0.3 mg\/ml\u00a0solution\u00a0for injection
buprenorphine<\/p>\n\n\n\n
Temgesic injection solution is an injection solution that contains buprenorphine and belongs to the group of opioid analgesics.<\/p>\n\n\n\n
Temgesic\u00a0injection\u00a0is a medicine that reduces the pain that occurs after surgery.<\/p>\n\n\n\n
The buprenorphine contained in Temgesic\u00a0solution for injection\u00a0may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have further questions, and always follow their instructions.
<\/p>\n\n\n\n
If you are allergic to buprenorphine or any of the other ingredients of this medicine (listed in section 6).<\/a><\/p>\n\n\n\n Talk to your doctor or pharmacist before using Temgesic solution for injection if you have:<\/p>\n\n\n\n Important things to consider:<\/p>\n\n\n\n Some medicines can increase the\u00a0side effects\u00a0of Temgesic\u00a0solution for injection\u00a0and in some cases can cause very serious reactions.\u00a0Tell your doctor if you are taking, have recently taken, or might take any other medicines.\u00a0Do not take any other medicines while using Temgesic\u00a0solution for injection\u00a0without first talking to your doctor, especially:<\/p>\n\n\n\n Alcohol can cause increased drowsiness and can increase the risk of respiratory failure if taken with a Temgesic\u00a0solution for injection.\u00a0Do not take Temgesic\u00a0solution for injection\u00a0with alcohol or with medicines that contain alcohol.<\/p>\n\n\n\n The risks for pregnant women of using Temgesic solution for injection are not known. Tell your doctor if you are pregnant or planning to have a baby. The doctor will decide whether the treatment should be continued with another medicine.<\/p>\n\n\n\n Medicines such as Temgesic\u00a0solution for injection, if taken during, especially advanced, pregnancy can cause withdrawal symptoms and breathing problems in the newborn baby.\u00a0These problems can occur several days after birth.<\/p>\n\n\n\n Do not breastfeed while taking this medicine because the Temgesic\u00a0solution for injection\u00a0passes into breast milk.<\/p>\n\n\n\n Ask your doctor or pharmacist for advice before taking any medicine.<\/a><\/p>\n\n\n\n You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0A description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n During treatment with a Temgesic\u00a0solution for injection, the ability to react may be prolonged because a Temgesic\u00a0solution for injection\u00a0can cause drowsiness.\u00a0Do not drive or operate machinery, or perform any hazardous activity until you know how this medicine affects you.<\/p>\n\n\n\n If your doctor has told you that you have an intolerance to some sugars, consult your doctor before using this medicine. Always use Temgesic solution for injection as directed by your doctor or pharmacist. Ask your doctor or pharmacist if you are unsure. Do not inject more than the dose your doctor has prescribed for you.<\/strong><\/p>\n\n\n\n The recommended\u00a0dose\u00a0is 0.3-0.6 mg (1-2 ml) given\u00a0intramuscularly\u00a0or slowly\u00a0intravenously.\u00a0Dose\u00a0one can be given every 6-8 hours or as needed according to the doctor’s\u00a0prescription.<\/p>\n\n\n\n If you have ingested too much medicine or if, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n If you or someone else accidentally injects too much Temgesic\u00a0solution for injection, you must seek medical attention immediately for treatment as an overdose of Temgesic\u00a0solution for injection\u00a0can cause serious and life-threatening breathing problems.<\/p>\n\n\n\n Symptoms of overdose may include feeling tired, sleepy, dizzy, sweating, dilated\u00a0pupils\u00a0(characterized by blurred vision and difficulty focusing),\u00a0dry mouth,\u00a0euphoria, hallucinations, shallow breathing, possibly slower heart rate, low\u00a0blood pressure\u00a0(\u00a0hypotension\u00a0), nausea, vomiting or constipation.<\/p>\n\n\n\n Your doctor or nurse will tell you what to do if you miss a\u00a0dose. If you have previously received long-term treatment with this type of medicine and if you stop taking Temgesic\u00a0injection, withdrawal symptoms may occur.\u00a0Tell your doctor if you think this is happening to you.\u00a0Do not change the\u00a0dosage\u00a0or stop taking Temgesic\u00a0solution for injection\u00a0without the consent of your attending physician.<\/p>\n\n\n\n If you have any further questions about this medicine, ask your doctor or pharmacist.<\/a><\/p>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n Tell your doctor<\/strong> or seek medical attention immediately if you experience any of the following symptoms after taking this medicine. These symptoms can be serious and Temgesic solution for injection can cause serious and life-threatening breathing problems:<\/p>\n\n\n\n Other side effects:<\/strong><\/p>\n\n\n\n Very common side effects (may affect more than 1 in 10 patients)<\/em><\/p>\n\n\n\n Sedation, dizziness, nausea<\/p>\n\n\n\n Common side effects (may affect up to 1 in 10 patients):<\/em><\/p>\n\n\n\n Headache, miosis (reduced pupils ), hypoventilation (shallow or slow breathing), vomiting, hyperhidrosis (increased sweating).