{"id":24511,"date":"2022-08-24T11:15:24","date_gmt":"2022-08-24T11:15:24","guid":{"rendered":"https:\/\/zeepedia.com\/?p=24511"},"modified":"2022-08-25T08:12:30","modified_gmt":"2022-08-25T08:12:30","slug":"tegretol","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/tegretol\/","title":{"rendered":"Tegretol &#8211; Carbamazepine uses, dose and side effects"},"content":{"rendered":"\n<p>20 mg\/ml&nbsp;oral&nbsp;suspension<br>carbamazepine<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Tegretol is and what it is used for<\/h2>\n\n\n\n<p>Tegretol belongs to a group of medicines called\u00a0antiepileptics.\u00a0It works by preventing the spread of the signals in the brain that trigger an epileptic seizure, thereby making it more difficult for seizures to occur.<\/p>\n\n\n\n<p>Tegretol is used in the treatment of\u00a0epilepsy, certain forms of facial pain (\u00a0trigeminal neuralgia\u00a0), and alcohol withdrawal.<\/p>\n\n\n\n<p>The carbamazepine contained in Tegretol may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Tegretol<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Tegretol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to carbamazepine, any of the other ingredients of this medicine (listed in section 6) or closely related medicines (e.g. some medicines for depression)<\/li><li>if you suffer from&nbsp;porphyria&nbsp;(disorder in the formation of porphyrin, i.e. a pigment important for liver function and blood formation)<\/li><li>if you have a certain type of heart disease (&nbsp;AV block&nbsp;)<\/li><li>if you previously had a certain type of blood disorder<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Consult your doctor before using Tegretol:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you use antidepressants from the group of\u00a0monoamine oxidase\u00a0inhibitors (\u00a0MAO inhibitors\u00a0).\u00a0Treatment with\u00a0MAO inhibitors\u00a0must have been completed for at least 14 days before you can start treatment with Tegretol.<\/li><li>if you have heart or vascular disease.<\/li><li>if you have kidney or liver disease.<\/li><li>if you have\u00a0glaucoma\u00a0or difficulty passing water (urinating) or experience pain when urinating.<\/li><li>if you have previously shown signs of\u00a0<strong>hypersensitivity<\/strong>\u00a0(got a rash or other signs of\u00a0allergy\u00a0) to the substance oxcarbazepine or\u00a0phenytoin.\u00a0For people who are hypersensitive to carbamazepine, the risk is that about one in four patients (25%) will also have an\u00a0allergic reaction\u00a0to oxcarbazepine (Trileptal).<\/li><li>Contact your doctor if you become pregnant or plan to become pregnant.\u00a0There is a risk of harm to the unborn child if Tegretol is used during pregnancy.\u00a0Women of childbearing potential should use effective contraception during treatment with Tegretol and for two weeks after the last\u00a0dose\u00a0(see section\u00a0Pregnancy and breast-feeding\u00a0).<ul><li>If you\u00a0take hormonal contraceptives, e.g.\u00a0birth control pills, Tegretol can cause your contraceptive to not work.\u00a0Use another or a complementary (non-hormonal) method of contraception while taking Tegretol to prevent unwanted pregnancy.\u00a0Contact your doctor immediately if you experience irregular bleeding or breakthrough bleeding.\u00a0Ask your doctor or another healthcare professional if you have any questions about this.<\/li><\/ul><\/li><li>if you have\u00a0kidney problems\u00a0associated with low sodium levels in the blood, or if you have kidney problems and at the same time take certain medicines that lower the sodium level in the blood (\u00a0diuretics, eg\u00a0hydrochlorothiazide,\u00a0furosemide\u00a0).\u00a0You may need to have a blood test to check the level of sodium in your blood.<\/li><li>if you experience dizziness, drowsiness, reduced\u00a0blood pressure, or confusion due to treatment with Tegretol which may lead to you falling.<\/li><\/ul>\n\n\n\n<p>Serious skin rashes (\u00a0Stevens-Johnson\u00a0syndrome,\u00a0toxic epidermal necrolysis\u00a0) have been reported with the use of carbamazepine.\u00a0It may begin as red-violet target-like or round spots with central blistering, often symmetrically distributed, on the trunk.