a day, preferably at the same time each day.<\/li><li>Take the capsules on an empty stomach;\u00a0for example, at least one hour before breakfast.<\/li><li>Swallow the capsule(s) whole together with a glass of water.\u00a0Do not open, crush or chew the capsules.\u00a0If a capsule is broken, avoid the powder coming into contact with the skin, eyes, or nose.\u00a0If you accidentally get something in your eyes or nose, rinse with water.<\/li><li>Depending on your prescribed dose, you may need to take several capsules simultaneously, possibly in different strengths (the active substance in mg).\u00a0The capsule&#8217;s lid&#8217;s color differs for the different Strengths (see the table below).<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Strength<\/td><td>Color\/marking<\/td><\/tr><tr><td>Temomedac 5 mg<\/td><td>Two stripes in green ink on the upper part and &#8220;T 5 mg&#8221; in green ink on the lower part.<\/td><\/tr><tr><td>Temomedac 20 mg<\/td><td>Two stripes with orange ink on the upper part and &#8220;T 20 mg&#8221; with orange ink on the lower part<\/td><\/tr><tr><td>Temomedac 100 mg<\/td><td>Two stripes with pink ink on the upper part and &#8220;T 100 mg&#8221; with pink ink on the lower part<\/td><\/tr><tr><td>Temomedac 140 mg<\/td><td>Two stripes in blue ink on the upper part and &#8220;T 140 mg&#8221; in blue ink on the lower part<\/td><\/tr><tr><td>Temomedac 180 mg<\/td><td>Two stripes in red ink on the upper part and &#8220;T 180 mg&#8221; in red ink on the lower part<\/td><\/tr><tr><td>Temomedac 250 mg<\/td><td>Two stripes in black ink on the upper part and &#8220;T 250 mg&#8221; in black ink on the lower part<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Make sure you understand exactly and remember the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>How many capsules do you need to take each dosing day?\u00a0Ask your doctor or pharmacist to write it down (including the color).<\/li><li>Which days are your dosing days?<\/li><\/ul>\n\n\n\n<p>Review the\u00a0dosage\u00a0with your doctor each time you start a new treatment, as it may differ from the previous period.<\/p>\n\n\n\n<p>Always take this medicine as directed by your doctor.\u00a0Ask your doctor or pharmacist if you are unsure.\u00a0Mistakes in how you take your medication can have serious consequences on your health.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Have Taken Too Much Temomedac:<\/h2>\n\n\n\n<p>If you accidentally take more capsules than prescribed, contact your doctor, pharmacist or nurse immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Take Temomedac:<\/h2>\n\n\n\n<p>Take the missed\u00a0dose\u00a0as soon as possible on the same day.\u00a0If a day has already passed, contact your doctor.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose unless your doctor has told you to do so. Contact your doctor, pharmacist, or nurse if you have further questions about this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible Temomedac Side Effects:<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them. Contact your doctor\u00a0<strong>immediately<\/strong>\u00a0if you experience any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>A severe allergic (hypersensitivity) reaction (\u00a0hives, wheezing, or other breathing difficulties)<\/li><li>Uncontrolled bleeding<\/li><li>Seizures (convulsions)<\/li><li>Fever<\/li><li>Chills<\/li><li>Severe headache that does not go away<\/li><\/ul>\n\n\n\n<p>Treatment with this medicine can cause a reduction in certain types of\u00a0blood cells.\u00a0This may mean you bruise or bleed more easily,\u00a0have anemia\u00a0(lack of\u00a0red blood cells\u00a0), fever, and reduced resistance to\u00a0infection.\u00a0The reduced number of\u00a0blood cells\u00a0is usually transient.<\/p>\n\n\n\n<p>In some cases, it can be more prolonged and lead to a very severe form of\u00a0anemia\u00a0(aplastic\u00a0anemia\u00a0).\u00a0Your doctor will measure your blood levels regularly to detect changes and determine if special treatment is required.\u00a0Sometimes, your\u00a0dose\u00a0ofthis medicine may be reduced, or treatment may be stopped.