{"id":24365,"date":"2022-08-22T11:01:20","date_gmt":"2022-08-22T11:01:20","guid":{"rendered":"https:\/\/zeepedia.com\/?p=24365"},"modified":"2022-08-23T11:42:26","modified_gmt":"2022-08-23T11:42:26","slug":"tamoxifen-mylan","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/tamoxifen-mylan\/","title":{"rendered":"Tamoxifen Mylan &#8211; Tamoxifen uses, dose and side effects"},"content":{"rendered":"\n<p>20 mg&nbsp;tablets<br>tamoxifen<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Tamoxifen Mylan is and what it is used for<\/h2>\n\n\n\n<p>Some\u00a0tumors\u00a0are dependent on the\u00a0hormone estrogen\u00a0for\u00a0their\u00a0growth.\u00a0Tamoxifen Mylan is a so-called anti-estrogen\u00a0that prevents the action of natural estrogen.<\/p>\n\n\n\n<p>Tamoxifen Mylan is used in breast cancer.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Tamoxifen Mylan<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Tamoxifen Mylan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (hypersensitive) to tamoxifen or any of the other ingredients in Tamoxifen Mylan).<\/li><li>if you are breastfeeding.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Tamoxifen Mylan:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have hereditary (inherited) angioedema because Tamoxifen Mylan may cause or worsen symptoms of hereditary\u00a0angioedema.\u00a0If you get symptoms such as\u00a0swelling of the face, lips, tongue, and\/or throat with difficulty swallowing or breathing, contact a doctor immediately.<\/li><\/ul>\n\n\n\n<p>Changes can occur in the lining of the uterus (endometrium), and some of them can be serious changes or even.&nbsp;cancer.&nbsp;Contact your doctor immediately if you experience any unusual vaginal bleeding or other gynecological symptoms (such as pain or pressure over the pelvis) while you are taking or have taken Tamoxifen Mylan.<\/p>\n\n\n\n<p>At the beginning of the treatment, some manifestations of the disease may become worse, e.g.&nbsp;pain may increase and\/or the diseased&nbsp;tissue&nbsp;may increase in size.&nbsp;If you also have severe nausea and vomiting, you should contact your doctor.&nbsp;The reason may be that the calcium content in the blood has changed, and the doctor should then take certain blood samples.<\/p>\n\n\n\n<p>Talk to your doctor if you think you have any of these or other problems with your medication.<\/p>\n\n\n\n<p><em>Stop taking Tamoxifen Mylan<\/em>&nbsp;and contact your doctor immediately if you experience any of the following symptoms (&nbsp;angioedema&nbsp;):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You find it difficult to breathe<\/li><li>You get swelling of the face, lips, tongue, and\/or throat which can make swallowing difficult<\/li><li>You get\u00a0hives<\/li><\/ul>\n\n\n\n<p>If you are admitted to the hospital, tell the healthcare staff that you are taking Tamoxifen Mylan.<\/p>\n\n\n\n<p>Tamoxifen Mylan can in rare cases affect the white\u00a0blood cells\u00a0so that the defense against infection deteriorates.\u00a0If you get an\u00a0infection\u00a0with symptoms such as fever with a greatly worsened general condition or fever with local infection symptoms such as sore throat\/pharynx\/mouth or vomiting, you should see a doctor as soon as possible so that a lack of\u00a0white blood cells\u00a0(\u00a0agranulocytosis\u00a0) can be ruled out via a blood test.\u00a0It is important that you then have information about your medication.<\/p>\n\n\n\n<p>In so-called late breast reconstruction (surgery that is done sometime after the first breast surgery to recreate a breast),\u00a0tissue\u00a0is moved to the breast from somewhere else on the body.\u00a0The use of Tamoxifen Mylan can then increase the risk of blood clots in the small\u00a0vessels\u00a0in the moved\u00a0tissue, which can lead to complications.<\/p>\n\n\n\n<p>Serious skin reactions including&nbsp;Stevens-Johnson syndrome&nbsp;and&nbsp;toxic epidermal necrolysis&nbsp;have been reported in association with treatment with Tamoxifen Mylan.&nbsp;Stop taking Tamoxifen Mylan and contact your doctor immediately if you notice any of the symptoms associated with the serious skin reactions described in section 4.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Tamoxifen Mylan<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including those obtained without a prescription.<\/p>\n\n\n\n<p>You must inform the doctor that you are taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>paroxetine,\u00a0fluoxetine\u00a0(for depression)<\/li><li>bupropion (for depression or smoking cessation)<\/li><li>quinidine\u00a0(used, among other things, in the treatment of\u00a0cardiac arrhythmias\u00a0)<\/li><li>cinacalcet (for the treatment of diseases of the parathyroid gland)<\/li><\/ul>\n\n\n\n<p>Concomitant use of these medicines should be avoided, as the effect of Tamoxifen Mylan may be reduced.