\u00a0Often the rash can include sores in the mouth, throat, nose, genitals, and conjunctivitis (red and swollen eyes).<\/p>\n\n\n\n<p>These severe skin rashes are often preceded by\u00a0flu-like symptoms such\u00a0as fever, headache, and body aches.\u00a0The rash can develop into extensive blistering over large areas and scaling of the skin or peeling.\u00a0The risk of serious skin side effects occurring is greatest during the first months of treatment.<\/p>\n\n\n\n<p>These serious skin reactions may be more common in people from certain Asian countries (eg, Taiwan, Malaysia, and the Philippines) and patients of Chinese or Thai descent.\u00a0The risk of these\u00a0side effects\u00a0in patients of Han Chinese or Thai origin can be determined by a blood test in these patients.\u00a0Doctors should be able to tell you if a blood test is necessary before you start taking carbamazepine.\u00a0Therefore consult your doctor before starting treatment with Tegretol if you are of Chinese or Thai descent.<\/p>\n\n\n\n<p>If you develop a rash or these skin symptoms described here, stop taking medicines containing carbamazepine and contact your doctor immediately and tell them you are taking this medicine.&nbsp;If you have suffered from&nbsp;Stevens-Johnson&nbsp;syndrome or&nbsp;toxic epidermal necrolysis&nbsp;when using the carbamazepine contained in Tegretol, you must never use medicines containing carbamazepine again.<\/p>\n\n\n\n<p>A small number of people who are treated with anti-epileptic drugs such as&nbsp;carbamazepine have also had thoughts of harming themselves or committing suicide.&nbsp;If you ever have these thoughts, contact your doctor immediately.<\/p>\n\n\n\n<p>As Tegretol can cause\u00a0dry mouth, careful oral hygiene should be observed (tooth brushing with fluoride toothpaste twice daily).<\/p>\n\n\n\n<p><strong>Other medicines and Tegretol<\/strong><\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>If you are using antidepressants from the group of&nbsp;monoamine oxidase&nbsp;inhibitors (&nbsp;MAO inhibitors&nbsp;), that treatment must have ended at least 14 days before you can start taking Tegretol.<\/p>\n\n\n\n<p>The treatment effect can be affected if you take Tegretol together with other medicines.&nbsp;Treating physicians must therefore be aware of&nbsp;<strong>all<\/strong>&nbsp;other medications.&nbsp;This applies to both prescription and non-prescription drugs.&nbsp;In particular, it applies to certain pain-relieving drugs (eg&nbsp;<strong>dextropropoxyphene<\/strong>&nbsp;).&nbsp;But many other different medicines can also mean that your Tegretol&nbsp;dose&nbsp;needs to be adjusted.<\/p>\n\n\n\n<p>In addition, the effect of other medicines can be affected by Tegretol, in particular, this applies to:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sedative drugs (eg midazolam)<\/li><li>heart medicines (eg&nbsp;ivabradine&nbsp;)<\/li><li>cholesterol-lowering drugs (eg&nbsp;simvastatin&nbsp;)<\/li><\/ul>\n\n\n\n<p><strong>Therefore, always tell the doctor who prescribes another medicine for you that you are using Tegretol.<\/strong><\/p>\n\n\n\n<p>Hormonal contraceptives (eg\u00a0birth control pills,\u00a0patches,\u00a0injections,\u00a0or\u00a0implants\u00a0): Tegretol can affect how hormonal contraceptives work and make them less effective at preventing pregnancy.\u00a0Talk to your doctor to choose together the type of contraception that is most suitable when you are taking Tegretol.\u00a0See section\u00a0Warnings and precautions.<\/p>\n\n\n\n<p>Natural remedies containing&nbsp;St. John&#8217;s wort&nbsp;(&nbsp;<em>Hypericum perforatum<\/em>&nbsp;) should not be used during medication with Tegretol.&nbsp;If you are already taking a St. John&#8217;s&nbsp;wort&nbsp;preparation, you should contact your doctor before you stop taking this preparation.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Tegretol with food, drink, and alcohol<\/h2>\n\n\n\n<p>You should not drink alcohol during treatment with Tegretol as the medicine may reduce the ability to tolerate alcohol.<\/p>\n\n\n\n<p>You should not drink grapefruit juice during treatment with Tegretol.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, consult your doctor before using this medicine.