{"id":24420,"date":"2022-08-23T12:55:33","date_gmt":"2022-08-23T12:55:33","guid":{"rendered":"https:\/\/zeepedia.com\/?p=24420"},"modified":"2022-08-24T10:53:38","modified_gmt":"2022-08-24T10:53:38","slug":"taptiqom-sine","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/taptiqom-sine\/","title":{"rendered":"Taptiqom sine &#8211; Tafluprost\/timolol uses, dose and side effects"},"content":{"rendered":"\n<p>15 micrograms\/ml + 5 mg\/ml&nbsp;eye drops&nbsp;, solution<br>tafluprost\/timolol<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Taptiqom sine is and what it is used for<\/h2>\n\n\n\n<p><strong>What kind of medicine is it and how does it work?<\/strong><\/p>\n\n\n\n<p>Taptiqom\u00a0eye drops\u00a0contain tafluprost and\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/timosan\/\">timolol<\/a>.\u00a0Tafluprost belongs to a group of medicines called\u00a0prostaglandin analogs\u00a0and\u00a0timolol\u00a0belongs to a group of medicines called\u00a0beta blockers.\u00a0Tafluprost and\u00a0timolol\u00a0work together to lower the pressure in the eye.\u00a0Taptiqom sine is used when the pressure in the eye is too high.<\/p>\n\n\n\n<p><strong>What is your medicine for?<\/strong><\/p>\n\n\n\n<p>Taptiqom sine is used to treat a type of&nbsp;glaucoma&nbsp;called&nbsp;open-angle glaucoma&nbsp;and also a condition called&nbsp;ocular&nbsp;hypertension&nbsp;in adults.&nbsp;Both of these conditions are associated with increased pressure in the eye and can ultimately affect your vision.<\/p>\n\n\n\n<p>Tafluprost and\u00a0timolol\u00a0found in Taptiqom sine may also be approved to treat other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Taptiqom sine<\/h2>\n\n\n\n<p><strong>Do not use Taptiqom sine<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to tafluprost,\u00a0timolol,\u00a0beta-blockers,\u00a0or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have or have previously had problems with breathing such as\u00a0asthma, severe\u00a0chronic\u00a0obstructive\u00a0bronchitis\u00a0(severe lung disease that can cause wheezing, difficulty breathing, and\/or prolonged coughing)<\/li><li>if you have a slow heart rhythm,\u00a0heart failure,\u00a0or heart rhythm disturbances (irregular heart rhythm).<\/li><\/ul>\n\n\n\n<p><strong>Warnings and precautions<\/strong><\/p>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using Taptiqom sine.<\/p>\n\n\n\n<p><strong>Talk to your doctor before using this medicine if you have or have ever had:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>coronary heart disease (symptoms may include chest pain, chest tightness, shortness of breath, or feeling of suffocation),\u00a0heart failure, low\u00a0blood pressure<\/li><li>heart rhythm disturbances, such as slow heart rate<\/li><li>breathing problems,\u00a0asthma,\u00a0or\u00a0chronic obstructive pulmonary disease<\/li><li>disease with poor blood circulation (such as\u00a0Raynaud&#8217;s disease\u00a0or Raynaud&#8217;s syndrome)<\/li><li>diabetes, as\u00a0timolol\u00a0may mask signs and symptoms of low blood sugar<\/li><li>an overactive\u00a0thyroid, as\u00a0timolol\u00a0may mask signs and symptoms of thyroid disease<\/li><li>allergy\u00a0or anaphylactic reactions<\/li><li>myasthenia gravis\u00a0(a rare disease that causes muscle weakness)<\/li><li>other eye diseases, such as diseases of the cornea (the transparent membrane that covers the front of the eye) or a disease that requires eye surgery.<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor if you have<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>kidney problems<\/li><li>liver problems.