<\/p>\n\n\n\n<p>Also, inform the doctor if you are taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>warfarin&nbsp;(blood thinners to prevent blood clots)<\/li><li>phenytoin&nbsp;(for&nbsp;epilepsy&nbsp;)<\/li><li>cytostatics (against cancer)<\/li><li>rifampicin (for&nbsp;tuberculosis&nbsp;)<\/li><\/ul>\n\n\n\n<p>Concomitant use of these medicines may mean that the doctor needs to raise or lower the\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n<p>Do not use Tamoxifen Mylan during pregnancy.&nbsp;There is a certain risk that the fetus will be affected.&nbsp;Before starting treatment, pregnancy must be ruled out.&nbsp;You should not become pregnant while taking Tamoxifen Mylan or within 9 months of stopping treatment.&nbsp;Birth control pills&nbsp;should not be used as contraception.&nbsp;Contact your doctor immediately if you think you are pregnant or for advice on contraception.<\/p>\n\n\n\n<p>It is not known whether Tamoxifen Mylan passes into breast milk.&nbsp;Tamoxifen Mylan should not be used during breastfeeding.&nbsp;Therefore, talk to your doctor before using Tamoxifen Mylan while breastfeeding.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving ability and use of machinery<\/h2>\n\n\n\n<p>Tamoxifen Mylan is unlikely to affect your ability to drive or use machines.&nbsp;However, fatigue has been reported with the use of Tamoxifen Mylan and while fatigue persists, caution must be exercised when driving or operating machinery.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\u00a0side effects.\u00a0Description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0Discuss with your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Tamoxifen Mylan contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;of sodium&nbsp;per tablet, i.e. it is almost &#8216;sodium-free&#8217;.<br><a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Tamoxifen Mylan<\/h2>\n\n\n\n<p>Always take Tamoxifen Mylan as directed by your doctor.\u00a0Your doctor will determine the\u00a0dose\u00a0that is right for you.\u00a0The usual daily\u00a0dose\u00a0is 20-40 mg which is taken once a day or is divided into 2 dosing occasions.\u00a0Take the medicine at the same time every day.\u00a0Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have taken too much Tamoxifen Mylan<\/h2>\n\n\n\n<p>Overdose can produce anti-estrogenic effects.\u00a0If you have ingested too much medicine, always contact your doctor or the nearest hospital for an assessment of the risk and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Tamoxifen Mylan<\/h2>\n\n\n\n<p>If you forget a\u00a0dose, take it as soon as you remember, then take the next\u00a0dose\u00a0at the right time.\u00a0Do not take 2\u00a0doses\u00a0at the same time<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Tamoxifen Mylan<\/h2>\n\n\n\n<p>Do not stop taking your medication unless your doctor advises you to stop.<\/p>\n\n\n\n<p>If you have further questions about this medicine, contact your doctor or pharmacist.<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, Tamoxifen Mylan can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Stop taking Tamoxifen Mylan and contact your doctor immediately or go to the nearest emergency department if you experience any of the following symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Reddish, non-raised, target-like, or round spots on the trunk, often with blisters in the center, scaly skin, and sores in the mouth, throat, nose, genitals, and eyes.\u00a0These severe skin rashes are preceded by fever and\u00a0flu-like symptoms\u00a0(\u00a0Stevens-Johnson syndrome\u00a0and toxic epidermal\u00a0necrolysis\u00a0) \u2013 these\u00a0side effects\u00a0are rare.<\/li><li>Swelling of the face, lips, tongue, or throat, difficulty swallowing or breathing (\u00a0angioedema\u00a0).\u00a0Tamoxifen Mylan can cause or worsen symptoms of hereditary\u00a0angioedema.<\/li><\/ul>\n\n\n\n<p><em>Very common (affects more than 1 in 10 users)<\/em>&nbsp;:<\/p>\n\n\n\n<p>Flushing, fluid retention, menstrual-like bleeding, vaginal discharge, nausea, rash, fatigue.<\/p>\n\n\n\n<p><em>Common (affects more than 1 in 100 users):<\/em><\/p>\n\n\n\n<p>Headache, dizziness, abnormal sensations (e.g. change in the way things taste and tingling\/tingling sensation in the skin),\u00a0anemia, blood clots (even in small blood vessels), vomiting, diarrhea, constipation, hair loss, vaginal itching, changes in the lining of the uterus, worsened blood supply to the brain, leg cramps, increased liver values, increased levels of fat in the blood,\u00a0hypersensitivity reaction, vision and eye changes, abnormally high-fat deposits in the liver, muscle pain.<\/p>\n\n\n\n<p><em>Uncommon (affects less than 1 in 100 users<\/em>&nbsp;):<\/p>\n\n\n\n<p>Cancer of the lining of the uterus, muscle knots in the uterus, increased risk of bleeding due to reduced number of\u00a0blood platelets\u00a0(\u00a0thrombocytes\u00a0), reduced number of\u00a0white blood cells\u00a0(\u00a0leukopenia\u00a0),\u00a0inflammation\u00a0of the pancreas (pain or tenderness in the upper part of the abdomen),\u00a0hives, liver cirrhosis,\u00a0inflammation\u00a0of the lungs with shortness of breath and cough, increased calcium levels in the blood.