<\/p>\n\n\n\n<p>Pregnancy<\/p>\n\n\n\n<p>Tegretol can cause serious birth defects.\u00a0If you take Tegretol during pregnancy, your child is up to 3 times more likely to have a malformation than children of women who do not take any medicine against\u00a0epilepsy.\u00a0Severe malformations have been reported, such as neural tube defects (opening in the spine), malformations of the face (eg, cleft lip and\u00a0palate\u00a0), skull, heart, penis, and urinary opening (hypospadias), and fingers.\u00a0Your unborn baby should be monitored closely if you have taken Tegretol during pregnancy.<\/p>\n\n\n\n<p>Problems with the child&#8217;s neurological development (development of the brain) have been reported in children of women who have used Tegretol during pregnancy.&nbsp;Some studies have shown that carbamazepine negatively affects the neurological development of children exposed to carbamazepine during pregnancy, while other studies have found no such effect.&nbsp;It cannot be ruled out that carbamazepine can affect the child&#8217;s neurological development.<\/p>\n\n\n\n<p>If you are a\u00a0fertile\u00a0woman and do not plan to become pregnant, you must use effective contraception during treatment with Tegretol.\u00a0Tegretol can affect how hormonal contraceptives, e.g.\u00a0birth control pills, work and make them less effective in preventing pregnancy.\u00a0Talk to your doctor, who will discuss with you what type of birth control is most appropriate to use while you are taking Tegretol.\u00a0If treatment with Tegretol is stopped, you must continue to use effective contraception for another two weeks after stopping treatment.<\/p>\n\n\n\n<p>If you are a&nbsp;fertile&nbsp;woman and planning to become pregnant, you should &#8211; before stopping contraception and before becoming pregnant &#8211; talk to your doctor about switching to other suitable treatments.&nbsp;This is to avoid&nbsp;exposing&nbsp;the unborn child to carbamazepine.<\/p>\n\n\n\n<p>If you are pregnant or think you may be pregnant, tell your doctor immediately.&nbsp;Do not stop taking the medicine until you have discussed this with the doctor.&nbsp;If you stop taking the medicine without consulting the doctor, it can cause epileptic seizures which can be dangerous for you and your unborn baby.&nbsp;The doctor may decide that the treatment should be changed.<\/p>\n\n\n\n<p>If you take Tegretol during pregnancy, your baby is also at risk of bleeding problems immediately after birth.\u00a0Your doctor can give you and your child medicine to prevent this.<\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p>Carbamazepine passes into breast milk.&nbsp;Consult a doctor or pharmacist before taking Tegretol while breastfeeding<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Tegretol may make you feel sleepy or dizzy.\u00a0You may also experience blurred vision, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/distinction-and-double-vision-in-adults\/\">double vision<\/a>, or difficulty coordinating muscle movements, especially at the beginning of your treatment or after a dose increase.\u00a0This should therefore be taken into account when increased attention is required, e.g.\u00a0when driving a car or other vehicle, using machinery, or performing other activities that require increased vigilance.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\u00a0side effects.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Tegretol contains sodium, sorbitol (E 420), propylene glycol (E 1520) and parahydroxybenzoates<\/h2>\n\n\n\n<p><em>Sodium:<\/em>&nbsp;This medicine contains less than 1 mmol (23 mg)&nbsp;of sodium&nbsp;per ml, i.e. it is almost &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<p><em>Sorbitol (E 420):<\/em>\u00a0This medicine contains 175 mg of sorbitol per ml\u00a0of oral\u00a0suspension.\u00a0Sorbitol is a source of fructose.\u00a0If you (or your child) have an intolerance to certain sugars, or if you (or your child) have been diagnosed with\u00a0hereditary\u00a0fructose intolerance, a rare, inherited disease that makes it impossible to break down fructose, consult a doctor before using this medicine.<\/p>\n\n\n\n<p>Sorbitol can cause stomach\/intestinal discomfort and can have a mild laxative effect.