<\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;that have been reported are listed below:<\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 in 10 users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Loss of appetite<\/li><li>Difficulty speaking<\/li><li>Headache<\/li><li>Vomiting<\/li><li>Nausea<\/li><li>Diarrhea<\/li><li>Constipation<\/li><li>Rash<\/li><li>Hair loss<\/li><li>Fatigue<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 users)<\/strong>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Infection,\u00a0infection\u00a0in the oral cavity<\/li><li>Reduced number of\u00a0blood cells\u00a0(\u00a0neutropenia, lymphopenia,\u00a0thrombocytopenia\u00a0)<\/li><li>Allergic reaction<\/li><li>Elevated blood sugar<\/li><li>Impaired memory<\/li><li>Depression<\/li><li>Anxiety<\/li><li>Confusion<\/li><li>Inability to fall asleep or stay asleep<\/li><li>Impaired coordination and balance<\/li><li>Difficulty concentrating<\/li><li>Changes in mood or attention<\/li><li>Forgetfulness<\/li><li>Dizziness<\/li><li>Impaired sensation<\/li><li>Tingling<\/li><li>Tremors<\/li><li>Changes in taste<\/li><li>Partial\u00a0vision loss<\/li><li>Abnormal vision<\/li><li>Double vision<\/li><li>Painful eyes<\/li><li>dDeafness<\/li><li>Ringing in the ears<\/li><li>Earache<\/li><li>Blood clots in the lungs or legs<\/li><li>High\u00a0blood pressure<\/li><li>Pneumonia<\/li><li>Shortness of breath<\/li><li>Bronchitis<\/li><li>Cough<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sinusitis\/\">Sinusitis<\/a><\/li><li>Stomach or abdominal pain<\/li><li>Upset stomach\/heartburn<\/li><li>Difficulty swallowing<\/li><li>Dry skin<\/li><li>Itching<\/li><li>Muscle damage<\/li><li>Muscle weakness<\/li><li>Muscle aches and pains<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">Joint pain<\/a><\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/back-hurts\/\">Back pain<\/a><\/li><li>Frequent urges to urinate<\/li><li>Difficulty holding tight<\/li><li>Fever,\u00a0flu-like symptoms<ul><li>Aches<\/li><li>Malaise<\/li><li>Cold or\u00a0flu<\/li><\/ul><\/li><li>Fluid retention, leg swelling<\/li><li>Elevated levels of liver enzymes<\/li><li>Weight loss<\/li><li>Weight gain<\/li><li>Radiation damage<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 users)<\/strong>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Infection\u00a0in the brain (meningoencephalitis caused by the herpes virus), which can be fatal<\/li><li>New or reactivated (recurrent)\u00a0infection\u00a0with\u00a0cytomegalovirus<\/li><li>Wound infections<\/li><li>Reactivated\u00a0hepatitis\u00a0B virus infections<\/li><li>Secondary cancer, including\u00a0leukemia<\/li><li>Reduced number of\u00a0blood cells\u00a0(pancytopenia,\u00a0anemia,\u00a0leukopenia\u00a0)<\/li><li>Red dots under the skin<\/li><li>Diabetes insipidus\u00a0(symptoms include increased urine output and thirst), low blood potassium levels<\/li><li>Mood swings<\/li><li>Hallucinations<\/li><li>Partial\u00a0paralysis<\/li><li>Changes in the sense of smell<\/li><li>Dry eyes<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/impaired-hearing\/\">Impaired hearing<\/a><\/li><li>Infection\u00a0in the middle ear<\/li><li>Palpitations (you can feel the heartbeat)<\/li><li>Hot flushes<\/li><li>Bloated stomach<\/li><li>Difficulty controlling bowel movements<\/li><li>Hemorrhoids<\/li><li>Dry mouth<\/li><li>Liver inflammation and liver damage (including fatal liver failure), cholestasis, increased level of\u00a0bilirubin<\/li><li>Blisters on the body or in the mouth, scaly skin, skin reactions<\/li><li>Painful reddening of the skin<\/li><li>A severe rash with skin swelling (on the palms of the hands and soles of the feet)<\/li><li>Increased sensitivity to sunlight,\u00a0urticaria\u00a0(hives)<\/li><li>Increased sweating<\/li><li>Change in skin color<\/li><li>Difficulty urinating<\/li><li>Vaginal bleeding<\/li><li>Vaginal irritation<\/li><li>Missed or heavy periods<\/li><li>Pain in the breasts<\/li><li>Sexual\u00a0impotence<\/li><li>Tremors<\/li><li>Swelling of the face<\/li><li>Discoloration of the tongue<\/li><li>Thirst<\/li><li>Toothache<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How To Store Temomedac?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children, preferably in a locked cabinet.\u00a0Accidental ingestion can be fatal for children.<\/li><li>Use before the expiry date stated on the label and carton.\u00a0The expiration date is the last day of the specified month.<\/li><li>Store at a maximum of 30 \u00b0C.<\/li><li>Store in the original packaging.\u00a0Moisture sensitive.<\/li><li>Close the jar well.<\/li><li>Tell the pharmacist if you notice any change in the appearance of the capsules.