<\/p>\n\n\n\n<p><em>Rare (affects less than 1 in 1,000 users):<\/em><\/p>\n\n\n\n<p>Transient swelling of the ovaries, uterine cancer, ovarian cysts,\u00a0polyps\u00a0in the vagina, discomfort and\/or inflammation-like symptoms in the tumor area, skin and mucosal changes (sometimes severe), vasculitis, reduced number of\u00a0white blood cells\u00a0(\u00a0neutropenia,\u00a0agranulocytosis\u00a0see Warnings and precautions), biliary congestion, liver inflammation, liver cell damage, liver failure, liver cell death.\u00a0Endometriosis\u00a0can cause pain in the stomach and menstrual-like bleeding.\u00a0Optic nerve disease and inflammation of the optic nerve (which in a few cases has led to blindness).<\/p>\n\n\n\n<p>The following\u00a0side effects\u00a0have been reported as rare with other tamoxifen preparations: Loss of appetite, fatigue, constipation, anxiety, depression, confusion, and uterine cancer.<\/p>\n\n\n\n<p><em>Very rare (affects less than 1 in 10,000 users):<\/em><\/p>\n\n\n\n<p>Skin disease with rash and\u00a0redness\u00a0(a condition called\u00a0cutaneous\u00a0lupus erythematosus).\u00a0Porphyria cutanea tarda which is a type of metabolic disease\u00a0porphyria\u00a0that can cause symptoms such as skin reactions and hypersensitivity to sunlight.\u00a0Skin inflammation with red\u00a0swelling\u00a0and\/or blisters on the skin after radiation treatment, so-called radiation dermatitis<\/p>\n\n\n\n<p>See a doctor immediately if you experience sudden weakness and\/or paralysis in the arms or legs, sudden difficulty speaking, walking, difficulty holding things, or difficulty thinking.\u00a0These symptoms can occur due to impaired blood supply to the brain and be signs of a\u00a0stroke.<\/p>\n\n\n\n<p>If any of the&nbsp;side effects&nbsp;get worse or if you notice any&nbsp;side effects&nbsp;not mentioned in this information, contact your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Tamoxifen Mylan<\/h2>\n\n\n\n<p>Store in the original packaging.&nbsp;Light sensitive.<\/p>\n\n\n\n<p>Store out of sight and reach of children.<\/p>\n\n\n\n<p>Use before the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>The medicine must not be thrown into the drain or among the household waste.\u00a0Ask the pharmacist how to deal with medicines that are no longer used.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Contents declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is tamoxifen citrate corresponding to tamoxifen 20 mg per tablet.<\/li><li>Other ingredients are mannitol, corn starch, magnesium stearate, croscarmellose sodium<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Appearance and package sizes of the medicine<\/h2>\n\n\n\n<p>The tablet is white and curved with a diameter of 9.5 mm.\u00a0The tablet has a score and is marked TN\/20 on one side and G on the other side.<\/p>\n\n\n\n<p><em>Package size:<\/em><\/p>\n\n\n\n<p>100 tablets<\/p>\n\n\n\n<p>250 tablets<a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Mylan AB<\/p>\n\n\n\n<p>Box 23033<\/p>\n\n\n\n<p>104 35 Stockholm<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Delpharm Lille SAS<\/p>\n\n\n\n<p>Parc d&#8217;activit\u00e9s de Roubaix Est<\/p>\n\n\n\n<p>22 Rue de Toufflers<\/p>\n\n\n\n<p>CS50070<\/p>\n\n\n\n<p>59452&nbsp;Lys&nbsp;Lez Lannoy<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p>Mylan Hungary Kft.\/Mylan Hungary Ltd.<\/p>\n\n\n\n<p>Mylan utca 1.,<\/p>\n\n\n\n<p>Kom\u00e1rom, 2900,<\/p>\n\n\n\n<p>Hungary<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Some\u00a0tumors\u00a0are dependent on the\u00a0hormone estrogen\u00a0for\u00a0their\u00a0growth.\u00a0Tamoxifen Mylan is a so-called anti-\u00a0estrogen\u00a0that prevents the action of natural estrogen.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,22500],"tags":[25311,25323,25327,25326,25313,25310,25309,25324,25314,25325],"class_list":["post-24365","post","type-post","status-publish","format-standard","hentry","category-medicines","category-t","tag-tamoxifen","tag-tamoxifen-mylan","tag-tamoxifen-mylan-side-effects","tag-tamoxifen-mylan-tablet","tag-tamoxifen-side-effects","tag-tamoxifen-tablet","tag-what-is-tamoxifen","tag-what-is-tamoxifen-mylan","tag-what-tamoxifen-is-used-for","tag-what-tamoxifen-mylan-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24365","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=24365"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24365\/revisions"}],"predecessor-version":[{"id":24408,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/24365\/revisions\/24408"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=24365"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=24365"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=24365"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}