<\/p>\n\n\n\n<p><em>Propylene glycol (E 1520):<\/em>&nbsp;This medicine contains 25 mg of propylene glycol per ml.<\/p>\n\n\n\n<p>If your child is younger than 4 weeks, consult a doctor or pharmacist before the child uses the medicine, especially if the child uses other medicines that contain propylene glycol or alcohol.<\/p>\n\n\n\n<p><em>Parahydroxybenzoates:<\/em>&nbsp;This medicine contains propyl parahydroxybenzoate and methyl parahydroxybenzoate which can cause&nbsp;an allergic reaction&nbsp;(possibly delayed).<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Tegretol<\/h2>\n\n\n\n<p>Always take this medicine as directed by your doctor.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The dose\u00a0is determined by the doctor, who adjusts it individually for you.\u00a0Carefully follow the doctor&#8217;s\u00a0prescription.\u00a0This is especially important in the case of\u00a0epilepsy\u00a0so that you get adequate seizure protection.\u00a0Initially, a lower\u00a0dose\u00a0is given which is then gradually increased until an effective maintenance dose is reached.<\/p>\n\n\n\n<p><em>Usual maintenance dose for adults<\/em><\/p>\n\n\n\n<p>800-1200 mg per day divided into 2-3 doses.<\/p>\n\n\n\n<p><em>The usual\u00a0dose\u00a0for children<\/em><\/p>\n\n\n\n<p>10-20 mg per kg of body weight per day divided into 2-3 doses.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Tegretol<\/h2>\n\n\n\n<p>Take Tegretol during or after a meal and with some liquid.<\/p>\n\n\n\n<p><em>Shake before use.<\/em><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Tegretol<\/h2>\n\n\n\n<p>If you have ingested too much medicine or, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Tegretol<\/h2>\n\n\n\n<p>If you have forgotten to take a\u00a0dose, take it as soon as you remember.\u00a0However, if it is time for the next\u00a0dose, do not take the one you forgot.\u00a0Continue with your regular dosing schedule.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Tegretol<\/h2>\n\n\n\n<p>When treating\u00a0epilepsy, you should not suddenly stop your medication because the risk of seizures then increases.\u00a0Never change your treatment yourself without consulting your doctor.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be serious.&nbsp;Seek immediate medical attention if you experience any of the following:<\/strong><\/p>\n\n\n\n<p><em>Agranulocytosis&nbsp;(rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>In rare cases, Tegretol can affect the white\u00a0blood cells\u00a0so that the defense against infection deteriorates.\u00a0If you get an\u00a0infection\u00a0with symptoms such as fever with a greatly worsened general condition or fever with local symptoms of infection such as sore throat\/pharynx\/mouth or difficulty urinating, you should see a doctor as soon as possible so that a lack of\u00a0white blood cells\u00a0can be ruled out via a blood test (\u00a0agranulocytosis\u00a0).\u00a0It is important that you then have information about your medication.<\/p>\n\n\n\n<p><em>Angioedema&nbsp;(very rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>Swelling of the face, tongue, or throat;\u00a0difficulty swallowing;\u00a0hives\u00a0and difficulty breathing.<\/p>\n\n\n\n<p><em>Toxic epidermal necrolysis&nbsp;(very rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>Severe widespread skin damage (skin peeling of the epidermis and superficial mucous membranes) see section 2.<\/p>\n\n\n\n<p><em>Stevens-Johnson syndrome&nbsp;(very rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>An extremely strong\u00a0allergic reaction\u00a0with a skin rash is usually in the form of blisters or sores in the oral cavity and eyes as well as other mucous membranes such as the genitals, see section 2.<\/p>\n\n\n\n<p><em>Liver disease (rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>For example.&nbsp;jaundice (yellowing of the skin or whites of the eyes).<\/p>\n\n\n\n<p><em>Decrease in the number of&nbsp;platelets&nbsp;or&nbsp;blood cells&nbsp;(common&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>Showing signs such as tiredness, shortness of breath with light exertion, paleness, headache, chills, dizziness, repeated\u00a0infections\u00a0with fever, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sore-throat\/\">sore throat<\/a>, mouth ulcers, bleeding or bruising that occurs more easily than usual, nosebleeds, reddish or purple-red marks on the skin or unexplained patchy skin rash.