<\/li><\/ul>\n\n\n\n<p><strong>Please note<\/strong>&nbsp;that Taptiqom sine may have the following effects and some of them may be permanent:<\/p>\n\n\n\n<p>Taptiqom sine can<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increase the length, thickness, color, and\/or a number of eyelashes and may cause abnormal hair growth on your eyelids.<\/li><li>darken the skin around the eyes.\u00a0Wipe off any solution that may have ended up on the skin.\u00a0This reduces the risk of skin darkening.<\/li><li>change the color of the\u00a0iris\u00a0(the colored part of your eye).\u00a0If Taptiqom sine is used in only one eye, the color of the treated eye may be permanently different from the color of the other eye.<\/li><li>cause hair growth on areas where the solution repeatedly comes into contact with the skin surface.<\/li><\/ul>\n\n\n\n<p>Before having an operation, tell your doctor that you are using Taptiqom sine, as\u00a0timolol\u00a0can change the effects of some medicines used for anesthesia.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Taptiqom sine is not recommended for children or adolescents under 18 years of age as there is a lack of data on safety and efficacy in this age group.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Taptiqom sine<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Taptiqom sine can affect or be affected by other medicines you use.<\/p>\n\n\n\n<p>In particular, tell your doctor if you are using or intend to use:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>other\u00a0eye drops\u00a0for the treatment of\u00a0glaucoma<\/li><li>drugs to lower\u00a0blood pressure\u00a0et<\/li><li>heart medication<\/li><li>drugs for the treatment of\u00a0diabetes<\/li><li>quinidine\u00a0(used to treat heart disease and some types of\u00a0malaria\u00a0)<\/li><li>antidepressants called\u00a0fluoxetine\u00a0and\u00a0paroxetine.<\/li><\/ul>\n\n\n\n<p>If you are using other medicines\u00a0<strong>in the eye<\/strong>, wait at least 5 minutes after you have put in Taptiqom sine before using the other drug.<\/p>\n\n\n\n<p><strong>Contact lenses<\/strong><\/p>\n\n\n\n<p>Remove the contact lenses before using the eye drops and wait at least 15 minutes before putting the contact lenses back in.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, consult your doctor before using this medicine.\u00a0If you can become pregnant, you must use effective contraception during treatment with Taptiqom sine.\u00a0Do not use Taptiqom sine if you are pregnant, unless your doctor has told you to.\u00a0You should not use Taptiqom sine if you are breastfeeding.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Taptiqom sine may cause\u00a0side effects, such as blurred vision, which may affect your ability to drive and\/or operate machinery.\u00a0Wait to drive or use machines until you feel well and your vision is clear.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\u00a0side effects\u00a0.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Taptiqom sine contains phosphate<\/h2>\n\n\n\n<p>This medicine contains 1.3 mg\u00a0of phosphate\u00a0per ml.\u00a0If you have a severely damaged\u00a0cornea,\u00a0phosphate\u00a0can in very rare cases cause cloudy spots on the cornea due to the accumulation of\u00a0calcium\u00a0during treatment.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Taptiqom sine<\/h2>\n\n\n\n<p>Always use this medicine as directed by your doctor or pharmacist.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is 1 drop of Taptiqom sine in the eye or eyes once daily.&nbsp;Do not drip in more drops and do not use more often than prescribed by your doctor.