<\/p>\n\n\n\n Uncommon side effects (may affect up to 1 in 100 patients):<\/em><\/p>\n\n\n\n Confusion,\u00a0euphoria\u00a0(exaggerated feeling of well-being), nervousness, depression, psychotic illness (mental illness causing abnormal thinking and perception), hallucinations, personality change (not feeling like yourself), dysarthria (difficulty speaking),\u00a0paresthesia\u00a0(numbness and tingling),\u00a0coma, tremors, blurred vision,\u00a0diplopia\u00a0(double vision<\/a>), visual impairment<\/a>,\u00a0conjunctivitis\u00a0(eye inflammation<\/a> or infection),\u00a0tinnitus\u00a0(ringing in the ears),\u00a0tachycardia\u00a0(fast heartbeat),\u00a0bradycardia\u00a0(slow heartbeat), cyanosis (blue discoloration of the skin), another degree atrioventricular block (heart rhythm disturbances),\u00a0hypertension(high\u00a0blood pressure\u00a0), pallor (pallor),\u00a0dyspnea\u00a0(shortness of breath),\u00a0apnea\u00a0(stopping breathing),\u00a0dry mouth, constipation,\u00a0dyspepsia\u00a0(indigestion), flatulence,\u00a0pruritus\u00a0(\u00a0itching\u00a0), rash, difficulty urinating,\u00a0asthenia\u00a0(fatigue), fatigue, malaise.<\/p>\n\n\n\n Rare side effects (may affect up to 1 in 1,000 patients):<\/em><\/p>\n\n\n\n Decreased appetite,\u00a0dysphoria\u00a0(depressed mood), aggressiveness, convulsions, coordination difficulties, diarrhea,\u00a0urticaria\u00a0(\u00a0hives\u00a0).<\/p>\n\n\n\n Frequency not known (cannot be estimated from available data):<\/em><\/p>\n\n\n\n Drug dependence, drowsiness, lack of effect, drug interactions.<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n Store at a maximum of 30\u00b0C. Store in the original packaging. Light sensitive.<\/p>\n\n\n\n Use before the expiry date stated on the carton after “EXP”. The expiration date is the last day of the specified month.<\/p>\n\n\n\n Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to deal with medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n The active substance is buprenorphine (as buprenorphine hydrochloride). Each ampoule contains 300 micrograms of buprenorphine.<\/p>\n\n\n\n Other ingredients are glucose monohydrate,\u00a0hydrochloric acid,\u00a0and water for\u00a0injection.<\/p>\n\n\n\n Temgesic\u00a0solution for injection\u00a0is a clear solution packaged in 1 ml\u00a0glass ampoules\u00a0and cartons containing a plastic tray of 5\u00a0ampoules.<\/p>\n\n\n\n Indivior Europe Limited,<\/p>\n\n\n\n 27 Windsor Place,<\/p>\n\n\n\n Dublin 2,<\/p>\n\n\n\n D02 DK44,<\/p>\n\n\n\n Ireland<\/p>\n\n\n\n For further information on this medicine, please contact the marketing authorization holder<\/p>\n\n\n\n Telephone: 020791680<\/p>\n\n\n\n Email: PatientSafetyRoW@indivior.com<\/p>\n","protected":false},"excerpt":{"rendered":" Temgesic\u00a0injection solution\u00a0is an\u00a0injection solution\u00a0that contains buprenorphine and belongs to the group of opioid analgesics.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[19122,25560,3584,3587,25557,25561,8115,8114,25558,25559],"class_list":["post-24614","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-benefits-of-buprenorphine","tag-benefits-of-temgesic","tag-buprenorphine","tag-buprenorphine-side-effects","tag-temgesic","tag-temgesic-side-effects","tag-what-buprenorphine-is-used-for","tag-what-is-buprenorphine","tag-what-is-temgesic","tag-what-temgesic-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24614","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=24614"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24614\/revisions"}],"predecessor-version":[{"id":24661,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24614\/revisions\/24661"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=24614"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=24614"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=24614"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Warnings and precautions<\/h2>\n\n\n\n
This drug may be desirable for patients who abuse prescription medications and should be kept in a safe place to protect it from theft.\u00a0Never give the medicine to anyone else, it can lead to death or injury.<\/li>
Patients have died from respiratory failure (inability to breathe) due to using this medicine incorrectly or taking it in combination with other\u00a0CNS\u00a0depressants such as alcohol,\u00a0benzodiazepines\u00a0(sedatives), or other\u00a0opioids.<\/li>
Temgesic\u00a0solution for injection\u00a0can cause sleep-related breathing problems such as\u00a0sleep apnea\u00a0(pauses in breathing during sleep) and sleep-related\u00a0hypoxemia\u00a0(low oxygen levels in the blood).\u00a0The symptoms can be breathing pauses during sleep, waking up at night due to shortness of breath, difficulty staying asleep, or pronounced fatigue during the day.\u00a0Contact the doctor if you or anyone else observes these symptoms.\u00a0The doctor may consider reducing the\u00a0dose.<\/li>
This medicine can be addictive.<\/li>
symptoms This medicine can cause withdrawal symptoms if you also take other\u00a0opioids\u00a0such as heroin or\u00a0methadone.<\/li>
This medicine may mask the pain which is a sign of certain diseases.\u00a0Remember to inform the doctor that you are using this medicine.<\/li><\/ul>\n\n\n\nOther medicines and Temgesic solutions for injection<\/h2>\n\n\n\n
Temgesic solution for injection with food, drink, and alcohol<\/h2>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n
Driving ability and use of machinery<\/h2>\n\n\n\n
Temgesic solution for injection contains glucose.<\/h2>\n\n\n\n
<\/a><\/p>\n\n\n\nHow to use Temgesic solution for injection<\/h2>\n\n\n\n
If you have used too much Temgesic solution for injection<\/h2>\n\n\n\n
If you forget to take Temgesic solution for injection<\/h2>\n\n\n\n
Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/p>\n\n\n\nIf you stop taking Temgesic solution for injection<\/h2>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
How to store Temgesic solution for injection<\/h2>\n\n\n\n
Contents of the packaging and other information<\/h2>\n\n\n\n
Contents declaration<\/h2>\n\n\n\n
Appearance and package sizes of the medicine<\/h2>\n\n\n\n
Marketing authorization holder and manufacturer<\/h2>\n\n\n\n