<\/p>\n\n\n\n<p><em>SLE&nbsp;-like disease (rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>Causes red, patchy skin rashes, mainly on the face, which can appear at the same time as fatigue, fever, nausea, or loss of appetite.<\/p>\n\n\n\n<p><em>Porphyria disease (rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>This leads to increased excretion of blood dyes in the urine, which becomes dark.<\/p>\n\n\n\n<p><em>Effect on kidney function (rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>Severe decrease in the amount of urine, or blood, in the urine.<\/p>\n\n\n\n<p><em>Pancreatitis (very rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>Severe pain in the upper stomach area, vomiting, loss of appetite<\/p>\n\n\n\n<p><em>Low amount of sodium in the blood (rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>Showing signs such as lethargy, confusion, muscle twitching, or significant worsening of the seizures (these symptoms may be signs of low sodium in the blood)<\/p>\n\n\n\n<p><em>Meningitis&nbsp;(rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>Showing signs such as fever, and nausea.\u00a0Vomiting, headache, stiff neck, and extreme sensitivity to bright light.<\/p>\n\n\n\n<p><em>Neuroleptic malignant syndrome (very rare&nbsp;side effect&nbsp;):<\/em><\/p>\n\n\n\n<p>Causes a sudden rise in body temperature, very high\u00a0blood pressure,\u00a0and severe convulsions.<\/p>\n\n\n\n<p><em>Cardiac effects (rare\u00a0side effects\u00a0):<\/em><\/p>\n\n\n\n<p>For example.&nbsp;irregular heartbeat, chest pain.<\/p>\n\n\n\n<p><em>Colon inflammation (has been reported):<\/em><\/p>\n\n\n\n<p>Showing signs such as diarrhea, abdominal pain, and fever.<\/p>\n\n\n\n<p><em>Cases (have been reported):<\/em><\/p>\n\n\n\n<p>If you fall due to dizziness, drowsiness, decreased\u00a0blood pressure, or confusion.<\/p>\n\n\n\n<p><strong>The following&nbsp;side effects&nbsp;can also occur when using Tegretol:<\/strong><\/p>\n\n\n\n<p><em>Very common<\/em>&nbsp;(may affect more than 1 in 10 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Difficulty coordinating muscle movements, dizziness<\/li><li>Vomiting, nausea<\/li><li>Fatigue<\/li><li>Elevated liver function values<\/li><\/ul>\n\n\n\n<p><em>Common<\/em>&nbsp;(may affect up to 1 in 10 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Increase in the number of\u00a0blood\u00a0cells<\/li><li>Fluid retention\u00a0decreased appetite<\/li><li>Double vision, difficulty seeing up close<\/li><li>Dry mouth<\/li><li>Hives, skin rash<\/li><li>Elevation of certain\u00a0enzymes\u00a0(alkaline phosphatases) in the blood<\/li><\/ul>\n\n\n\n<p><em>Uncommon<\/em>&nbsp;(may affect up to 1 in 100 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache, involuntary movements (eg tremors, twitching), eye twitching (&nbsp;nystagmus&nbsp;), painful facial movements<\/li><li>Diarrhea, constipation<\/li><\/ul>\n\n\n\n<p><em>Rare<\/em>&nbsp;(may affect up to 1 in 1,000 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Delayed hypersensitivity reaction<\/li><li>Breast enlargement in men, milk flow from the breasts even without breastfeeding<\/li><li>Folate deficiency<\/li><li>Hallucinations, depression, aggression, violent agitation, restlessness, confusion, and activation of psychotic symptoms<\/li><li>Eye movement disorder, speech disorders, nerve inflammation in the arms and legs, ants crawling, muscle weakness<\/li><li>Clouding of the eye lens, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/eye-inflammation-in-children\/\">eye inflammation<\/a><\/li><li>Tinnitus, increased sensitivity to sound<\/li><li>Increase or decrease in\u00a0blood pressure\u00a0et,\u00a0inflammation\u00a0of a blood vessel that causes pain (\u00a0thrombophlebitis\u00a0)<\/li><li>Allergic lung problems that may resemble\u00a0pneumonia,<\/li><li>Abdominal pain, taste disturbances,\u00a0inflammation\u00a0of the tongue or oral mucosa<\/li><li>Allergic skin reactions,\u00a0hypersensitivity reaction\u00a0to