&nbsp;This may make Taptiqom sine less effective.<\/p>\n\n\n\n<p>Only use Taptiqom sine in both eyes if your doctor has prescribed it.<\/p>\n\n\n\n<p>To be used only as\u00a0eye drops.\u00a0Do not swallow.<\/p>\n\n\n\n<p>Make sure that the tip of the multi-dose container does not touch the eye or the area around the eye.\u00a0It can damage your eye.\u00a0It can also lead to contamination with bacteria, which can cause\u00a0eye infections.\u00a0Such an\u00a0infection\u00a0can lead to serious eye damage, even loss of vision.\u00a0To avoid contamination of the multi-dose container, the tip of the multi-dose container should not touch other surfaces.<\/p>\n\n\n\n<p><strong>Instructions for use:<\/strong><\/p>\n\n\n\n<p>When using the bottle for the first time and before putting a drop in the eye, you should practice using the bottle.&nbsp;Gently press the bottle so that a drop comes out.&nbsp;Point the bottle away from the eye.<\/p>\n\n\n\n<p>When you are sure that you can drip one drop at a time, choose the position that feels most comfortable for you to drip the drops (you can sit, lie down on your back, or stand in front of a mirror).<\/p>\n\n\n\n<p>When starting a new bottle:<\/p>\n\n\n\n<p>Do not use the bottle if the plastic ring around the bottle neck is missing or broken.&nbsp;Write down the date you opened the bottle in the designated date space on the outer carton.<\/p>\n\n\n\n<p>Every time you use Taptiqom sine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>1. Wash your hands.<\/td><td>&nbsp;<\/td><\/tr><tr><td>2. When using the bottle for the first time, remove the sealing ring around the cap by pulling the tab.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20190328000104#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>3. Open the bottle by pulling off the cap.<\/td><td>&nbsp;<\/td><\/tr><tr><td>4. When\u00a0<strong>using the bottle for the first time<\/strong>, squeeze out one or more drops and discard them.<\/td><td>&nbsp;<\/td><\/tr><tr><td>5. Hold the bottle between your thumb and forefinger.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20190328000104#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>6. Tilt your head back or lie down.&nbsp;Place your hand on your forehead.&nbsp;Your index finger should be in line with your eyebrow.&nbsp;To avoid contamination of the solution, be especially careful not to touch the tip of the bottle to the eye, the skin around the eye, or the fingers.<\/td><td>&nbsp;<\/td><\/tr><tr><td>7. Pull down the lower eyelid with the other hand and look up.&nbsp;Gently press the bottle and let a drop fall into the space between the lower eyelid and the eye.&nbsp;Note that it may take a while before a drop comes out when you press the bottle.&nbsp;Do not press too hard.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20190328000104#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>8. Close the eye and press a finger on the inner corner of the eye for about two minutes.\u00a0This prevents the eye drop from flowing into the tear duct.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20190328000104#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>9. Wipe away any solution that may have ended up on the skin around the eye.&nbsp;This reduces the risk of skin darkening.<\/td><td>&nbsp;<\/td><\/tr><tr><td>10. Shake the bottle downward once to get rid of any remaining solution in the tip.&nbsp;Do not touch the tip or wipe it.<\/td><td><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20190328000104#\" rel=\"noopener\"><\/a><\/td><\/tr><tr><td>11. Put the cap on and close the bottle tightly.