<\/li><li>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is temozolomide. Temomedac 5 mg hard capsules:\u00a0One capsule contains 5 mg temozolomide.Temomedac 20 mg hard capsules:\u00a0One capsule contains 20 mg temozolomide.Temomedac 100 mg hard capsules:\u00a0One capsule contains 100 mg temozolomide.Temomedac 140 mg hard capsules:\u00a0One capsule contains 140 mg temozolomide.Temomedac 180 mg hard capsules:\u00a0One capsule contains 180 mg temozolomide.Temomedac 250 mg hard capsules:\u00a0One capsule contains 250 mg temozolomide.<\/li><li>Other ingredients are Contents of the capsule:<br>Anhydrous\u00a0lactose, sodium starch glycolate, silicon dioxide, tartaric acid, and stearic acid (see section 2, &#8220;Temomedac contains lactose&#8221;).The capsule casing (including printing ink): Temomedac 5 mg hard capsules:\u00a0gelatin, titanium dioxide (E 171), shellac, propylene glycol, indigo carmine (E 132), aluminum lake, yellow iron oxide (E 172).Temomedac 20 mg hard capsules:\u00a0gelatin, titanium dioxide (E 171), shellac, propylene glycol, para-orange aluminum lake (E 110).Temomedac 100 mg hard capsules:\u00a0gelatin, titanium dioxide (E 171), red iron oxide (E 172), shellac, propylene glycol, yellow iron oxide (E 172).Temomedac 140 mg hard capsules:\u00a0gelatin, titanium dioxide (E 171), shellac, propylene glycol, indigo carmine (E 132), aluminum lake.<em>Temomedac 180 mg hard capsules:<\/em>\u00a0gelatin, titanium dioxide (E 171), shellac, propylene glycol, red iron oxide (E 172)<em>Temomedac 250 mg hard capsules:<\/em>\u00a0gelatin, titanium dioxide (E 171), shellac, propylene glycol, black iron oxide (E 172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance And Package Sizes Of The Medicine<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Temomedac 5 mg hard capsules\u00a0have a white opaque body and body.\u00a0The upper part is marked with 2 stripes in green ink, and the lower part is marked with \u201cT 5 mg\u201d in green ink.<\/li><li>Temomedac 20 mg hard capsules\u00a0have a white opaque body and body.\u00a0The upper part is marked with 2 stripes in orange ink, and the lower part is marked with \u201cT 20 mg\u201d in orange ink.<\/li><li>Temomedac 100 mg hard capsules\u00a0have a white opaque body and body.\u00a0The upper part is marked with 2 stripes in pink ink, and the lower part is marked with \u201cT 100 mg\u201d in pink ink.<\/li><li>Temomedac 140 mg hard capsules\u00a0have a white opaque body and body.\u00a0The upper part is marked with 2 stripes in blue ink, and the lower part is marked with \u201cT 140 mg\u201d in blue ink.<\/li><li>Temomedac 180 mg hard capsules\u00a0have a white opaque body and body.\u00a0The upper part is marked with 2 stripes in red ink, and the lower part is marked with \u201cT 180 mg\u201d in red ink.<\/li><li>Temomedac 250 mg hard capsules\u00a0have a white opaque body and body.\u00a0The upper part is marked with 2 stripes in black ink, and the lower part is marked with \u201cT 250 mg\u201d in black ink.<\/li><li>The hard capsules for\u00a0oral\u00a0use are supplied in amber glass jars containing 5 or 20 capsules.<\/li><li>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>medac<\/p>\n\n\n\n<p>Gesellschaft f\u00fcr klinische Spezialpr\u00e4parate mbH<\/p>\n\n\n\n<p>Theaterstr.&nbsp;6<\/p>\n\n\n\n<p>22880 Wedel<\/p>\n\n\n\n<p>Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Temomedac is prescribed for treating malignant glioma (brain tumours) in the following patient populations: adults with newly diagnosed glioblastoma multiforme (an aggressive type of brain tumour).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200],"tags":[25550,25527,25547,25549,25531,25529,25546,25526,25548,25530],"class_list":["post-24620","post","type-post","status-publish","format-standard","hentry","category-medicines","tag-benefits-of-temomedac","tag-benefits-of-temozolomide","tag-temomedac","tag-temomedac-side-effects","tag-temozolomide","tag-temozolomide-side-effects","tag-what-is-temomedac","tag-what-is-temozolomide","tag-what-temomedac-is-used-for","tag-what-temozolomide-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24620","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=24620"}],"version-history":[{"count":96,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24620\/revisions"}],"predecessor-version":[{"id":51051,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24620\/revisions\/51051"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=24620"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=24620"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=24620"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}