sunlight, changed skin pigmentation, small bleeding in the skin,\u00a0itching,\u00a0acne, sweating, hair loss, increased hair (including women)<\/li><li>Calcification of bone tissue and osteoporosis after long-term treatment, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">joint pain<\/a>, muscle pain, muscle cramps<\/li><li>Difficulty or increased need to pass water<\/li><li>Sexual disability<\/li><li>Fever decreased thyroid function<\/li><\/ul>\n\n\n\n<p><em>Very rare<\/em>&nbsp;(may affect up to 1 in 10,000 users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/impaired-hearing\/\">Impaired hearing<\/a>, change in tone perception<\/li><li>Increase in breast milk&nbsp;stimulating hormone&nbsp;(&nbsp;prolactin&nbsp;) in the blood<\/li><\/ul>\n\n\n\n<p><em>Has been reported<\/em>&nbsp;(occurring in an unknown number of users)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Anemia is, a reduced number of\u00a0antibodies\u00a0(gammaglobulin) in the blood<\/li><li>Male\u00a0infertility<\/li><li>Increased pressure in the eye<\/li><li>Reactivation of\u00a0human herpesvirus 6 infections, bone marrow\u00a0failure<\/li><li>Sedation, memory impairment<\/li><li>Hypersensitivity syndrome involves\u00a0an allergic reaction\u00a0with rash, fever, and abnormal blood values \u200b\u200b(DRESS)<\/li><li>AGEP (\u00a0acute\u00a0generalized exanthematous\u00a0pustulosis\u00a0) can present with a sudden onset of fever with large\u00a0reddened, small heavily red-dotted rashes, with very small blisters<\/li><li>Thickening of the skin, loss of nails,\u00a0fracture<\/li><li>High levels of ammonia in the blood (hyperammonemia).\u00a0Symptoms of hyperammonemia may include irritability, confusion, vomiting, loss of appetite, and sleepiness.<\/li><\/ul>\n\n\n\n<p>There have been reports of bone diseases, e.g.\u00a0reduced bone density in the skeleton, osteoporosis, and bone fractures.\u00a0Contact a doctor or pharmacist if you are being treated with epilepsy medicine for a long time, if you know you have osteoporosis or if you are\u00a0taking steroids.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Tegretol<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Store in the original packaging.&nbsp;Light sensitive.<\/p>\n\n\n\n<p>Use before the expiry date stated on the packaging after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to dispose of medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is carbamazepine 20 mg\/ml.<\/li><li>Other ingredients are microcrystalline cellulose, carmellose sodium, caramel flavor 52929A (flavor), methyl parahydroxybenzoate (E 218), macrogol stearate, propylene glycol (E 1520), propyl parahydroxybenzoate (E 216), saccharin sodium, sorbic acid (\u00a0preservative\u00a0), liquid sorbitol (E 420) (non- crystallizing), hydroxyethyl cellulose and water.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Tegretol\u00a0oral\u00a0suspension\u00a0is white.<\/p>\n\n\n\n<p>Tegretol\u00a0oral\u00a0suspension\u00a0is supplied in an amber glass bottle containing 300 ml of\u00a0oral\u00a0suspension.\u00a0Measuring spoon 5 ml (graduated 1.25; 2.5 and 5 ml) included.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>20 mg\/ml\u00a0oral\u00a0suspension<br \/>\ncarbamazepine.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[13792,25410,13788,13793,25406,25409,13790,13789,25408,25407],"class_list":["post-24511","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-benefits-of-carbamazepine","tag-benefits-of-tegretol","tag-carbamazepine","tag-carbamazepine-side-effects","tag-tegretol","tag-tegretol-side-effects","tag-what-carbamazepine-is-used-for","tag-what-is-carbamazepine","tag-what-is-tegretol","tag-what-tegretol-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24511","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=24511"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24511\/revisions"}],"predecessor-version":[{"id":24551,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24511\/revisions\/24551"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=24511"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=24511"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=24511"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}