<\/td><td>&nbsp;<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>About 1 ml will remain, which cannot be dosed.&nbsp;Do not attempt to empty the bottle.<\/p>\n\n\n\n<p><strong>If a drop ends up outside the eye,<\/strong>&nbsp;try again.<\/p>\n\n\n\n<p><strong>If your doctor prescribed you to use drops in both eyes<\/strong>, repeat steps 7 to 9 for the other eye.<\/p>\n\n\n\n<p><strong>If you are using other medicines in the eye<\/strong>, wait at least 5 minutes after you have put in Taptiqom sine before using the other drug.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use too much Taptiqom sine&nbsp;<\/h2>\n\n\n\n<p>you may feel dizzy or have a headache, heart symptoms, or breathing problems.\u00a0If you have ingested too much medicine or, for example,\u00a0a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<p>Consult a doctor\u00a0<strong>if the medicine is accidentally swallowed<\/strong>.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Taptiqom sine<\/h2>\n\n\n\n<p>drip in a single drop as soon as you remember, then return to your routine.\u00a0However, if it is almost time for the next\u00a0dose, you can skip the missed\u00a0dose.\u00a0Do not take a double\u00a0dose\u00a0to make up for a missed\u00a0dose<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Do not stop using Taptiqom sine without asking your doctor<\/h2>\n\n\n\n<p>If you stop using Taptiqom sine, the pressure in the eye will increase again.&nbsp;This can cause permanent damage to the eye.<\/p>\n\n\n\n<p>If you have any further questions about this medicine, ask your doctor, pharmacist, or nurse.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.\u00a0Most\u00a0side effects\u00a0are not serious.<\/p>\n\n\n\n<p>You can usually continue to use the drops unless the\u00a0side effects\u00a0are severe.\u00a0If you are worried, talk to your doctor or pharmacist.<\/p>\n\n\n\n<p><strong>The following are known&nbsp;side effects&nbsp;when using Taptiqom sine:<\/strong><\/p>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(<\/strong>&nbsp;may affect up to 1 in 10 users):<\/p>\n\n\n\n<p>Eyes<\/p>\n\n\n\n<p>Itching\u00a0in the eye.\u00a0Eye irritation.\u00a0Eye pain.\u00a0Redness\u00a0in the eye.\u00a0Change in length, thickness, and number of\u00a0eyelashes.\u00a0The sensation of a foreign body in the eye.\u00a0Discoloration of the\u00a0eyelashes.\u00a0Light sensitivity.\u00a0Blurred vision.<\/p>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(<\/strong>&nbsp;may affect up to 1 in 100 users):<\/p>\n\n\n\n<p>Central and&nbsp;peripheral nervous system<\/p>\n\n\n\n<p>Headache.<\/p>\n\n\n\n<p>Eyes<\/p>\n\n\n\n<p>Dry eyes.&nbsp;Redness&nbsp;of the eyelids.&nbsp;Small spot-like inflamed areas on the surface of the eye.&nbsp;Watery eyes.&nbsp;Swollen eyelids.&nbsp;Tired eyes.&nbsp;Inflammation&nbsp;of the eyelids.&nbsp;Inflammation&nbsp;inside the eye.&nbsp;Eye discomfort.&nbsp;Eye allergy.&nbsp;Inflammation&nbsp;in the eye.&nbsp;Abnormal sensation in the eye.<\/p>\n\n\n\n<p><strong>The following&nbsp;side effects&nbsp;have been seen when using the medicines Taptiqom sine consists of (tafluprost and&nbsp;timolol&nbsp;) and may therefore occur when you use Taptiqom sine:<\/strong><\/p>\n\n\n\n<p><strong>The following&nbsp;side effects&nbsp;have been seen with tafluprost:<\/strong><\/p>\n\n\n\n<p>Eyes<\/p>\n\n\n\n<p>Impairment in the eye&#8217;s ability to see details.\u00a0Change in the color of the\u00a0iris\u00a0(may be permanent).\u00a0Change in color of the skin around the eyes.\u00a0Swelling of the surface membrane of the eye.\u00a0Eye discharge.\u00a0Pigmentation\u00a0of the surface membrane of the eye.\u00a0Follicles\u00a0in the surface membrane of the eye.\u00a0Sunken eyes.\u00a0Iritis\/uveitis (\u00a0inflammation\u00a0of the colored part of the eye).\u00a0Macular edema\/cystic macular edema (swelling of the retina of the eye leading to impaired vision).<\/p>\n\n\n\n<p>The skin<\/p>\n\n\n\n<p>Abnormal hair growth on the eyelids.<\/p>\n\n\n\n<p>Effects on the respiratory tract<\/p>\n\n\n\n<p>Worsened\u00a0asthma, shortness of breath.<\/p>\n\n\n\n<p><strong>The following&nbsp;side effects&nbsp;have been seen with timolol:<\/strong><\/p>\n\n\n\n<p>The immune system<\/p>\n\n\n\n<p>Allergic reactions, including swelling under the skin,\u00a0hives, and rash.\u00a0Severe sudden life-threatening\u00a0allergic reaction.\u00a0Itching.<\/p>\n\n\n\n<p>Metabolism&nbsp;and&nbsp;nutrition<\/p>\n\n\n\n<p>Low blood sugar.<\/p>\n\n\n\n<p>Mental disorders<\/p>\n\n\n\n<p>Depression.&nbsp;Difficulty sleeping.&nbsp;Nightmares.&nbsp;Memory loss.&nbsp;Nervousness.&nbsp;Hallucination.<\/p>\n\n\n\n<p>Central and&nbsp;peripheral nervous system<\/p>\n\n\n\n<p>Dizziness.\u00a0Fainting.\u00a0Unusual sensations (such as tingling and numbness).\u00a0Increases in signs and symptoms of\u00a0myasthenia gravis\u00a0(muscle disease).\u00a0Stroke.\u00a0Decreased blood supply to the brain.<\/p>\n\n\n\n<p>Eyes<\/p>\n\n\n\n<p>Inflammation\u00a0of the cornea.\u00a0Decreased sensation in the cornea.\u00a0Visual disturbances include refractive changes (sometimes due to discontinuation of miotic therapy).\u00a0Drooping upper eyelids.\u00a0Double vision.\u00a0Blurry vision and detachment of the blood vessel-containing membrane under the retina after filtration surgery, which can cause visual disturbances.\u00a0Corneal damage.<\/p>\n\n\n\n<p>Ears<\/p>\n\n\n\n<p>Tinnitus&nbsp;(ringing in the ears).<\/p>\n\n\n\n<p>The heart<\/p>\n\n\n\n<p>Slow heartbeat.&nbsp;Chest pain.&nbsp;Palpitation.&nbsp;Edema&nbsp;(fluid accumulation).&nbsp;Changes in&nbsp;pulse&nbsp;or heart rhythm.&nbsp;Chronic&nbsp;heart failure&nbsp;(heart disease with shortness of breath, swollen feet and legs due to fluid retention).&nbsp;A type of heart rhythm disorder.&nbsp;Heart attack.&nbsp;Heart failure&nbsp;.<\/p>\n\n\n\n<p>Blood vessels<\/p>\n\n\n\n<p>Low&nbsp;blood pressure&nbsp;.&nbsp;Limping.&nbsp;Raynaud&#8217;s phenomenon, cold hands and feet.<\/p>\n\n\n\n<p>Breath<\/p>\n\n\n\n<p>Spasm in the airways (preferably in people with existing disease).&nbsp;Difficulty breathing.&nbsp;Cough.<\/p>\n\n\n\n<p>Gastrointestinal tract<\/p>\n\n\n\n<p>Nausea.&nbsp;Indigestion.&nbsp;Diarrhea.&nbsp;Dry mouth&nbsp;.&nbsp;Taste changes.&nbsp;Abdominal pains.&nbsp;Vomiting.<\/p>\n\n\n\n<p>The skin<\/p>\n\n\n\n<p>Hair loss.&nbsp;Skin rash with a white to silvery appearance (psoriasis-like rash) or worsening&nbsp;psoriasis&nbsp;.&nbsp;Rash.<\/p>\n\n\n\n<p>Muscles and bones<\/p>\n\n\n\n<p>Muscle pain not caused by exercise.&nbsp;Joint pain.<\/p>\n\n\n\n<p>Reproductive organs and mammary gland<\/p>\n\n\n\n<p>Peyronie&#8217;s disease (which can cause bending of the penis).&nbsp;Sexual&nbsp;Dysfunction&nbsp;.&nbsp;Decreased&nbsp;libido&nbsp;.<\/p>\n\n\n\n<p>General symptoms<\/p>\n\n\n\n<p>Muscle weakness\/fatigue.&nbsp;Thirst.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Taptiqom sine<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the bottle label and the outer carton after &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store unopened bottles in a refrigerator (2 \u00b0C\u20138 \u00b0C).&nbsp;Do not freeze.<\/p>\n\n\n\n<p>Store the bottle in the original box.&nbsp;Light sensitive.<\/p>\n\n\n\n<p>After opening the bottle:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Store at a maximum of 25 \u00b0C.&nbsp;Do not freeze.<\/li><li>Store the bottle in the original box.&nbsp;Light sensitive.<\/li><li>To prevent&nbsp;infection&nbsp;, the bottle must be discarded no later than 3 months after it was opened for the first time.&nbsp;The 3 ml bottle is intended for 1 month of use, the 5 ml bottle is intended for 2 months and the 7 ml bottle is intended for 3 months.<\/li><\/ul>\n\n\n\n<p>Medicines must not be thrown into the drain or among household waste.&nbsp;Ask the pharmacist how to dispose of medicines that are no longer used.&nbsp;These measures will help to protect the environment.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are tafluprost and&nbsp;timolol&nbsp;.&nbsp;1 ml of solution contains 15 micrograms of tafluprost and 5 mg&nbsp;of timolol&nbsp;.<\/li><li>Other ingredients are&nbsp;glycerol&nbsp;, disodium phosphate dodecahydrate, disodium edetate, polysorbate 80,&nbsp;hydrochloric acid&nbsp;and\/or sodium hydroxide (to adjust&nbsp;pH&nbsp;) and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>Taptiqom sine is a clear, colorless liquid (solution), practically free of visible particles.&nbsp;It is supplied in packs containing either 1 clear plastic bottle of 3 ml, 5 ml or 7 ml, or 3 clear plastic bottles of 3 ml solution each.&nbsp;The plastic bottles are closed with a lid.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing authorization holder and manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Santen Oy<\/p>\n\n\n\n<p>Niittyhaankatu 20<\/p>\n\n\n\n<p>33720 Tampere<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Santen Oy<\/p>\n\n\n\n<p>Kelloportinkatu 1<\/p>\n\n\n\n<p>33100 Tampere<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p><strong>This medicine is authorized in the European Economic Area and in the United Kingdom (Northern Ireland) under the names:<\/strong><\/p>\n\n\n\n<p><strong>Tapticom:<\/strong><\/p>\n\n\n\n<p>Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, France, Germany, Greece, Hungary, Ireland, Latvia, Lithuania, Luxembourg, Netherlands, Portugal, Slovakia, Slovenia, Spain, United Kingdom (Northern Ireland)<\/p>\n\n\n\n<p><strong>Taptiqom sine:<\/strong>&nbsp;Denmark, Estonia, Finland, Iceland, Norway, Sweden<\/p>\n\n\n\n<p><strong>Taptiqom Multi:<\/strong>&nbsp;Poland<\/p>\n\n\n\n<p><strong>Loyada:<\/strong>&nbsp;Italy<\/p>\n","protected":false},"excerpt":{"rendered":"<p>15 micrograms\/ml + 5 mg\/ml\u00a0eye drops\u00a0, solution<br \/>\ntafluprost\/timolol<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[25405,25402,25211,25216,25400,25404,5029,5031,25212,25401,5030,25214,25403,8380],"class_list":["post-24420","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-benefits-of-tafluprost","tag-benefits-of-taptiqom-sine","tag-tafluprost","tag-tafluprost-side-effects","tag-taptiqom-sine","tag-taptiqom-sine-side-effects","tag-timolol","tag-timolol-side-effects","tag-what-is-tafluprost","tag-what-is-taptiqom-sine","tag-what-is-timolol","tag-what-tafluprost-is-used-for","tag-what-taptiqom-sine-is-used-for","tag-what-timolol-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24420","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=24420"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24420\/revisions"}],"predecessor-version":[{"id":24489,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24420\/revisions\/24489"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=24420"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=24420"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=24420"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}